| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| U P Fringeli, P Hofe. Electric-field induced effects in acetylcholinesterase. Neurochemistry international. vol 2C. 2012-10-02. PMID:20487782. |
since a negative charge on the enzyme facilitates the trapping of positively charged acetylcholine, and this negative charge can be controlled via the potential of the support to which it is adsorbed, a new electrostatic regulation model for acetylcholinesterase activity in excitable membranes is proposed. |
2012-10-02 |
2023-08-12 |
Not clear |
| M Israel, B Lesbat. Chemiluminescent determination of acetylcholine, and continuous detection of its release from torpedo electric organ synapses and synaptosomes. Neurochemistry international. vol 3. issue 1. 2012-10-02. PMID:20487811. |
the specificity of the chemiluminescent method depends on the fact that choline oxidase receives its substrate only when acetylcholine is hydrolysed by acetylcholinesterase. |
2012-10-02 |
2023-08-12 |
Not clear |
| H Bree. Characterization of synaptosomes from the central nervous system of insects. Neurochemistry international. vol 3. issue 2. 2012-10-02. PMID:20487820. |
cholinergic activities (choline acetyltransferase, acetylcholinesterase, acetylcholine receptors) were found to be concentrated in the synaptosomal fraction. |
2012-10-02 |
2023-08-12 |
Not clear |
| P Kása, G Szepesy, K Gulya, K Bánsághy, Z Rakoncza. The effect of 4-(1-naphthylvinyl)-pyridine on the acetylcholine system and on the number of synaptic vesicles in the central nervous system of the rat. Neurochemistry international. vol 4. issue 2-3. 2012-10-02. PMID:20487868. |
the in vivo effects of 4-(1-naphthylvinyl)-pyridine on the activities of choline acetyltransferase and acetylcholinesterase, the levels of acetylcholine and choline, the sodium-dependent high affinity choline uptake and the number of synaptic vesicles were investigated in the rat brain. |
2012-10-02 |
2023-08-12 |
rat |
| D Rodríguez-Ithurralde, R Silveira, L Barbeito, F Daja. Fasciculin, a powerful anticholinesterase polypeptide from Dendroaspis angusticeps venom. Neurochemistry international. vol 5. issue 3. 2012-10-02. PMID:20487949. |
fasciculins represent a new type of acetylcholinesterase inhibitors provoking muscle fasciculations through a powerful inhibition of enzyme activity at the neuromuscular end-plate, interfering with the normal degradative activity of the acetylcholine molecule. |
2012-10-02 |
2023-08-12 |
mouse |
| M Muramatsu, I Arai, J Tamaki, H Hirose, A Fujita, H Aihar. Central regulation of gastric acetylcholine metabolism and acid output Analysis using stress and 2-deoxy-d-glucose administration in rats. Neurochemistry international. vol 8. issue 4. 2012-10-02. PMID:20493088. |
the stress of immobilization in water caused a significant increase in the activity of choline acetyltransferase (cat) and acetylcholinesterase (ache), acetylcholine (ach) content in the stomach and gastric acid secretion, but a decrease of choline content in rats. |
2012-10-02 |
2023-08-12 |
rat |
| H Stadler, T Nesselhu. Simple and rapid measurement of acetylcholine and choline by HPLC and enzymatic-electrochemical detection. Neurochemistry international. vol 9. issue 1. 2012-10-02. PMID:20493110. |
acetylcholine and choline are first separated by hplc then react in a mini-column with acetylcholinesterase and choline oxidase immobilized on sepharose. |
2012-10-02 |
2023-08-12 |
Not clear |
| A Szabó, J Nemcsók, P Kása, K Guly. Muscarinic cholinergic components in the carp brain. Neurochemistry international. vol 15. issue 4. 2012-10-02. PMID:20504527. |
the activity of the muscarinic cholinergic system (acetylcholine, ach; acetylcholinesterase, ache; choline acetyltransferase, chat; muscarinic acetylcholine receptors) was studied in the carp brain. |
2012-10-02 |
2023-08-12 |
Not clear |
| A D Taranalli, T C Cheeramkuzh. Influence of clitoria ternatea extracts on memory and central cholinergic activity in rats. Pharmaceutical biology. vol 38. issue 1. 2012-10-02. PMID:21214440. |
in order to delineate the possible mechanism through which c. ternatea elicits the anti-amnesic effects, we studied its influence on central cholinergic activity by estimating the acetylcholine content of the whole brain and acetylcholinesterase activity at different regions of the rat brain, viz., cerebral cortex, midbrain, medulla oblongata and cerebellum. |
2012-10-02 |
2023-08-12 |
rat |
| S B Mushigeri, M Davi. Fenvalerate induced changes in the Ach and associated AchE activity in different tissues of fish Cirrhinus mrigala (Hamilton) under lethal and sub-lethal exposure period. Environmental toxicology and pharmacology. vol 20. issue 1. 2012-10-02. PMID:21783569. |
the disruption of acetylcholinesterase activity in freshwater fish cirrhinus mrigala (hamilton) is demonstrated in the present study using acetylcholine chloride as substrate. |
2012-10-02 |
2023-08-12 |
Not clear |
| Faiyaz Ahmed, J N Narendra Sharath Chandra, S Manjunat. Acetylcholine and memory-enhancing activity of Ficus racemosa bark. Pharmacognosy research. vol 3. issue 4. 2012-10-02. PMID:22224047. |
alzheimer's disease (ad) is a progressive neurodegenerative disorder resulting in dementia and enhancement of acetylcholine (ach) levels in brain using acetylcholinesterase inhibitors is one of the most important approaches for the treatment of ad. |
2012-10-02 |
2023-08-12 |
Not clear |
| Joanne Knowle. Donepezil in Alzheimer's disease: an evidence-based review of its impact on clinical and economic outcomes. Core evidence. vol 1. issue 3. 2012-10-02. PMID:22500154. |
it is a specific and reversible inhibitor of acetylcholinesterase (ache); by increasing levels of available acetylcholine, donepezil may compensate for the loss of functioning cholinergic brain cells. |
2012-10-02 |
2023-08-12 |
Not clear |
| Miroslav Pohanka, Oto Pavlis, Hana Svobodova, Jiri Pikul. Acetylcholine and an acetylcholinesterase inhibitor neostigmine can aggravate tularemia progress in BALB/c mice. Interdisciplinary toxicology. vol 5. issue 1. 2012-10-02. PMID:22783145. |
acetylcholine and an acetylcholinesterase inhibitor neostigmine can aggravate tularemia progress in balb/c mice. |
2012-10-02 |
2023-08-12 |
mouse |
| Miroslav Pohanka, Oto Pavlis, Hana Svobodova, Jiri Pikul. Acetylcholine and an acetylcholinesterase inhibitor neostigmine can aggravate tularemia progress in BALB/c mice. Interdisciplinary toxicology. vol 5. issue 1. 2012-10-02. PMID:22783145. |
the present experiment was aimed at assessing the application of neostigmine, an acetylcholinesterase (ache) pseudo-irreversible inhibitor with poor penetration through the hematoencephalitic barrier, and the neurotransmitter acetylcholine (ach). |
2012-10-02 |
2023-08-12 |
mouse |
| Ye Li, Xiang-Lin Xie, Ming Zho. [Changes of acetylcholine and acetylcholinesterase in brain tissue of hypoxic tolerance mice]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 24. issue 3. 2012-10-01. PMID:21141583. |
[changes of acetylcholine and acetylcholinesterase in brain tissue of hypoxic tolerance mice]. |
2012-10-01 |
2023-08-12 |
mouse |
| Kamilla Monteiro dos Santos, Priscila Sant'Ana Gonçalves, Maria José Nunes de Paiva, Guilherme Araújo Lacerd. Acetylcholinesterase inhibition starting from extracts of Bauhinia variegata L., Bauhinia var. candida (Aiton) Buch.-Ham., and Bauhinia ungulata L. Revista da Sociedade Brasileira de Medicina Tropical. vol 44. issue 6. 2012-09-27. PMID:22231255. |
candida (aiton) buch.-ham., and bauhinia ungulata l. a treatment to the alzheimer's disease consists inhibition of the acetylcholinesterase, which is responsible for the acetylcholine control in the synapses. |
2012-09-27 |
2023-08-12 |
Not clear |
| Santoshkumar Tota, Chandishwar Nath, Abul Kalam Najmi, Rakesh Shukla, Kashif Hani. Inhibition of central angiotensin converting enzyme ameliorates scopolamine induced memory impairment in mice: role of cholinergic neurotransmission, cerebral blood flow and brain energy metabolism. Behavioural brain research. vol 232. issue 1. 2012-09-27. PMID:22460064. |
scopolamine caused impairment in memory which was associated with reduced cbf, acetylcholine (ach) level and elevated acetylcholinesterase (ache) activity and malondialdehyde (mda) level. |
2012-09-27 |
2023-08-12 |
mouse |
| D Chand Basha, M Usha Rani, C Bhuvaneswari Devi, M Ram Kumar, G Rajarami Redd. Perinatal lead exposure alters postnatal cholinergic and aminergic system in rat brain: reversal effect of calcium co-administration. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 30. issue 4. 2012-09-13. PMID:22326442. |
in this study, we examined the alterations in synaptosomal acetylcholine (ach), epinephrine, dopamine, acetylcholinesterase (ache), and mitochondrial monoamine oxidase (mao) in the cerebellum and hippocampus of perinatally pb-exposed rats. |
2012-09-13 |
2023-08-12 |
rat |
| Jinxu Liu, Huiyin Tu, Dongze Zhang, Yu-Long L. Changes of calcium channel mRNA, protein and current in NG108-15 cells after cell differentiation. Biochemical and biophysical research communications. vol 423. issue 1. 2012-09-13. PMID:22627136. |
based on the characteristics of differentiated ng108-15 cells (cell membrane excitability, acetylcholine release, and activities of choline acetyltransferase and acetylcholinesterase), ng108-15 cells are extensively used to explore neuronal functions as a cholinergic cell line. |
2012-09-13 |
2023-08-12 |
Not clear |
| Sonika Bhardwaj, Nidhi Musalgaonkar, Chandrakant Waghmare, Bijoy K Bhattachary. Single dose exposure of sarin and physostigmine differentially regulates expression of choline acetyltransferase and vesicular acetylcholine transporter in rat brain. Chemico-biological interactions. vol 198. issue 1-3. 2012-09-05. PMID:22640809. |
choline acetyltransferase (chat) and vesicular acetylcholine transporter (vacht) are the key components of cholinergic system apart from acetylcholinesterase. |
2012-09-05 |
2023-08-12 |
rat |