| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H BREUER, M SCHOENFELDE. [Research of the participation of cholinesterase and acetylcholinesterase in the hydrolysis of acetylcholine in serum]. Clinica chimica acta; international journal of clinical chemistry. vol 6. 1998-11-01. PMID:13872954. |
[research of the participation of cholinesterase and acetylcholinesterase in the hydrolysis of acetylcholine in serum]. |
1998-11-01 |
2023-08-12 |
Not clear |
| E DE ROBERTIS, A PELLEGRINO DE IRALDI, G RODRIGUEZ DE LORES GARNAIZ, L SALGANICOF. Cholinergic and non-cholinergic nerve endings in rat brain. I. Isolation and subcellular distribution of acetylcholine and acetylcholinesterase. Journal of neurochemistry. vol 9. 1998-11-01. PMID:13884490. |
isolation and subcellular distribution of acetylcholine and acetylcholinesterase. |
1998-11-01 |
2023-08-12 |
rat |
| K N MEHROTRA, W C DAUTERMA. The specificity of rat brain acetylcholinesterase for N-alkyl analogues of acetylcholine. Journal of neurochemistry. vol 10. 1998-11-01. PMID:13934512. |
the specificity of rat brain acetylcholinesterase for n-alkyl analogues of acetylcholine. |
1998-11-01 |
2023-08-12 |
rat |
| E DE ROBERTIS, L SALGANICOFF, L M ZIEHER, G RODRIGUEZ DE LORES ARNAI. Acetylcholine and cholinacetylase content of synaptic vesicles. Science (New York, N.Y.). vol 140. issue 3564. 1998-11-01. PMID:14026027. |
acetylcholine, cholinacetylase, and acetylcholinesterase were determined in three subfractions that resulted from the osmotic shock of the "mitochondrial" fraction of the rat brain. |
1998-11-01 |
2023-08-12 |
rat |
| E DE ROBERTIS, L SALGANICOFF, L M ZIEHER, G RODRIGUEZ DE LORES ARNAI. Acetylcholine and cholinacetylase content of synaptic vesicles. Science (New York, N.Y.). vol 140. issue 3564. 1998-11-01. PMID:14026027. |
acetylcholine and cholinacetylase were found concentrated in the subfraction that contained mainly synaptic vesicles and some membranes, whereas the larger proportion of the acetylcholinesterase was observed in the subfraction that contained torn nerve endings. |
1998-11-01 |
2023-08-12 |
rat |
| G B KOELL. A new general concept of the neurohumoral functions of acetylcholine and acetylcholinesterase. The Journal of pharmacy and pharmacology. vol 14. 1998-11-01. PMID:14457689. |
a new general concept of the neurohumoral functions of acetylcholine and acetylcholinesterase. |
1998-11-01 |
2023-08-12 |
Not clear |
| S De La Porte, E Chaubourt, F Fabre, K Poulas, J Chapron, B Eymard, S Tzartos, J Koeni. Accumulation of acetylcholine receptors is a necessary condition for normal accumulation of acetylcholinesterase during in vitro neuromuscular synaptogenesis. The European journal of neuroscience. vol 10. issue 5. 1998-10-22. PMID:9751136. |
accumulation of acetylcholine receptors is a necessary condition for normal accumulation of acetylcholinesterase during in vitro neuromuscular synaptogenesis. |
1998-10-22 |
2023-08-12 |
mouse |
| S De La Porte, E Chaubourt, F Fabre, K Poulas, J Chapron, B Eymard, S Tzartos, J Koeni. Accumulation of acetylcholine receptors is a necessary condition for normal accumulation of acetylcholinesterase during in vitro neuromuscular synaptogenesis. The European journal of neuroscience. vol 10. issue 5. 1998-10-22. PMID:9751136. |
to study a step of the very complex processes of the formation of the neuromuscular junction (nmj), we have analysed the clustering of acetylcholine receptors (achr) and acetylcholinesterase (ache) in myotubes cultured in various conditions. |
1998-10-22 |
2023-08-12 |
mouse |
| F H Calderón, R von Bernhardi, G De Ferrari, S Luza, R Aldunate, N C Inestros. Toxic effects of acetylcholinesterase on neuronal and glial-like cells in vitro. Molecular psychiatry. vol 3. issue 3. 1998-10-08. PMID:9672900. |
acetylcholinesterase (ache), the enzyme involved in the hydrolysis of the neurotransmitter acetylcholine, has been implicated in non-cholinergic actions which may play a role in neurodegenerative diseases such as alzheimer's disease. |
1998-10-08 |
2023-08-12 |
Not clear |
| P T Williamson, G Gröbner, P J Spooner, K W Miller, A Watt. Probing the agonist binding pocket in the nicotinic acetylcholine receptor: a high-resolution solid-state NMR approach. Biochemistry. vol 37. issue 30. 1998-08-21. PMID:9692976. |
through the use of computer simulations of chemical shifts carried out on acetylcholine bound to the acetylcholinesterase, we propose that the cause for this change is the presence of aromatic side chains lining the receptor binding site. |
1998-08-21 |
2023-08-12 |
Not clear |
| S R Pereira, G A Menezes, G C Franco, A E Costa, A M Ribeir. Chronic ethanol consumption impairs spatial remote memory in rats but does not affect cortical cholinergic parameters. Pharmacology, biochemistry, and behavior. vol 60. issue 2. 1998-08-17. PMID:9632211. |
moreover, there were no significant differences between treated and control subjects in the following biochemical brain cortical parameters: in vitro acetylcholinesterase (ache) activity, and stimulated acetylcholine (ach) release. |
1998-08-17 |
2023-08-12 |
human |
| G Benzi, A Morett. Is there a rationale for the use of acetylcholinesterase inhibitors in the therapy of Alzheimer's disease? European journal of pharmacology. vol 346. issue 1. 1998-08-04. PMID:9617746. |
this review, therefore, focuses on the complex nature of the acetylcholine system, the alterations of acetylcholinesterase and muscarinic receptor signal transduction in alzheimer's disease, and the involvement of other neurotransmitters. |
1998-08-04 |
2023-08-12 |
Not clear |
| T Sakurai, T Kato, K Mori, E Takano, S Watabe, T Nabeshim. Nefiracetam elevates extracellular acetylcholine level in the frontal cortex of rats with cerebral cholinergic dysfunctions: an in vivo microdialysis study. Neuroscience letters. vol 246. issue 2. 1998-07-28. PMID:9627182. |
we determined the effect of nefiracetam, a novel cognitive enhancer, on the extracellular acetylcholine (ach) level in the frontal cortex of freely moving rats, using a microdialysis technique without an acetylcholinesterase inhibitor in the perfusate. |
1998-07-28 |
2023-08-12 |
rat |
| B Garrone, M R Luparini, L Tolu, M Magnani, C Landolfi, C Milanes. Effect of the subchronic treatment with the acetylcholinesterase inhibitor heptastigmine on central cholinergic transmission and memory impairment in aged rats. Neuroscience letters. vol 245. issue 1. 1998-07-14. PMID:9596354. |
the effect of subchronic administration of the acetylcholinesterase (ache) inhibitor heptastigmine (hep 0.6 mg/kg s.c. daily for 15 days) was investigated on cortical extracellular acetylcholine (ach) levels and on memory function in aged male rats (26 months old at the beginning of the experiments) using microdialysis and behavioural techniques. |
1998-07-14 |
2023-08-12 |
rat |
| R C Choi, L Y Yung, T T Dong, D C Wan, Y H Wong, K W Tsi. The calcitonin gene-related peptide-induced acetylcholinesterase synthesis in cultured chick myotubes is mediated by cyclic AMP. Journal of neurochemistry. vol 71. issue 1. 1998-07-09. PMID:9648861. |
in vertebrate neuromuscular junctions, post-synaptic specialization includes aggregation of acetylcholine receptors (achrs) and acetylcholinesterase (ache). |
1998-07-09 |
2023-08-12 |
chicken |
| W Yao, D A Godfre. Immunohistochemical evaluation of cholinergic neurons in the rat superior olivary complex. Microscopy research and technique. vol 41. issue 3. 1998-07-02. PMID:9605344. |
the cholinergic system in the rat superior olivary complex (soc) was evaluated by immunohistochemistry for choline acetyltransferase (chat) and vesicular acetylcholine transporter (vacht) and histochemistry for acetylcholinesterase (ache). |
1998-07-02 |
2023-08-12 |
rat |
| D Kaufer, A Friedman, S Seidman, H Sore. Acute stress facilitates long-lasting changes in cholinergic gene expression. Nature. vol 393. issue 6683. 1998-06-15. PMID:9620801. |
inhibitors of acetylcholinesterase also promote enhanced electrical brain activity, presumably by increasing the survival of acetylcholine at the synapse. |
1998-06-15 |
2023-08-12 |
Not clear |
| D Kaufer, A Friedman, S Seidman, H Sore. Acute stress facilitates long-lasting changes in cholinergic gene expression. Nature. vol 393. issue 6683. 1998-06-15. PMID:9620801. |
here we report that there is similar bidirectional modulation of genes that regulate acetylcholine availability after stress and blockade of acetylcholinesterase. |
1998-06-15 |
2023-08-12 |
Not clear |
| L E Eide. The cholinergic gene locus. Journal of neurochemistry. vol 70. issue 6. 1998-06-05. PMID:9603187. |
manipulation of vacht expression in vivo has demonstrated unequivocally the primacy of vesicular exocytosis as the mode of transmitting quanta of acetylcholine at the neuromuscular junction, as in vivo manipulation of acetylcholinesterase levels has demonstrated the importance of acetylcholine metabolism in the regulation of complex functions such as cognition. |
1998-06-05 |
2023-08-12 |
human |
| M A Prendergast, A V Terry, J J Buccafusc. Effects of chronic, low-level organophosphate exposure on delayed recall, discrimination, and spatial learning in monkeys and rats. Neurotoxicology and teratology. vol 20. issue 2. 1998-05-14. PMID:9536457. |
chronic exposure to low levels of organophosphate (op) compounds impairs acetylcholine (ach) degradation by acetylcholinesterase (ache) and, in humans, may produce lasting neurotoxicity affecting cognitive function. |
1998-05-14 |
2023-08-12 |
rat |