| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Margaret Rukstalis, Christopher Jepson, Andrew Strasser, Kevin G Lynch, Kenneth Perkins, Freda Patterson, Caryn Lerma. Naltrexone reduces the relative reinforcing value of nicotine in a cigarette smoking choice paradigm. Psychopharmacology. vol 180. issue 1. 2006-02-13. PMID:15682300. |
naltrexone and bupropion have been shown to alter ad lib smoking behavior; however, medication effects on nicotine reward in a cigarette choice paradigm have yet to be investigated. |
2006-02-13 |
2023-08-12 |
human |
| Neil E Paterson, Adrie W Bruijnzeel, Paul J Kenny, Cory D Wright, Wolfgang Froestl, Athina Marko. Prolonged nicotine exposure does not alter GABA(B) receptor-mediated regulation of brain reward function. Neuropharmacology. vol 49. issue 7. 2006-01-30. PMID:16005474. |
prolonged nicotine exposure does not alter gaba(b) receptor-mediated regulation of brain reward function. |
2006-01-30 |
2023-08-12 |
rat |
| Neil E Paterson, Adrie W Bruijnzeel, Paul J Kenny, Cory D Wright, Wolfgang Froestl, Athina Marko. Prolonged nicotine exposure does not alter GABA(B) receptor-mediated regulation of brain reward function. Neuropharmacology. vol 49. issue 7. 2006-01-30. PMID:16005474. |
the present studies investigated whether chronic nicotine administration, using a regimen that induces nicotine dependence, increased inhibitory regulation of brain reward function by gaba(b) receptors, as measured by intracranial self-stimulation (icss) thresholds in rats. |
2006-01-30 |
2023-08-12 |
rat |
| Neil E Paterson, Adrie W Bruijnzeel, Paul J Kenny, Cory D Wright, Wolfgang Froestl, Athina Marko. Prolonged nicotine exposure does not alter GABA(B) receptor-mediated regulation of brain reward function. Neuropharmacology. vol 49. issue 7. 2006-01-30. PMID:16005474. |
such an action of nicotine may contribute to the reward deficit observed during nicotine withdrawal. |
2006-01-30 |
2023-08-12 |
rat |
| Neil E Paterson, Adrie W Bruijnzeel, Paul J Kenny, Cory D Wright, Wolfgang Froestl, Athina Marko. Prolonged nicotine exposure does not alter GABA(B) receptor-mediated regulation of brain reward function. Neuropharmacology. vol 49. issue 7. 2006-01-30. PMID:16005474. |
overall, these data demonstrate that prolonged nicotine exposure did not alter gaba(b) receptor-mediated regulation of brain reward function, and suggest that alterations in gaba(b) receptor activity are unlikely to play a role in the brain reward deficits associated with spontaneous nicotine withdrawal. |
2006-01-30 |
2023-08-12 |
rat |
| Julie A Blendy, Andrew Strasser, Carrie L Walters, Kenneth A Perkins, Freda Patterson, Robert Berkowitz, Caryn Lerma. Reduced nicotine reward in obesity: cross-comparison in human and mouse. Psychopharmacology. vol 180. issue 2. 2005-12-07. PMID:15719224. |
reduced nicotine reward in obesity: cross-comparison in human and mouse. |
2005-12-07 |
2023-08-12 |
mouse |
| Bernard Le Foll, Steven R Goldberg, Pierre Sokolof. The dopamine D3 receptor and drug dependence: effects on reward or beyond? Neuropharmacology. vol 49. issue 4. 2005-12-07. PMID:15963538. |
abused drugs (alcohol, heroin, cocaine, tetrahydrocannabinol and nicotine) elicit a variety of chronically relapsing disorders by interacting with brain reward systems. |
2005-12-07 |
2023-08-12 |
mouse |
| Nasir H Naqvi, Antoine Bechar. The airway sensory impact of nicotine contributes to the conditioned reinforcing effects of individual puffs from cigarettes. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:15996724. |
here, we examined the extent to which reward from puffs can be derived from the airway sensory effect of nicotine, in the absence of a direct central nervous system effect of nicotine. |
2005-11-28 |
2023-08-12 |
Not clear |
| Nasir H Naqvi, Antoine Bechar. The airway sensory impact of nicotine contributes to the conditioned reinforcing effects of individual puffs from cigarettes. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:15996724. |
we did this by assessing the self-reported reward obtained from individual puffs from nicotinized, denicotinized and unlit cigarettes within 7 s of inhalation, which is before nicotine had an opportunity to reach the brain. |
2005-11-28 |
2023-08-12 |
Not clear |
| Nasir H Naqvi, Antoine Bechar. The airway sensory impact of nicotine contributes to the conditioned reinforcing effects of individual puffs from cigarettes. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:15996724. |
we also found that the extent to which nicotine elicited reward was directly correlated with the extent to which nicotine elicited airway sensations. |
2005-11-28 |
2023-08-12 |
Not clear |
| Nasir H Naqvi, Antoine Bechar. The airway sensory impact of nicotine contributes to the conditioned reinforcing effects of individual puffs from cigarettes. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:15996724. |
this indicates that the airway sensory effects of nicotine contribute to the reward from puffs, above and beyond the reward derived from the airway sensory effects of non-nicotine constituents. |
2005-11-28 |
2023-08-12 |
Not clear |
| Nasir H Naqvi, Antoine Bechar. The airway sensory impact of nicotine contributes to the conditioned reinforcing effects of individual puffs from cigarettes. Pharmacology, biochemistry, and behavior. vol 81. issue 4. 2005-11-28. PMID:15996724. |
these findings have implications for the interpretation of studies that use puffs as experimental units to examine nicotine reward. |
2005-11-28 |
2023-08-12 |
Not clear |
| M C Graci. Exposure to nicotine is probably a major cause of inflammatory diseases among non-smokers. Medical hypotheses. vol 65. issue 2. 2005-09-16. PMID:15922096. |
even in very 'light' passive smokers, the repeated nicotinic stimulation of the reward system can produce, through classical and subsequent operant conditioning, unconscious addiction to most relevant perceptions occurring simultaneously, including the artificial, non-localised sensation of pain or sickness caused by the action of nicotine on the nociceptive 'cholinergic anti-inflammatory pathway'. |
2005-09-16 |
2023-08-12 |
Not clear |
| Carrie L Walters, Jessica N Cleck, Yuo-chen Kuo, Julie A Blend. Mu-opioid receptor and CREB activation are required for nicotine reward. Neuron. vol 46. issue 6. 2005-08-16. PMID:15953421. |
mu-opioid receptor and creb activation are required for nicotine reward. |
2005-08-16 |
2023-08-12 |
mouse |
| Carrie L Walters, Jessica N Cleck, Yuo-chen Kuo, Julie A Blend. Mu-opioid receptor and CREB activation are required for nicotine reward. Neuron. vol 46. issue 6. 2005-08-16. PMID:15953421. |
moreover, a single administration of an opioid receptor antagonist, naloxone, blocks both the conditioned molecular response (creb phosphorylation) and the conditioned behavioral response (nicotine reward) in a place preference paradigm. |
2005-08-16 |
2023-08-12 |
mouse |
| Rick A Bevins, Matthew I Palmatie. Extending the role of associative learning processes in nicotine addiction. Behavioral and cognitive neuroscience reviews. vol 3. issue 3. 2005-05-17. PMID:15653812. |
for example, nicotine serves as a conditional stimulus acquiring new appetitive/affective properties when paired with a non-drug reward. |
2005-05-17 |
2023-08-12 |
Not clear |
| S Rossi, S Singer, E Shearman, H Sershen, A Lajth. Regional heterogeneity of nicotine effects on neurotransmitters in rat brains in vivo at low doses. Neurochemical research. vol 30. issue 1. 2005-04-08. PMID:15756937. |
the effects of a low nicotine dose are more significant in areas of reward function, indicating differences in sensitivity between cognitive and reward functions. |
2005-04-08 |
2023-08-12 |
rat |
| Bernard Le Foll, Steven R Goldber. Cannabinoid CB1 receptor antagonists as promising new medications for drug dependence. The Journal of pharmacology and experimental therapeutics. vol 312. issue 3. 2005-04-05. PMID:15525797. |
cannabinoid cb(1) receptors are expressed in this brain reward circuit and modulate the dopamine-releasing effects of delta(9)-thc and nicotine. |
2005-04-05 |
2023-08-12 |
Not clear |
| Rachel F Genn, S Tucci, S Parikh, S E Fil. Effects of nicotine and a cannabinoid receptor agonist on negative contrast: distinction between anxiety and disappointment? Psychopharmacology. vol 177. issue 1-2. 2005-03-23. PMID:15205871. |
both nicotine and a cannabinoid receptor agonist have been reported to change anxiety and both have actions on the reward process, but their effects on snc have not been investigated. |
2005-03-23 |
2023-08-12 |
Not clear |
| Daiichiro Nakahar. Influence of nicotine on brain reward systems: study of intracranial self-stimulation. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542753. |
influence of nicotine on brain reward systems: study of intracranial self-stimulation. |
2005-02-18 |
2023-08-12 |
Not clear |