| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Talesa, R Romani, M Grauso, G Rosi, E Giovannin. Expression of a single dimeric membrane-bound acetylcholinesterase in Parascaris equorum. Parasitology. vol 115 ( Pt 6). 1998-03-11. PMID:9488877. |
the enzyme, probably functional in cholinergic neurotransmission, is an acetylcholinesterase showing a fairly low substrate specificity with thiocholine esters. |
1998-03-11 |
2023-08-12 |
caenorhabditis_elegans |
| S Chapman, D M Michaelso. Specific neurochemical derangements of brain projecting neurons in apolipoprotein E-deficient mice. Journal of neurochemistry. vol 70. issue 2. 1998-02-24. PMID:9453565. |
the densities of nerve terminals of forebrain cholinergic projections were monitored histochemically by measurements of acetylcholinesterase activity, whereas those of the dopaminergic nigrostriatal pathway, the noradrenergic locus coeruleus cortical projection, and the raphe-cortical serotonergic tract were measured autoradiographically using radioligands that bind specifically to the respective presynaptic transporters of these neuronal tracts. |
1998-02-24 |
2023-08-12 |
mouse |
| Y Zhang, P L Carlen, L Zhan. Kinetics of muscarinic reduction of IsAHP in hippocampal neurons: effects of acetylcholinesterase inhibitors. Journal of neurophysiology. vol 78. issue 6. 1998-02-05. PMID:9405519. |
the present experiments were designed to elucidate the time frame in which an evoked cholinergic impulse decreases the ca2+-dependent k+ current (isahp) in hippocampal ca1 neurons, and to determine to what extent acetylcholinesterase (ache) inhibitors enhance the efficacy of the cholinergic impulse. |
1998-02-05 |
2023-08-12 |
rat |
| K Fecho, K A Maslonek, L A Dykstra, D T Lysl. Acetylcholinesterase monoclonal antibody-induced sympathectomy: effects on immune status and acute morphine-induced immunomodulation. Brain, behavior, and immunity. vol 11. issue 3. 1998-02-04. PMID:9417803. |
experimental rats received tail vein injections of murine monoclonal igg2b antibodies against rat brain acetylcholinesterase, which produce a destruction of cholinergic, sympathetic preganglionic neurons and a resultant decrease in sympathetic activity. |
1998-02-04 |
2023-08-12 |
rat |
| R Camarini, M A Benedit. Chronic imipramine treatment-induced changes in acetylcholinesterase (EC 3.1.1.7) activity in discrete rat brain regions. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 30. issue 8. 1998-01-26. PMID:9361724. |
in order to identify possible changes in cholinergic neurotransmission we measured total, membrane-bound and soluble acetylcholinesterase (achase) activity in several rat brain regions after chronic imipramine treatment. |
1998-01-26 |
2023-08-12 |
rat |
| S K Tayebati, M Giannella, S R Indraccolo, M Pigini, M Sabbatini, D Zaccheo, F Ament. Muscarinic cholinergic receptors and acetylcholinesterase activity in umbilical artery and vein in pregnancy-induced hypertension (pre-eclampsia). Clinical and experimental hypertension (New York, N.Y. : 1993). vol 19. issue 8. 1998-01-20. PMID:9385471. |
muscarinic cholinergic receptors and acetylcholinesterase activity in umbilical artery and vein in pregnancy-induced hypertension (pre-eclampsia). |
1998-01-20 |
2023-08-12 |
human |
| S K Tayebati, M Giannella, S R Indraccolo, M Pigini, M Sabbatini, D Zaccheo, F Ament. Muscarinic cholinergic receptors and acetylcholinesterase activity in umbilical artery and vein in pregnancy-induced hypertension (pre-eclampsia). Clinical and experimental hypertension (New York, N.Y. : 1993). vol 19. issue 8. 1998-01-20. PMID:9385471. |
the influence of pregnancy-induced hypertension (pre-eclampsia) on muscarinic cholinergic receptors and on acetylcholinesterase (ache) activity was investigated using frozen sections of the umbilical artery and vein. |
1998-01-20 |
2023-08-12 |
human |
| M L Nonet, O Saifee, H Zhao, J B Rand, L We. Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 1. 1998-01-16. PMID:9412487. |
the viable mutants are resistant to the acetylcholinesterase inhibitor aldicarb, indicating that cholinergic transmission is impaired. |
1998-01-16 |
2023-08-12 |
caenorhabditis_elegans |
| I Abrahám, A H Veenema, C Nyakas, T Harkany, B G Bohus, P G Luite. Effect of corticosterone and adrenalectomy on NMDA-induced cholinergic cell death in rat magnocellular nucleus basalis. Journal of neuroendocrinology. vol 9. issue 9. 1997-12-23. PMID:9355039. |
the neurotoxic impact of the nmda injection in the various experimental groups was assessed by the loss of cholinergic fibers stained with acetylcholinesterase histochemistry in the parietal neocortex. |
1997-12-23 |
2023-08-12 |
rat |
| K Mizukami, A Mishizen, M D Ikonomovic, R Sheffield, D M Armstrong, A Mishizi. Alterations of AMPA-selected glutamate subtype immunoreactivity in the dentate gyrus after perforant pathway lesion. Brain research. vol 768. issue 1-2. 1997-12-18. PMID:9369338. |
completeness of the lesion was confirmed following examination of nissl-stained tissue sections at all times post-lesion and acetylcholinesterase (ache)-stained sections 14, 30 and 90 days post-lesion, the latter providing evidence of compensatory sprouting of cholinergic fibers in the outer molecular layer of the dentate gyrus. |
1997-12-18 |
2023-08-12 |
rat |
| R Beeri, N Le Novère, R Mervis, T Huberman, E Grauer, J P Changeux, H Sore. Enhanced hemicholinium binding and attenuated dendrite branching in cognitively impaired acetylcholinesterase-transgenic mice. Journal of neurochemistry. vol 69. issue 6. 1997-12-12. PMID:9375677. |
in a search for behavioral, neuroanatomical, and metabolic characteristics of alzheimer's disease that may result from cholinergic malfunction, we used transgenic mice overexpressing acetylcholinesterase (ache) mrna and active enzyme in brain neurons. |
1997-12-12 |
2023-08-12 |
mouse |
| K K Hicks, E Seifen, J R Stimers, R H Kenned. Diabetes with and without ketoacidosis on right atrial pacemaker rate and autonomic responsiveness. The American journal of physiology. vol 273. issue 4. 1997-12-10. PMID:9362257. |
the sensitivity to the negative chronotropic action of acetylcholine was enhanced by iddm, whereas the response to carbachol (a cholinergic agonist not readily metabolized by acetylcholinesterase) was not changed. |
1997-12-10 |
2023-08-12 |
rat |
| M L Capece, R Lydi. cAMP and protein kinase A modulate cholinergic rapid eye movement sleep generation. The American journal of physiology. vol 273. issue 4. 1997-12-10. PMID:9362309. |
microinjection of cholinergic agonists and acetylcholinesterase inhibitors into the mprf induces a rem sleep-like state, and microdialysis data reveal increased mprf levels of acetylcholine during rem sleep. |
1997-12-10 |
2023-08-12 |
Not clear |
| J A Bergado, H Moreno, N Nuñe. Fimbria-fornix lesion impairs long-term potentiation in the dentate gyrus of the rat. Biological research. vol 29. issue 2. 1997-12-02. PMID:9278710. |
acetylcholinesterase histochemistry confirmed a severe reduction of the cholinergic innervation to the hippocampal formation, suggesting a causal relationship to the deficits seen in long-term potentiation. |
1997-12-02 |
2023-08-12 |
rat |
| I E Mazzoni, R L Kenigsber. Transforming growth factor-alpha's effects on astroglial-cholinergic cell interactions in the medial septal area in vitro are mediated by alpha 2-macroglobulin. Neuroscience. vol 81. issue 4. 1997-11-26. PMID:9330364. |
we reported previously that two epidermal growth factor receptor ligands, epidermal growth factor and transforming growth factor-alpha, inhibit medial septal cholinergic cell phenotypic expression (choline acetyltransferase and acetylcholinesterase activities) in vitro indirectly via (a) soluble molecule(s) released from astrocytes [kenigsberg r. l. et al. |
1997-11-26 |
2023-08-12 |
Not clear |
| M L Nonet, J E Staunton, M P Kilgard, T Fergestad, E Hartwieg, H R Horvitz, E M Jorgensen, B J Meye. Caenorhabditis elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesicles. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 21. 1997-11-20. PMID:9334382. |
furthermore, rab-3 animals were resistant to the acetylcholinesterase inhibitor aldicarb, suggesting that cholinergic transmission was generally depressed. |
1997-11-20 |
2023-08-12 |
mouse |
| M Koga, H Miyata, N Tsuno, K Nakayama, S Ushijima, Y Tanaka, Y Hiraga, N Kobayash. [Relationship between cholinergic symptoms caused by distigmine and the activities of serum AChE and BChE]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 17. issue 3. 1997-11-19. PMID:9278940. |
we evaluated the possibility of using serum acetylcholinesterase (ache) and butyrylcholinesterase (bche) as specific clinical markers for the adverse cholinergic effects of distigmine. |
1997-11-19 |
2023-08-12 |
Not clear |
| D P Hill, K A Robertso. Characterization of the cholinergic neuronal differentiation of the human neuroblastoma cell line LA-N-5 after treatment with retinoic acid. Brain research. Developmental brain research. vol 102. issue 1. 1997-11-19. PMID:9298234. |
following induction with ra, the neural crest-like la-n-5 cells undergo differentiation into cholinergic neurons with increased expression of a variety of neural-specific markers including neurofilaments, growth associated protein-43, tetanus toxin binding sites, receptors for neurotrophic factors, neuropeptides, choline acetyl transferase, vesicular acetylcholine transporter, and acetylcholinesterase with a concomitant decrease in the expression of non-neuronal markers. |
1997-11-19 |
2023-08-12 |
human |
| E Förster, T Naumann, T Deller, A Straube, R Nitsch, M Frotsche. Cholinergic sprouting in the rat fascia dentata after entorhinal lesion is not linked to early changes in neurotrophin messenger RNA expression. Neuroscience. vol 80. issue 3. 1997-10-27. PMID:9276489. |
however, in spite of this blockade, the typical cholinergic sprouting response as visualized with acetylcholinesterase histochemistry was present in animals four weeks after entorhinal cortex lesion. |
1997-10-27 |
2023-08-12 |
rat |
| C Erb, J Klein, A Köppen, K Löffelholz, H Jeltsch, J C Casse. Modulation of hippocampal acetylcholine release after fimbria-fornix lesions and septal transplantation in rats. Neuroscience letters. vol 231. issue 1. 1997-10-23. PMID:9280154. |
the extent of cholinergic (re)innervation was determined by acetylcholinesterase (ache) staining and densitometry. |
1997-10-23 |
2023-08-12 |
rat |