| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Burgin, Szczupa. Basal acetylcholine release in leech ganglia depolarizes neurons through receptors with a nicotinic binding site The Journal of experimental biology. vol 201 (Pt 12). 2019-11-20. PMID:9600872. |
the results suggest the existence of a basal level of acetylcholine (ach) release in the leech ganglion that is powerfully counteracted by endogenous ache activity. |
2019-11-20 |
2023-08-12 |
Not clear |
| J Kuchinka, Monika Chrzanowska, T Kude. Adrenergic and cholinergic innervation of the atrioventricular valves in chinchilla (Chinchilla laniger). Folia morphologica. vol 76. issue 4. 2019-11-20. PMID:28553858. |
the dissected valves were stained entirely using the modified histochemical acetylcholine esterase technique (ache) and the spg-de la torre method. |
2019-11-20 |
2023-08-13 |
Not clear |
| Noam Cohen, Einat Toister, Yonatan Lati, Meni Girshengorn, Lilach Levin, Lea Silberstein, Dror Seliktar, Eyal Epstei. Cell encapsulation utilizing PEG-fibrinogen hydrogel supports viability and enhances productivity under stress conditions. Cytotechnology. vol 70. issue 3. 2019-11-20. PMID:29468479. |
here, we utilized a uniquely fabricated semi-synthetic 3d polyethylene glycol-fibrinogen (peg-fb) hydrogel scaffold, which exhibits both high stability and high bioactivity, to encapsulate hek293 cells for the production of human recombinant acetylcholine esterase (ache). |
2019-11-20 |
2023-08-13 |
human |
| Masahiro Tabuchi, Keiko Fujikura, Sakae Inou. Histochemistry of acetylcholine receptors and acetylcholinesterase during the formation of neuromuscular junctions in the urodele Hynobius nigrescens. Journal of morphology. vol 207. issue 1. 2019-11-20. PMID:29865493. |
the development and structure of neuromuscular junctions (n-m-js) in stylopodia of forelimbs of larvae and adults of hynobius nigrescens were histochemically investigated for acetylcholine receptors (achrs) and acetylcholinesterase (ache) activity. |
2019-11-20 |
2023-08-13 |
Not clear |
| Yulong Lin, Yalin Wang, Jie Lv, Nannan Wang, Jing Wang, Meng L. Targeted acetylcholinesterase-responsive drug carriers with long duration of drug action and reduced hepatotoxicity. International journal of nanomedicine. vol 14. 2019-11-01. PMID:31440049. |
design and synthesis of ache inhibitors that increase the cholinergic transmission by blocking the degradation of acetylcholine can serve as a strategy for the treatment of ache-associated disease. |
2019-11-01 |
2023-08-13 |
Not clear |
| Jean-Marie Graïc, Livio Corain, Antonella Peruffo, Bruno Cozzi, Dick F Swaa. The bovine anterior hypothalamus: Characterization of the vasopressin-oxytocin containing nucleus and changes in relation to sexual differentiation. The Journal of comparative neurology. vol 526. issue 17. 2019-10-28. PMID:30255945. |
in an effort to systematically describe the neurochemical anatomy of the bovine anterior hypothalamus, we used a series of immunocytochemical markers such as acetylcholine esterase (ache), arginine-vasopressin (avp), calbindin (calb), galanin (gal), neuropeptide-y (npy), oxytocin (oxt), somatostatin (sst), and vasoactive intestinal peptide (vip). |
2019-10-28 |
2023-08-13 |
cattle |
| Eng Leng Saw, Yoshihiko Kakinuma, Martin Fronius, Rajesh Katar. The non-neuronal cholinergic system in the heart: A comprehensive review. Journal of molecular and cellular cardiology. vol 125. 2019-10-28. PMID:30343172. |
the existence of cardiac nncs has been confirmed by the presence of cholinergic markers in the cardiomyocytes, which are crucial for synthesis (choline acetyltransferase, chat), storage (vesicular acetylcholine transporter, vacht), reuptake of choline for synthesis (high-affinity choline transporter, cht1) and degradation (acetylcholinesterase, ache) of acetylcholine (ach). |
2019-10-28 |
2023-08-13 |
Not clear |
| Shan Huang, Jiandong Yao, Xu Chu, Yi Liu, Qi Xiao, Yue Zhan. One-Step Facile Synthesis of Nitrogen-Doped Carbon Dots: A Ratiometric Fluorescent Probe for Evaluation of Acetylcholinesterase Activity and Detection of Organophosphorus Pesticides in Tap Water and Food. Journal of agricultural and food chemistry. vol 67. issue 40. 2019-10-21. PMID:31532667. |
upon the addition of ache and choline oxidase, acetylcholine was catalyzed to produce choline that was further oxidized to produce h |
2019-10-21 |
2023-08-13 |
human |
| Kishwar Sultana, Muhammad Kashif Zahoor, Muhammad Sagheer, - Farha. Efficacy of Chrozophora plicata and Trianthema portuclacastrum weed plant extracts against Trogoderma granarium Everts under laboratory conditions. Pakistan journal of pharmaceutical sciences. vol 32. issue 1. 2019-10-15. PMID:30772803. |
a decrease in the activity of acetylcholine esterase (ache), acid phosphatase (acp), alkaline phosphatase (akp), α-carboxyl and β-carboxyl was also found. |
2019-10-15 |
2023-08-13 |
Not clear |
| C David Andersson, Nicolas Martinez, Dominik Zeller, Anders Allgardsson, Michael M Koza, Bernhard Frick, Fredrik Ekström, Judith Peters, Anna Linusso. Influence of Enantiomeric Inhibitors on the Dynamics of Acetylcholinesterase Measured by Elastic Incoherent Neutron Scattering. The journal of physical chemistry. B. vol 122. issue 36. 2019-10-11. PMID:30110543. |
the enzyme acetylcholinesterase (ache) is essential in humans and animals because it catalyzes the breakdown of the nerve-signaling substance acetylcholine. |
2019-10-11 |
2023-08-13 |
Not clear |
| Ji Eun Kim, Ji Won Park, Mi Ju Kang, Hyeon Jun Choi, Su Ji Bae, Yusang Choi, Young Ju Lee, Sungbaek Seo, Jin Tae Hong, Dae Youn Hwan. Laxative Effect of Spicatoside A by Cholinergic Regulation of Enteric Nerve in Loperamide-Induced Constipation: ICR Mice Model. Molecules (Basel, Switzerland). vol 24. issue 5. 2019-10-07. PMID:30836659. |
furthermore, significant improvements were observed in the acetylcholinesterase (ache) activity and acetylcholine receptors' (achrs) downstream signaling pathway after treatment of spia. |
2019-10-07 |
2023-08-13 |
mouse |
| Nermin Eissa, Sheikh Azimullah, Petrilla Jayaprakash, Richard L Jayaraj, David Reiner, Shreesh K Ojha, Rami Beiram, Holger Stark, Dorota Łażewska, Katarzyna Kieć-Kononowicz, Bassem Sade. The dual-active histamine H3 receptor antagonist and acetylcholine esterase inhibitor E100 ameliorates stereotyped repetitive behavior and neuroinflammmation in sodium valproate induced autism in mice. Chemico-biological interactions. vol 312. 2019-10-07. PMID:31369746. |
histamine h3 receptor (h3r) and acetylcholine esterase (ache) are involved in several cognitive disorders such as alzheimer's disease, schizophrenia, anxiety, and narcolepsy, all of which are comorbid with asd. |
2019-10-07 |
2023-08-13 |
mouse |
| Robert Josef Nachlinger, Vivien Kauschke, Katja Trinkaus, Thaqif El Khassawna, Christian Heiss, Katrin Susanne Lip. Application of donepezil increased collagen 1 expression in mesenchymal stroma cells of an ovine osteoporosis model. Journal of musculoskeletal & neuronal interactions. vol 18. issue 3. 2019-09-30. PMID:30179213. |
donepezil inhibits the acetylcholine degradation molecule acetylcholinesterase (ache). |
2019-09-30 |
2023-08-13 |
Not clear |
| Julie V Miller, Ryan F LeBouf, Kimberly A Kelly, Lindsay T Michalovicz, Anand Ranpara, Alicia R Locker, Diane B Miller, James P O'Callagha. The Neuroinflammatory Phenotype in a Mouse Model of Gulf War Illness is Unrelated to Brain Regional Levels of Acetylcholine as Measured by Quantitative HILIC-UPLC-MS/MS. Toxicological sciences : an official journal of the Society of Toxicology. vol 165. issue 2. 2019-09-25. PMID:29846716. |
although inhibition of ache leading to accumulation of acetylcholine (ach) will activate the cholinergic anti-inflammatory pathway, the signature symptomatology of gwi has been shown to be associated with neuroinflammation. |
2019-09-25 |
2023-08-13 |
mouse |
| Jia Xu, Xiaotong Hu, Habib Khan, Miaomiao Tian, Li Yan. Converting solution viscosity to distance-readout on paper substrates based on enzyme-mediated alginate hydrogelation: Quantitative determination of organophosphorus pesticides. Analytica chimica acta. vol 1071. 2019-09-16. PMID:31128750. |
the method is accomplished with the aid of the inhibition effect of target samples on the ache enzyme-catalyzed hydrolysis of acetylcholine, which changes the ph value of the solution to release ca |
2019-09-16 |
2023-08-13 |
Not clear |
| Aisa Ozawa, Erina Kadowaki, Tomoyo Horio, Motoharu Sakau. Acetylcholine suppresses the increase of glia fibrillary acidic protein expression via acetylcholine receptors in cAMP-induced astrocytic differentiation of rat C6 glioma cells. Neuroscience letters. vol 698. 2019-09-10. PMID:30639397. |
we previously demonstrated that the inhibition of acetylcholine esterase (ache) suppressed the differentiation of rat glioma c6 cells, an astrocyte differentiation model, and we observed a suppressive effect of ach agonists on astrocyte differentiation. |
2019-09-10 |
2023-08-13 |
rat |
| Aliya R Mukhametgalieva, Aliya R Aglyamova, Sofya V Lushchekina, Marko Goličnik, Patrick Masso. Time-course of human cholinesterases-catalyzed competing substrate kinetics. Chemico-biological interactions. vol 310. 2019-09-09. PMID:31247192. |
for ache, acetylcholine was competing with visible substrates. |
2019-09-09 |
2023-08-13 |
human |
| Zhi-Pu Yu, Yin-Yin Wang, Shu-Juan Yu, Jie Bao, Jin-Hai Yu, Hua Zhan. Absolute structure assignment of an iridoid-monoterpenoid indole alkaloid hybrid from Dipsacus asper. Fitoterapia. vol 135. 2019-09-03. PMID:31051193. |
our biological evaluations showed that compound 2 exhibited moderate inhibition against acetylcholine esterase (ache) with an ic |
2019-09-03 |
2023-08-13 |
Not clear |
| Muhammed Khairujjaman Mazumder, Shuvasish Choudhur. Tea polyphenols as multi-target therapeutics for Alzheimer's disease: An in silico study. Medical hypotheses. vol 125. 2019-08-27. PMID:30902161. |
with neurodegeneration, the level of the neurotransmitter acetylcholine (ach), as well as acetylcholinesterase (ache), decreases in the synaptic cleft, called cholinergic deficiency. |
2019-08-27 |
2023-08-13 |
Not clear |
| Nehad E M Taktak, Mohamed E I Badaw. Potential of hydrocarbon and oxygenated monoterpenes against Culex pipiens larvae: Toxicity, biochemical, pharmacophore modeling and molecular docking studies. Pesticide biochemistry and physiology. vol 158. 2019-08-23. PMID:31378352. |
in addition, in vivo biochemical studies including effects on acetylcholine esterase (ache), acid and alkaline phosphatases (acp and alp), total adenosine triphosphatase (atpase) and gamma-aminobutyric acid transaminase (gaba-t) were investigated. |
2019-08-23 |
2023-08-13 |
Not clear |