| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Kása, Z Rakonczay, K Guly. The cholinergic system in Alzheimer's disease. Progress in neurobiology. vol 52. issue 6. 1997-11-05. PMID:9316159. |
the results demonstrate a great variation in the distribution of acetylcholinesterase, choline acetyltransferase, and the nicotinic and muscarinic acetylcholine receptors in the different brain areas, nuclei and subnuclei. |
1997-11-05 |
2023-08-12 |
Not clear |
| A Alvarez, C Opazo, R Alarcón, J Garrido, N C Inestros. Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils. Journal of molecular biology. vol 272. issue 3. 1997-10-28. PMID:9325095. |
acetylcholinesterase (ache), an enzyme involved in the hydrolysis of the neurotransmitter acetylcholine, consistently colocalizes with the amyloid deposits characteristic of alzheimer's disease and may contribute to the generation of amyloid proteins and/or physically affect fibril assembly. |
1997-10-28 |
2023-08-12 |
Not clear |
| R A Giniatullin, M Talantova, F Vyskoci. Desensitization shortens the high-quantal-content endplate current time course in frog muscle with intact cholinesterase. The Journal of physiology. vol 502 ( Pt 3). 1997-10-27. PMID:9279814. |
the desensitization induced by bath-applied carbachol or acetylcholine (ach) and potentiated by proadifen (skf 525a) was studied in the frog sartorius with intact synaptic acetylcholinesterase (ache). |
1997-10-27 |
2023-08-12 |
Not clear |
| C Koenigsberger, S Chiappa, S Brimijoi. Neurite differentiation is modulated in neuroblastoma cells engineered for altered acetylcholinesterase expression. Journal of neurochemistry. vol 69. issue 4. 1997-10-27. PMID:9326267. |
previous observations from several groups suggest that acetylcholinesterase (ache) may have a role in neural morphogenesis, but not solely by virtue of its ability to hydrolyze acetylcholine. |
1997-10-27 |
2023-08-12 |
Not clear |
| M Pfaffendorf, T A Bruning, H D Batnik, P A van Zwiete. The interaction between methylene blue and the cholinergic system. British journal of pharmacology. vol 122. issue 1. 1997-10-23. PMID:9298533. |
human plasma from young healthy male volunteers, purified human pseudocholinesterase and purified bovine true acetylcholinesterase were incubated with acetylcholine and increasing concentrations of mb (0.1-100 mumol l-1) in the presence of the ph-indicator m-nitrophenol for 30 min at 25 degrees c. the amount of acetic acid produced by the enzymatic hydrolysis of acetylcholine was determined photometrically. |
1997-10-23 |
2023-08-12 |
human |
| T Irie, K Fukushi, Y Akimoto, H Tamagami, T Nozak. Design and evaluation of radioactive acetylcholine analogs for mapping brain acetylcholinesterase (AchE) in vivo. Nuclear medicine and biology. vol 21. issue 6. 1997-09-25. PMID:9234329. |
design and evaluation of radioactive acetylcholine analogs for mapping brain acetylcholinesterase (ache) in vivo. |
1997-09-25 |
2023-08-12 |
mouse |
| T Irie, K Fukushi, Y Akimoto, H Tamagami, T Nozak. Design and evaluation of radioactive acetylcholine analogs for mapping brain acetylcholinesterase (AchE) in vivo. Nuclear medicine and biology. vol 21. issue 6. 1997-09-25. PMID:9234329. |
for mapping brain acetylcholinesterase (ache) in vivo, seven radioactive acetylcholine analogs, n-[14c]methylpiperidyl-3- and 4-acetates, propionates, isobutyrates, and 3-butyrate were newly synthesized and evaluated in mice. |
1997-09-25 |
2023-08-12 |
mouse |
| M Iyo, H Namba, K Fukushi, H Shinotoh, S Nagatsuka, T Suhara, Y Sudo, K Suzuki, T Iri. Measurement of acetylcholinesterase by positron emission tomography in the brains of healthy controls and patients with Alzheimer's disease. Lancet (London, England). vol 349. issue 9068. 1997-09-15. PMID:9269216. |
we have shown regional acetylcholinesterase activity in vivo in rodent and primate brains with radioactive acetylcholine analogues. |
1997-09-15 |
2023-08-12 |
Not clear |
| C Bhattacharya, R N Singh, S Misra, S Rathau. Diethylcarbamazine: effect on lysosomal enzymes and acetylcholine in Wuchereria bancrofti infection. Tropical medicine & international health : TM & IH. vol 2. issue 7. 1997-09-11. PMID:9270736. |
it is proposed that parasites secrete acetylcholinesterase in the circulation which degrades acetylcholine. |
1997-09-11 |
2023-08-12 |
human |
| M Suzuki, N Kishibayashi, T Yokoyama, A Karasaw. Effect of KW-5092, novel gastroprokinetic agent, on the peristalsis in the isolated guinea pig ileum. Japanese journal of pharmacology. vol 74. issue 1. 1997-08-05. PMID:9195302. |
we examined the effect of kw-5092, a gastroprokinetic agent with acetylcholinesterase inhibitory and acetylcholine release facilitatory activities, on the peristalsis of isolated guinea pig ileum. |
1997-08-05 |
2023-08-12 |
Not clear |
| D N Zhu, G Z Xie, P L. The cardiovascular response to medullary cholinergic and corticoid stimulation is calcium channel dependent in rats. Blood pressure. vol 6. issue 3. 1997-07-29. PMID:9181256. |
microinjection of an acetylcholinesterase inhibitor physostigmine (0.4 microgram/0.1 microliter/site) or acetylcholine (ach, 25 ng/0.1 microliter/site) into the rostral ventrolateral medulla (rvlm) caused an increase in blood pressure (bp), heart rate (hr) and the pressor response produced by stimulation of the dorsal periaqueductal grey (dpag) in the midbrain. |
1997-07-29 |
2023-08-12 |
rat |
| S Yamada, T Fujii, K Kawashim. Oral administration of KW-5092, a novel gastroprokinetic agent with acetylcholinesterase inhibitory and acetylcholine release enhancing activities, causes a dose-dependent increase in the blood acetylcholine content of beagle dogs. Neuroscience letters. vol 225. issue 1. 1997-07-24. PMID:9143009. |
oral administration of kw-5092, a novel gastroprokinetic agent with acetylcholinesterase inhibitory and acetylcholine release enhancing activities, causes a dose-dependent increase in the blood acetylcholine content of beagle dogs. |
1997-07-24 |
2023-08-12 |
Not clear |
| R Bowser, J H Kordower, E J Mufso. A confocal microscopic analysis of galaninergic hyperinnervation of cholinergic basal forebrain neurons in Alzheimer's disease. Brain pathology (Zurich, Switzerland). vol 7. issue 2. 1997-07-17. PMID:9161723. |
we propose that therapies based solely on acetylcholinesterase inhibitors may be insufficient to effectively increase cortical levels of acetylcholine. |
1997-07-17 |
2023-08-12 |
Not clear |
| M D Krasowski, D S McGehee, J Mos. Natural inhibitors of cholinesterases: implications for adverse drug reactions. Canadian journal of anaesthesia = Journal canadien d'anesthesie. vol 44. issue 5 Pt 1. 1997-07-14. PMID:9161749. |
acetylcholinesterase and butyrylcholinesterase are two closely related enzymes important in the metabolism of acetylcholine and anaesthetic drugs, including succinylcholine, mivacurium, and cocaine. |
1997-07-14 |
2023-08-12 |
Not clear |
| K Matsuno, T Senda, T Kobayashi, K Okamoto, K Nakata, S Mit. SA4503, a novel cognitive enhancer, with sigma 1 receptor agonistic properties. Behavioural brain research. vol 83. issue 1-2. 1997-07-09. PMID:9062689. |
on the other hand, tetrahydroaminoacridine (tha), an acetylcholinesterase (ache) inhibitor, increased the extracellular acetylcholine level in both regions. |
1997-07-09 |
2023-08-12 |
rat |
| K L Yuknavage, R A Fenske, D A Kalman, M C Keifer, C E Furlon. Simulated dermal contamination with capillary samples and field cholinesterase biomonitoring. Journal of toxicology and environmental health. vol 51. issue 1. 1997-06-19. PMID:9169060. |
ops inhibit acetylcholinesterase, the enzyme responsible for breaking down the neurotransmitter acetylcholine. |
1997-06-19 |
2023-08-12 |
human |
| M Srivatsan, B Peret. Acetylcholinesterase promotes regeneration of neurites in cultured adult neurons of Aplysia. Neuroscience. vol 77. issue 3. 1997-06-10. PMID:9070763. |
an analogue of acetylcholine, carbachol, which is not hydrolysed by acetylcholinesterase, did not interfere with neurite growth when added to the supplemented medium. |
1997-06-10 |
2023-08-12 |
human |
| M Srivatsan, B Peret. Acetylcholinesterase promotes regeneration of neurites in cultured adult neurons of Aplysia. Neuroscience. vol 77. issue 3. 1997-06-10. PMID:9070763. |
these results show that i) acetylcholinesterase circulating in the hemolymph promotes neurite growth of adult neurons in culture; ii) the growth promoting action of acetylcholinesterase is independent of its function of hydrolysing acetylcholine and iii) the peripheral anionic site of acetylcholinesterase appears to be involved in neurite regeneration. |
1997-06-10 |
2023-08-12 |
human |
| L H Booi. Neuromuscular transmission and its pharmacological blockade. Part 1: Neuromuscular transmission and general aspects of its blockade. Pharmacy world & science : PWS. vol 19. issue 1. 1997-06-05. PMID:9089749. |
acetylcholine diffuses across the junctional cleft and binds to acetylcholinereceptors at the postjunctional part, and is thereafter metabolized by acetylcholinesterase in the junctional cleft. |
1997-06-05 |
2023-08-12 |
Not clear |
| H Shinoto. [Neurotransmitter systems in the human brain studied by positron emission tomography]. Rinsho shinkeigaku = Clinical neurology. vol 36. issue 12. 1997-05-30. PMID:9128390. |
recently, acetylcholine analogs labelled with positron emitter have been developed for measurement of brain acetylcholinesterase activity in vivo. |
1997-05-30 |
2023-08-12 |
human |