| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Heider, R Schliebs, S Rossner, V Big. Basal forebrain cholinergic immunolesion by 192IgG-saporin: evidence for a presynaptic location of subpopulations of alpha 2- and beta-adrenergic as well as 5-HT2A receptors on cortical cholinergic terminals. Neurochemical research. vol 22. issue 8. 1997-10-22. PMID:9239751. |
to correlate the responses to cholinergic immunolesion in cholinoceptive cortical target regions with cholinergic hypoactivity, quantitative receptor autoradiography to measure adrenoceptors and 5-hydroxytryptamine (5-ht) receptor subtypes, and histochemistry to estimate acetylcholinesterase activity, were performed in adjacent brain sections. |
1997-10-22 |
2023-08-12 |
rat |
| M Heider, R Schliebs, S Rossner, V Big. Basal forebrain cholinergic immunolesion by 192IgG-saporin: evidence for a presynaptic location of subpopulations of alpha 2- and beta-adrenergic as well as 5-HT2A receptors on cortical cholinergic terminals. Neurochemical research. vol 22. issue 8. 1997-10-22. PMID:9239751. |
however, cholinergic immunolesion resulted in significantly reduced alpha 2- and beta-adrenoceptor as well as 5-ht2a receptor binding in a number of cortical and hippocampal regions displaying a reduced activity of acetylcholinesterase, already detectable seven days after a single injection of 192igg-saporin and persisting up to three months post lesion without any significant recovery. |
1997-10-22 |
2023-08-12 |
rat |
| M Gattu, K L Boss, A V Terry, J J Buccafusc. Reversal of scopolamine-induced deficits in navigational memory performance by the seed oil of Celastrus paniculatus. Pharmacology, biochemistry, and behavior. vol 57. issue 4. 1997-10-16. PMID:9259008. |
chronic treatment with cp did not alter brain acetylcholinesterase levels and no signs of cholinergic overstimulation were ever noted during or after treatment. |
1997-10-16 |
2023-08-12 |
rat |
| M Weinstoc. Possible role of the cholinergic system and disease models. Journal of neural transmission. Supplementum. vol 49. 1997-10-03. PMID:9266418. |
memory impairments can be reversed by acetylcholinesterase inhibitors and cholinergic agonists but beneficial effects of these agents in ad patients are small and inconsistent. |
1997-10-03 |
2023-08-12 |
rat |
| X Cousin, C Bo. [Acetylcholinesterase from snake venoms]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 191. issue 3. 1997-10-02. PMID:9295965. |
acetylcholinesterase (ache) plays a key role in cholinergic transmission. |
1997-10-02 |
2023-08-12 |
Not clear |
| G Sberna, J Sáez-Valero, K Beyreuther, C L Masters, D H Smal. The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells. Journal of neurochemistry. vol 69. issue 3. 1997-09-25. PMID:9282941. |
one of the characteristic changes that occurs in alzheimer's disease is the loss of acetylcholinesterase (ache) from both cholinergic and noncholinergic neurons of the brain. |
1997-09-25 |
2023-08-12 |
Not clear |
| M Iyo, H Namba, K Fukushi, H Shinotoh, S Nagatsuka, T Suhara, Y Sudo, K Suzuki, T Iri. Measurement of acetylcholinesterase by positron emission tomography in the brains of healthy controls and patients with Alzheimer's disease. Lancet (London, England). vol 349. issue 9068. 1997-09-15. PMID:9269216. |
acetylcholinesterase activity, a marker for degeneration of the central cholinergic system, has consistently been reported, in necropsy brain studies, to be reduced in the cerebral cortex of patients with alzheimer's disease. |
1997-09-15 |
2023-08-12 |
Not clear |
| W Yao, D A Godfre. Densitometric evaluation of markers for cholinergic transmission in rat superior olivary complex. Neuroscience letters. vol 229. issue 1. 1997-09-12. PMID:9224792. |
cholinergic transmission in the rat superior olivary complex (soc) was assessed by densitometric measurements of labeling with several markers: acetylcholinesterase (ache) histochemistry, choline acetyltransferase (chat) immunohistochemistry, and muscarinic acetylcholine receptor (m35) immunohistochemistry and n-methylscopolamine (nms) binding autoradiography, as well as its subtype 2 (m2) immunohistochemistry. |
1997-09-12 |
2023-08-12 |
rat |
| B J Burgess, J C Adams, J B Nado. Morphologic evidence for innervation of Deiters' and Hensen's cells in the guinea pig. Hearing research. vol 108. issue 1-2. 1997-09-09. PMID:9213124. |
few of the nerve fibers and terminals were positive for acetylcholinesterase, which suggests that they were not collaterals of cholinergic olivocochlear fibers. |
1997-09-09 |
2023-08-12 |
Not clear |
| B V Sastr. Human placental cholinergic system. Biochemical pharmacology. vol 53. issue 11. 1997-09-08. PMID:9264309. |
the components of the cholinergic system-ach, choline acetyltransferase, acetylcholinesterase, butyrylcholinesterase, muscarinic receptors, and nicotinic receptors--in human placenta have been demonstrated by unequivocal methods. |
1997-09-08 |
2023-08-12 |
human |
| T Naumann, T Deller, R Bender, M Frotsche. 192 IgG-saporin-induced loss of cholinergic neurons in the septum abolishes cholinergic sprouting after unilateral entorhinal lesion in the rat. The European journal of neuroscience. vol 9. issue 6. 1997-09-03. PMID:9215714. |
this cholinergic sprouting has been demonstrated by acetylcholinesterase (ache) histochemistry, a method said selectively to label cholinergic septohippocampal fibres in the hippocampus. |
1997-09-03 |
2023-08-12 |
rat |
| C Andres, R Beeri, A Friedman, E Lev-Lehman, S Henis, R Timberg, M Shani, H Sore. Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 15. 1997-08-27. PMID:9223334. |
to explore the possibility that overproduction of neuronal acetylcholinesterase (ache) confers changes in both cholinergic and morphogenic intercellular interactions, we studied developmental responses to neuronal ache overexpression in motoneurons and neuromuscular junctions of ache-transgenic mice. |
1997-08-27 |
2023-08-12 |
mouse |
| P G Layer, J Berger, N Kink. Cholinesterases precede "ON-OFF" channel dichotomy in the embryonic chick retina before onset of synaptogenesis. Cell and tissue research. vol 288. issue 3. 1997-08-15. PMID:9134854. |
both levels can be detected easily in the mature retina by choline acetyltransferase (chat) or by acetylcholinesterase (ache); however, the usefulness of these enzymes as developmental markers is restricted, since chat is detected too late, while ache labels not only cholinergic neuropil. |
1997-08-15 |
2023-08-12 |
chicken |
| S Yamada, T Fujii, K Kawashim. Oral administration of KW-5092, a novel gastroprokinetic agent with acetylcholinesterase inhibitory and acetylcholine release enhancing activities, causes a dose-dependent increase in the blood acetylcholine content of beagle dogs. Neuroscience letters. vol 225. issue 1. 1997-07-24. PMID:9143009. |
oral administration of kw-5092 (10-30 mg/kg), a gastroprokinetic agent with acetylcholinesterase (ache) inhibitory and ach release enhancing activities, caused a dose-dependent increase in the ach content of both the blood and plasma, as well as several behavioral side effects due to peripheral cholinergic stimulation. |
1997-07-24 |
2023-08-12 |
Not clear |
| E J Le. Pharmacology and toxicology of chemical warfare agents. Annals of the Academy of Medicine, Singapore. vol 26. issue 1. 1997-07-22. PMID:9140586. |
once exposure has occurred, the management strategy is to reduce cholinergic activity through the use of atropine as well as to attempt to regenerate acetylcholinesterase with pralidoxime. |
1997-07-22 |
2023-08-12 |
Not clear |
| F Mennicken, R Quirio. Interleukin-2 increases choline acetyltransferase activity in septal-cell cultures. Synapse (New York, N.Y.). vol 26. issue 2. 1997-07-18. PMID:9131776. |
the effect of il-2 on the expression of the cholinergic phenotype was determined using choline acetyltransferase (chat) activity and acetylcholinesterase (ache) cytochemistry. |
1997-07-18 |
2023-08-12 |
Not clear |
| D Franco, A F Moorman, W H Lamer. Expression of the cholinergic signal-transduction pathway components during embryonic rat heart development. The Anatomical record. vol 248. issue 1. 1997-07-18. PMID:9143674. |
to establish whether other components of a cholinergic signal-transduction pathway are present in the embryonic heart, we localised the mrnas encoding choline acetyltransferase (chat), acetylcholinesterase (ache), and the muscarinic receptor isoforms (machrs; m1-m5). |
1997-07-18 |
2023-08-12 |
rat |
| J R Delfs, D M Saroff, Y Nishida, J Friend, C Geul. Effects of NMDA and its antagonists on ventral horn cholinergic neurons in organotypic roller tube spinal cord cultures. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 1. 1997-06-16. PMID:9085191. |
neurotoxic effects of excitatory amino acid (eaa) receptor agonist n-methyl-d-aspartic acid (nmda) and its antagonists on ventral horn cholinergic neurons were studied in organotypic rollertube cultures of spinal cord (otc-scs) using biochemical assays of choline acetyltransferase (chat) and acetylcholinesterase (ache) activity, and ache histochemistry. |
1997-06-16 |
2023-08-12 |
Not clear |
| B S McEwen, S E Alves, K Bulloch, N G Weilan. Ovarian steroids and the brain: implications for cognition and aging. Neurology. vol 48. issue 5 Suppl 7. 1997-06-09. PMID:9153161. |
regulation of the serotonergic system appears to be linked to the presence of estrogen- and progestin-sensitive neurons in the midbrain raphe, whereas the ovarian steroid influence on cholinergic function involves induction of choline acetyltransferase and acetylcholinesterase according to a sexually dimorphic pattern. |
1997-06-09 |
2023-08-12 |
rat |
| T G Beach, W G Honer, L H Hughe. Cholinergic fibre loss associated with diffuse plaques in the non-demented elderly: the preclinical stage of Alzheimer's disease? Acta neuropathologica. vol 93. issue 2. 1997-06-03. PMID:9039461. |
cholinergic fibre densities were estimated in sections stained using acetylcholinesterase (ache) enzyme histochemistry. |
1997-06-03 |
2023-08-12 |
Not clear |