| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Kota, B R Martin, S E Robinson, M I Dama. Nicotine dependence and reward differ between adolescent and adult male mice. The Journal of pharmacology and experimental therapeutics. vol 322. issue 1. 2007-08-30. PMID:17446302. |
nicotine dependence and reward differ between adolescent and adult male mice. |
2007-08-30 |
2023-08-12 |
mouse |
| Raad Nashmi, Cheng Xiao, Purnima Deshpande, Sheri McKinney, Sharon R Grady, Paul Whiteaker, Qi Huang, Tristan McClure-Begley, Jon M Lindstrom, Cesar Labarca, Allan C Collins, Michael J Marks, Henry A Leste. Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 31. 2007-08-28. PMID:17670967. |
although the midbrain dopaminergic system dominates reward pathways, chronic nicotine does not change alpha4* receptor levels in dopaminergic neurons of ventral tegmental area (vta) or substantia nigra pars compacta. |
2007-08-28 |
2023-08-12 |
mouse |
| George B Stefano, Enrica Bianchi, Massimo Guarna, Gregory L Fricchione, Wei Zhu, Patrick Cadet, Kirk J Mantione, Federico M Casares, Richard M Kream, Tobias Esc. Nicotine, alcohol and cocaine coupling to reward processes via endogenous morphine signaling: the dopamine-morphine hypothesis. Medical science monitor : international medical journal of experimental and clinical research. vol 13. issue 6. 2007-08-17. PMID:17534245. |
nicotine, alcohol and cocaine coupling to reward processes via endogenous morphine signaling: the dopamine-morphine hypothesis. |
2007-08-17 |
2023-08-12 |
Not clear |
| Neil E Paterson, David J Balfour, Athina Marko. Chronic bupropion attenuated the anhedonic component of nicotine withdrawal in rats via inhibition of dopamine reuptake in the nucleus accumbens shell. The European journal of neuroscience. vol 25. issue 10. 2007-08-17. PMID:17561823. |
we also assessed the effects of chronic bupropion on behavioral aspects of nicotine withdrawal measured by elevations in brain reward thresholds and somatic signs of withdrawal. |
2007-08-17 |
2023-08-12 |
human |
| Neil E Paterson, David J Balfour, Athina Marko. Chronic bupropion attenuated the anhedonic component of nicotine withdrawal in rats via inhibition of dopamine reuptake in the nucleus accumbens shell. The European journal of neuroscience. vol 25. issue 10. 2007-08-17. PMID:17561823. |
cessation of nicotine administration in non-bupropion-treated rats elevated reward thresholds reflecting a reward deficit, increased somatic signs and diminished potassium-evoked dopamine overflow in the nucleus accumbens shell. |
2007-08-17 |
2023-08-12 |
human |
| Neil E Paterson, David J Balfour, Athina Marko. Chronic bupropion attenuated the anhedonic component of nicotine withdrawal in rats via inhibition of dopamine reuptake in the nucleus accumbens shell. The European journal of neuroscience. vol 25. issue 10. 2007-08-17. PMID:17561823. |
chronic bupropion lowered reward thresholds and increased potassium-evoked dopamine release regardless of previous nicotine exposure, possibly by inhibition of dopamine reuptake, and thus attenuated the anhedonic and neurochemical effects of nicotine withdrawal. |
2007-08-17 |
2023-08-12 |
human |
| Neil E Paterson, David J Balfour, Athina Marko. Chronic bupropion attenuated the anhedonic component of nicotine withdrawal in rats via inhibition of dopamine reuptake in the nucleus accumbens shell. The European journal of neuroscience. vol 25. issue 10. 2007-08-17. PMID:17561823. |
finally, acute experimenter-administered nicotine enhanced brain reward function equally in all groups, indicating that bupropion does not alter the reward-facilitating effects of experimenter-administered nicotine. |
2007-08-17 |
2023-08-12 |
human |
| b' Megan J Shram, Douglas Funk, Zhaoxia Li, A D L\\xc3\\xa. Acute nicotine enhances c-fos mRNA expression differentially in reward-related substrates of adolescent and adult rat brain. Neuroscience letters. vol 418. issue 3. 2007-08-03. PMID:17420096.' |
the current results suggest that nicotine may have greater activational effects in brain regions associated with reward in adolescent rats and may help to explain the differences between adolescents and adults in behavioral responses to nicotine. |
2007-08-03 |
2023-08-12 |
rat |
| Matthew I Palmatier, Gina L Matteson, Jessica J Black, Xiu Liu, Anthony R Caggiula, Laure Craven, Eric C Donny, Alan F Sve. The reinforcement enhancing effects of nicotine depend on the incentive value of non-drug reinforcers and increase with repeated drug injections. Drug and alcohol dependence. vol 89. issue 1. 2007-08-01. PMID:17240084. |
we have hypothesized that nicotine has two effects on reinforcement; it increases the probability of responses resulting in nicotine delivery (primary reinforcement) and enhances the apparent reward value of non-nicotine reinforcers (reinforcement enhancing effect). |
2007-08-01 |
2023-08-12 |
rat |
| Matthew I Palmatier, Gina L Matteson, Jessica J Black, Xiu Liu, Anthony R Caggiula, Laure Craven, Eric C Donny, Alan F Sve. The reinforcement enhancing effects of nicotine depend on the incentive value of non-drug reinforcers and increase with repeated drug injections. Drug and alcohol dependence. vol 89. issue 1. 2007-08-01. PMID:17240084. |
the present studies investigated two predictions generated by this hypothesis: (1) that the reinforcement enhancing effect will depend on apparent stimulus reward value and (2) that the temporal profile of this effect would depend on the pharmacological profile of nicotine. |
2007-08-01 |
2023-08-12 |
rat |
| Reuven Dar, Hanan Fren. Reevaluating the nicotine delivery kinetics hypothesis. Psychopharmacology. vol 192. issue 1. 2007-06-26. PMID:17404711. |
this potential anomaly to the nicotine addiction thesis is resolved by the proposition that the reward associated with smoking depends on "high-nicotine boli." |
2007-06-26 |
2023-08-12 |
Not clear |
| M K Ho, R F Tyndal. Overview of the pharmacogenomics of cigarette smoking. The pharmacogenomics journal. vol 7. issue 2. 2007-06-20. PMID:17224913. |
much attention has focused on genes involved in the neurotransmitter pathways for the brain reward system and genes altering nicotine metabolism. |
2007-06-20 |
2023-08-12 |
Not clear |
| J Gallinat, F Schuber. Regional cerebral glutamate concentrations and chronic tobacco consumption. Pharmacopsychiatry. vol 40. issue 2. 2007-06-13. PMID:17447175. |
increasing evidence indicates a crucial role of glutamate in the brain reward system and nicotine addiction. |
2007-06-13 |
2023-08-12 |
human |
| Elisabet Jerlhag, Emil Egecioglu, Suzanne L Dickson, Annika Douhan, Lennart Svensson, Jörgen A Enge. Ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens. Addiction biology. vol 12. issue 1. 2007-05-30. PMID:17407492. |
these effects of ghrelin are mediated via central nicotine receptors, suggesting that ghrelin can activate the acetylcholine-dopamine reward link. |
2007-05-30 |
2023-08-12 |
mouse |
| Neil E Paterson, Athina Marko. Animal models and treatments for addiction and depression co-morbidity. Neurotoxicity research. vol 11. issue 1. 2007-05-22. PMID:17449445. |
we explored experimentally whether clinical antidepressant medications or other treatments would reverse the anhedonia observed in rats undergoing spontaneous nicotine or amphetamine withdrawal, defined operationally as elevated brain reward thresholds. |
2007-05-22 |
2023-08-12 |
rat |
| N Hamdani, J Ades, P Gorwoo. [Heritability and candidate genes in tobacco use]. L'Encephale. vol 32. issue 6 Pt 1. 2007-05-18. PMID:17372541. |
because of the brain reward effects of nicotine on the mesolimbic system, the genes involved in the dopaminergic transmission receive specific attention. |
2007-05-18 |
2023-08-12 |
human |
| Piotr Tutka, Witold Zatońsk. Cytisine for the treatment of nicotine addiction: from a molecule to therapeutic efficacy. Pharmacological reports : PR. vol 58. issue 6. 2007-05-11. PMID:17220536. |
recent pharmacological research has elucidated that the drug is a low efficacy partial agonist of alpha4beta2 nicotinic acetylcholine receptors, which are believed to be central to the effect of nicotine (nic) on the reward pathway. |
2007-05-11 |
2023-08-12 |
Not clear |
| Adrie W Bruijnzeel, George Zislis, Carrie Wilson, Mark S Gol. Antagonism of CRF receptors prevents the deficit in brain reward function associated with precipitated nicotine withdrawal in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 4. 2007-05-01. PMID:16943772. |
antagonism of crf receptors prevents the deficit in brain reward function associated with precipitated nicotine withdrawal in rats. |
2007-05-01 |
2023-08-12 |
rat |
| Adrie W Bruijnzeel, George Zislis, Carrie Wilson, Mark S Gol. Antagonism of CRF receptors prevents the deficit in brain reward function associated with precipitated nicotine withdrawal in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 4. 2007-05-01. PMID:16943772. |
the aim of our experiments was to investigate the role of brain crf systems in the deficit in brain reward function associated with the cessation of nicotine administration in rats. |
2007-05-01 |
2023-08-12 |
rat |
| Adrie W Bruijnzeel, George Zislis, Carrie Wilson, Mark S Gol. Antagonism of CRF receptors prevents the deficit in brain reward function associated with precipitated nicotine withdrawal in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 4. 2007-05-01. PMID:16943772. |
in the follow-up experiment, it was shown that pretreatment with the corticotropin-receptor antagonist d-phe crf((12-41)) prevents the elevations in brain reward thresholds associated with precipitated nicotine withdrawal. |
2007-05-01 |
2023-08-12 |
rat |