| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vidya Narayanaswami, Sucharita S Somkuwar, David B Horton, Lisa A Cassis, Linda P Dwoski. Angiotensin AT1 and AT2 receptor antagonists modulate nicotine-evoked [³H]dopamine and [³H]norepinephrine release. Biochemical pharmacology. vol 86. issue 5. 2013-10-25. PMID:23831951. |
thus, angiotensin receptors contribute to the effects of nicotine on dopamine and norepinephrine release in brain regions involved in nicotine reward and hypertension. |
2013-10-25 |
2023-08-12 |
Not clear |
| Petra Suchankova, Elisabet Jerlhag, Nitya Jayaram-Lindström, Staffan Nilsson, Kjell Toren, Annika Rosengren, Jörgen A Engel, Johan Franc. Genetic variation of the ghrelin signalling system in individuals with amphetamine dependence. PloS one. vol 8. issue 4. 2013-10-22. PMID:23579732. |
ghrelin, an orexigenic peptide, activates the reward systems and is required for reward induced by alcohol, nicotine, cocaine and amphetamine in mice. |
2013-10-22 |
2023-08-12 |
mouse |
| Stephen Brimijoin, Xiaoyun Shen, Frank Orson, Thomas Koste. Prospects, promise and problems on the road to effective vaccines and related therapies for substance abuse. Expert review of vaccines. vol 12. issue 3. 2013-09-16. PMID:23496671. |
clinical trials of vaccines against cocaine and nicotine have been completed with the generally encouraging result that subjects showing high titers of antidrug antibody experience a reduction in drug reward, which may aid in cessation. |
2013-09-16 |
2023-08-12 |
human |
| Marla K Perna, Russell W Brow. Adolescent nicotine sensitization and effects of nicotine on accumbal dopamine release in a rodent model of increased dopamine D2 receptor sensitivity. Behavioural brain research. vol 242. 2013-08-27. PMID:23291224. |
this study reveals that neonatal quinpirole enhanced adolescent nicotine sensitization, accumbal dopamine overflow, and bdnf protein in response to nicotine, which may be related to changes in the brain's reward system. |
2013-08-27 |
2023-08-12 |
rat |
| J M Jansma, H H van Hell, L J M J Vanderschuren, M G Bossong, G Jager, R S Kahn, N F Ramse. THC reduces the anticipatory nucleus accumbens response to reward in subjects with a nicotine addiction. Translational psychiatry. vol 3. 2013-08-13. PMID:23443360. |
thc reduces the anticipatory nucleus accumbens response to reward in subjects with a nicotine addiction. |
2013-08-13 |
2023-08-12 |
human |
| J M Jansma, H H van Hell, L J M J Vanderschuren, M G Bossong, G Jager, R S Kahn, N F Ramse. THC reduces the anticipatory nucleus accumbens response to reward in subjects with a nicotine addiction. Translational psychiatry. vol 3. 2013-08-13. PMID:23443360. |
the ecb system also has an important role in reward mechanisms, and nicotine addiction has been associated with aberrant reward processing. |
2013-08-13 |
2023-08-12 |
human |
| J M Jansma, H H van Hell, L J M J Vanderschuren, M G Bossong, G Jager, R S Kahn, N F Ramse. THC reduces the anticipatory nucleus accumbens response to reward in subjects with a nicotine addiction. Translational psychiatry. vol 3. 2013-08-13. PMID:23443360. |
motivated by this evidence, we tested the hypothesis that ecb modulation of reward processing is altered in subjects with a nicotine addiction (nad). |
2013-08-13 |
2023-08-12 |
human |
| J M Jansma, H H van Hell, L J M J Vanderschuren, M G Bossong, G Jager, R S Kahn, N F Ramse. THC reduces the anticipatory nucleus accumbens response to reward in subjects with a nicotine addiction. Translational psychiatry. vol 3. 2013-08-13. PMID:23443360. |
these results suggest that nicotine addiction is associated with altered ecb modulation of reward processing in the nacc. |
2013-08-13 |
2023-08-12 |
human |
| Yvonne Paelecke-Habermann, Marko Paelecke, Katharina Giegerich, Katja Reschke, Andrea Küble. Implicit and explicit reward learning in chronic nicotine use. Drug and alcohol dependence. vol 129. issue 1-2. 2013-08-12. PMID:23098679. |
chronic tobacco use is related to specific neurobiological alterations in the dopaminergic brain reward system that can be termed "reward deficiency syndrome" in dependent nicotine consumers. |
2013-08-12 |
2023-08-12 |
Not clear |
| Cassandra D Gipson, Kathryn J Reissner, Yonatan M Kupchik, Alexander C W Smith, Neringa Stankeviciute, Megan E Hensley-Simon, Peter W Kaliva. Reinstatement of nicotine seeking is mediated by glutamatergic plasticity. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 22. 2013-07-30. PMID:23671067. |
nicotine, an active alkaloid in tobacco, is self-administered by animals and produces cellular adaptations in brain regions associated with drug reward, such as the nucleus accumbens. |
2013-07-30 |
2023-08-12 |
rat |
| Kanjana Suriyaprom, Rungsunn Tungtrongchitr, Talabporn Harnroongro. Impact of COMT Val 108/158 Met and DRD2 Taq1B gene polymorphisms on vulnerability to cigarette smoking of Thai males. Journal of molecular neuroscience : MN. vol 49. issue 3. 2013-07-25. PMID:22740151. |
the nicotine in cigarette smoke can stimulate the dopaminergic reward pathways. |
2013-07-25 |
2023-08-12 |
Not clear |
| Nii A Addy, Marina R Picciott. Nicotine, striatum, and reward. Biological psychiatry. vol 73. issue 3. 2013-06-28. PMID:23337022. |
nicotine, striatum, and reward. |
2013-06-28 |
2023-08-12 |
Not clear |
| Paul M Cinciripini, Jason D Robinson, Maher Karam-Hage, Jennifer A Minnix, Cho Lam, Francesco Versace, Victoria L Brown, Jeffrey M Engelmann, David W Wette. Effects of varenicline and bupropion sustained-release use plus intensive smoking cessation counseling on prolonged abstinence from smoking and on depression, negative affect, and other symptoms of nicotine withdrawal. JAMA psychiatry. vol 70. issue 5. 2013-06-27. PMID:23536105. |
given the actions of varenicline tartrate and bupropion hydrochloride sustained-release (sr) on neurobiological targets related to affect and reward, it is thought that the modulation of nicotine withdrawal symptoms may contribute to their effectiveness. |
2013-06-27 |
2023-08-12 |
Not clear |
| Kia J Jackson, Sarah S Sanjakdar, Xiangning Chen, M Imad Dama. Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice. PloS one. vol 7. issue 11. 2013-05-28. PMID:23226481. |
nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase iv knockout mice. |
2013-05-28 |
2023-08-12 |
mouse |
| Kia J Jackson, Sarah S Sanjakdar, Xiangning Chen, M Imad Dama. Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice. PloS one. vol 7. issue 11. 2013-05-28. PMID:23226481. |
using male camkiv genetically modified mice, we found that nicotine reward is attenuated in camkiv knockout (-/-) mice, but cocaine reward is enhanced in these mice. |
2013-05-28 |
2023-08-12 |
mouse |
| Kia J Jackson, Sarah S Sanjakdar, Xiangning Chen, M Imad Dama. Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice. PloS one. vol 7. issue 11. 2013-05-28. PMID:23226481. |
camkiv protein levels were also increased in the nucleus accumbens of c57bl/6 mice after nicotine reward. |
2013-05-28 |
2023-08-12 |
mouse |
| Kia J Jackson, Sarah S Sanjakdar, Xiangning Chen, M Imad Dama. Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice. PloS one. vol 7. issue 11. 2013-05-28. PMID:23226481. |
taken together, our results support an important role for camkiv in nicotine reward, and suggest that camkiv has opposing roles in nicotine and cocaine reward. |
2013-05-28 |
2023-08-12 |
mouse |
| Xiaojing Di, Jingqi Yan, Yan Zhao, Yanzhong Chang, Baolu Zha. L-theanine inhibits nicotine-induced dependence via regulation of the nicotine acetylcholine receptor-dopamine reward pathway. Science China. Life sciences. vol 55. issue 12. 2013-05-17. PMID:23233221. |
l-theanine inhibits nicotine-induced dependence via regulation of the nicotine acetylcholine receptor-dopamine reward pathway. |
2013-05-17 |
2023-08-12 |
mouse |
| Xiaojing Di, Jingqi Yan, Yan Zhao, Yanzhong Chang, Baolu Zha. L-theanine inhibits nicotine-induced dependence via regulation of the nicotine acetylcholine receptor-dopamine reward pathway. Science China. Life sciences. vol 55. issue 12. 2013-05-17. PMID:23233221. |
l-theanine treatment also reduced the upregulation of the α(4), β(2) and α(7) nicotine acetylcholine receptor (nachr) subunits induced by nicotine in mouse brain regions that related to the dopamine reward pathway, thus decreasing the number of cells that could react to nicotine. |
2013-05-17 |
2023-08-12 |
mouse |
| Scott T Barrett, Rick A Bevin. A quantitative analysis of the reward-enhancing effects of nicotine using reinforcer demand. Behavioural pharmacology. vol 23. issue 8. 2013-05-01. PMID:23080311. |
reward enhancement by nicotine has been suggested as an important phenomenon contributing toward tobacco abuse and dependence. |
2013-05-01 |
2023-08-12 |
human |