| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Venero, M Revuelta, A Machado, J Can. Delayed apoptotic pyramidal cell death in CA4 and CA1 hippocampal subfields after a single intraseptal injection of kainate. Neuroscience. vol 94. issue 4. 2000-02-14. PMID:10625049. |
acetylcholinesterase histochemistry revealed a profound loss of staining in the medial septum but not in the diagonal band, and cholinergic fiber density was highly reduced in the hippocampus and amygdala at 10 days postinjection. |
2000-02-14 |
2023-08-12 |
rat |
| Y Li, L Liu, J Kang, J G Sheng, S W Barger, R E Mrak, W S Griffi. Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 1. 2000-01-27. PMID:10627591. |
cholinergic dysfunction in alzheimer's disease has been attributed to stress-induced increases in acetylcholinesterase (ache) activity. |
2000-01-27 |
2023-08-12 |
rat |
| T Arendt, K Lehmann, G Seeger, U Gärtne. Synergistic effects of tetrahydroaminoacridine and lithium on cholinergic function after excitotoxic basal forebrain lesions in rat. Pharmacopsychiatry. vol 32. issue 6. 2000-01-12. PMID:10599934. |
rats received ibotenic acid lesions of cholinergic basal forebrain nuclei resulting in a 30% to 40% depletion of both cortical choline acetyltransferase (chat) and acetylcholinesterase (ache) activity. |
2000-01-12 |
2023-08-12 |
rat |
| X Cousin, C Bo. Acetylcholinesterase from snake venom as a model for its nerve and muscle counterpart. Journal of natural toxins. vol 8. issue 2. 1999-10-18. PMID:10410339. |
acetylcholinesterase (ache) plays a key role in cholinergic transmission. |
1999-10-18 |
2023-08-12 |
Not clear |
| Y Bulut, S R Kleeberger, C A Hirshma. Cholinesterase activity is similar in C3H/HeJ and A/J mice and does not account for their different bronchoconstrictor responsiveness. Experimental lung research. vol 25. issue 5. 1999-10-15. PMID:10483521. |
we conclude that differences in either acetylcholinesterase or butyrylcholinesterase in the a/j or c3h/hej mouse strains are unlikely to contribute to the differences in airway responsiveness to exogenously administered cholinergic agonists. |
1999-10-15 |
2023-08-12 |
mouse |
| S Kuma. Aluminium-induced biphasic effect. Medical hypotheses. vol 52. issue 6. 1999-10-12. PMID:10459838. |
in vitro and in vivo studies have demonstrated an aluminium-induced biphasic effect on the marker enzyme of cholinergic system, acetylcholinesterase. |
1999-10-12 |
2023-08-12 |
Not clear |
| O Rahimi, D E Eslin, G F Hill, S L Julian. Nerve growth factor increases stimulus-evoked metabolic activity in acetylcholine-depleted barrel cortex. Somatosensory & motor research. vol 16. issue 2. 1999-10-04. PMID:10449063. |
the mechanism of ngf action is not clear since the restoration of functional activity in cortex was not accompanied by increased cholinergic activity as detected by acetylcholinesterase fiber staining. |
1999-10-04 |
2023-08-12 |
rat |
| H Shinoto. [PET study of cholinergic system in the brain]. Rinsho shinkeigaku = Clinical neurology. vol 39. issue 1. 1999-09-15. PMID:10377794. |
recently, we have developed a method to measure acetylcholinesterase (ache) activity, a functional marker for cholinergic system, by positron emission tomography (pet) and carbon-11 labeled n-methyl-4-piperidyl acetate. |
1999-09-15 |
2023-08-12 |
human |
| C A Nurse, M Zhan. Acetylcholine contributes to hypoxic chemotransmission in co-cultures of rat type 1 cells and petrosal neurons. Respiration physiology. vol 115. issue 2. 1999-08-27. PMID:10385033. |
recent evidence has strengthened the case for acetylcholine (ach) as a co-released transmitter: (i) cultured type 1 cells express several cholinergic markers including the vesicular ach transporter (vacht), intracellular acetylcholinesterase (ache), and occasional clear cored vesicles (approximately 50 nm diameter); (ii) the frequency of spontaneous synaptic activity, as well as the hypoxia-induced depolarization recorded in 'juxtaposed' pn in co-culture, were partially suppressed by the nicotinic ach receptor (nachr) blocker, mecamylamine (2 microm); (iii) consistent with the presence of extracellular ache, ach-mediated membrane noise in type 1 cells as well as the hypoxia-evoked pn response in co-culture were potentiated in a few cases by the ache inhibitor, eserine (100 microm). |
1999-08-27 |
2023-08-12 |
rat |
| M Srivatsa. Effects of organophosphates on cholinesterase activity and neurite regeneration in Aplysia. Chemico-biological interactions. vol 119-120. 1999-08-19. PMID:10421473. |
in aplysia, a marine mollusc, acetylcholinesterase (ache) is present in cholinergic and non-cholinergic neurons and in hemolymph. |
1999-08-19 |
2023-08-12 |
aplysia |
| U Simonsen, D Triguero, A García-Sacristán, D Priet. Cholinergic modulation of non-adrenergic, non-cholinergic relaxation in isolated, small coronary arteries from lambs. Pflugers Archiv : European journal of physiology. vol 438. issue 2. 1999-08-03. PMID:10370104. |
the presence of cholinergic innervation of small coronary arteries in the lamb was investigated by measuring choline acetyltransferase (chat) and acetylcholinesterase (ache) activities and by performing in vitro experiments in a microvascular myograph to establish whether or not there is a cholinergic component in the response to electrical field stimulation (efs). |
1999-08-03 |
2023-08-12 |
Not clear |
| H Shinotoh, H Namba, M Yamaguchi, K Fukushi, S Nagatsuka, M Iyo, M Asahina, T Hattori, S Tanada, T Iri. Positron emission tomographic measurement of acetylcholinesterase activity reveals differential loss of ascending cholinergic systems in Parkinson's disease and progressive supranuclear palsy. Annals of neurology. vol 46. issue 1. 1999-08-02. PMID:10401781. |
positron emission tomographic measurement of acetylcholinesterase activity reveals differential loss of ascending cholinergic systems in parkinson's disease and progressive supranuclear palsy. |
1999-08-02 |
2023-08-12 |
human |
| G Bicke. Histochemistry of classical neurotransmitters in antennal lobes and mushroom bodies of the honeybee. Microscopy research and technique. vol 45. issue 3. 1999-07-15. PMID:10344769. |
acetylcholinesterase histochemistry, immunocytochemical staining for nicotinic acetylcholine receptors, and mapping for alpha-bungarotoxin binding sites indicate cholinergic synaptic interactions in the antennal lobe and a cholinergic pathway via a subset of olfactory projection neurons into the mushroom bodies. |
1999-07-15 |
2023-08-12 |
bee |
| R E Papka, H H Traurig, M Schemann, J Collins, T Copelin, K Wilso. Cholinergic neurons of the pelvic autonomic ganglia and uterus of the female rat: distribution of axons and presence of muscarinic receptors. Cell and tissue research. vol 296. issue 2. 1999-07-12. PMID:10382273. |
uterine cholinergic nerves arise from the paracervical ganglia and were, in the past, characterized based on acetylcholinesterase (ache) histochemistry. |
1999-07-12 |
2023-08-12 |
rat |
| R E Papka, H H Traurig, M Schemann, J Collins, T Copelin, K Wilso. Cholinergic neurons of the pelvic autonomic ganglia and uterus of the female rat: distribution of axons and presence of muscarinic receptors. Cell and tissue research. vol 296. issue 2. 1999-07-12. PMID:10382273. |
however, the histochemical reaction for acetylcholinesterase provides only indirect evidence of acetylcholine location and is a nonspecific marker for cholinergic nerves. |
1999-07-12 |
2023-08-12 |
rat |
| S Rossner, N Bakinde, U Zeitschel, R Schliebs, V Big. Cerebrospinal fluid cholinesterases--markers for loss of cholinergic basal forebrain neurons? International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 16. issue 7-8. 1999-07-07. PMID:10198815. |
to address this question enzyme activities of acetylcholinesterase (ache) and butyrylcholinesterase (bche) in both csf and parietal cortex were assayed following selective lesion of basal forebrain cholinergic neurons by a single intracerebroventricular application of the cholinergic immunotoxin 192igg-saporin. |
1999-07-07 |
2023-08-12 |
Not clear |
| G Mehlhorn, T Löffler, J Apelt, S Rossner, T Urabe, N Hattori, S Nagamatsu, V Bigl, R Schlieb. Glucose metabolism in cholinoceptive cortical rat brain regions after basal forebrain cholinergic lesion. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 16. issue 7-8. 1999-07-07. PMID:10198816. |
basal forebrain cholinergic lesion resulted in transient increases in glucose transporter binding in cortical regions displaying reduced acetylcholinesterase activity, already detectable seven days after lesion with peak values around 30 days post lesion. |
1999-07-07 |
2023-08-12 |
rat |
| S Olivera, D Rodriguez-Ithurralde, J M Henle. Acetylcholinesterase potentiates [3H]fluorowillardiine and [3H]AMPA binding to rat cortical membranes. Neuropharmacology. vol 38. issue 4. 1999-07-02. PMID:10221754. |
in addition to its action at cholinergic synapses acetylcholinesterase (ache) has been proposed to modulate neuronal activity by mechanisms unrelated to the hydrolysis of acetylcholine. |
1999-07-02 |
2023-08-12 |
rat |
| K Kato, H Hayako, Y Ishihara, S Marui, M Iwane, M Miyamot. TAK-147, an acetylcholinesterase inhibitor, increases choline acetyltransferase activity in cultured rat septal cholinergic neurons. Neuroscience letters. vol 260. issue 1. 1999-06-18. PMID:10027686. |
tak-147, an acetylcholinesterase inhibitor, increases choline acetyltransferase activity in cultured rat septal cholinergic neurons. |
1999-06-18 |
2023-08-12 |
rat |
| K Kato, H Hayako, Y Ishihara, S Marui, M Iwane, M Miyamot. TAK-147, an acetylcholinesterase inhibitor, increases choline acetyltransferase activity in cultured rat septal cholinergic neurons. Neuroscience letters. vol 260. issue 1. 1999-06-18. PMID:10027686. |
tak-147, a potent acetylcholinesterase (ache) inhibitor, potentiated choline acetyltransferase (chat) activity in cultured rat septal cholinergic neurons in a concentration-dependent manner with an ec50 value of 4.47 nm. |
1999-06-18 |
2023-08-12 |
rat |