| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huixin Chen, Xiang Wu, Xinmei Gu, Yiying Zhou, Luying Ye, Ke Zhang, Hanbo Pan, Jialing Wang, Hua Wei, Binbin Zhu, C Benjamin Naman, Shinghung Mak, Paul R Carlier, Wei Cui, Yifan Ha. Tacrine(10)-Hupyridone Prevents Post-operative Cognitive Dysfunction via the Activation of BDNF Pathway and the Inhibition of AChE in Aged Mice. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30483056. |
furthermore, a10e substantially enhanced choline acetyltransferase (chat)-positive area and decreased ache activity, in the hippocampus regions of surgery-treated mice, indicating that a10e could prevent surgery-induced dysfunction of cholinergic system, possibly via increasing the synthesis of acetylcholine and the inhibition of ache. |
2020-09-30 |
2023-08-13 |
mouse |
| Adriana M Dos Santos, Ariele C Moreira, Bianca Rebelo Lopes, Mariana F Fracola, Fernando G de Almeida, Odair C Bueno, Quezia B Cass, Dulce Helena F Souz. Acetylcholinesterases from Leaf-Cutting ant Enzyme research. vol 2019. 2020-09-30. PMID:31354985. |
acetylcholinesterases from leaf-cutting ant acetylcholinesterase (ache) is responsible for catalyzing the hydrolysis of the neurotransmitter acetylcholine (ach) leading to acetate and choline (ch) release. |
2020-09-30 |
2023-08-13 |
Not clear |
| Adam Kostelnik, Alexander Cegan, Miroslav Pohank. Acetylcholinesterase Inhibitors Assay Using Colorimetric pH Sensitive Strips and Image Analysis by a Smartphone. International journal of analytical chemistry. vol 2017. 2020-09-29. PMID:28286520. |
ache degrades acetylcholine into choline and acetic acid which causes color change of acid-base indicator. |
2020-09-29 |
2023-08-13 |
Not clear |
| Qing-Guang Liu, Lin Liu, Qiang-Min Huang, Thi-Tham Nguyen, Yan-Tao Ma, Jia-Min Zha. Decreased Spontaneous Electrical Activity and Acetylcholine at Myofascial Trigger Spots after Dry Needling Treatment: A Pilot Study. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-09-29. PMID:28592980. |
the aims of this study are to investigate the changes in spontaneous electrical activities (seas) and in acetylcholine (ach), acetylcholine receptor (achr), and acetylcholine esterase (ache) levels after dry needling at myofascial trigger spots in model rats. |
2020-09-29 |
2023-08-13 |
rat |
| Rohit Pardeshi, Nityanand Bolshette, Kundlik Gadhave, Mohammad Arfeen, Sahabuddin Ahmed, Rohitash Jamwal, Bruce D Hammock, Mangala Lahkar, Sumanta Kumar Goswam. Docosahexaenoic Acid Increases the Potency of Soluble Epoxide Hydrolase Inhibitor in Alleviating Streptozotocin-Induced Alzheimer's Disease-Like Complications of Diabetes. Frontiers in pharmacology. vol 10. 2020-09-28. PMID:31068802. |
the activity of acetylcholinesterase (ache) which metabolizes acetylcholine was increased in the brain of diabetic rats. |
2020-09-28 |
2023-08-13 |
rat |
| Qing-Guang Liu, Qiang-Min Huang, Lin Liu, Thi-Tham Nguye. Structural and functional abnormalities of motor endplates in rat skeletal model of myofascial trigger spots. Neuroscience letters. vol 711. 2020-09-28. PMID:31398457. |
c1 and m1 were used for acetylcholine (ach) content measurement, while c2 and m2 were utilized for acetylcholinesterase (ache) staining. |
2020-09-28 |
2023-08-13 |
human |
| Ming-Yang Liu, Fan Zeng, Yue Shen, Yu-Ying Wang, Ning Zhang, Fang Gen. Bioguided Isolation and Structure Identification of Acetylcholinesterase Enzyme Inhibitors from Drynariae Rhizome. Journal of analytical methods in chemistry. vol 2020. 2020-09-28. PMID:32185082. |
here, a high-throughput assay monitoring the transformation of iodized choline from iodized acetylcholine catalyzed by ache was established based on uplc-ms/ms. |
2020-09-28 |
2023-08-13 |
Not clear |
| Yameng Han, Zhongju Ye, Fuyan Wang, Tianyu Chen, Lin Wei, Langxing Chen, Lehui Xia. Single-particle enumeration-based ultrasensitive enzyme activity quantification with fluorescent polymer nanoparticles. Nanoscale. vol 11. issue 31. 2020-09-11. PMID:31353389. |
acetylcholinesterase (ache) plays a vital role in nerve conduction through rapidly hydrolyzing the neurotransmitter acetylcholine (ach) and is correlated with alzheimer's disease. |
2020-09-11 |
2023-08-13 |
human |
| Rui Jin, Zihao Xing, Deshuai Kong, Xu Yan, Fangmeng Liu, Yuan Gao, Peng Sun, Xishuang Liang, Geyu L. Sensitive colorimetric sensor for point-of-care detection of acetylcholinesterase using cobalt oxyhydroxide nanoflakes. Journal of materials chemistry. B. vol 7. issue 8. 2020-07-23. PMID:32255162. |
in this sensor, ache catalytically hydrolyzed acetylcholine (ach) to produce choline, which was further efficiently oxidized by cho to yield h |
2020-07-23 |
2023-08-13 |
Not clear |
| Xuzhi Li, Meie Wang, Rong Jiang, Liping Zheng, Weiping Che. Evaluation of joint toxicity of heavy metals and herbicide mixtures in soils to earthworms (Eisenia fetida). Journal of environmental sciences (China). vol 94. 2020-07-10. PMID:32563477. |
the responses of multiple biomarkers, including the activities of catalase (cat), superoxide dismutase (sod), glutathione reductase (gr) and acetylcholine esterase (ache), the concentrations of glycogen, soluble protein (sp), malonaldehyde (mda), and metallothionein (mt), and the neutral red uptake test (nru), were investigated. |
2020-07-10 |
2023-08-13 |
cat |
| Huan Xu, Lingke Chen, Xiao Zhang, Xuliang Jiang, Weitian Tian, Weifeng Yu, Xiangrui Wang, Jie Tian, Diansan S. Central cholinergic neuronal degeneration promotes the development of postoperative cognitive dysfunction. Laboratory investigation; a journal of technical methods and pathology. vol 99. issue 7. 2020-06-25. PMID:30626892. |
the impact of anesthesia/surgery (appendectomy) on learning and memory and the levels of choline acetyltransferase (chat), acetylcholinesterase (ache), vesicular acetylcholine transporter (vacht), and choline transporter (cht) in adult and aged mice were measured. |
2020-06-25 |
2023-08-13 |
mouse |
| Gonzalo E Fenoy, Waldemar A Marmisollé, Omar Azzaroni, Wolfgang Knol. Acetylcholine biosensor based on the electrochemical functionalization of graphene field-effect transistors. Biosensors & bioelectronics. vol 148. 2020-06-18. PMID:31665672. |
we present a new strategy of acetylcholinesterease (ache) immobilization on graphene field-effect transistors (gfets) for building up acetylcholine sensors. |
2020-06-18 |
2023-08-13 |
Not clear |
| Cuneyt Caglayan, Yeliz Demir, Sefa Kucukler, Parham Taslimi, Fatih Mehmet Kandemir, İlhami Gulçi. The effects of hesperidin on sodium arsenite-induced different organ toxicity in rats on metabolic enzymes as antidiabetic and anticholinergics potentials: A biochemical approach. Journal of food biochemistry. vol 43. issue 2. 2020-06-12. PMID:31353640. |
in our work, it was purposed to investigate the effects of sodium arsenite (sa) and hesperidin (hsp) administered to rats on some metabolic enzymes including carbonic anhydrase (ca), aldose reductase (ar), paraoxonase-1 (pon1), α-glycosidase (α-gly), butyrylcholine esterase (bche), acetylcholine esterase (ache) enzymes activities in the brain, heart, liver, testis, and kidney tissues of rats. |
2020-06-12 |
2023-08-13 |
human |
| Cristina Romero Rocamora, Kalavathy Ramasamy, Siong Meng Lim, Abu Bakar Abdul Majeed, Snezana Agatonovic-Kustri. HPTLC based approach for bioassay-guided evaluation of antidiabetic and neuroprotective effects of eight essential oils of the Lamiaceae family plants. Journal of pharmaceutical and biomedical analysis. vol 178. 2020-06-04. PMID:31618702. |
hptlc hyphenated with microchemical (dpph•, p-anisaldehyde, and ferric chloride) derivatizations, was used to evaluate antioxidant activity, presence of phytosterols and terpenoids, and polyphenolic content, while the combination with biochemical (α-amylase and acetylcholine esterase (ache) enzymatic) derivatizations was used to asses α-amylase and ache inhibitory activities. |
2020-06-04 |
2023-08-13 |
Not clear |
| Peng Zhang, Caixia Fu, Yuzhe Xiao, Qian Zhang, Caifeng Din. Copper(II) complex as a turn on fluorescent sensing platform for acetylcholinesterase activity with high sensitivity. Talanta. vol 208. 2020-06-04. PMID:31816742. |
a "turn on" fluorometric assay is described herein for ache activity detection, according to the specific enzyme catalyzed reaction of acetylcholine (atch) by ache, which generates thiocholine (tch) as the product. |
2020-06-04 |
2023-08-13 |
Not clear |
| Hua Fang, Hua-Feng Li, Miao Yang, Ren Liao, Ru-Rong Wang, Quan-Yun Wang, Peng-Cheng Zheng, Fang-Xiang Zhang, Jian-Ping Zhan. NF-κB signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via RCAN1 in neonatal rats with hypoxic-ischemic brain damage. Cell cycle (Georgetown, Tex.). vol 18. issue 9. 2020-05-27. PMID:30990350. |
expression of rcan1, nf-κb signaling pathway-related genes and glial fibrillary acidic protein (gfap), s-100β and acetylcholine (ach) level, and acetylcholinesterase (ache) activity were determined with neuron apoptosis detected to further explore the function of nf-κb signaling pathway. |
2020-05-27 |
2023-08-13 |
rat |
| Sahar Fanoudi, Mohaddeseh S Alavi, Mahmoud Hosseini, Hamid R Sadeghni. Nigella sativa and thymoquinone attenuate oxidative stress and cognitive impairment following cerebral hypoperfusion in rats. Metabolic brain disease. vol 34. issue 4. 2020-04-30. PMID:31016464. |
in the present study, we investigated the effect of hydroalcoholic extract of n. sativa seeds (nse) and its active constituent, thymoquinone (tq), on learning and memory deficits, hippocampal acetylcholine esterase (ache) activity, and markers of redox status, mainly lipid peroxidation and superoxide dismutase (sod) activity following cerebral hypoperfusion in rats. |
2020-04-30 |
2023-08-13 |
rat |
| Azime Berna Özçelik, Zeynep Özdemir, Suat Sari, Semra Utku, Mehtap Uysa. A new series of pyridazinone derivatives as cholinesterases inhibitors: Synthesis, in vitro activity and molecular modeling studies. Pharmacological reports : PR. vol 71. issue 6. 2020-04-27. PMID:31675671. |
acetylcholinesterase (ache) and butyrylcholinesterase (bche) are known to be serine hydrolase enzymes responsible for the hydrolysis of acetylcholine (ach). |
2020-04-27 |
2023-08-13 |
Not clear |
| Christoph Fenzl, Christa Genslein, Alexander Zöpfl, Antje J Baeumner, Thomas Hirsc. A photonic crystal based sensing scheme for acetylcholine and acetylcholinesterase inhibitors. Journal of materials chemistry. B. vol 3. issue 10. 2020-04-08. PMID:32262377. |
we demonstrate this unique combination by successfully detecting acetylcholine (ach) and acetylcholinesterase (ache) inhibitors. |
2020-04-08 |
2023-08-13 |
human |
| Li Su, Xinai Yu, Wenjie Qin, Wenpei Dong, Chengke Wu, Yan Zhang, Guojiang Mao, Suling Fen. One-step analysis of glucose and acetylcholine in water based on the intrinsic peroxidase-like activity of Ni/Co LDHs microspheres. Journal of materials chemistry. B. vol 5. issue 1. 2020-04-08. PMID:32263440. |
we also extended the one-step method to detect acetylcholine (ach) by taking advantage of the specific catalytic reaction of acetylcholinesterase (ache) and choline oxidase (chox). |
2020-04-08 |
2023-08-13 |
Not clear |