| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caio R D Assis, Amanda G Linhares, Mariana P Cabrera, Vagne M Oliveira, Kaline C C Silva, Marina Marcuschi, Elba V M Maciel Carvalho, Ranilson S Bezerra, Luiz B Carvalh. Erythrocyte acetylcholinesterase as biomarker of pesticide exposure: new and forgotten insights. Environmental science and pollution research international. vol 25. issue 19. 2018-12-20. PMID:29797194. |
acetylcholinesterase (ache) acts on the hydrolysis of acetylcholine, rapidly removing this neurotransmitter at cholinergic synapses and neuromuscular junctions as well as in neuronal growth and differentiation, modulation of cell adhesion ("electrotactins") and aryl-acylamidase activity (aaa). |
2018-12-20 |
2023-08-13 |
Not clear |
| Yasser El-Nahhal, Raed Lubba. Acute and single repeated dose effects of low concentrations of chlorpyrifos, diuron, and their combination on chicken. Environmental science and pollution research international. vol 25. issue 11. 2018-12-11. PMID:29397503. |
the effects were determined as biological response (chicken behavior); physiological response (body weight, gaining weight); and biochemical response such as reduction of acetylcholine esterase activity (ache), changes in liver biomarkers, such as (1) alkaline phosphatase (alp), (2) aspartate aminotransferase (ast), and (3) alanine aminotransferase (alp), and effects on kidney biomarkers such as total protein, creatinine, uric acid, and urea. |
2018-12-11 |
2023-08-13 |
chicken |
| Vivitri Prasasty, Muhammad Radifar, Enade Istyaston. Natural Peptides in Drug Discovery Targeting Acetylcholinesterase. Molecules (Basel, Switzerland). vol 23. issue 9. 2018-12-11. PMID:30217053. |
acetylcholinesterase-inhibitory peptide has gained much importance since it can inhibit acetylcholinesterase (ache) and increase the availability of acetylcholine in cholinergic synapses, enhancing cholinergic transmission in pharmacological treatment of alzheimer's disease (ad). |
2018-12-11 |
2023-08-13 |
Not clear |
| M Ender Avci, Ayse Gokce Keskus, Seniye Targen, M Efe Isilak, Mehmet Ozturk, Rengul Cetin Atalay, Michelle M Adams, Ozlen Kon. Development of a novel zebrafish xenograft model in ache mutants using liver cancer cell lines. Scientific reports. vol 8. issue 1. 2018-11-26. PMID:29371671. |
acetylcholinesterase (ache), an enzyme responsible for degradation of acetylcholine, has been identified as a prognostic marker in liver cancer. |
2018-11-26 |
2023-08-13 |
mouse |
| Sheemona Chowdhary, Rajasri Bhattacharyya, Dibyajyoti Banerje. 1-Naphthyl acetate: A chromogenic substrate for the detection of erythrocyte acetylcholinesterase activity. Biochimie. vol 154. 2018-11-26. PMID:30201403. |
the alternative substrates for ache were screened in terms of high goldscore and favorable tie in comparison to acetylcholine (ach)-ache complex and other relevant esterases. |
2018-11-26 |
2023-08-13 |
Not clear |
| Narayanan Gobi, Baskaralingam Vaseeharan, Ravichandran Rekha, Sekar Vijayakumar, Caterina Faggi. Bioaccumulation, cytotoxicity and oxidative stress of the acute exposure selenium in Oreochromis mossambicus. Ecotoxicology and environmental safety. vol 162. 2018-11-20. PMID:29990726. |
we also observed inhibition of acetylcholine esterase (ache) activity in brain tissue of fish exposed to se for higher concentrations. |
2018-11-20 |
2023-08-13 |
cat |
| Avigail Baruch Leshem, Sivan Isaacs, Sachin K Srivastava, Ibrahim Abdulhalim, Ariel Kushmaro, Hanna Rapapor. Quantitative assessment of paraoxon adsorption to amphiphilic β-sheet peptides presenting the catalytic triad of esterases. Journal of colloid and interface science. vol 530. 2018-11-12. PMID:29982025. |
organophosphate compounds that are used as pesticides affect the nervous system by binding irreversibly to the active site of the enzyme acetylcholine esterase (ache) and disrupting neuro-signaling nerve cells. |
2018-11-12 |
2023-08-13 |
Not clear |
| M D Baldissera, C F Souza, P H Doleski, K L S Moreira, M L da Veiga, M I U M da Rocha, R C V Santos, B Baldisserott. Involvement of cholinergic and adenosinergic systems on the branchial immune response of experimentally infected silver catfish with Streptococcus agalactiae. Journal of fish diseases. vol 41. issue 1. 2018-11-08. PMID:28699699. |
it has been recognized that the cholinergic and adenosinergic systems have an essential role in immune and inflammatory responses during bacterial fish pathogens, such as the enzymes acetylcholinesterase (ache) and adenosine deaminase (ada), which are responsible for catalysis of the anti-inflammatory molecules acetylcholine (ach) and adenosine (ado) respectively. |
2018-11-08 |
2023-08-13 |
Not clear |
| Morteza Shahriari, Arash Zibaee, Najmeh Sahebzadeh, Leila Shamakh. Effects of α-pinene, trans-anethole, and thymol as the essential oil constituents on antioxidant system and acetylcholine esterase of Ephestia kuehniella Zeller (Lepidoptera: Pyralidae). Pesticide biochemistry and physiology. vol 150. 2018-11-01. PMID:30195386. |
the current study aimed to determine the potential effects of three essential oil constituents, α-pinene, trans-anethole, and thymol, on antioxidant system and acetylcholine esterase (ache) of ephestia kuehniella zeller. |
2018-11-01 |
2023-08-13 |
Not clear |
| Tecush Mohammadi, Yousef Ghaye. Atomic insight into designed carbamate-based derivatives as acetylcholine esterase (AChE) inhibitors: a computational study by multiple molecular docking and molecular dynamics simulation. Journal of biomolecular structure & dynamics. vol 36. issue 1. 2018-10-15. PMID:27924680. |
atomic insight into designed carbamate-based derivatives as acetylcholine esterase (ache) inhibitors: a computational study by multiple molecular docking and molecular dynamics simulation. |
2018-10-15 |
2023-08-13 |
Not clear |
| Xiaochun Guo, Shengnan Zhang, Shaoyong Lu, Binghui Zheng, Ping Xie, Jun Chen, Guangyu Li, Chunsheng Liu, Qin Wu, Houcheng Cheng, Nan San. Perfluorododecanoic acid exposure induced developmental neurotoxicity in zebrafish embryos. Environmental pollution (Barking, Essex : 1987). vol 241. 2018-10-05. PMID:30029309. |
additionally, the acetylcholine (ach) content as well as acetylcholinesterase (ache) activity were determined to be significantly downregulated in pfdoa treatment groups. |
2018-10-05 |
2023-08-13 |
zebrafish |
| Jeong Su Ha, Jong Min Kim, Seon Kyeong Park, Jin Yong Kang, Du Sang Lee, Uk Lee, Dae-Ok Kim, Sung-Gil Choi, Ho Jin He. Anti-amyloidogenic properties of an ethyl acetate fraction from Actinidia arguta in Aβ Food & function. vol 9. issue 6. 2018-10-01. PMID:29786737. |
furthermore, efaa showed the ameliorating effect of cholinergic functions by increasing acetylcholine (ach) levels and decreasing acetylcholinesterase (ache) activity, and protected antioxidant systems by increasing superoxide dismutase (sod) and decreasing the oxidized glutathione (gsh)/total gsh and malondialdehyde (mda) in the brain. |
2018-10-01 |
2023-08-13 |
mouse |
| Dinithi Champika Peiris, Thamali Dhanushk. Low doses of chlorpyrifos interfere with spermatogenesis of rats through reduction of sex hormones. Environmental science and pollution research international. vol 24. issue 26. 2018-09-25. PMID:28721614. |
another two sets of (four groups/set; n = 10) animals were orally treated with the same doses of cpf, control animal groups were treated with distilled water only for 30 days, and fertility indices and blood plasma acetylcholine esterase (ache) were determined on day 31. |
2018-09-25 |
2023-08-13 |
human |
| A Kroth, V Mackedanz, C Matté, A T S Wyse, M F M Ribeiro, W A Partat. Effect of Sciatic Nerve Transection on acetylcholinesterase activity in spinal cord and skeletal muscles of the bullfrog Lithobates catesbeianus. Brazilian journal of biology = Revista brasleira de biologia. vol 78. issue 2. 2018-09-05. PMID:28977043. |
in some vertebrate tissues, this condition decreases acetylcholinesterase (ache) activity, the enzyme responsible for fast hydrolysis of released acetylcholine in cholinergic synapses. |
2018-09-05 |
2023-08-13 |
rat |
| Yongliang Zhang, Qiong Wang, Hailong Chen, Xinmin Liu, Ke Lv, Tingmei Wang, Yanli Wang, Guohua Ji, Hongqing Cao, Guanghan Kan, Yinghui Li, Lina Q. Involvement of Cholinergic Dysfunction and Oxidative Damage in the Effects of Simulated Weightlessness on Learning and Memory in Rats. BioMed research international. vol 2018. 2018-09-04. PMID:29581965. |
besides, acetylcholine esterase (ache) activity, malondialdehyde (mda) level in brain, reactive oxygen species (ros), and 8-hydroxy-2-deoxyguanosine (8-ohdg) concentrations of hu rats were significantly increased. |
2018-09-04 |
2023-08-13 |
rat |
| Qingqing Zhang, Yufang Hu, Di Wu, Shaohua Ma, Jiao Wang, Jiajia Rao, Lihua Xu, Huan Xu, Huili Shao, Zhiyong Guo, Sui Wan. Protein-mimicking nanowire-inspired electro-catalytic biosensor for probing acetylcholinesterase activity and its inhibitors. Talanta. vol 183. 2018-09-03. PMID:29567174. |
this sensing strategy involves the reaction of acetylcholine chloride (ach) with acetylcholinesterase (ache) to form choline that is in turn catalytically oxidized by choline oxidase (chox) to produce hydrogen peroxide (h |
2018-09-03 |
2023-08-13 |
Not clear |
| You-Na Lee, Koichi Okumura, Tomoko Horio, Tatsuya Iwata, Kazuhiro Takahashi, Toshiaki Hattori, Kazuaki Sawad. A bio-image sensor for simultaneous detection of multi-neurotransmitters. Talanta. vol 179. 2018-08-31. PMID:29310276. |
apyrase and acetylcholinesterase (ache), as selective elements, are used to recognize adenosine 5'-triphosphate (atp) and acetylcholine (ach), respectively. |
2018-08-31 |
2023-08-13 |
Not clear |
| Ariana Beste, DeCarlos E Taylor, Tsung-Ming Shih, Thaddeus P Thoma. Mechanisms of acetylcholinesterase protection against sarin and soman by adenosine A Computational biology and chemistry. vol 75. 2018-08-29. PMID:29747078. |
mechanisms of acetylcholinesterase protection against sarin and soman by adenosine a organophosphorus nerve agents (nas) irreversibly inhibit acetylcholinesterase (ache), the enzyme responsible for breaking down the neurotransmitter acetylcholine (ach). |
2018-08-29 |
2023-08-13 |
Not clear |
| G A Toledo-Ibarra, E J Rodríguez-Sánchez, H G Ventura-Ramón, K J G Díaz-Resendiz, M I Girón-Pére. Cholinergic alterations by exposure to pesticides used in control vector: Guppies fish (Poecilia reticulta) as biological model. International journal of environmental health research. vol 28. issue 1. 2018-08-27. PMID:29380629. |
subsequently, acetylcholinesterase activity (ache) and acetylcholine concentrations (ach) in muscle tissue were determined. |
2018-08-27 |
2023-08-13 |
Not clear |
| Mark P Gunderson, Brandon T Nguyen, Juan C Cervantes Reyes, Laura L Holden, John M T French, Brandon D Smith, Connor Lineberge. Response of phase I and II detoxification enzymes, glutathione, metallothionein and acetylcholine esterase to mercury and dimethoate in signal crayfish (Pacifastacus leniusculus). Chemosphere. vol 208. 2018-08-22. PMID:29902759. |
we examined the effects of mercury and the organophosphate pesticide dimethoate on erod, mrod, glutathione s-transferase (gst), acetylcholine esterase (ache), metallothionein (mt) and glutathione (gsh) in the signal crayfish (pacifastacus leniusculus). |
2018-08-22 |
2023-08-13 |
Not clear |