| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Kobayashi, T Suzuki, Y Kasashima, A Motegi, I Sato, N Matsusaka, N Ono, A Miura, F Saito, S Sait. Effects of tri-, di- and monobutyltin on synaptic parameters of the cholinergic system in the cerebral cortex of mice. Japanese journal of pharmacology. vol 72. issue 4. 1997-05-28. PMID:9015740. |
the extent of the inhibitory effects on the cholinergic parameters, apart from the activity of acetylcholinesterase, was slightly greater in the case of tributyltin than dibutyltin, in particularly at the highest concentration (10(-4) m) tested. |
1997-05-28 |
2023-08-12 |
mouse |
| A Mancini, D Valle, G Conte, C Fiumara, M Perrelli, L Fabrizi, A Bianchi, L De Marini. Pre- and postprandial pyridostigmine and oxiracetam effects on growth hormone secretion in anorexia nervosa. Psychoneuroendocrinology. vol 21. issue 7. 1997-05-19. PMID:9044445. |
in a group of 24 anorectic patients in a stabilized phase of the illness, we tested, before and after a standard meal, the gh response to ghrh alone and after pre-treatment with pyridostigmine, an inhibitor of acetylcholinesterase, and, on a different day, with oxiracetam, which stimulates the central cholinergic neurones. |
1997-05-19 |
2023-08-12 |
human |
| A E Reyes, D R Perez, A Alvarez, J Garrido, M K Gentry, B P Doctor, N C Inestros. A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme. Biochemical and biophysical research communications. vol 232. issue 3. 1997-05-19. PMID:9126330. |
a monoclonal antibody (mab) 25b1 directed against fetal bovine-serum acetylcholinesterase (fbs ache) was used to examine the ability of the cholinergic enzyme to promote the assembly of amyloid-beta peptides (a beta) into alzheimerś fibrils. |
1997-05-19 |
2023-08-12 |
Not clear |
| F Autelitano, C Weill, M Goeldner, B Ilie. Covalent labeling of muscarinic acetylcholine receptors by tritiated aryldiazonium photoprobes. Biochemical pharmacology. vol 53. issue 4. 1997-05-01. PMID:9105401. |
these two photoactivatable ligands have proven to be powerful tools for the structural analysis of other cholinergic targets (acetylcholinesterase and the nicotinic acetylcholine receptor) by allowing the characterization of a number of different residues belonging to their acetylcholine-binding domain. |
1997-05-01 |
2023-08-12 |
Not clear |
| N Toda, K Ayajiki, T Okamur. Inhibition of nitroxidergic nerve function by neurogenic acetylcholine in monkey cerebral arteries. The Journal of physiology. vol 498 ( Pt 2). 1997-04-29. PMID:9032692. |
histochemical studies of whole-mount preparations revealed nerve fibres with no synthase and vip immunoreactivity, and also acetylcholinesterase, suggesting the presence of perivascular nitroxidergic, vipergic and cholinergic innervation. |
1997-04-29 |
2023-08-12 |
monkey |
| R Schliebs, A Liebmann, S K Bhattacharya, A Kumar, S Ghosal, V Big. Systemic administration of defined extracts from Withania somnifera (Indian Ginseng) and Shilajit differentially affects cholinergic but not glutamatergic and GABAergic markers in rat brain. Neurochemistry international. vol 30. issue 2. 1997-04-17. PMID:9017665. |
therefore, histochemistry to analyse acetylcholinesterase activity as well as receptor autoradiography to detect cholinergic, glutamatergic and gabaergic receptor subtypes were performed in brain slices from adult male wistar rats, injected intraperitoneally daily with an equimolar mixture of sitoindosides vii-x and withaferin-a (prepared from withania somnifera) or with shilajit, at doses of 40 mg/kg of body weight for 7 days. |
1997-04-17 |
2023-08-12 |
rat |
| F Reisecke. [Therapy approaches in cerebral cognitive deficits--neuropsychiatric aspects]. Wiener medizinische Wochenschrift (1946). vol 146. issue 21-22. 1997-04-04. PMID:9092214. |
one pharmacological approach to enhance cholinergic functions involves inhibiting ach-degradation by inhibiting acetylcholinesterase. |
1997-04-04 |
2023-08-12 |
Not clear |
| R S Jope, L Song, R E Power. Cholinergic activation of phosphoinositide signaling is impaired in Alzheimer's disease brain. Neurobiology of aging. vol 18. issue 1. 1997-04-03. PMID:8983039. |
similar deficits were observed in ad in the responses to five additional cholinergic agonists, including acetylcholine with three different acetylcholinesterase inhibitors. |
1997-04-03 |
2023-08-12 |
Not clear |
| A Martinez-Serrano, P A Hantzopoulos, A Björklun. Ex vivo gene transfer of brain-derived neurotrophic factor to the intact rat forebrain: neurotrophic effects on cholinergic neurons. The European journal of neuroscience. vol 8. issue 4. 1997-04-03. PMID:9081624. |
the cells survived well in the host brain for long periods of time (up to 4 weeks), and induced a hypertrophic response of cholinergic neurons (positive for acetylcholinesterase, choline acetyltransferase or low-affinity nerve growth factor receptor) in the nucleus basalis magnocellularis and striatum. |
1997-04-03 |
2023-08-12 |
human |
| G J Lees, W Leon. Neuronal cytotoxicity of inositol hexakisphosphate (phytate) in the rat hippocampus. Brain research. vol 741. issue 1-2. 1997-04-02. PMID:9001715. |
however, the extrinsic cholinergic innervation of the hippocampus (as estimated by staining for acetylcholinesterase) was unaffected. |
1997-04-02 |
2023-08-12 |
rat |
| C P Smith, G M Bores, W Petko, M Li, D E Selk, D K Rush, F Camacho, J T Winslow, R Fishkin, D M Cunningham, K M Brooks, J Roehr, H B Hartman, L Davis, H M Varga. Pharmacological activity and safety profile of P10358, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease. The Journal of pharmacology and experimental therapeutics. vol 280. issue 2. 1997-03-17. PMID:9023283. |
1-[(3-fluoro-4-pyridinyl)amino]-3-methyl-1(h)-indol-5-yl methyl carbamate (p10358) is a potent, reversible acetylcholinesterase inhibitor that produces central cholinergic stimulation after oral and parental administration in rats and mice. |
1997-03-17 |
2023-08-12 |
mouse |
| J Massoulié, C Legay, A Anselmet, E Krejci, F Coussen, S Bo. Biosynthesis and integration of acetylcholinesterase in the cholinergic synapse. Progress in brain research. vol 109. 1997-03-07. PMID:9009693. |
biosynthesis and integration of acetylcholinesterase in the cholinergic synapse. |
1997-03-07 |
2023-08-12 |
Not clear |
| C Andres, R Beeri, T Huberman, M Shani, H Sore. Cholinergic drug resistance and impaired spatial learning in transgenic mice overexpressing human brain acetylcholinesterase. Progress in brain research. vol 109. 1997-03-07. PMID:9009715. |
cholinergic drug resistance and impaired spatial learning in transgenic mice overexpressing human brain acetylcholinesterase. |
1997-03-07 |
2023-08-12 |
mouse |
| A A Al-Jafar. The inhibitory effect of the neuromuscular blocking agent, gallamine triethiodide, on camel retina acetylcholinesterase activity. Toxicology letters. vol 90. issue 1. 1997-02-27. PMID:9020401. |
the present investigation addresses the mode of inhibition of the camel retinal acetylcholinesterase (ache) activity by gallamine triethiodide, which is known to be a specific non-depolarizing neuromuscular blocking agent and polar cholinergic antagonist. |
1997-02-27 |
2023-08-12 |
Not clear |
| L P Rivor. Irinotecan (CPT-11): a brief overview. Clinical and experimental pharmacology & physiology. vol 23. issue 10-11. 1997-02-19. PMID:8911750. |
although the mechanism for the diarrhoea remains to be defined, the cholinergic toxicity appears to be due to an inhibition of acetylcholinesterase. |
1997-02-19 |
2023-08-12 |
human |
| D Rodríguez-Ithurralde, S Olivera, A La Paz, O Vincent, A Rondea. Glycine effects on glutamate-receptor elicited acetylcholinesterase release from slices and synaptosomes of the spinal ventral horn. Journal of the neurological sciences. vol 139 Suppl. 1997-02-12. PMID:8899663. |
to study the mechanisms by which glutamate-elicited acetylcholinesterase release (gear) might play a part in the pathogenesis of excitotoxically triggered motor neurone disease, and to investigate the interaction of gear with spinal glycinergic mechanisms, we measured acetylcholinesterase (ache) and cholinergic markers, after stimulating ventral horn slices and synaptosomes from the mouse spinal cord, with both glutamate- and glycine-receptor agonists. |
1997-02-12 |
2023-08-12 |
mouse |
| K Komai, S Miyazaki, S Onoe, M Shimo-Oku, S Hishid. Vasomotor nerves of vessels in the human optic nerve. Acta ophthalmologica Scandinavica. vol 73. issue 6. 1997-02-11. PMID:9019374. |
cholinergic nerve fibers were observed by light microscopy after acetylcholinesterase staining by the karnovsky-roots method and tago's modified method. |
1997-02-11 |
2023-08-12 |
human |
| J Strupi Suput, T Turk, P Macek, D Supu. Pseudozoanthoxantin-like compound from Parazoanthus axinellae Adriaticus inhibits acetylcholinesterase. Pflugers Archiv : European journal of physiology. vol 431. issue 6 Suppl 2. 1997-01-16. PMID:8739391. |
acetylcholinesterase is an enzyme responsible for the timely termination of acetylcholine action at muscarinic and nicotinic receptors, so it is essential for the normal function of cholinergic synapses. |
1997-01-16 |
2023-08-12 |
Not clear |
| A Nery da Matta, C B Silva, A Hassón-Voloc. Effect of Mg(2+)-ATP on acetylcholinesterase of Electrophorus electricus (L.). Zeitschrift fur Naturforschung. C, Journal of biosciences. vol 51. issue 1-2. 1997-01-15. PMID:8721214. |
in addition, the data suggest that mg(2+)-atp induced an allosteric modulation of the acetylcholinesterase obtained from electrophorous electricus (l.), and indicate an active adenosine triphosphate participation during cholinergic activity. |
1997-01-15 |
2023-08-12 |
Not clear |
| D J Holt, L B Hersh, C B Sape. Cholinergic innervation in the human striatum: a three-compartment model. Neuroscience. vol 74. issue 1. 1997-01-06. PMID:8843078. |
these compartments were compared to regions defined by distinct levels of acetylcholinesterase immunostaining in adjacent sections; the staining patterns produced by the two cholinergic markers were found to be identical except in some portions of the nucleus accumbens, where acetylcholinesterase immunostaining was found to be more intense than choline acetyltransferase immunostaining. |
1997-01-06 |
2023-08-12 |
human |