| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W Yao, D A Godfre. Choline acetyltransferase in cochlear root neurons. Hearing research. vol 69. issue 1-2. 1993-12-17. PMID:8226351. |
some of our preparations showed immunoreactivity of somata of cochlear root neurons with both polyclonal and monoclonal antibodies against choline acetyltransferase (chat) which, despite their very weak histochemical reaction for acetylcholinesterase (ache), suggested that cochlear root neurons might be cholinergic. |
1993-12-17 |
2023-08-12 |
rat |
| D L Bellinger, D Lorton, R W Hamill, S Y Felten, D L Felte. Acetylcholinesterase staining and choline acetyltransferase activity in the young adult rat spleen: lack of evidence for cholinergic innervation. Brain, behavior, and immunity. vol 7. issue 3. 1993-12-10. PMID:8219410. |
collectively, the overlapping distribution of ache+ and na nerve profiles in spleen and parallel loss of both population of nerve fibers following surgical and chemical sympathectomy support the presence of ache in na nerves colocalized with norepinephrine, and thus make ache+ staining an inappropriate marker for cholinergic innervation in the rat spleen. |
1993-12-10 |
2023-08-12 |
rat |
| F Amenta, F Franch, A Ricci, J A Veg. Cholinergic neurotransmission in the hippocampus of aged rats: influence of L-alpha-glycerylphosphorylcholine treatment. Annals of the New York Academy of Sciences. vol 695. 1993-12-10. PMID:8239302. |
the influence of aging and of l-alpha-glycerylphosphorylcholine (gfc) treatment on the acetylcholine synthesizing and degradating enzymes choline acetyltransferase (chat) and acetylcholinesterase (ache) and on cholinergic muscarinic m-1 and m-2 receptors were assessed in the hippocampus using immunocytochemical, histochemical and radioligand binding techniques, respectively. |
1993-12-10 |
2023-08-12 |
rat |
| Z Malatová, J Marsal. Cholinergic enzymes in spinal cord infarction. Biochemical and histochemical changes. Molecular and chemical neuropathology. vol 19. issue 3. 1993-11-18. PMID:8397588. |
there was a relatively greater decrease in chat and ache activities in the ventral horns that corresponded with a more prominent morphological damage of the cholinergic neurons in this zone of the spinal cord. |
1993-11-18 |
2023-08-12 |
rabbit |
| F Dajas, R Silveira, G Costa, M E Castello, D Jerusalinsky, J Medina, D Levesque, S Greenfiel. Differential cholinergic and non-cholinergic actions of acetylcholinesterase in the substantia nigra revealed by fasciculin-induced inhibition. Brain research. vol 616. issue 1-2. 1993-09-30. PMID:7689409. |
in addition, treatment with fas in the substantia nigra also reveals the possible existence of at least two distinct pools of ache with, respectively, non-cholinergic and cholinergic actions. |
1993-09-30 |
2023-08-12 |
rat |
| E K Perry, J A Court, M Johnson, C J Smith, V James, A V Cheng, J M Kerwin, C M Morris, M A Piggott, J A Edwardso. Autoradiographic comparison of cholinergic and other transmitter receptors in the normal human hippocampus. Hippocampus. vol 3. issue 3. 1993-09-22. PMID:8394772. |
the regional distribution of cholinergic innervation to the normal adult human hippocampus and adjacent cortex, marked by acetylcholinesterase (ache) fiber and terminal reactivity, is notable for its concentration in ca2/3 of ammon's horn and the dentate fascia. |
1993-09-22 |
2023-08-12 |
human |
| K Tanaka, T Tamura, M Kawashima, S Ueda, Y Matsumoto, M Kawata, Y Ogino, T Yamamoto, H Honjo, H Okad. [The histochemical study of the effects of estrogen on the forebrain cholinergic neurons of fetal female rats transplanted into the anterior eye chamber of adult female rats]. Nihon Naibunpi Gakkai zasshi. vol 69. issue 5. 1993-08-18. PMID:8330655. |
some host rats were treated with 2mg estradiol valerate (e2v) injected every 3 days after ovariectomy while others were not 2 and 4 weeks after transplantation, the growth of cholinergic neurons in the graft was studied using acethylcholinesterase (ache) histochemistry. |
1993-08-18 |
2023-08-12 |
rat |
| O Stewar. Signals that induce sprouting in the central nervous system: sprouting is delayed in a strain of mouse exhibiting delayed axonal degeneration. Experimental neurology. vol 118. issue 3. 1993-08-06. PMID:1284863. |
cholinergic sprouting was then evaluated using a histochemical technique for acetylcholinesterase (ache) in mutant mice and normal controls. |
1993-08-06 |
2023-08-11 |
mouse |
| J Nio, M J Besson, P Breto. Ontogenic distribution of muscarinic receptors and acetylcholinesterase in the rabbit hippocampus. Brain research bulletin. vol 31. issue 6. 1993-07-29. PMID:8518962. |
this study shows a differential developmental evolution in the distribution of ache and muscarinic m1 receptors, and no obvious correspondence between these two cholinergic markers was observed. |
1993-07-29 |
2023-08-12 |
rabbit |
| J S Kahle, J Ułas, C W Cotma. Increased sensitivity to adenosine in the rat dentate gyrus molecular layer two weeks after partial entorhinal lesions. Brain research. vol 609. issue 1-2. 1993-07-15. PMID:8508304. |
ache histochemistry performed after recording revealed dense staining in the dentate gyrus molecular layer of post-lesion slices as compared to slices from unlesioned animals, confirming that sprouting of cholinergic fibers occurred as expected from previous entorhinal lesion studies. |
1993-07-15 |
2023-08-12 |
rat |
| R J Richardson, T B Moore, U S Kayyali, J H Fowke, J C Randal. Inhibition of hen brain acetylcholinesterase and neurotoxic esterase by chlorpyrifos in vivo and kinetics of inhibition by chlorpyrifos oxon in vitro: application to assessment of neuropathic risk. Fundamental and applied toxicology : official journal of the Society of Toxicology. vol 20. issue 3. 1993-07-08. PMID:7684990. |
previous work has shown that the ability of op insecticides to cause acute cholinergic toxicity versus opidn can be predicted from their relative tendency to inhibit the intended target, acetylcholinesterase (ache), versus the putative neuropathic target, nte, in brain tissue. |
1993-07-08 |
2023-08-12 |
human |
| T Arendt, M K Brückner, M Lange, V Big. Changes in acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease resemble embryonic development--a study of molecular forms. Neurochemistry international. vol 21. issue 3. 1993-06-24. PMID:1303164. |
the pattern of molecular forms of acetylcholinesterase (ache, ec 3.1.1.7) and butyrylcholinesterase (bche, ec 3.1.1.8) separated by density gradient centrifugation was investigated in the brain and cerebrospinal fluid in alzheimer's disease (ad), in human embryonic brain and in rat brain after experimental cholinergic deafferentation of the cerebral cortex. |
1993-06-24 |
2023-08-11 |
human |
| T Arendt, M K Brückner, M Lange, V Big. Changes in acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease resemble embryonic development--a study of molecular forms. Neurochemistry international. vol 21. issue 3. 1993-06-24. PMID:1303164. |
a similar decrease of the ache g4 form as observed in ad can be induced in rat by experimental cholinergic deafferentation of the cerebral cortex. |
1993-06-24 |
2023-08-11 |
human |
| T Arendt, M K Brückner, M Lange, V Big. Changes in acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease resemble embryonic development--a study of molecular forms. Neurochemistry international. vol 21. issue 3. 1993-06-24. PMID:1303164. |
it is, therefore, concluded that the degeneration of the cholinergic cortical afferentation in ad as reflected by a decrease of ache g4 is accompanied by the process of a neuritic sprouting response involved in plaque formation which is probably associated with the expression of a developmental form of the enzyme. |
1993-06-24 |
2023-08-11 |
human |
| M Wójcik, A Bidziński, M Slósarska, S Puzyńsk. [Psychophysiological characteristics and metabolic indices of neurotransmitter metabolism in patients ill with endogenous depression]. Psychiatria polska. vol 26. issue 3-4. 1993-06-03. PMID:1301598. |
the investigation considered the interrelationship between psychophysiological parameters (heart rate, respiration rhythm, postural muscular tension) and the indices of the cholinergic and adrenergic systems (kinetic parameters of choline transport in the blood; vmax, the activity of plasmic pseudocholinesterase, che; blood acetylcholinesterase ache, monoaminoxidase in blood platelets, mao; and dopamine beta hydroxylase dbh). |
1993-06-03 |
2023-08-11 |
Not clear |
| Z F Chen, J T Ma, Z M Ni, Z W M. [Guiding effect of embryonic fimbria graft on cholinergic fiber growth in hippocampus of adult rats]. Sheng li xue bao : [Acta physiologica Sinica]. vol 44. issue 4. 1993-04-05. PMID:1293750. |
two weeks later, the grafts were examined for cholinergic fibers with ache histochemical method. |
1993-04-05 |
2023-08-11 |
rat |
| M E Appleyar. Secreted acetylcholinesterase: non-classical aspects of a classical enzyme. Trends in neurosciences. vol 15. issue 12. 1993-02-11. PMID:1282748. |
recent evidence suggests that termination of cholinergic transmission is just one of the many ways in which acetylcholinesterase (ache) could influence neuronal function. |
1993-02-11 |
2023-08-11 |
Not clear |
| R C Gupta, W D Dettbar. Potential of memantine, D-tubocurarine, and atropine in preventing acute toxic myopathy induced by organophosphate nerve agents: soman, sarin, tabun and VX. Neurotoxicology. vol 13. issue 3. 1993-02-03. PMID:1475066. |
pretreatment with memantine hcl (mem, 18 mg/kg, sc) together with atropine sulfate (ats, 16 mg/kg, sc), 60 min and 15 min, respectively, prior to nerve agents attenuated ache inhibition, prevented myonecrosis, and muscle fasciculations as well as other signs of cholinergic toxicity. |
1993-02-03 |
2023-08-11 |
rat |
| P L Di Patre, C W Mathes, L L Butche. Differential visualization of cholinesterasic neuronal somata and fibers by use of modifications of acetylcholinesterase pharmacohistochemistry. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 41. issue 1. 1993-01-28. PMID:7678024. |
we modified existing acetylcholinesterase (ache) histochemical techniques to visualize cholinergic neuronal somata and processes in the same rat brain. |
1993-01-28 |
2023-08-12 |
rat |
| M E Appleyard, B McDonal. Acetylcholinesterase and butyrylcholinesterase activities in cerebrospinal fluid from different levels of the neuraxis of patients with dementia of the Alzheimer type. Journal of neurology, neurosurgery, and psychiatry. vol 55. issue 11. 1993-01-26. PMID:1469405. |
such altered secretion of ache in the brain could have profound implications not only for cholinergic transmission in these patients but also for the proposed noncholinergic modulatory actions of ache. |
1993-01-26 |
2023-08-11 |
Not clear |