| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Steven R Laviolette, Nicole M Lauzon, Stephanie F Bishop, Ninglei Sun, Huibing Ta. Dopamine signaling through D1-like versus D2-like receptors in the nucleus accumbens core versus shell differentially modulates nicotine reward sensitivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 32. 2008-09-09. PMID:18685027. |
in contrast, nacore infusions of a d(1)-like receptor antagonist switched intra-vta nicotine aversion to reward, and potentiated reward sensitivity to sub-reward threshold nicotine doses. |
2008-09-09 |
2023-08-12 |
Not clear |
| Astrid K Stoker, Svetlana Semenova, Athina Marko. Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL/6J and BALB/cByJ mice. Neuropharmacology. vol 54. issue 8. 2008-08-25. PMID:18452957. |
the current study is one of the first to demonstrate reward deficits associated with both spontaneous and nachr antagonist-precipitated nicotine withdrawal in c57bl/6j mice. |
2008-08-25 |
2023-08-12 |
mouse |
| Paul M Johnson, Jonathan A Hollander, Paul J Kenn. Decreased brain reward function during nicotine withdrawal in C57BL6 mice: evidence from intracranial self-stimulation (ICSS) studies. Pharmacology, biochemistry, and behavior. vol 90. issue 3. 2008-08-25. PMID:18466962. |
decreased brain reward function during nicotine withdrawal in c57bl6 mice: evidence from intracranial self-stimulation (icss) studies. |
2008-08-25 |
2023-08-12 |
mouse |
| Paul M Johnson, Jonathan A Hollander, Paul J Kenn. Decreased brain reward function during nicotine withdrawal in C57BL6 mice: evidence from intracranial self-stimulation (ICSS) studies. Pharmacology, biochemistry, and behavior. vol 90. issue 3. 2008-08-25. PMID:18466962. |
deficits in brain reward function during nicotine withdrawal may serve as an important substrate for negative reinforcement that contributes to the persistence of the tobacco habit in human smokers. |
2008-08-25 |
2023-08-12 |
mouse |
| Paul M Johnson, Jonathan A Hollander, Paul J Kenn. Decreased brain reward function during nicotine withdrawal in C57BL6 mice: evidence from intracranial self-stimulation (ICSS) studies. Pharmacology, biochemistry, and behavior. vol 90. issue 3. 2008-08-25. PMID:18466962. |
the ability to assess withdrawal-associated reward deficits in genetically modified mice may facilitate understanding of the neurobiological mechanisms of nicotine dependence. |
2008-08-25 |
2023-08-12 |
mouse |
| Paul M Johnson, Jonathan A Hollander, Paul J Kenn. Decreased brain reward function during nicotine withdrawal in C57BL6 mice: evidence from intracranial self-stimulation (ICSS) studies. Pharmacology, biochemistry, and behavior. vol 90. issue 3. 2008-08-25. PMID:18466962. |
here, we assessed the effects of nicotine withdrawal on brain reward function in mice, as measured by intracranial self-stimulation (icss) thresholds. |
2008-08-25 |
2023-08-12 |
mouse |
| Paul M Johnson, Jonathan A Hollander, Paul J Kenn. Decreased brain reward function during nicotine withdrawal in C57BL6 mice: evidence from intracranial self-stimulation (ICSS) studies. Pharmacology, biochemistry, and behavior. vol 90. issue 3. 2008-08-25. PMID:18466962. |
these data demonstrate that antagonist-precipitated or spontaneous withdrawal from nicotine delivered via osmotic minipumps induced reward deficits in mice. |
2008-08-25 |
2023-08-12 |
mouse |
| Ryan M Franke, Minjung Park, James D Belluzzi, Frances M Lesli. Prenatal nicotine exposure changes natural and drug-induced reinforcement in adolescent male rats. The European journal of neuroscience. vol 27. issue 11. 2008-08-20. PMID:18588535. |
these findings suggest that nicotine exposure during gestation may induce changes in both natural and drug reward pathways. |
2008-08-20 |
2023-08-12 |
rat |
| E Shearman, S Fallon, H Sershen, A Lajth. Nicotine-induced monoamine neurotransmitter changes in the brain of young rats. Brain research bulletin. vol 76. issue 6. 2008-08-19. PMID:18598854. |
thus, increases of nicotine reward are not likely due to increases of monoamines in reward and cognitive areas. |
2008-08-19 |
2023-08-12 |
rat |
| Lisa L Merritt, B R Martin, C Walters, A H Lichtman, M Imad Dama. The endogenous cannabinoid system modulates nicotine reward and dependence. The Journal of pharmacology and experimental therapeutics. vol 326. issue 2. 2008-08-12. PMID:18451315. |
the endogenous cannabinoid system modulates nicotine reward and dependence. |
2008-08-12 |
2023-08-12 |
mouse |
| Lisa L Merritt, B R Martin, C Walters, A H Lichtman, M Imad Dama. The endogenous cannabinoid system modulates nicotine reward and dependence. The Journal of pharmacology and experimental therapeutics. vol 326. issue 2. 2008-08-12. PMID:18451315. |
in our study, complementary transgenic and pharmacological approaches were used to test the hypothesis that the endocannabinoid system modulates nicotine reward and dependence. |
2008-08-12 |
2023-08-12 |
mouse |
| Lisa L Merritt, B R Martin, C Walters, A H Lichtman, M Imad Dama. The endogenous cannabinoid system modulates nicotine reward and dependence. The Journal of pharmacology and experimental therapeutics. vol 326. issue 2. 2008-08-12. PMID:18451315. |
however, disruption of cb(1) receptor signaling blocked nicotine reward, as assessed in the conditioned place preference (cpp) paradigm. |
2008-08-12 |
2023-08-12 |
mouse |
| Lisa L Merritt, B R Martin, C Walters, A H Lichtman, M Imad Dama. The endogenous cannabinoid system modulates nicotine reward and dependence. The Journal of pharmacology and experimental therapeutics. vol 326. issue 2. 2008-08-12. PMID:18451315. |
specifically, increasing endogenous cannabinoid levels magnifies, although disrupting cb(1) receptor signaling, attenuates nicotine reward and withdrawal. |
2008-08-12 |
2023-08-12 |
mouse |
| Neil E Paterson, Styliani Vlachou, Sebastien Guery, Klemens Kaupmann, Wolfgang Froestl, Athina Marko. Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats. The Journal of pharmacology and experimental therapeutics. vol 326. issue 1. 2008-07-30. PMID:18445779. |
positive modulation of gaba(b) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats. |
2008-07-30 |
2023-08-12 |
rat |
| Ruth S Barr, Diego A Pizzagalli, Melissa A Culhane, Donald C Goff, A Eden Evin. A single dose of nicotine enhances reward responsiveness in nonsmokers: implications for development of dependence. Biological psychiatry. vol 63. issue 11. 2008-07-16. PMID:17976537. |
a single dose of nicotine enhances reward responsiveness in nonsmokers: implications for development of dependence. |
2008-07-16 |
2023-08-12 |
Not clear |
| Patricia Vieyra-Reyes, Marina R Picciotto, Yann S Mineu. Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors. Neuroscience letters. vol 434. issue 1. 2008-07-03. PMID:18261852. |
these modifications can modulate nicotine reward and reinforcement, but also anxiety and depression-related behaviors. |
2008-07-03 |
2023-08-12 |
mouse |
| Theodore A Slotki. If nicotine is a developmental neurotoxicant in animal studies, dare we recommend nicotine replacement therapy in pregnant women and adolescents? Neurotoxicology and teratology. vol 30. issue 1. 2008-06-23. PMID:18380035. |
importantly, the long-term alterations include effects on reward systems that reinforce the subsequent susceptibility to nicotine addiction in later life. |
2008-06-23 |
2023-08-12 |
Not clear |
| Heather Walsh, Anitha P Govind, Ryan Mastro, J C Hoda, Daniel Bertrand, Yolanda Vallejo, William N Gree. Up-regulation of nicotinic receptors by nicotine varies with receptor subtype. The Journal of biological chemistry. vol 283. issue 10. 2008-05-30. PMID:18174175. |
recent evidence suggests that in addition to alpha4beta2 and alpha3-containing nicotinic receptors, alpha6-containing receptors are present in midbrain dopaminergic neurons and involved in the nicotine reward pathway. |
2008-05-30 |
2023-08-12 |
Not clear |
| Abel Lajth. Interrelated mechanisms in reward and learning. Neurochemistry international. vol 52. issue 1-2. 2008-05-05. PMID:17935832. |
here, we discuss reward processes, which we define as changes examined after administration of nicotine, cocaine or food, each of which induces changes in neurotransmitter levels and functions in cognitive areas as well as in reward areas. |
2008-05-05 |
2023-08-12 |
Not clear |
| Anthony S Rauhut, Isaac J Zentner, Stacey K Mardekian, Jason B Tanenbau. Wistar Kyoto and Wistar rats differ in the affective and locomotor effects of nicotine. Physiology & behavior. vol 93. issue 1-2. 2008-04-22. PMID:17889041. |
anhedonia is a characteristic of clinical depression and has been associated with dysfunction of the mesolimbic dopaminergic system, a system also involved in mediating nicotine reward. |
2008-04-22 |
2023-08-12 |
rat |