| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Neeraj Kumar, Kondusamy Ambasankar, Kishore Kumar Krishnani, Shashi Bhushan, Paramjit Singh Minha. Dietary Pyridoxine Protects against Stress and Maintains Immunohaematological Status in Chanos chanos Exposed to Endosulfan. Basic & clinical pharmacology & toxicology. vol 119. issue 3. 2017-03-09. PMID:27038044. |
the effect of dietary pyridoxine supplementation was studied in terms of antioxidative enzymes (catalase, superoxide dismutase, glutathione-s-transferase), stress markers [heat-shock protein 70, caspase-3, cortisol, acetylcholine esterase (ache), blood glucose], immunohaematological parameters (total protein, albumin, globulin and a/g ratio, nitroblue tetrazolium, rbc, wbc, hb), gill histopathology and a subsequent challenge study with vibrio parahaemolyticus. |
2017-03-09 |
2023-08-13 |
Not clear |
| Catarina Duarte, Patrícia Napoleão, Teresa Freitas, Carlota Saldanh. An ex vivo study of nitric oxide efflux from human erythrocytes in both genders. Clinical hemorheology and microcirculation. vol 64. issue 4. 2017-03-09. PMID:27767976. |
it is also known that binding of acetylcholine (ach) with ache on erythrocyte membrane initiates a signal transduction mechanism that stimulates nitric oxide (no) efflux. |
2017-03-09 |
2023-08-13 |
human |
| Jean Froment, Kevin V Thomas, Knut Erik Tollefse. Automated high-throughput in vitro screening of the acetylcholine esterase inhibiting potential of environmental samples, mixtures and single compounds. Ecotoxicology and environmental safety. vol 130. 2017-03-07. PMID:27085000. |
a high-throughput and automated assay for testing the presence of acetylcholine esterase (ache) inhibiting compounds was developed, validated and applied to screen different types of environmental samples. |
2017-03-07 |
2023-08-13 |
Not clear |
| Syed Mohd Danish Rizvi, Sibhghatulla Shaikh, Deeba Naaz, Shazi Shakil, Adnan Ahmad, Mohd Haneef, Adel M Abuzenada. Kinetics and Molecular Docking Study of an Anti-diabetic Drug Glimepiride as Acetylcholinesterase Inhibitor: Implication for Alzheimer's Disease-Diabetes Dual Therapy. Neurochemical research. vol 41. issue 6. 2017-03-06. PMID:26886763. |
therefore, the present study was carried out to find whether glimepiride, an oral antidiabetic drug which is a pparγ agonist could inhibit the activity of acetylcholine esterase (ache) enzyme. |
2017-03-06 |
2023-08-13 |
Not clear |
| Syed Mohd Danish Rizvi, Sibhghatulla Shaikh, Deeba Naaz, Shazi Shakil, Adnan Ahmad, Mohd Haneef, Adel M Abuzenada. Kinetics and Molecular Docking Study of an Anti-diabetic Drug Glimepiride as Acetylcholinesterase Inhibitor: Implication for Alzheimer's Disease-Diabetes Dual Therapy. Neurochemical research. vol 41. issue 6. 2017-03-06. PMID:26886763. |
actually, ache inhibitors seize the breakdown of acetylcholine which forms the main therapeutic strategy for ad. |
2017-03-06 |
2023-08-13 |
Not clear |
| Syed Mohd Danish Rizvi, Sibhghatulla Shaikh, Deeba Naaz, Shazi Shakil, Adnan Ahmad, Mohd Haneef, Adel M Abuzenada. Kinetics and Molecular Docking Study of an Anti-diabetic Drug Glimepiride as Acetylcholinesterase Inhibitor: Implication for Alzheimer's Disease-Diabetes Dual Therapy. Neurochemical research. vol 41. issue 6. 2017-03-06. PMID:26886763. |
glimepiride was found to interact with ache enzyme at the same locus as that of substrate acetylcholine iodide (achi). |
2017-03-06 |
2023-08-13 |
Not clear |
| Nidhi Chauhan, Sheetal Chawla, C S Pundir, Utkarsh Jai. An electrochemical sensor for detection of neurotransmitter-acetylcholine using metal nanoparticles, 2D material and conducting polymer modified electrode. Biosensors & bioelectronics. vol 89. issue Pt 1. 2017-03-01. PMID:27342368. |
an essential biological sensor for acetylcholine (ach) detection is constructed by immobilizing enzymes, acetylcholinesterase (ache) and choline oxidase (cho), on the surface of iron oxide nanoparticles (fe |
2017-03-01 |
2023-08-13 |
Not clear |
| Roman Roy, Flavia Niccolini, Gennaro Pagano, Marios Politi. Cholinergic imaging in dementia spectrum disorders. European journal of nuclear medicine and molecular imaging. vol 43. issue 7. 2017-02-24. PMID:26984612. |
spect and pet studies using selective radioligands for cholinergic markers, such as [(11)c]mp4a and [(11)c]pmp pet for acetylcholinesterase (ache), [(123)i]5ia spect for the α4β2 nicotinic acetylcholine receptor and [(123)i]ibvm spect for the vesicular acetylcholine transporter, have been developed in an attempt to clarify those aspects of the diseases that remain unclear. |
2017-02-24 |
2023-08-13 |
Not clear |
| Emin Garibov, Parham Taslimi, Afsun Sujayev, Zeynebe Bingol, Songul Çetinkaya, İlhami Gulçin, Sukru Beydemir, Vagif Farzaliyev, Saleh H Alwasel, Claudiu T Supura. Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activities. Journal of enzyme inhibition and medicinal chemistry. vol 31. issue sup3. 2017-02-23. PMID:27329935. |
these cyclic thioureas showed good inhibitory action against acetylcholine esterase (ache), butyrylcholine esterase (bche), and human (h) carbonic anhydrase (ca) isoforms i and ii. |
2017-02-23 |
2023-08-13 |
human |
| Satinderpal Singh, Atish Prakash, Shamsherjit Kaur, Long Chiau Ming, Vasudevan Mani, Abu Bakar Abdul Majee. The role of multifunctional drug therapy as an antidote to combat experimental subacute neurotoxicity induced by organophosphate pesticides. Environmental toxicology. vol 31. issue 8. 2017-02-16. PMID:25864908. |
the results showed that chronic administration of cpf significantly impaired learning and memory, along with motor coordination, and produced a marked increase in oxidative stress along with significantly reduced acetylcholine esterase (ache) activity. |
2017-02-16 |
2023-08-13 |
rat |
| Roobakkumar Amsalingam, Prabu Gajjeraman, Nisha Sam, Vattakandy Jasin Rahman, Babu Azaria. Mechanism of Fenpropathrin Resistance in Red Spider Mite, Oligonychus coffeae (Acarina: Tetranychidae), Infesting Tea [Camellia sinensis L. (O. Kuntze)]. Applied biochemistry and biotechnology. vol 181. issue 2. 2017-02-06. PMID:27604837. |
the development of acaricide (fenpropathrin) resistance has been screened in field populations (fps) of rsms from different tea-growing regions of south india and compared with a laboratory-susceptible population (sp) based on toxicity bioassay, detoxifying enzyme activities, analysis of acetylcholine esterase gene (ache, 2064 bp), and their expression pattern using semiquantitative rt-pcr. |
2017-02-06 |
2023-08-13 |
spider |
| Kitlangki Suchiang, Ramesh Sharm. Age-dependent modulation of fasting and long-term dietary restriction on acetylcholinesterase in non-neuronal tissues of mice. Molecular and cellular biochemistry. vol 419. issue 1-2. 2017-02-01. PMID:27379505. |
acetylcholinesterase (ache), a thoroughly studied enzyme better known for hydrolyzing acetylcholine (ach) in neuronal tissues, has recently been linked with multiple unrelated biological functions in different non-neuronal tissues. |
2017-02-01 |
2023-08-13 |
mouse |
| Heidi Q Xie, Tuan Xu, Yangsheng Chen, Yunping Li, Yingjie Xia, Sherry L Xu, Lingyun Wang, Karl W K Tsim, Bin Zha. New perspectives for multi-level regulations of neuronal acetylcholinesterase by dioxins. Chemico-biological interactions. vol 259. issue Pt B. 2017-01-30. PMID:27374124. |
acetylcholinesterase (ache; ec 3.1.1.7) is a vital functional enzyme in cholinergic neurotransmission which can rapidly hydrolyze neurotransmitter, acetylcholine, in the central and peripheral nervous systems. |
2017-01-30 |
2023-08-13 |
mouse |
| Dae Cheol Nam, Yu Mi Ha, Min Kyu Park, Sung Kweon Ch. The rs662 polymorphism of paraoxonase 1 affects the difference in the inhibition of butyrylcholinesterase activity by organophosphorus pesticides in human blood. International journal of clinical pharmacology and therapeutics. vol 54. issue 8. 2017-01-27. PMID:27087156. |
ops inhibit acetylcholinesterase (ache) at nerve endings and accumulate acetylcholine (ach) at these sites. |
2017-01-27 |
2023-08-13 |
human |
| Cho Rong Kim, Soo Jung Choi, Yoon Kyung Kwon, Jae Kyeom Kim, Youn-Jung Kim, Gwi Gun Park, Dong-Hoon Shi. Cinnamomum loureirii Extract Inhibits Acetylcholinesterase Activity and Ameliorates Trimethyltin-Induced Cognitive Dysfunction in Mice. Biological & pharmaceutical bulletin. vol 39. issue 7. 2017-01-27. PMID:27374288. |
the pathogenesis of alzheimer's disease (ad) has been linked to the deficiency of neurotransmitter acetylcholine (ach) in the brain, and the main treatment strategy for improving ad symptoms is the inhibition of acetylcholinesterase (ache) activity. |
2017-01-27 |
2023-08-13 |
mouse |
| Masatoshi Inden, Kazuyuki Takata, Daijiro Yanagisawa, Eishi Ashihara, Ikuo Tooyama, Shun Shimohama, Yoshihisa Kitamur. α4 nicotinic acetylcholine receptor modulated by galantamine on nigrostriatal terminals regulates dopamine receptor-mediated rotational behavior. Neurochemistry international. vol 94. 2017-01-19. PMID:26911419. |
galantamine, an acetylcholine esterase (ache) inhibitor used to treat dementia symptoms, also acts as an allosteric potentiating ligand (apl) at nicotinic acetylcholine receptors (nachrs). |
2017-01-19 |
2023-08-13 |
rat |
| Katsuyoshi Mizukami, Hiroyasu Akatsu, Eric E Abrahamson, Zhiping Mi, Milos D Ikonomovi. Immunohistochemical analysis of hippocampal butyrylcholinesterase: Implications for regional vulnerability in Alzheimer's disease. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 36. issue 2. 2017-01-09. PMID:26293308. |
studies of acetylcholine degrading enzymes acetylcholinesterase (ache) and butyrylcholinesterase (bche) in alzheimer's disease (ad) have suggested their potential role in the development of fibrillar amyloid-β (aβ) plaques (amyloid plaques). |
2017-01-09 |
2023-08-13 |
Not clear |
| Peng Li, Ya-Ling Yin, Mo-Li Zhu, Guo-Pin Pan, Fan-Rong Zhao, Jun-Xiu Lu, Zhan Liu, Shuang-Xi Wang, Chang-Ping H. Chronic administration of isocarbophos induces vascular cognitive impairment in rats. Journal of cellular and molecular medicine. vol 20. issue 4. 2017-01-06. PMID:26818681. |
long-term administration of isocarbophos reduced the hippocampal acetylcholinesterase (ache) activity and acetylcholine (ach) content but did not alter the plasma ache activity, and significantly damaged the functions of learning and memory. |
2017-01-06 |
2023-08-13 |
rat |
| Souksanh Nouanthavong, Duangjai Nacapricha, Charles S Henry, Yupaporn Sameeno. Pesticide analysis using nanoceria-coated paper-based devices as a detection platform. The Analyst. vol 141. issue 5. 2017-01-04. PMID:26842266. |
in the presence of acetylcholine, ache and chox catalyze the formation of h2o2, which is detected colorimetrically by a nanoceria-coated device resulting in the formation of a yellow color. |
2017-01-04 |
2023-08-13 |
Not clear |
| Juan Zou, Pei-Shan Cai, Chao-Mei Xiong, Jin-Lan Rua. Neuroprotective effect of peptides extracted from walnut (Juglans Sigilata Dode) proteins on Aβ25-35-induced memory impairment in mice. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 36. issue 1. 2016-12-30. PMID:26838735. |
to further explore the underlying mechanisms of the neuroprotectivity of walnut peptides, the activities of superoxide dismutase (sod), glutathione (gsh), acetylcholine esterase (ache), and the content of malondialdehyde (mda) as well as the level of nitric oxide (no) in the hippocampus of mice were measured by spectrophotometric method. |
2016-12-30 |
2023-08-13 |
mouse |