| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Ikeda, J Yamashita, T Egashira, F Takayama, Y Yamanak. [Study on the anti-dementia therapies for rats with a unilateral basal forebrain lesion--serial changes of the cholinergic markers' activities and event-related potentials after the administration of bifemelane hydrochloride or autotransplantation of the vagal nodosal ganglion]. No to shinkei = Brain and nerve. vol 47. issue 5. 1995-07-24. PMID:7786622. |
these results might indicate as follows: 1) compensatory postsynaptic process such as cortical machr increase and ache decrease occurred after acute cholinergic depletion. |
1995-07-24 |
2023-08-12 |
rat |
| K Ikeda, J Yamashita, T Egashira, F Takayama, Y Yamanak. [Study on the anti-dementia therapies for rats with a unilateral basal forebrain lesion--serial changes of the cholinergic markers' activities and event-related potentials after the administration of bifemelane hydrochloride or autotransplantation of the vagal nodosal ganglion]. No to shinkei = Brain and nerve. vol 47. issue 5. 1995-07-24. PMID:7786622. |
2) administration of bif and x autotransplantation recovered cortical cat and ache levels and normalized cholinergic neuronal activity of p300. |
1995-07-24 |
2023-08-12 |
rat |
| J B Hutchins, J M Bernanke, V E Jefferso. Acetylcholinesterase in the developing ferret retina. Experimental eye research. vol 60. issue 2. 1995-07-14. PMID:7781740. |
the function of acetylcholinesterase (ache) is to terminate the action of acetylcholine at the cholinergic synapse. |
1995-07-14 |
2023-08-12 |
Not clear |
| C V Borlongan, T K Koutouzis, T S Randall, T B Freeman, D W Cahill, P R Sanber. Systemic 3-nitropropionic acid: behavioral deficits and striatal damage in adult rats. Brain research bulletin. vol 36. issue 6. 1995-06-29. PMID:7538873. |
results revealed striatal glial infiltration, loss of intrinsic striatal cholinergic neurons, but some sparing of large ache positive neurons, minimal damage of nadph-diaphorase-containing neurons, and very slight, if any, alterations in cytochrome oxidase activity. |
1995-06-29 |
2023-08-12 |
rat |
| W F Li, C E Furlong, L G Cost. Paraoxonase protects against chlorpyrifos toxicity in mice. Toxicology letters. vol 76. issue 3. 1995-06-27. PMID:7539166. |
administration of paraoxonase 30 min after this exposure abolished cholinergic signs and significantly protected against ache inhibition. |
1995-06-27 |
2023-08-12 |
mouse |
| B Buwalda, L de Groote, E A Van der Zee, T Matsuyama, P G Luite. Immunocytochemical demonstration of developmental distribution of muscarinic acetylcholine receptors in rat parietal cortex. Brain research. Developmental brain research. vol 84. issue 2. 1995-06-14. PMID:7743637. |
the development of m35-ir in the cortex appeared to antedate that of its cholinergic afferentation as indicated by ache histochemical study. |
1995-06-14 |
2023-08-12 |
rat |
| H Kobayashi, Y Wang, H Hirakawa, D S O'Briain, P Pur. Intraoperative evaluation of extent of aganglionosis by a rapid acetylcholinesterase histochemical technique. Journal of pediatric surgery. vol 30. issue 2. 1995-06-07. PMID:7738746. |
using a supplemental oxidation step, the authors modified the acetylcholinesterase (ache) histochemistry technique of karnovsky and roots to produce staining of cholinergic nerve fibers in 10 minutes rather than in 2 hours, as required with the conventional ache technique. |
1995-06-07 |
2023-08-12 |
Not clear |
| S Rossner, R Schliebs, V Big. Ibotenic acid lesion of nucleus basalis magnocellularis differentially affects cholinergic, glutamatergic and GABAergic markers in cortical rat brain regions. Brain research. vol 668. issue 1-2. 1995-05-10. PMID:7704621. |
in cortical regions displaying a reduced activity of ache and decreased levels of high-affinity choline uptake sites due to forebrain cholinergic lesion, nmda receptor binding was markedly reduced in comparison to the unlesioned brain side whereas ampa and kainate binding has been significantly increased in these regions. |
1995-05-10 |
2023-08-12 |
rat |
| H Namba, T Irie, K Fukushi, M Iy. In vivo measurement of acetylcholinesterase activity in the brain with a radioactive acetylcholine analog. Brain research. vol 667. issue 2. 1995-05-03. PMID:7697367. |
the method would be applicable for in vivo studies of human brain ache activity in disorders of central cholinergic systems such as alzheimer's disease. |
1995-05-03 |
2023-08-12 |
human |
| T W Farris, L L Butcher, J D Oh, N J Wool. Trophic-factor modulation of cortical acetylcholinesterase reappearance following transection of the medial cholinergic pathway in the adult rat. Experimental neurology. vol 131. issue 2. 1995-04-27. PMID:7895819. |
laminar patterns of cortical acetylcholinesterase (ache) activity are reestablished in the adult, pharmacologically unmanipulated rat following axotomy of the medial cholinergic pathway. |
1995-04-27 |
2023-08-12 |
rat |
| K Tanaka, N Ogawa, M Asanuma, Y Kondo, A Mor. Chronic administration of acetylcholinesterase inhibitor in the senescent rat brain. Neurobiology of aging. vol 15. issue 6. 1995-04-18. PMID:7891827. |
the effects of chronic administration of ena-713, an acetylcholinesterase (ache) inhibitor, on pre- and postsynaptic cholinergic indices were examined in the senescent rat brain. |
1995-04-18 |
2023-08-12 |
rat |
| M Weinstock, M Razin, M Chorev, A En. Pharmacological evaluation of phenyl-carbamates as CNS-selective acetylcholinesterase inhibitors. Journal of neural transmission. Supplementum. vol 43. 1995-04-13. PMID:7884403. |
sdz ena 713 produced a 10-fold greater inhibition of ache in the hippocampus and cortex than in the heart and skeletal muscle, which explains its relatively low toxicity and freedom from cholinergic side effects. |
1995-04-13 |
2023-08-12 |
human |
| Y Ishii, J Kojima, N Ikeda, K Kawashim. Effect of NIK-247 on basal concentrations of extracellular acetylcholine in the cerebral cortex of conscious, freely moving rats. Japanese journal of pharmacology. vol 66. issue 3. 1995-03-30. PMID:7869615. |
these findings demonstrate that nik-247 increases extracellular ach concentration and inhibits ache activity in the cerebral cortex after oral administration, and they suggest that nik-247 facilitates central cholinergic transmission. |
1995-03-30 |
2023-08-12 |
rat |
| F Yufu, T Egashira, Y Yamanak. Age-related changes of cholinergic markers in the rat brain. Japanese journal of pharmacology. vol 66. issue 2. 1995-03-29. PMID:7869609. |
to evaluate whether any degenerative changes affect the brain cholinergic systems during natural aging, we compared various cholinergic biochemical markers (number of muscarinic receptors, machr; choline acetyltransferase activity, chat; acetylcholinesterase activity, ache; and sodium-dependent high affinity choline uptake) in the cortical (cr) and subcortical (ss) regions of the brains of aged (24 month) and young (2 month) rats. |
1995-03-29 |
2023-08-12 |
rat |
| I A Alonso, J C Prieto, E Arill. Effect of acute and chronic diisopropylfluorophosphate and atropine administration on somatostatin binding in the rat frontoparietal cortex and hippocampus. Psychopharmacology. vol 110. issue 1-2. 1995-03-29. PMID:7870867. |
the acute and chronic administration of diisopropylfluorophosphate (dfp), an inhibitor of acetylcholinesterase (ache), and of atropine, a blocker of muscarinic cholinergic receptors, did not affect somatostatin-like immunoreactivity (sli) content in the frontoparietal cortex and hippocampus of rats. |
1995-03-29 |
2023-08-12 |
rat |
| R J Richardso. Assessment of the neurotoxic potential of chlorpyrifos relative to other organophosphorus compounds: a critical review of the literature. Journal of toxicology and environmental health. vol 44. issue 2. 1995-03-16. PMID:7531775. |
because chlorpyrifos and other op insecticides are designed to produce acute cholinergic effects through inhibition of acetylcholinesterase (ache) and some op compounds can cause op compound-induced delayed neurotoxicity (opidn) via chemical modification of neurotoxic esterase (neuropathy target esterase, nte), this review focuses on the capacity of chlorpyrifos to precipitate these and other adverse neurological consequences. |
1995-03-16 |
2023-08-12 |
rat |
| Y Dimberg, L Lärkfor. Effects of irradiation on cholinergic neurons and nerve growth factor mRNA in mouse foetal brain aggregation cultures. International journal of radiation biology. vol 66. issue 6. 1995-02-06. PMID:7814978. |
the level of a neuronal marker for cholinergic neurons, namely acetylcholine esterase (ache), increased linearly with the dose of irradiation after 10 days in vitro. |
1995-02-06 |
2023-08-12 |
mouse |
| Y Dimberg, L Lärkfor. Effects of irradiation on cholinergic neurons and nerve growth factor mRNA in mouse foetal brain aggregation cultures. International journal of radiation biology. vol 66. issue 6. 1995-02-06. PMID:7814978. |
thus, we showed that cholinergic and morphological markers are affected by irradiation and the alteration in ache activity induced by irradiation correlated well with the changes in ngf mrna. |
1995-02-06 |
2023-08-12 |
mouse |
| D Rodríguez-Ithurralde, O Vincen. Excitotoxicity and cholinergic chemical markers during programmed motor neurone death. Journal of the neurological sciences. vol 124 Suppl. 1995-02-02. PMID:7807141. |
we measured cholinergic markers and acetylcholinesterase (ache) molecular forms after glutamate receptor stimulation of superfused slices of mouse spinal cord at different developmental ages. |
1995-02-02 |
2023-08-12 |
mouse |
| J De Bleecker, D Lison, K Van Den Abeele, J Willems, J De Reuc. Acute and subacute organophosphate poisoning in the rat. Neurotoxicology. vol 15. issue 2. 1995-01-12. PMID:7991223. |
marked differences are noted in the duration of cholinergic symptoms and of ache inhibition after either paraoxon and mipafox, or fenthion poisoning. |
1995-01-12 |
2023-08-12 |
rat |