| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E KOENIG, G B KOELL. Mode of regeneration of acetylcholinesterase in cholinergic neurons following irreversible inactivation. Journal of neurochemistry. vol 8. 1998-11-01. PMID:14457701. |
mode of regeneration of acetylcholinesterase in cholinergic neurons following irreversible inactivation. |
1998-11-01 |
2023-08-12 |
Not clear |
| L E Tune, T Sunderlan. New cholinergic therapies: treatment tools for the psychiatrist. The Journal of clinical psychiatry. vol 59 Suppl 13. 1998-10-20. PMID:9771828. |
the focus is on pivotal articles investigating the role of cholinergic augmentation strategies, including precursor loading and acetylcholinesterase (ache) inhibitors, in the management of cognitive and noncognitive symptoms of alzheimer's disease. |
1998-10-20 |
2023-08-12 |
Not clear |
| J Winkler, L J Thal, F H Gage, L J Fishe. Cholinergic strategies for Alzheimer's disease. Journal of molecular medicine (Berlin, Germany). vol 76. issue 8. 1998-10-19. PMID:9694432. |
using in vivo rodent models, several cholinergic enhancement strategies have been tested and proven to be effective in alleviating lesion-induced cognitive deficits, including neuropharmacological approaches (acetylcholinesterase inhibitors), neurotrophic factor administration (nerve growth factor), and transplantation of cholinergic-enriched fetal grafts. |
1998-10-19 |
2023-08-12 |
mouse |
| G Amitai, D Moorad, R Adani, B P Docto. Inhibition of acetylcholinesterase and butyrylcholinesterase by chlorpyrifos-oxon. Biochemical pharmacology. vol 56. issue 3. 1998-10-02. PMID:9744565. |
the insecticidal action of chlorpyrifos stems from inhibition of acetylcholinesterase (ache) by cpo, resulting in severe cholinergic toxicity. |
1998-10-02 |
2023-08-12 |
mouse |
| P Taylo. Development of acetylcholinesterase inhibitors in the therapy of Alzheimer's disease. Neurology. vol 51. issue 1 Suppl 1. 1998-07-30. PMID:9674760. |
acetylcholinesterase (ache) inhibitors were first administered in europe to human subjects in the 1860s, and synthetic derivatives of the natural alkaloid inhibitors were developed in the 1930s to modulate peripheral cholinergic function. |
1998-07-30 |
2023-08-12 |
human |
| S Darvesh, D L Grantham, D A Hopkin. Distribution of butyrylcholinesterase in the human amygdala and hippocampal formation. The Journal of comparative neurology. vol 393. issue 3. 1998-07-15. PMID:9548556. |
the distribution of the major cholinergic regulatory enzyme acetylcholinesterase (ache, ec 3.1.1.7) has been extensively studied in the human brain, but the distribution of the closely related enzyme butyrylcholinesterase (buche, ec 3.1.1.8) is largely unknown. |
1998-07-15 |
2023-08-12 |
human |
| B Garrone, M R Luparini, L Tolu, M Magnani, C Landolfi, C Milanes. Effect of the subchronic treatment with the acetylcholinesterase inhibitor heptastigmine on central cholinergic transmission and memory impairment in aged rats. Neuroscience letters. vol 245. issue 1. 1998-07-14. PMID:9596354. |
effect of the subchronic treatment with the acetylcholinesterase inhibitor heptastigmine on central cholinergic transmission and memory impairment in aged rats. |
1998-07-14 |
2023-08-12 |
rat |
| W Yao, D A Godfre. Immunohistochemical evaluation of cholinergic neurons in the rat superior olivary complex. Microscopy research and technique. vol 41. issue 3. 1998-07-02. PMID:9605344. |
the cholinergic system in the rat superior olivary complex (soc) was evaluated by immunohistochemistry for choline acetyltransferase (chat) and vesicular acetylcholine transporter (vacht) and histochemistry for acetylcholinesterase (ache). |
1998-07-02 |
2023-08-12 |
rat |
| B E Mileson, J E Chambers, W L Chen, W Dettbarn, M Ehrich, A T Eldefrawi, D W Gaylor, K Hamernik, E Hodgson, A G Karczmar, S Padilla, C N Pope, R J Richardson, D R Saunders, L P Sheets, L G Sultatos, K B Wallac. Common mechanism of toxicity: a case study of organophosphorus pesticides. Toxicological sciences : an official journal of the Society of Toxicology. vol 41. issue 1. 1998-06-08. PMID:9520337. |
the working group concluded that op pesticides act by a common mechanism of toxicity if they inhibit acetylcholinesterase by phosphorylation and elicit any spectrum of cholinergic effects. |
1998-06-08 |
2023-08-12 |
Not clear |
| J Aisa, M Lahoz, P J Serrano, T Castiella, C Junquera, M J Azanza, A Vera-Gi. Histochemical, immunohistochemical, and electron microscopy study of the caudal portion of the chicken intestinal nerve of Remak. Neurochemical research. vol 23. issue 6. 1998-05-29. PMID:9572673. |
we have found cholinergic cell bodies, as well as acetylcholinesterase (ache) positive neuronal fibers, forming part of the web that constitutes the i.n.r. |
1998-05-29 |
2023-08-12 |
chicken |
| E Apartis, F R Poindessous-Jazat, Y A Lamour, M H Bassan. Loss of rhythmically bursting neurons in rat medial septum following selective lesion of septohippocampal cholinergic system. Journal of neurophysiology. vol 79. issue 4. 1998-05-27. PMID:9535934. |
acetylcholinesterase (ache) histochemistry revealed a near-complete loss of cholinergic septal neurons and of cholinergic fibers in the hippocampus. |
1998-05-27 |
2023-08-12 |
rat |
| T Harkany, S O'Mahony, J P Kelly, K Soós, I Törõ, B Penke, P G Luiten, C Nyakas, K Gulya, B E Leonar. Beta-amyloid(Phe(SO3H)24)25-35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation. Behavioural brain research. vol 90. issue 2. 1998-05-27. PMID:9580273. |
subsequently, acetylcholinesterase (ache) histochemistry was used to visualize alterations of parietal cortical cholinergic innervation. |
1998-05-27 |
2023-08-12 |
rat |
| R T Robertson, K A Gallardo, K J Claytor, D H Ha, K H Ku, B P Yu, J C Lauterborn, R G Wiley, J Yu, C M Gall, F M Lesli. Neonatal treatment with 192 IgG-saporin produces long-term forebrain cholinergic deficits and reduces dendritic branching and spine density of neocortical pyramidal neurons. Cerebral cortex (New York, N.Y. : 1991). vol 8. issue 2. 1998-05-22. PMID:9542893. |
acetylcholinesterase histochemistry demonstrates a marked reduction of the cholinergic axons in neocortex. |
1998-05-22 |
2023-08-12 |
rat |
| A Fisher, R Brandeis, S Chapman, Z Pittel, D M Michaelso. M1 muscarinic agonist treatment reverses cognitive and cholinergic impairments of apolipoprotein E-deficient mice. Journal of neurochemistry. vol 70. issue 5. 1998-05-18. PMID:9572284. |
furthermore, this reversal of cognitive deficit was associated with a parallel increase of histochemically determined brain choline acetyltransferase and acetylcholinesterase levels and with the recovery of these cholinergic markers back to control levels. |
1998-05-18 |
2023-08-12 |
mouse |
| L K Takahashi, C S Go. Glucocorticoid facilitation of cholinergic development in the rat hippocampus. Neuroscience. vol 83. issue 4. 1998-04-14. PMID:9502253. |
one method involved measuring the optical density of acetylcholinesterase, a marker of cholinergic fibres in the hippocampus. |
1998-04-14 |
2023-08-12 |
rat |
| L K Takahashi, C S Go. Glucocorticoid facilitation of cholinergic development in the rat hippocampus. Neuroscience. vol 83. issue 4. 1998-04-14. PMID:9502253. |
in addition, unlike the developing hippocampus, the basolateral nucleus of the amygdala, which is also highly innervated by cholinergic fibres, showed no significant changes in acetylcholinesterase density after adrenalectomy. |
1998-04-14 |
2023-08-12 |
rat |
| P V Hoogland, F Martinez-Garcia, F A Geneser, E Vermeulen-VanderZe. Convergence of thalamic and cholinergic projections in the 'dentate area' of lizards. Brain, behavior and evolution. vol 51. issue 2. 1998-04-09. PMID:9491277. |
from acetylcholinesterase staining in the cxms of representatives of these three lizard families, it appeared that the main cholinergic afferents terminate in the same subregions and the same laminae as the dla projections. |
1998-04-09 |
2023-08-12 |
Not clear |
| C Dávila, C Viteri, P de Castr. [Tacrine]. Revista de medicina de la Universidad de Navarra. vol 41. issue 1. 1998-04-02. PMID:9527715. |
although it was soon demonstrated that cholinergic deficit was not the only change, cholinergic hypothesis has allowed to set several possible therapeutic strategies for these severe disease, the most promising is administration of acetylcholinesterase inhibitors. |
1998-04-02 |
2023-08-12 |
Not clear |
| J M Cermak, T Holler, D A Jackson, J K Blusztaj. Prenatal availability of choline modifies development of the hippocampal cholinergic system. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 12. issue 3. 1998-03-31. PMID:9506479. |
to characterize the neurochemical mechanisms that may mediate this effect, we investigated the development of indices of the cholinergic system in the hippocampus: choline acetyltransferase (chat), acetylcholinesterase (ache), synthesis of acetylcholine (ach) from choline transported by high-affinity choline uptake (hacu), and potassium-evoked ach release. |
1998-03-31 |
2023-08-12 |
rat |
| M Brank, K Zajc-Kreft, S Kreft, R Komel, Z Grubi. Biogenesis of acetylcholinesterase is impaired, although its mRNA level remains normal, in the glucocorticoid-treated rat skeletal muscle. European journal of biochemistry. vol 251. issue 1-2. 1998-03-23. PMID:9492307. |
acetylcholinesterase (ache) is responsible for the hydrolysis of acetylcholine in the neuromuscular junction and other cholinergic synapses. |
1998-03-23 |
2023-08-12 |
rat |