| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiuxia Song, Maohua Miao, Xiaoyu Zhou, Dekun Li, Youping Tian, Hong Liang, Runsheng Li, Wei Yua. Bisphenol A Exposure and Sperm ACHE Hydroxymethylation in Men. International journal of environmental research and public health. vol 16. issue 1. 2019-05-08. PMID:30626059. |
the acetylcholinesterase (ache) gene is a sperm-expressed gene encoding the acetylcholine hydrolyzing enzyme acetylcholinesterase and participates in the apoptosis of cells, including sperm. |
2019-05-08 |
2023-08-13 |
human |
| Neeraj Kumar, K K Krishnani, Narendra Pratap Sing. Oxidative and Cellular Metabolic Stress of Fish: An Appealing Tool for Biomonitoring of Metal Contamination in the Kolkata Wetland, a Ramsar Site. Archives of environmental contamination and toxicology. vol 76. issue 3. 2019-05-02. PMID:30607445. |
the biochemical marker as antioxidative status, i.e., catalase, superoxide dismutase (sod), and glutathione-s-transferase (gst) in liver and gill, were remarkably higher (p < 0.01) at some of the sampling sites, but catalase in brain, sod in kidney, gst in brain and kidney, and neurotransmitter as acetylcholine esterase (ache) in brain were not significant (p > 0.05) among the sampling sites. |
2019-05-02 |
2023-08-13 |
Not clear |
| Hafiz Muhammad Tahir, Tayyba Basheer, Shaukat Ali, Rabia Yaqoob, Sajida Naseem, Shafaat Yar Kha. Effect of Pesticides on Biological Control Potential of Neoscona theisi (Araneae: Araneidae). Journal of insect science (Online). vol 19. issue 2. 2019-05-02. PMID:30915446. |
the present study was designed to record the effect of λ-cyhalothrin, bifenthrin, and glyphosate on the mortality, avoidance behavior, foraging activity, and activity of acetylcholine esterase (ache) and carboxylesterase (care) in neoscona theisi (walckenaer, 1841). |
2019-05-02 |
2023-08-13 |
spider |
| Mridula Saxena, Ragini Dube. Target Enzyme in Alzheimer's Disease: Acetylcholinesterase Inhibitors. Current topics in medicinal chemistry. vol 19. issue 4. 2019-04-24. PMID:30706815. |
the enzyme acetylcholinesterase enzyme (ache) is the key enzyme in the hydrolysis of the neurotransmitter acetylcholine and is also the target of most of the clinically used drugs for the treatment of ad but these drugs provide only symptomatic treatment and have the limitation of loss of therapeutic efficacy with time. |
2019-04-24 |
2023-08-13 |
Not clear |
| Maria Domenica Alvau, Stefano Tartaggia, Anna Meneghello, Bruno Casetta, Giammario Calia, Pier Andrea Serra, Federico Polo, Giuseppe Toffol. Enzyme-Based Electrochemical Biosensor for Therapeutic Drug Monitoring of Anticancer Drug Irinotecan. Analytical chemistry. vol 90. issue 10. 2019-04-17. PMID:29658266. |
cpt-11 was also found to directly inhibit acetylcholine esterase (ache), an enzyme involved in neuromuscular junction. |
2019-04-17 |
2023-08-13 |
cattle |
| Juan Wang, Zhiyue Lv, Ziyan Lei, Zhaoyang Chen, Bo Lv, Huilin Yang, Zhi Wang, Qisheng Son. Expression and functional analysis of cytochrome P450 genes in the wolf spider Pardosa pseudoannulata under cadmium stress. Ecotoxicology and environmental safety. vol 172. 2019-04-11. PMID:30669070. |
in addition, the increase in metallothionein (mt) content and glutathione peroxidase (gpx) activity and decrease in total acetylcholine esterase (ache) activity were also detected. |
2019-04-11 |
2023-08-13 |
spider |
| Qiyun Wu, Aster H Y Fung, Miranda L Xu, Kaman Poon, Etta Y L Liu, Xiang P Kong, Ping Yao, Qing P Xiong, Tina T X Dong, Karl W K Tsi. Microphthalmia-associated transcription factor up-regulates acetylcholinesterase expression during melanogenesis of murine melanoma cells. The Journal of biological chemistry. vol 293. issue 37. 2019-04-09. PMID:30076217. |
acetylcholinesterase (ache) hydrolyzes the neurotransmitter acetylcholine in neurons. |
2019-04-09 |
2023-08-13 |
Not clear |
| Ruiwen Li, Hengqi Wang, Chuang Mi, Chenglian Feng, Ling Zhang, Lihua Yang, Bingsheng Zho. The adverse effect of TCIPP and TCEP on neurodevelopment of zebrafish embryos/larvae. Chemosphere. vol 220. 2019-04-05. PMID:30612050. |
furthermore, our results suggest that tcipp and tcep showed no effects on acetylcholine content or ache activity, which were considered as the main targets of cpf. |
2019-04-05 |
2023-08-13 |
zebrafish |
| Yao-Guo Han, Xiong Qin, Tao Zhang, Ming Lei, Fang-Yuan Sun, Jing-Jing Sun, Wei-Fang Yua. Electroacupuncture prevents cognitive impairment induced by lipopolysaccharide via inhibition of oxidative stress and neuroinflammation. Neuroscience letters. vol 683. 2019-03-11. PMID:29885447. |
ea prevented lps-induced decrease of α7nachr protein, acetylcholine (ach) content and choline acetyltransferase (chat) activity, and prevented lps-induced increase of acetylcholinesterase (ache) activity (p < 0.05). |
2019-03-11 |
2023-08-13 |
mouse |
| Jamshed Iqbal, Muhammad S A Abbasi, Sumera Zaib, Saifullah Afridi, Norbert Furtmann, Jürgen Bajorath, Peter Lange. Identification of New Chromenone Derivatives as Cholinesterase Inhibitors and Molecular Docking Studies. Medicinal chemistry (Shariqah (United Arab Emirates)). vol 14. issue 8. 2019-03-05. PMID:29473519. |
this devastating disorder is generally associated with the gradual memory loss, specified by a decrease of acetylcholine level in the cortex hippocampus of the brain due to hyperactivation of cholinesterases (acetylcholinesterase (ache) and butyrylcholinesterase (bche)). |
2019-03-05 |
2023-08-13 |
Not clear |
| Adriana Ferreira Lopes Vilela, Cláudia Seidl, Juliana Maria Lima, Carmen Lúcia Cardos. An improved immobilized enzyme reactor-mass spectrometry-based label free assay for butyrylcholinesterase ligand screening. Analytical biochemistry. vol 549. 2019-03-05. PMID:29550345. |
acetylcholinesterase (ache) and butyrylcholinesterase (bche) are key cholinesterase enzymes responsible for the hydrolysis of acetylcholine into choline and acetic acid, an essential process for the restoration of the cholinergic neuron. |
2019-03-05 |
2023-08-13 |
Not clear |
| S J Brooks, C Escudero-Oñate, T Gomes, L Ferrando-Climen. An integrative biological effects assessment of a mine discharge into a Norwegian fjord using field transplanted mussels. The Science of the total environment. vol 644. 2019-03-01. PMID:30743819. |
the biomarkers used included: condition index (ci); stress on stress (sos); micronuclei formation (mn); acetylcholine esterase (ache) inhibition, lipid peroxidation (lpo) and neutral lipid (nl) accumulation. |
2019-03-01 |
2023-08-13 |
Not clear |
| Chanika Alahakoon, Tharaka L Dassanayake, Indika B Gawarammana, E Michael Sedgwick, Vajira S Weerasinghe, Ahmed Abdalla, Michael S Roberts, Nicholas A Buckle. Prediction of organophosphorus insecticide-induced intermediate syndrome with stimulated concentric needle single fibre electromyography. PloS one. vol 13. issue 9. 2019-02-25. PMID:30261032. |
ops inhibit acetylcholine esterase (ache), leading to over-activity of muscarinic and nicotinic cholinergic circuits. |
2019-02-25 |
2023-08-13 |
Not clear |
| Hans-Peter Hutter, Michael Kundi, Kathrin Lemmerer, Michael Poteser, Lisbeth Weitensfelder, Peter Wallner, Hanns Moshamme. Subjective Symptoms of Male Workers Linked to Occupational Pesticide Exposure on Coffee Plantations in the Jarabacoa Region, Dominican Republic. International journal of environmental research and public health. vol 15. issue 10. 2019-02-15. PMID:30257443. |
significantly increased symptom frequencies were related to neurotoxicity, parasympathic effects and acetylcholine esterase inhibition, with the highest differences found for excessive salivation, dizziness and stomach ache. |
2019-02-15 |
2023-08-13 |
Not clear |
| Xinhai Ye, Liwen Yang, David Stanley, Fei Li, Qi Fan. Two Bombyx mori acetylcholinesterase genes influence motor control and development in different ways. Scientific reports. vol 7. issue 1. 2019-02-01. PMID:28694460. |
among its other biological roles, acetylcholinesterase (ache, ec 3.1.1.7), encoded by two ace in most insects, catalyses the breakdown of acetylcholine, thereby terminating synaptic transmission. |
2019-02-01 |
2023-08-13 |
Not clear |
| Neeraj Kumar, Kishore Kumar Krishnani, Narendra Pratap Sing. Comparative study of selenium and selenium nanoparticles with reference to acute toxicity, biochemical attributes, and histopathological response in fish. Environmental science and pollution research international. vol 25. issue 9. 2019-01-23. PMID:29332272. |
cat, sod, and gst were significantly elevated (p < 0.01) when exposed to se and se-nps, and similarly, a neurotransmitter enzyme (acetylcholine esterase (ache)) was significantly inhibited in a time- and dose-dependent manner. |
2019-01-23 |
2023-08-13 |
cat |
| Tabassum Hossain, Achintya Saha, Arup Mukherje. Exploring molecular structural requirement for AChE inhibition through multi-chemometric and dynamics simulation analyses. Journal of biomolecular structure & dynamics. vol 36. issue 5. 2019-01-21. PMID:28417668. |
acetylcholine (ach) acts through the regulation of ache activity, which can play a key role in accelerating senile amyloid β-peptide (aβ) plaque deposition. |
2019-01-21 |
2023-08-13 |
Not clear |
| N Samad, A Saleem, F Yasmin, M A Shehza. Quercetin protects against stress-induced anxiety- and depression-like behavior and improves memory in male mice. Physiological research. vol 67. issue 5. 2019-01-09. PMID:30044120. |
administration of quer decreased ache in unstressed, while levels of acetylcholine were increased in vehicle and quer treated stressed animals. |
2019-01-09 |
2023-08-13 |
mouse |
| Xin-Chen Wang, Yu-Min Xu, Hong-Ying Li, Chun-Ying Wu, Ting-Ting Xu, Na-Chuan Luo, Shi-Jie Zhang, Qi Wang, Shi-Jian Qua. Jiao-Tai-Wan Improves Cognitive Dysfunctions through Cholinergic Pathway in Scopolamine-Treated Mice. BioMed research international. vol 2018. 2019-01-08. PMID:30050927. |
in addition, the activity of acetylcholinesterase (ache) was effectively decreased; the activity of choline acetyltransferase (chat) and concentration of acetylcholine (ach) were improved after jtw treatment in both hippocampus and cortex of scop-treated mice. |
2019-01-08 |
2023-08-13 |
mouse |
| Hoda E Mohamed, Dina M Abo-ELmatty, Noha M Mesbah, Samy M Saleh, Abdel-Moniem A Ali, Amr T Sak. Raspberry ketone preserved cholinergic activity and antioxidant defense in obesity induced Alzheimer disease in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 107. 2019-01-03. PMID:30257330. |
it inhibited acetylcholinesterase enzyme (ache) and hence increased acetylcholine level (ach) in brain tissues of o-ad rats. |
2019-01-03 |
2023-08-13 |
rat |