| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O V Tiapkina, L F Nurullin, K A Petrov, E M Volko. [Influence of modeling of gravitational unloading on the postsynaptic acetylcholine receptor organization and acetylcholinesterase activity in neuromuscular synapses of rat fast and slow muscles]. Tsitologiia. vol 56. issue 10. 2015-03-17. PMID:25711085. |
using immunofluorescent techniques, we have revealed that, after 35 days of rats hindlimb unloading, neuromuscular synapses of fast and slow muscles show enhanced fluorescence intensity and decreased area of fluorescent staining of acetylcholine receptors; increased fluorescent intensity and area of fluorescent staining for acetylcholinesterase. |
2015-03-17 |
2023-08-13 |
rat |
| O V Tiapkina, L F Nurullin, K A Petrov, E M Volko. [Influence of modeling of gravitational unloading on the postsynaptic acetylcholine receptor organization and acetylcholinesterase activity in neuromuscular synapses of rat fast and slow muscles]. Tsitologiia. vol 56. issue 10. 2015-03-17. PMID:25711085. |
the ratio of the number of postsynaptic acetylcholine receptors and the amount of acetylcholinesterase changed as well as their spatial position in relation to each other. |
2015-03-17 |
2023-08-13 |
rat |
| O V Tiapkina, L F Nurullin, K A Petrov, E M Volko. [Influence of modeling of gravitational unloading on the postsynaptic acetylcholine receptor organization and acetylcholinesterase activity in neuromuscular synapses of rat fast and slow muscles]. Tsitologiia. vol 56. issue 10. 2015-03-17. PMID:25711085. |
hindlimb unloading (simulation of hypogravity) leads to an increase in functional activity of acetylcholinesterase on the background of reduced postsynaptic membrane area occupied by acetylcholine receptors. |
2015-03-17 |
2023-08-13 |
rat |
| Junying Wang, Junling Liu, Shuping Chen, Yonghui Gao, Fanying Meng, Lina Qia. Acupuncture effects on the hippocampal cholinergic system in a rat model of neuropathic pain. Neural regeneration research. vol 7. issue 3. 2015-03-13. PMID:25767502. |
the present study observed the effects of repeated electroacupuncture of zusanli (st36) and yanglingquan (gb34) on expression of hippocampal acetylcholinesterase, vesicular acetylcholine transporter, and muscarinic m1 receptor mrna in chronic constrictive injury (neuropathic pain) and/or ovariotomy rats. |
2015-03-13 |
2023-08-13 |
rat |
| Junying Wang, Junling Liu, Shuping Chen, Yonghui Gao, Fanying Meng, Lina Qia. Acupuncture effects on the hippocampal cholinergic system in a rat model of neuropathic pain. Neural regeneration research. vol 7. issue 3. 2015-03-13. PMID:25767502. |
results demonstrated increased expression of hippocampal acetylcholinesterase, vesicular acetylcholine transporter, and muscarinic m1 receptor mrna, as well as decreased pain threshold, in a rat model of chronic neuropathic pain after electroacupuncture. |
2015-03-13 |
2023-08-13 |
rat |
| Junying Wang, Junling Liu, Shuping Chen, Yonghui Gao, Fanying Meng, Lina Qia. Acupuncture effects on the hippocampal cholinergic system in a rat model of neuropathic pain. Neural regeneration research. vol 7. issue 3. 2015-03-13. PMID:25767502. |
results indicated that repeated electroacupuncture has a cumulative analgesic effect, which is closely associated with upregulation of acetylcholinesterase and vesicular acetylcholine transporter activity, as well as m1 receptor mrna expression and memory. |
2015-03-13 |
2023-08-13 |
rat |
| Gauresh Somani, Chinmay Kulkarni, Prashant Shinde, Rupesh Shelke, Kirti Laddha, Sadhana Sathay. In vitro acetylcholinesterase inhibition by psoralen using molecular docking and enzymatic studies. Journal of pharmacy & bioallied sciences. vol 7. issue 1. 2015-02-24. PMID:25709334. |
inhibitors of acetylcholinesterase (ache) leading to inhibition of acetylcholine breakdown constitute the main therapeutic strategy for ad. |
2015-02-24 |
2023-08-13 |
Not clear |
| Alejandro Dau, Pragya Komal, Mimi Truong, Geoff Morris, Gareth Evans, Raad Nashm. RIC-3 differentially modulates α4β2 and α7 nicotinic receptor assembly, expression, and nicotine-induced receptor upregulation. BMC neuroscience. vol 14. 2015-02-23. PMID:23586521. |
recent work has shown that the chaperone resistant to inhibitors of acetylcholinesterase (ric-3) is critical for the folding, maturation and functional expression of a variety of neuronal nicotinic acetylcholine receptors. |
2015-02-23 |
2023-08-12 |
xenopus_laevis |
| Nidhi Chauhan, C S Pundi. Amperometric determination of acetylcholine-A neurotransmitter, by chitosan/gold-coated ferric oxide nanoparticles modified gold electrode. Biosensors & bioelectronics. vol 61. 2015-02-20. PMID:24836212. |
an amperometric acetylcholine biosensor was constructed by co-immobilizing covalently, a mixture of acetylcholinesterase (ache) and choline oxidase (cho) onto nanocomposite of chitosan (chit)/gold-coated ferric oxide nanoparticles (fe@aunps) electrodeposited onto surface of a au electrode and using it as a working electrode, ag/agcl as reference electrode and pt wire as auxiliary electrode connected through potentiostat. |
2015-02-20 |
2023-08-13 |
Not clear |
| Ericka C Holmstrand, David Lund, Ajeesh Koshy Cherian, Jane Wright, Rolicia F Martin, Elizabeth A Ennis, Gregg D Stanwood, Martin Sarter, Randy D Blakel. Transgenic overexpression of the presynaptic choline transporter elevates acetylcholine levels and augments motor endurance. Neurochemistry international. vol 73. 2015-02-02. PMID:24274995. |
the hemicholinium-3 (hc-3) sensitive, high-affinity choline transporter (cht) sustains cholinergic signaling via the presynaptic uptake of choline derived from dietary sources or from acetylcholinesterase (ache)-mediated hydrolysis of acetylcholine (ach). |
2015-02-02 |
2023-08-12 |
mouse |
| Siyoung Lee, Jisung Kim, Sang Gwon Seo, Bo-Ryoung Choi, Jung-Soo Han, Ki Won Lee, Jiyoung Ki. Sulforaphane alleviates scopolamine-induced memory impairment in mice. Pharmacological research. vol 85. 2015-01-27. PMID:24836869. |
mice that received scopolamine alone showed impaired learning and memory retention and considerably decreased cholinergic system reactivity in the hippocampus and frontal cortex, as indicated by a decreased acetylcholine (ach) level and an increased acetylcholinesterase (ache) activity. |
2015-01-27 |
2023-08-13 |
mouse |
| Andrew M King, Cynthia K Aaro. Organophosphate and carbamate poisoning. Emergency medicine clinics of North America. vol 33. issue 1. 2015-01-26. PMID:25455666. |
both classes inhibit acetylcholinesterase (ache) enzymes, leading to excess acetylcholine accumulation at nerve terminals. |
2015-01-26 |
2023-08-13 |
Not clear |
| Satoshi Suo, Shoichi Ishiur. Dopamine modulates acetylcholine release via octopamine and CREB signaling in Caenorhabditis elegans. PloS one. vol 8. issue 8. 2015-01-22. PMID:23977320. |
in this study, the effect of dopamine, octopamine, and creb on acetylcholine signaling was analyzed using the acetylcholinesterase inhibitor aldicarb. |
2015-01-22 |
2023-08-12 |
caenorhabditis_elegans |
| C Remya, K V Dileep, I Tintu, E J Variyar, C Sadasiva. Flavanone glycosides as acetylcholinesterase inhibitors: computational and experimental evidence. Indian journal of pharmaceutical sciences. vol 76. issue 6. 2015-01-16. PMID:25593395. |
acetylcholinesterase hydrolyzes the neurotransmitter called acetylcholine and is crucially involved in the regulation of neurotransmission. |
2015-01-16 |
2023-08-13 |
Not clear |
| C Remya, K V Dileep, I Tintu, E J Variyar, C Sadasiva. Flavanone glycosides as acetylcholinesterase inhibitors: computational and experimental evidence. Indian journal of pharmaceutical sciences. vol 76. issue 6. 2015-01-16. PMID:25593395. |
they maintain the level of acetylcholine in the brain by inhibiting the acetylcholinesterase function. |
2015-01-16 |
2023-08-13 |
Not clear |
| Rodrigo Rodrigues, Gabriela Debom, Fabiano Soares, Caroline Machado, Jéssica Pureza, William Peres, Gilberto de Lima Garcias, Marta Frescura Duarte, Maria Rosa Chitolina Schetinger, Francieli Stefanello, Elizandra Braganhol, Roselia Spanevell. Alterations of ectonucleotidases and acetylcholinesterase activities in lymphocytes of Down syndrome subjects: relation with inflammatory parameters. Clinica chimica acta; international journal of clinical chemistry. vol 433. 2015-01-15. PMID:24631131. |
atp, adenosine, and acetylcholine contribute to the immune response regulation, and ntpdase, adenosine deaminase (ada) and acetylcholinesterase (ache) are important enzymes in the control of the extracellular levels of these molecules. |
2015-01-15 |
2023-08-12 |
human |
| M Merad, W Soufi, S Ghalem, F Boukli, M H Baig, K Ahmad, Mohammad A Kama. Molecular interaction of acetylcholinesterase with carnosic acid derivatives: a neuroinformatics study. CNS & neurological disorders drug targets. vol 13. issue 3. 2015-01-07. PMID:24059305. |
acetylcholinesterase (ache) plays a biological role in the termination of nerve impulse transmissions at cholinergic synapses by rapid hydrolysis of its substrate, "acetylcholine". |
2015-01-07 |
2023-08-12 |
Not clear |
| Helen M Campanha, Félix Carvalho, Paul M Schlosse. Active and peripheral anionic sites of acetylcholinesterase have differential modulation effects on cell proliferation, adhesion and neuritogenesis in the NG108-15 cell line. Toxicology letters. vol 230. issue 2. 2014-11-25. PMID:24680925. |
the classical enzymatic role of acetylcholinesterase (ache) is to terminate impulse transmission at cholinergic synapses through rapid hydrolysis of acetylcholine (ach). |
2014-11-25 |
2023-08-12 |
mouse |
| Ali Afrasiabi, Gholam Hossein Riazi, Shayan Abbasi, Ali Dadras, Behafarid Ghalandari, Hossein Seidkhani, Seyed Mohamad Sadegh Modaresi, Neda Masoudian, Amir Amani, Shahin Ahmadia. Synaptosomal acetylcholinesterase activity variation pattern in the presence of electromagnetic fields. International journal of biological macromolecules. vol 65. 2014-11-24. PMID:24418344. |
acetylcholinesterase (ache) is the enzyme that controls the acetylcholine (ach) concentrations in cholinergic synaptic clefts by hydrolyzing ach to choline and acetate. |
2014-11-24 |
2023-08-12 |
Not clear |
| Aliya Ahmad, Kalavathy Ramasamy, Siti Murnirah Jaafar, Abu Bakar Abdul Majeed, Vasudevan Man. Total isoflavones from soybean and tempeh reversed scopolamine-induced amnesia, improved cholinergic activities and reduced neuroinflammation in brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 65. 2014-10-28. PMID:24373829. |
brain cholinergic activities (acetylcholine and acetylcholinesterase) and neuroinflammatory activities (cox-1, cox-2, il-1β and il10) were also assessed. |
2014-10-28 |
2023-08-12 |
rat |