| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carlota Saldanh. Physiological role of erythrocyte nitric oxide. Clinical hemorheology and microcirculation. vol 64. issue 4. 2017-02-24. PMID:27767981. |
a signal transduction mechanism involving protein gi and protein band 3 stimulates erythrocyte no efflux when acetylcholine (ach) binds to erythrocyte membrane acetylcholinesterase. |
2017-02-24 |
2023-08-13 |
Not clear |
| Kitlangki Suchiang, Ramesh Sharm. Age-dependent modulation of fasting and long-term dietary restriction on acetylcholinesterase in non-neuronal tissues of mice. Molecular and cellular biochemistry. vol 419. issue 1-2. 2017-02-01. PMID:27379505. |
acetylcholinesterase (ache), a thoroughly studied enzyme better known for hydrolyzing acetylcholine (ach) in neuronal tissues, has recently been linked with multiple unrelated biological functions in different non-neuronal tissues. |
2017-02-01 |
2023-08-13 |
mouse |
| F J Campoy, C J Vidal, E Muñoz-Delgado, M F Montenegro, J Cabezas-Herrera, S Nieto-Ceró. Cholinergic system and cell proliferation. Chemico-biological interactions. vol 259. issue Pt B. 2017-01-30. PMID:27083142. |
acetylcholinesterase participates in the regulation of cell proliferation and apoptosis through hydrolysis of acetylcholine and by other catalytic and non catalytic mechanisms, in a variant-specific manner. |
2017-01-30 |
2023-08-13 |
human |
| Heidi Q Xie, Tuan Xu, Yangsheng Chen, Yunping Li, Yingjie Xia, Sherry L Xu, Lingyun Wang, Karl W K Tsim, Bin Zha. New perspectives for multi-level regulations of neuronal acetylcholinesterase by dioxins. Chemico-biological interactions. vol 259. issue Pt B. 2017-01-30. PMID:27374124. |
acetylcholinesterase (ache; ec 3.1.1.7) is a vital functional enzyme in cholinergic neurotransmission which can rapidly hydrolyze neurotransmitter, acetylcholine, in the central and peripheral nervous systems. |
2017-01-30 |
2023-08-13 |
mouse |
| Dae Cheol Nam, Yu Mi Ha, Min Kyu Park, Sung Kweon Ch. The rs662 polymorphism of paraoxonase 1 affects the difference in the inhibition of butyrylcholinesterase activity by organophosphorus pesticides in human blood. International journal of clinical pharmacology and therapeutics. vol 54. issue 8. 2017-01-27. PMID:27087156. |
ops inhibit acetylcholinesterase (ache) at nerve endings and accumulate acetylcholine (ach) at these sites. |
2017-01-27 |
2023-08-13 |
human |
| Cho Rong Kim, Soo Jung Choi, Yoon Kyung Kwon, Jae Kyeom Kim, Youn-Jung Kim, Gwi Gun Park, Dong-Hoon Shi. Cinnamomum loureirii Extract Inhibits Acetylcholinesterase Activity and Ameliorates Trimethyltin-Induced Cognitive Dysfunction in Mice. Biological & pharmaceutical bulletin. vol 39. issue 7. 2017-01-27. PMID:27374288. |
the pathogenesis of alzheimer's disease (ad) has been linked to the deficiency of neurotransmitter acetylcholine (ach) in the brain, and the main treatment strategy for improving ad symptoms is the inhibition of acetylcholinesterase (ache) activity. |
2017-01-27 |
2023-08-13 |
mouse |
| Hee Ra Park, Heeeun Lee, Hwayong Park, Won-Kyung Cho, Jin Yeul M. Fermented Sipjeondaebo-tang Alleviates Memory Deficits and Loss of Hippocampal Neurogenesis in Scopolamine-induced Amnesia in Mice. Scientific reports. vol 6. 2017-01-12. PMID:26939918. |
in the hippocampus of sco, oxidative stress and the activity of acetylcholinesterase were elevated, whereas the levels of acetylcholine and choline acetyltransferase were diminished; however, all of these alterations were attenuated by fsj-treatment. |
2017-01-12 |
2023-08-13 |
mouse |
| Katsuyoshi Mizukami, Hiroyasu Akatsu, Eric E Abrahamson, Zhiping Mi, Milos D Ikonomovi. Immunohistochemical analysis of hippocampal butyrylcholinesterase: Implications for regional vulnerability in Alzheimer's disease. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 36. issue 2. 2017-01-09. PMID:26293308. |
studies of acetylcholine degrading enzymes acetylcholinesterase (ache) and butyrylcholinesterase (bche) in alzheimer's disease (ad) have suggested their potential role in the development of fibrillar amyloid-β (aβ) plaques (amyloid plaques). |
2017-01-09 |
2023-08-13 |
Not clear |
| Peng Li, Ya-Ling Yin, Mo-Li Zhu, Guo-Pin Pan, Fan-Rong Zhao, Jun-Xiu Lu, Zhan Liu, Shuang-Xi Wang, Chang-Ping H. Chronic administration of isocarbophos induces vascular cognitive impairment in rats. Journal of cellular and molecular medicine. vol 20. issue 4. 2017-01-06. PMID:26818681. |
long-term administration of isocarbophos reduced the hippocampal acetylcholinesterase (ache) activity and acetylcholine (ach) content but did not alter the plasma ache activity, and significantly damaged the functions of learning and memory. |
2017-01-06 |
2023-08-13 |
rat |
| Alberto Castagna, Antonino Maria Cotroneo, Giovanni Ruotolo, Pietro Garer. The CITIRIVAD Study: CITIcoline plus RIVAstigmine in Elderly Patients Affected with Dementia Study. Clinical drug investigation. vol 36. issue 12. 2017-01-02. PMID:27587069. |
acetylcholinesterase inhibitors (acheis), such as rivastigmine, coadministered with cholinergic precursors, such as citicoline, could be effective in alzheimer's disease (ad) and in mixed dementia (md), because they are able to increase the intrasynaptic levels of acetylcholine more than the single drugs given alone. |
2017-01-02 |
2023-08-13 |
Not clear |
| Meegle S Mathew, Ananya Baksi, T Pradeep, Kuruvilla Josep. Choline-induced selective fluorescence quenching of acetylcholinesterase conjugated Au@BSA clusters. Biosensors & bioelectronics. vol 81. 2016-12-28. PMID:26921554. |
the gold quantum clusters (auqc@bsa) synthesized using bovine serum albumin and conjugated with acetylcholinesterase (ache), an enzyme specific for acetylcholine, resulting in auqc@bsa-ache. |
2016-12-28 |
2023-08-13 |
cattle |
| Pedro Teixeira, Patrícia Napoleão, Carlota Saldanh. S-nitrosoglutathione efflux in the erythrocyte. Clinical hemorheology and microcirculation. vol 60. issue 4. 2016-12-19. PMID:24958331. |
gsno has been regarded as a store and transporter of no, with significant interest as a potential therapeutic agent, acting as an no donor.no metabolism inside the erythrocyte generates several derivatives, which can be altered by external and internal stimuli such as acetylcholine (ach), a natural substrate of acetylcholinesterase (ache). |
2016-12-19 |
2023-08-13 |
Not clear |
| Samanta Oliveira Loureiro, Daniele Susana Volkart Sidegum, Helena Biasibetti, Mery Stefani Leivas Pereira, Diogo Losch de Oliveira, Regina Pessoa-Pureur, Angela T S Wys. Crosstalk Among Disrupted Glutamatergic and Cholinergic Homeostasis and Inflammatory Response in Mechanisms Elicited by Proline in Astrocytes. Molecular neurobiology. vol 53. issue 2. 2016-12-13. PMID:25579384. |
we also evidenced misregulation of cholinergic anti-inflammatory system with increased acetylcholinesterase (ache) activity and decreased acetylcholine (ach) levels, contributing to the inflammatory status in pro-treated astrocytes. |
2016-12-13 |
2023-08-13 |
rat |
| Susimaire P Mantoani, Talita P C Chierrito, Adriana F L Vilela, Carmen L Cardoso, Ana Martínez, Ivone Carvalh. Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors. Molecules (Basel, Switzerland). vol 21. issue 2. 2016-11-07. PMID:26861273. |
currently, the only strategy for palliative treatment of ad is to inhibit acetylcholinesterase (ache) in order to increase the concentration of acetylcholine in the synaptic cleft. |
2016-11-07 |
2023-08-13 |
Not clear |
| Hongna Pan, Tetsade C B Piermartiri, Jun Chen, John McDonough, Craig Oppel, Wafae Driwech, Kristin Winter, Emylee McFarland, Katelyn Black, Taiza Figueiredo, Neil Grunberg, Ann M Marin. Repeated systemic administration of the nutraceutical alpha-linolenic acid exerts neuroprotective efficacy, an antidepressant effect and improves cognitive performance when given after soman exposure. Neurotoxicology. vol 51. 2016-10-12. PMID:26386148. |
exposure to nerve agents results in severe seizures or status epilepticus caused by the inhibition of acetylcholinesterase, a critical enzyme that breaks down acetylcholine to terminate neurotransmission. |
2016-10-12 |
2023-08-13 |
Not clear |
| Fen Liu, Ning Zhao, Donghai Li, Zhenguo Zeng, Qiang Shao, Feifei Peng, Yan Wang, Kejian Qia. [Anti-inflammatory effect of acetylcholine on lipopolysaccharide induced inflammatory response of alveolar macrophages]. Zhonghua wei zhong bing ji jiu yi xue. vol 27. issue 10. 2016-10-05. PMID:27132443. |
to observe the effect of acetylcholine (ach) on lipopolysaccharide (lps) induced inflammatory model of rat alveolar macrophages, and to observe the effect of the acetylcholinesterase inhibitor physostigmine (phy) on the anti-inflammatory effect of ach. |
2016-10-05 |
2023-08-13 |
rat |
| Zehra Batool, Sadia Sadir, Laraib Liaquat, Saiqa Tabassum, Syeda Madiha, Sahar Rafiq, Sumayya Tariq, Tuba Sharf Batool, Sadia Saleem, Fizza Naqvi, Tahira Perveen, Saida Haide. Repeated administration of almonds increases brain acetylcholine levels and enhances memory function in healthy rats while attenuates memory deficits in animal model of amnesia. Brain research bulletin. vol 120. 2016-09-30. PMID:26548495. |
cholinergic function was determined in terms of hippocampal and frontal cortical acetylcholine content and acetylcholinesterase activity. |
2016-09-30 |
2023-08-13 |
rat |
| Zhuo Qu, Jingze Zhang, Honggai Yang, Liqin Huo, Jing Gao, Hong Chen, Wenyuan Ga. Protective effect of tetrahydropalmatine against d-galactose induced memory impairment in rat. Physiology & behavior. vol 154. 2016-09-30. PMID:26592138. |
thp treatment was also found to reverse the abnormality of acetylcholine (ach) levels and acetylcholinesterase (ache) activities. |
2016-09-30 |
2023-08-13 |
rat |
| Gamal Mohamed Mors. Bioaccumulation and neurotoxicity of dithiopyridine herbicide in the brain of freshwater fish, Cyprinus carpio. Toxicology and industrial health. vol 31. issue 12. 2016-09-16. PMID:23681548. |
one-way analysis of variance revealed that the acute and sublethal exposure to the herbicide as well as the experimental periods caused significant reduction in the concentrations of catecholamines (dopamine (da) and norepinephrine (ne)), elevation of acetylcholine (ach), and was associated with a marked decrease in the activity of acetylcholinesterase (ache). |
2016-09-16 |
2023-08-12 |
Not clear |
| Mikhail Stepanichev, Daniil Markov, Natalia Pasikova, Natalia Gulyaev. Behavior and the cholinergic parameters in olfactory bulbectomized female rodents: Difference between rats and mice. Behavioural brain research. vol 297. 2016-09-15. PMID:26431763. |
no effect of obx on the number of cholinergic neurons in the medial septum-diagonal band as well as on the acetylcholine content and acetylcholinesterase activity in the septum, hippocampus, and neocortex could be detected. |
2016-09-15 |
2023-08-13 |
mouse |