| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pretal P Muldoon, Aron H Lichtman, Loren H Parsons, M Imad Dama. The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence. Life sciences. vol 92. issue 8-9. 2013-04-17. PMID:22705310. |
the role of fatty acid amide hydrolase inhibition in nicotine reward and dependence. |
2013-04-17 |
2023-08-12 |
mouse |
| Pretal P Muldoon, Aron H Lichtman, Loren H Parsons, M Imad Dama. The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence. Life sciences. vol 92. issue 8-9. 2013-04-17. PMID:22705310. |
in this mini review, we describe the functional consequences of faah inhibition on nicotine reward and dependence as well as the underlying endocannabinoid and non-cannabinoid receptor systems mediating these effects. |
2013-04-17 |
2023-08-12 |
mouse |
| Pretal P Muldoon, Aron H Lichtman, Loren H Parsons, M Imad Dama. The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence. Life sciences. vol 92. issue 8-9. 2013-04-17. PMID:22705310. |
indeed, pharmacological and genetic faah disruption in mice enhances nicotine reward and withdrawal. |
2013-04-17 |
2023-08-12 |
mouse |
| Pretal P Muldoon, Aron H Lichtman, Loren H Parsons, M Imad Dama. The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence. Life sciences. vol 92. issue 8-9. 2013-04-17. PMID:22705310. |
however, in rats, pharmacological blockade of faah significantly inhibits nicotine reward and has no effect in nicotine withdrawal. |
2013-04-17 |
2023-08-12 |
mouse |
| Dominika Karolczak, Magdalena Wilk, Agata Błaszczyk, Łukasz Szylberg, Monika Seget, Ewa Florek, Andrzej Marszałe. [The awareness of addictive effect of nicotine --a questionnaire survey of students and employees of CM UMK]. Przeglad lekarski. vol 69. issue 10. 2013-04-10. PMID:23421052. |
many studies in humans and in animal models have shown that nicotine is addictive psychoactive drug, which triggers a cascade of neurobiological events in the brain reward centers leading to the intensity of behavior what aims to enhanced use of tobacco. |
2013-04-10 |
2023-08-12 |
human |
| Monica R F Hilario, Jill R Turner, Julie A Blend. Reward sensitization: effects of repeated nicotine exposure and withdrawal in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 12. 2013-03-22. PMID:22828747. |
reward sensitization: effects of repeated nicotine exposure and withdrawal in mice. |
2013-03-22 |
2023-08-12 |
mouse |
| Monica R F Hilario, Jill R Turner, Julie A Blend. Reward sensitization: effects of repeated nicotine exposure and withdrawal in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 12. 2013-03-22. PMID:22828747. |
how these multiple cycles of smoking and withdrawal contribute to nicotine dependence, long-term alterations in brain reward systems, and nicotine receptor regulation is unknown. |
2013-03-22 |
2023-08-12 |
mouse |
| Monica R F Hilario, Jill R Turner, Julie A Blend. Reward sensitization: effects of repeated nicotine exposure and withdrawal in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 12. 2013-03-22. PMID:22828747. |
therefore, to evaluate how multiple exposures of nicotine and withdrawal periods modulate rewarding properties of nicotine, we used intracranial self-stimulation to measure alterations in the threshold of brain stimulation reward. |
2013-03-22 |
2023-08-12 |
mouse |
| Monica R F Hilario, Jill R Turner, Julie A Blend. Reward sensitization: effects of repeated nicotine exposure and withdrawal in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 12. 2013-03-22. PMID:22828747. |
we found that repeated nicotine exposure and withdrawal enhanced brain stimulation reward and reward sensitivity to acute injections of nicotine. |
2013-03-22 |
2023-08-12 |
mouse |
| Monica R F Hilario, Jill R Turner, Julie A Blend. Reward sensitization: effects of repeated nicotine exposure and withdrawal in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 12. 2013-03-22. PMID:22828747. |
this increased reward was reflected by enhanced cpp to nicotine. |
2013-03-22 |
2023-08-12 |
mouse |
| Monica R F Hilario, Jill R Turner, Julie A Blend. Reward sensitization: effects of repeated nicotine exposure and withdrawal in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 12. 2013-03-22. PMID:22828747. |
these results demonstrate that repeated exposures to nicotine, followed by withdrawal, induce a persistent increase in both brain reward function and sensitivity to the hedonic value of nicotine and long-lasting up-regulation of neuronal nicotinic receptors. |
2013-03-22 |
2023-08-12 |
mouse |
| Monica R F Hilario, Jill R Turner, Julie A Blend. Reward sensitization: effects of repeated nicotine exposure and withdrawal in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 12. 2013-03-22. PMID:22828747. |
together, these data suggest that a continuing increase in brain reward function and enhanced sensitivity to nicotine reward following repeated withdrawal periods may be one reason why smokers relapse frequently. |
2013-03-22 |
2023-08-12 |
mouse |
| Xiang Yang Zhang, Da Chun Chen, Mei Hong Xiu, Li Hui, Haibo Liu, Xingguang Luo, Lingjun Zuo, Huiping Zhang, Therese A Kosten, Thomas R Koste. Association of functional dopamine-beta-hydroxylase (DBH) 19 bp insertion/deletion polymorphism with smoking severity in male schizophrenic smokers. Schizophrenia research. vol 141. issue 1. 2013-02-13. PMID:22871345. |
the mechanism for such an association may reflect nicotine's mediation of drug reward in the brain through actions on dopamine, a key mediator of drug reward. |
2013-02-13 |
2023-08-12 |
Not clear |
| Hao Chen, Katie A Hiler, Elizabeth A Tolley, Shannon G Matta, Burt M Shar. Genetic factors control nicotine self-administration in isogenic adolescent rat strains. PloS one. vol 7. issue 8. 2013-02-12. PMID:22937166. |
the correlation between nicotine and food reward was not significant. |
2013-02-12 |
2023-08-12 |
human |
| Hao Chen, Katie A Hiler, Elizabeth A Tolley, Shannon G Matta, Burt M Shar. Genetic factors control nicotine self-administration in isogenic adolescent rat strains. PloS one. vol 7. issue 8. 2013-02-12. PMID:22937166. |
hence, the genetic control of the motivation to obtain nicotine is distinctly different from food reward, indicating the specificity of the underlying genetic mechanisms. |
2013-02-12 |
2023-08-12 |
human |
| Hao Chen, Katie A Hiler, Elizabeth A Tolley, Shannon G Matta, Burt M Shar. Genetic factors control nicotine self-administration in isogenic adolescent rat strains. PloS one. vol 7. issue 8. 2013-02-12. PMID:22937166. |
lastly, the behavior of f1 hybrids was not predicted from the additive behavior of the parental strains, indicating the impact of significant gene-gene interactions on the susceptibility to nicotine reward. |
2013-02-12 |
2023-08-12 |
human |
| Xiaomeng Xu, Jin Wang, Arthur Aron, Wei Lei, J Lee Westmaas, Xuchu Wen. Intense passionate love attenuates cigarette cue-reactivity in nicotine-deprived smokers: an FMRI study. PloS one. vol 7. issue 7. 2013-01-14. PMID:22860092. |
these results provide evidence that rewards from one domain (self-expansion) can act as a substitute for reward from another domain (nicotine) to attenuate cigarette cue reactivity. |
2013-01-14 |
2023-08-12 |
human |
| Ryan T Lacy, Lauren L Hord, Amanda J Morgan, Steven B Harro. Intravenous gestational nicotine exposure results in increased motivation for sucrose reward in adult rat offspring. Drug and alcohol dependence. vol 124. issue 3. 2012-12-10. PMID:22377090. |
intravenous gestational nicotine exposure results in increased motivation for sucrose reward in adult rat offspring. |
2012-12-10 |
2023-08-12 |
rat |
| Ryan T Lacy, Lauren L Hord, Amanda J Morgan, Steven B Harro. Intravenous gestational nicotine exposure results in increased motivation for sucrose reward in adult rat offspring. Drug and alcohol dependence. vol 124. issue 3. 2012-12-10. PMID:22377090. |
animal models show that gestational nicotine (gn) exposure mediates changes in responding for sucrose and drug reward. |
2012-12-10 |
2023-08-12 |
rat |
| Laura L Locklear, Craig G McDonald, Robert F Smith, Karl J Fryxel. Adult mice voluntarily progress to nicotine dependence in an oral self-selection assay. Neuropharmacology. vol 63. issue 4. 2012-11-30. PMID:22583831. |
however, high throughput models of nicotine reward have not been developed in mice. |
2012-11-30 |
2023-08-12 |
mouse |