| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miranda L Xu, Wilson K W Luk, Cathy W C Bi, Etta Y L Liu, Kevin Q Y Wu, Ping Yao, Tina T X Dong, Karl W K Tsi. Erythropoietin regulates the expression of dimeric form of acetylcholinesterase during differentiation of erythroblast. Journal of neurochemistry. vol 146. issue 4. 2019-06-26. PMID:29675901. |
acetylcholinesterase (ache; ec 3.1.1.7) is known to hydrolyze acetylcholine at cholinergic synapses. |
2019-06-26 |
2023-08-13 |
Not clear |
| Levent Cavas, Gamze Topcam, Cevher Gundogdu-Hizliates, Yavuz Ergu. Neural Network Modeling of AChE Inhibition by New Carbazole-Bearing Oxazolones. Interdisciplinary sciences, computational life sciences. vol 11. issue 1. 2019-06-25. PMID:29236214. |
acetylcholine esterase (ache) is one of the targeted enzymes in the therapy of important neurodegenerative diseases such as alzheimer's disease. |
2019-06-25 |
2023-08-13 |
Not clear |
| Agung Nugroho, Jong-Hyuk Park, Jae Sue Choi, Kyoung-Sik Park, Joon-Pyo Hong, Hee-Juhn Par. Structure determination and quantification of a new flavone glycoside with anti-acetylcholinesterase activity from the herbs of Elsholtzia ciliata. Natural product research. vol 33. issue 6. 2019-06-20. PMID:29224362. |
acetylcholinesterase (ache) inhibition activity was assayed to find anti-alzheimer's activity, since this enzyme increases the concentration of acetylcholine (ach), a neurotransmitter, responsible for brain's memory. |
2019-06-20 |
2023-08-13 |
Not clear |
| Mamangam Subaraja, Arambakkam Janardhanam Vanisre. Aberrant neurotransmissional mRNAs in cerebral ganglions of rotenone-exposed Lumbricus terrestris exhibiting motor dysfunction and altered cognitive behavior. Environmental science and pollution research international. vol 26. issue 14. 2019-06-19. PMID:30868461. |
gaba, cholinergic receptor, serotonin transporter (sert), acetylcholine esterase (ache), and dopamine-β-hydroxylase that are well known for their involvement in neuromuscular junctions were investigated by qrt-pcr. |
2019-06-19 |
2023-08-13 |
Not clear |
| Snezana Agatonovic-Kustrin, Ella Kustrin, Vladimir Gegechkori, David W Morto. High-Performance Thin-Layer Chromatography Hyphenated with Microchemical and Biochemical Derivatizations in Bioactivity Profiling of Marine Species. Marine drugs. vol 17. issue 3. 2019-06-17. PMID:30832418. |
high-performance thin-layer chromatography (hptlc) hyphenated with microchemical (dpph•, p-anisaldehyde, and fast blue b) and biochemical (α-amylase and acetylcholine esterase (ache) enzymatic) derivatizations was used to evaluate antioxidant activity, presence of phytosterols and phenolic lipids, α-amylase and ache inhibitory activities of extract components. |
2019-06-17 |
2023-08-13 |
Not clear |
| Rami B Kassab, Maha S Lokman, Ehab A Essaw. Neurochemical alterations following the exposure to di-n-butyl phthalate in rats. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30446882. |
in addition, the levels of norepinephrine (ne), dopamine (da) and acetylcholine esterase (ache) activity were decreased. |
2019-06-06 |
2023-08-13 |
rat |
| Jing Zhao, Dejun Hao, Liubin Xiao, Yongan Tan, Yiping Jiang, Lixin Bai, Kai Wan. Molecular and functional properties of two Spodoptera exigua acetylcholinesterase genes. Archives of insect biochemistry and physiology. vol 101. issue 3. 2019-06-06. PMID:31033012. |
acetylcholinesterase (ache) is a vital enzyme that hydrolyzes acetylcholine. |
2019-06-06 |
2023-08-13 |
Not clear |
| Hassan M Albishri, Deia Abd El-Had. Hyphenation of enzyme/graphene oxide-ionic liquid/glassy carbon biosensors with anodic differential pulse stripping voltammetry for reliable determination of choline and acetylcholine in human serum. Talanta. vol 200. 2019-06-06. PMID:31036163. |
in the current work, sensitive and selective biosensors composed of choline oxidase (cho) and/or acetylcholine esterase (ache) on graphene oxide-ionic liquid (go-il)/ glassy carbon electrode (gce) hyphenated with anodic differential pulse stripping voltammetry (adpsv) were firstly established for the determination of ach and ch in human serum samples. |
2019-06-06 |
2023-08-13 |
human |
| Zafer Sahin, Merve Ertas, Ceysu Bender, Emre F Bülbül, Barkin Berk, Sevde N Biltekin, Leyla Yurttaş, Şeref Demiraya. Thiazole-substituted benzoylpiperazine derivatives as acetylcholinesterase inhibitors. Drug development research. vol 79. issue 8. 2019-06-05. PMID:30343499. |
hit, lead & candidate discovery after acetylcholine is released into the synaptic cleft, it is reabsorbed or deactivated by acetylcholinesterase (ache). |
2019-06-05 |
2023-08-13 |
Not clear |
| Xiuxia Song, Maohua Miao, Xiaoyu Zhou, Dekun Li, Youping Tian, Hong Liang, Runsheng Li, Wei Yua. Bisphenol A Exposure and Sperm ACHE Hydroxymethylation in Men. International journal of environmental research and public health. vol 16. issue 1. 2019-05-08. PMID:30626059. |
the acetylcholinesterase (ache) gene is a sperm-expressed gene encoding the acetylcholine hydrolyzing enzyme acetylcholinesterase and participates in the apoptosis of cells, including sperm. |
2019-05-08 |
2023-08-13 |
human |
| Neeraj Kumar, K K Krishnani, Narendra Pratap Sing. Oxidative and Cellular Metabolic Stress of Fish: An Appealing Tool for Biomonitoring of Metal Contamination in the Kolkata Wetland, a Ramsar Site. Archives of environmental contamination and toxicology. vol 76. issue 3. 2019-05-02. PMID:30607445. |
the biochemical marker as antioxidative status, i.e., catalase, superoxide dismutase (sod), and glutathione-s-transferase (gst) in liver and gill, were remarkably higher (p < 0.01) at some of the sampling sites, but catalase in brain, sod in kidney, gst in brain and kidney, and neurotransmitter as acetylcholine esterase (ache) in brain were not significant (p > 0.05) among the sampling sites. |
2019-05-02 |
2023-08-13 |
Not clear |
| Hafiz Muhammad Tahir, Tayyba Basheer, Shaukat Ali, Rabia Yaqoob, Sajida Naseem, Shafaat Yar Kha. Effect of Pesticides on Biological Control Potential of Neoscona theisi (Araneae: Araneidae). Journal of insect science (Online). vol 19. issue 2. 2019-05-02. PMID:30915446. |
the present study was designed to record the effect of λ-cyhalothrin, bifenthrin, and glyphosate on the mortality, avoidance behavior, foraging activity, and activity of acetylcholine esterase (ache) and carboxylesterase (care) in neoscona theisi (walckenaer, 1841). |
2019-05-02 |
2023-08-13 |
spider |
| Mridula Saxena, Ragini Dube. Target Enzyme in Alzheimer's Disease: Acetylcholinesterase Inhibitors. Current topics in medicinal chemistry. vol 19. issue 4. 2019-04-24. PMID:30706815. |
the enzyme acetylcholinesterase enzyme (ache) is the key enzyme in the hydrolysis of the neurotransmitter acetylcholine and is also the target of most of the clinically used drugs for the treatment of ad but these drugs provide only symptomatic treatment and have the limitation of loss of therapeutic efficacy with time. |
2019-04-24 |
2023-08-13 |
Not clear |
| Maria Domenica Alvau, Stefano Tartaggia, Anna Meneghello, Bruno Casetta, Giammario Calia, Pier Andrea Serra, Federico Polo, Giuseppe Toffol. Enzyme-Based Electrochemical Biosensor for Therapeutic Drug Monitoring of Anticancer Drug Irinotecan. Analytical chemistry. vol 90. issue 10. 2019-04-17. PMID:29658266. |
cpt-11 was also found to directly inhibit acetylcholine esterase (ache), an enzyme involved in neuromuscular junction. |
2019-04-17 |
2023-08-13 |
cattle |
| Juan Wang, Zhiyue Lv, Ziyan Lei, Zhaoyang Chen, Bo Lv, Huilin Yang, Zhi Wang, Qisheng Son. Expression and functional analysis of cytochrome P450 genes in the wolf spider Pardosa pseudoannulata under cadmium stress. Ecotoxicology and environmental safety. vol 172. 2019-04-11. PMID:30669070. |
in addition, the increase in metallothionein (mt) content and glutathione peroxidase (gpx) activity and decrease in total acetylcholine esterase (ache) activity were also detected. |
2019-04-11 |
2023-08-13 |
spider |
| Qiyun Wu, Aster H Y Fung, Miranda L Xu, Kaman Poon, Etta Y L Liu, Xiang P Kong, Ping Yao, Qing P Xiong, Tina T X Dong, Karl W K Tsi. Microphthalmia-associated transcription factor up-regulates acetylcholinesterase expression during melanogenesis of murine melanoma cells. The Journal of biological chemistry. vol 293. issue 37. 2019-04-09. PMID:30076217. |
acetylcholinesterase (ache) hydrolyzes the neurotransmitter acetylcholine in neurons. |
2019-04-09 |
2023-08-13 |
Not clear |
| Ruiwen Li, Hengqi Wang, Chuang Mi, Chenglian Feng, Ling Zhang, Lihua Yang, Bingsheng Zho. The adverse effect of TCIPP and TCEP on neurodevelopment of zebrafish embryos/larvae. Chemosphere. vol 220. 2019-04-05. PMID:30612050. |
furthermore, our results suggest that tcipp and tcep showed no effects on acetylcholine content or ache activity, which were considered as the main targets of cpf. |
2019-04-05 |
2023-08-13 |
zebrafish |
| Yao-Guo Han, Xiong Qin, Tao Zhang, Ming Lei, Fang-Yuan Sun, Jing-Jing Sun, Wei-Fang Yua. Electroacupuncture prevents cognitive impairment induced by lipopolysaccharide via inhibition of oxidative stress and neuroinflammation. Neuroscience letters. vol 683. 2019-03-11. PMID:29885447. |
ea prevented lps-induced decrease of α7nachr protein, acetylcholine (ach) content and choline acetyltransferase (chat) activity, and prevented lps-induced increase of acetylcholinesterase (ache) activity (p < 0.05). |
2019-03-11 |
2023-08-13 |
mouse |
| Jamshed Iqbal, Muhammad S A Abbasi, Sumera Zaib, Saifullah Afridi, Norbert Furtmann, Jürgen Bajorath, Peter Lange. Identification of New Chromenone Derivatives as Cholinesterase Inhibitors and Molecular Docking Studies. Medicinal chemistry (Shariqah (United Arab Emirates)). vol 14. issue 8. 2019-03-05. PMID:29473519. |
this devastating disorder is generally associated with the gradual memory loss, specified by a decrease of acetylcholine level in the cortex hippocampus of the brain due to hyperactivation of cholinesterases (acetylcholinesterase (ache) and butyrylcholinesterase (bche)). |
2019-03-05 |
2023-08-13 |
Not clear |
| Adriana Ferreira Lopes Vilela, Cláudia Seidl, Juliana Maria Lima, Carmen Lúcia Cardos. An improved immobilized enzyme reactor-mass spectrometry-based label free assay for butyrylcholinesterase ligand screening. Analytical biochemistry. vol 549. 2019-03-05. PMID:29550345. |
acetylcholinesterase (ache) and butyrylcholinesterase (bche) are key cholinesterase enzymes responsible for the hydrolysis of acetylcholine into choline and acetic acid, an essential process for the restoration of the cholinergic neuron. |
2019-03-05 |
2023-08-13 |
Not clear |