| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher G Ahnallen, Gabrielle I Liverant, Kristin L Gregor, Barbara W Kamholz, James J Levitt, Suzy Bird Gulliver, Diego A Pizzagalli, Vamsi K Koneru, Gary B Kapla. The relationship between reward-based learning and nicotine dependence in smokers with schizophrenia. Psychiatry research. vol 196. issue 1. 2012-07-24. PMID:22342123. |
impairments in the reward system may be related to elevated rates of nicotine dependence and lower cessation rates in this psychiatric group. |
2012-07-24 |
2023-08-12 |
Not clear |
| Christopher G Ahnallen, Gabrielle I Liverant, Kristin L Gregor, Barbara W Kamholz, James J Levitt, Suzy Bird Gulliver, Diego A Pizzagalli, Vamsi K Koneru, Gary B Kapla. The relationship between reward-based learning and nicotine dependence in smokers with schizophrenia. Psychiatry research. vol 196. issue 1. 2012-07-24. PMID:22342123. |
among sws, reduced reward responsiveness and increased anhedonia were associated with and may contribute to greater co-occurring nicotine dependence. |
2012-07-24 |
2023-08-12 |
Not clear |
| N S Pentkowski, M R Painter, K J Thiel, N A Peartree, T H C Cheung, P Deviche, M Adams, J Alba, J L Neisewande. Nicotine-induced plasma corticosterone is attenuated by social interactions in male and female adolescent rats. Pharmacology, biochemistry, and behavior. vol 100. issue 1. 2012-07-23. PMID:21782841. |
these findings suggest that the presence of a social partner may decrease the initial negative, stress-activating effects of nicotine, perhaps leading to increased nicotine reward. |
2012-07-23 |
2023-08-12 |
rat |
| Aryeh I Herman, Andrew J Waters, Sherry A McKee, Mehmet Sofuogl. Effects of pregabalin on smoking behavior, withdrawal symptoms, and cognitive performance in smokers. Psychopharmacology. vol 220. issue 3. 2012-07-11. PMID:21947318. |
in preclinical and clinical studies, medications enhancing the gaba neurotransmission attenuate nicotine reward. |
2012-07-11 |
2023-08-12 |
Not clear |
| Heidi Hartsto. The case for compulsive shopping as an addiction. Journal of psychoactive drugs. vol 44. issue 1. 2012-06-21. PMID:22641966. |
addictive drugs like cocaine, opiates and nicotine, through direct or indirect means, hyperstimulate the dopamine (da) reward system. |
2012-06-21 |
2023-08-12 |
Not clear |
| Henri-Jean Aubin, Amandine Luquiens, Patrick Dupont, Anne Borgn. [Current therapeutic strategies for tobacco dependence]. La Revue du praticien. vol 62. issue 3. 2012-05-31. PMID:22514987. |
the mechanisms of nicotine dependence are very similar to those of other addictive behaviors, and are based on disequilibrium of the meso-cortico-limbic reward system. |
2012-05-31 |
2023-08-12 |
Not clear |
| Christie D Fowler, Paul J Kenn. Intravenous nicotine self-administration and cue-induced reinstatement in mice: effects of nicotine dose, rate of drug infusion and prior instrumental training. Neuropharmacology. vol 61. issue 4. 2012-05-25. PMID:21640128. |
we found that stable responding for nicotine in c57bl6/j mice was facilitated by prior instrumental training for food reward, initial exposure of mice to a lower unit dose of nicotine (0.03 mg kg(-1) per infusion) before access to higher doses, a slower rate of drug delivery (3-s versus 1-s infusion), consistency in schedule of daily testing, and low extraneous noise during testing. |
2012-05-25 |
2023-08-12 |
mouse |
| Adrie W Bruijnzeel, Jenna Ford, Jessica A Rogers, Stacey Scheick, Yue Ji, Mahendra Bishnoi, Jon C Alexande. Blockade of CRF1 receptors in the central nucleus of the amygdala attenuates the dysphoria associated with nicotine withdrawal in rats. Pharmacology, biochemistry, and behavior. vol 101. issue 1. 2012-05-25. PMID:22182462. |
it was investigated if blockade of crf1 receptors, blockade of α1-adrenergic receptors, or stimulation of α2-adrenergic receptors in the cea diminishes the deficit in brain reward function associated with nicotine withdrawal in rats. |
2012-05-25 |
2023-08-12 |
rat |
| Adrie W Bruijnzeel, Jenna Ford, Jessica A Rogers, Stacey Scheick, Yue Ji, Mahendra Bishnoi, Jon C Alexande. Blockade of CRF1 receptors in the central nucleus of the amygdala attenuates the dysphoria associated with nicotine withdrawal in rats. Pharmacology, biochemistry, and behavior. vol 101. issue 1. 2012-05-25. PMID:22182462. |
in all the experiments, mecamylamine elevated the brain reward thresholds of the rats chronically treated with nicotine and did not affect the brain reward thresholds of the saline-treated control rats. |
2012-05-25 |
2023-08-12 |
rat |
| Adrie W Bruijnzeel, Jenna Ford, Jessica A Rogers, Stacey Scheick, Yue Ji, Mahendra Bishnoi, Jon C Alexande. Blockade of CRF1 receptors in the central nucleus of the amygdala attenuates the dysphoria associated with nicotine withdrawal in rats. Pharmacology, biochemistry, and behavior. vol 101. issue 1. 2012-05-25. PMID:22182462. |
intra-cea administration of the α1-adrenergic receptor antagonist prazosin or the α2-adrenergic receptor agonist clonidine did not affect the brain reward thresholds of the nicotine or saline-treated rats. |
2012-05-25 |
2023-08-12 |
rat |
| Amir Levine, Yanyou Huang, Bettina Drisaldi, Edmund A Griffin, Daniela D Pollak, Shiqin Xu, Deqi Yin, Christine Schaffran, Denise B Kandel, Eric R Kande. Molecular mechanism for a gateway drug: epigenetic changes initiated by nicotine prime gene expression by cocaine. Science translational medicine. vol 3. issue 107. 2012-05-17. PMID:22049069. |
we found that pretreatment of mice with nicotine increased the response to cocaine, as assessed by addiction-related behaviors and synaptic plasticity in the striatum, a brain region critical for addiction-related reward. |
2012-05-17 |
2023-08-12 |
mouse |
| Liwang Liu, Rubing Zhao-Shea, J Michael McIntosh, Paul D Gardner, Andrew R Tappe. Nicotine persistently activates ventral tegmental area dopaminergic neurons via nicotinic acetylcholine receptors containing α4 and α6 subunits. Molecular pharmacology. vol 81. issue 4. 2012-05-07. PMID:22222765. |
nicotine is reinforcing because it activates dopaminergic (daergic) neurons within the ventral tegmental area (vta) of the brain's mesocorticolimbic reward circuitry. |
2012-05-07 |
2023-08-12 |
mouse |
| Merideth A Addicott, David A A Baranger, Rachel V Kozink, Moria J Smoski, Gabriel S Dichter, F Joseph McClerno. Smoking withdrawal is associated with increases in brain activation during decision making and reward anticipation: a preliminary study. Psychopharmacology. vol 219. issue 2. 2012-05-01. PMID:21766170. |
acute nicotine abstinence is associated with disruption of executive function and reward processes; however, the neurobiological basis of these effects has not been fully elucidated. |
2012-05-01 |
2023-08-12 |
Not clear |
| Ting Chen, Die Zhang, Andrei Dragomir, Kunikazu Kobayashi, Yasemin Akay, Metin Aka. Investigating the influence of PFC transection and nicotine on dynamics of AMPA and NMDA receptors of VTA dopaminergic neurons. Journal of neuroengineering and rehabilitation. vol 8. 2012-04-05. PMID:22018308. |
all drugs of abuse, including nicotine, activate the mesocorticolimbic system that plays critical roles in nicotine reward and reinforcement development and triggers glutamatergic synaptic plasticity on the dopamine (da) neurons in the ventral tegmental area (vta). |
2012-04-05 |
2023-08-12 |
Not clear |
| Kia J Jackson, Xiangning Chen, Michael F Miles, JoLynne Harenza, M Imad Dama. The neuropeptide galanin and variants in the GalR1 gene are associated with nicotine dependence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 11. 2012-03-20. PMID:21796100. |
here, using mouse models of nicotine reward and withdrawal, we show that there is a significant correlation between mecamylamine-precipitated nicotine withdrawal somatic signs and basal galanin or galanin receptor 1 (galr1) expression in mesolimbocortical dopamine regions across the bxd battery of recombinant inbred mouse lines. |
2012-03-20 |
2023-08-12 |
mouse |
| Jeffrey S Smith, Abigail G Schindler, Emma Martinelli, Richard M Gustin, Michael R Bruchas, Charles Chavki. Stress-induced activation of the dynorphin/κ-opioid receptor system in the amygdala potentiates nicotine conditioned place preference. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 4. 2012-03-12. PMID:22279233. |
or by local injection in the amygdala (2.5 μg) without affecting nicotine reward in the absence of stress. |
2012-03-12 |
2023-08-12 |
mouse |
| Elisabet Jerlhag, Jörgen A Enge. Ghrelin receptor antagonism attenuates nicotine-induced locomotor stimulation, accumbal dopamine release and conditioned place preference in mice. Drug and alcohol dependence. vol 117. issue 2-3. 2012-02-06. PMID:21310553. |
as the target circuits for other drugs of abuse, including nicotine, in the brain includes this reward link, we sought to determine whether the central ghrelin signalling system is involved in nicotine's activation of this system. |
2012-02-06 |
2023-08-12 |
mouse |
| Maria Hadjiconstantinou, Norton H Nef. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:21108953. |
although the mesolimbic dopamine hypothesis is the most influential theory of nicotine reward and reinforcement, there has been a consensus that other neurotransmitter systems contribute to the addictive properties of nicotine as well. |
2012-01-18 |
2023-08-12 |
Not clear |
| Maria Hadjiconstantinou, Norton H Nef. Nicotine and endogenous opioids: neurochemical and pharmacological evidence. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:21108953. |
4) genetic and pharmacological studies indicate that μ-opioid (mopr) receptors are mainly involved in nicotine reward, while doprs contribute to the emotional and koprs to the aversive responses of nicotine. |
2012-01-18 |
2023-08-12 |
Not clear |
| Yu Jin, Kechun Yang, Hong Wang, Jie W. Exposure of nicotine to ventral tegmental area slices induces glutamatergic synaptic plasticity on dopamine neurons. Synapse (New York, N.Y.). vol 65. issue 4. 2011-12-20. PMID:20730803. |
nicotine promotes glutamatergic synaptic plasticity in dopaminergic (da) neurons in the ventral tegmental area (vta), which is thought to be an important mechanism underlying nicotine reward. |
2011-12-20 |
2023-08-12 |
mouse |