| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna M Lee, Robert O Messin. Protein kinase C epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 38. 2011-12-12. PMID:21911393. |
protein kinase c epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens. |
2011-12-12 |
2023-08-12 |
mouse |
| Anna M Lee, Robert O Messin. Protein kinase C epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 38. 2011-12-12. PMID:21911393. |
our results indicate that pkcε regulates reward signaling through α(6)-containing nicotinic receptors and suggest that pkcε could be a target for the treatment of comorbid nicotine and alcohol addictions. |
2011-12-12 |
2023-08-12 |
mouse |
| Qin Fang, Fang-Qiong Li, Yan-Qin Li, Yan-Xue Xue, Ying-Ying He, Jian-Feng Liu, Lin Lu, Ji-Shi Wan. Cannabinoid CB1 receptor antagonist rimonabant disrupts nicotine reward-associated memory in rats. Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21722663. |
based on previous findings, in which cannabinoid cb(1) receptors were found to be critically involved in specific aspects of learning and memory, we investigated the role of cb(1) receptors in nicotine reward memory using a rat conditioned place preference (cpp) model. |
2011-12-09 |
2023-08-12 |
rat |
| Qin Fang, Fang-Qiong Li, Yan-Qin Li, Yan-Xue Xue, Ying-Ying He, Jian-Feng Liu, Lin Lu, Ji-Shi Wan. Cannabinoid CB1 receptor antagonist rimonabant disrupts nicotine reward-associated memory in rats. Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21722663. |
to examine the effects of rimonabant on the reconsolidation of nicotine reward memory, rats were administered rimonabant (0, 0.3, and 3.0mg/kg, i.p.) |
2011-12-09 |
2023-08-12 |
rat |
| Qin Fang, Fang-Qiong Li, Yan-Qin Li, Yan-Xue Xue, Ying-Ying He, Jian-Feng Liu, Lin Lu, Ji-Shi Wan. Cannabinoid CB1 receptor antagonist rimonabant disrupts nicotine reward-associated memory in rats. Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21722663. |
to examine the effects of rimonabant on the reinstatement of nicotine reward memory, rimonabant (0, 0.3, and 3.0mg/kg, i.p.) |
2011-12-09 |
2023-08-12 |
rat |
| Qin Fang, Fang-Qiong Li, Yan-Qin Li, Yan-Xue Xue, Ying-Ying He, Jian-Feng Liu, Lin Lu, Ji-Shi Wan. Cannabinoid CB1 receptor antagonist rimonabant disrupts nicotine reward-associated memory in rats. Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21722663. |
these findings provide clear evidence that cb(1) receptors play a role in nicotine reward memory, suggesting that cb(1) receptor antagonists may be a potential target for managing nicotine addiction. |
2011-12-09 |
2023-08-12 |
rat |
| Hisatsugu Miyata, Michio Itasaka, Naofumi Kimura, Kazuhiko Nakayam. Decreases in brain reward function reflect nicotine- and methamphetamine-withdrawal aversion in rats. Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886564. |
the purpose of the present study was to investigate whether brain reward function decreases during withdrawal from nicotine and methamphetamine, and whether decreased reward function is related to aversion during withdrawal from these drugs. |
2011-11-10 |
2023-08-12 |
rat |
| Hisatsugu Miyata, Michio Itasaka, Naofumi Kimura, Kazuhiko Nakayam. Decreases in brain reward function reflect nicotine- and methamphetamine-withdrawal aversion in rats. Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886564. |
interestingly, elevations in icss reward thresholds and place aversion during mecamylamine-precipitated nicotine withdrawal were almost the same in magnitude as those observed during haloperidol-precipitated methamphetamine withdrawal. |
2011-11-10 |
2023-08-12 |
rat |
| Hisatsugu Miyata, Michio Itasaka, Naofumi Kimura, Kazuhiko Nakayam. Decreases in brain reward function reflect nicotine- and methamphetamine-withdrawal aversion in rats. Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886564. |
the present study indicates that 1) brain reward function decreased during nicotine and methamphetamine withdrawal, and 2) a decrease in reward function may reflect the negative affective state (aversion) during withdrawal from nicotine and methamphetamine. |
2011-11-10 |
2023-08-12 |
rat |
| Christine H Kapelewski, David J Vandenbergh, Laura C Klei. Effect of the monoamine oxidase inhibition on rewarding effects of nicotine in rodents. Current drug abuse reviews. vol 4. issue 2. 2011-11-08. PMID:21696345. |
overall, studies with rats and mice do suggest that mao plays a role in nicotine reward. |
2011-11-08 |
2023-08-12 |
mouse |
| Christine H Kapelewski, David J Vandenbergh, Laura C Klei. Effect of the monoamine oxidase inhibition on rewarding effects of nicotine in rodents. Current drug abuse reviews. vol 4. issue 2. 2011-11-08. PMID:21696345. |
future research is needed that builds on the available literature to map out the relationship between mao inhibition and nicotine reward. |
2011-11-08 |
2023-08-12 |
mouse |
| Mariella De Biasi, John A Dan. Reward, addiction, withdrawal to nicotine. Annual review of neuroscience. vol 34. 2011-10-25. PMID:21438686. |
reward, addiction, withdrawal to nicotine. |
2011-10-25 |
2023-08-12 |
Not clear |
| Mariella De Biasi, John A Dan. Reward, addiction, withdrawal to nicotine. Annual review of neuroscience. vol 34. 2011-10-25. PMID:21438686. |
thus, nicotine taps into diverse neural systems and an array of nicotinic acetylcholine receptor (nachr) subtypes to influence reward, addiction, and withdrawal. |
2011-10-25 |
2023-08-12 |
Not clear |
| Dena Kota, Sarah Sanjakdar, Michael J Marks, Omar Khabour, Karem Alzoubi, M Imad Dama. Exploring behavioral and molecular mechanisms of nicotine reward in adolescent mice. Biochemical pharmacology. vol 82. issue 8. 2011-10-21. PMID:21708139. |
exploring behavioral and molecular mechanisms of nicotine reward in adolescent mice. |
2011-10-21 |
2023-08-12 |
mouse |
| Dena Kota, Sarah Sanjakdar, Michael J Marks, Omar Khabour, Karem Alzoubi, M Imad Dama. Exploring behavioral and molecular mechanisms of nicotine reward in adolescent mice. Biochemical pharmacology. vol 82. issue 8. 2011-10-21. PMID:21708139. |
learning and memory involvement in nicotine reward was assessed in early adolescent (pnd 28-34) and adult (pnd 70+) male icr mice by conducting conditioning sessions of nicotine (0.5mg/kg) acquisition at varying time-spans, and evaluating extinction and reinstatement of nicotine preference using conditioned place preference. |
2011-10-21 |
2023-08-12 |
mouse |
| Dena Kota, Sarah Sanjakdar, Michael J Marks, Omar Khabour, Karem Alzoubi, M Imad Dama. Exploring behavioral and molecular mechanisms of nicotine reward in adolescent mice. Biochemical pharmacology. vol 82. issue 8. 2011-10-21. PMID:21708139. |
more sensitive assays may facilitate in understanding the mechanisms of nicotine reward in adolescent mice. |
2011-10-21 |
2023-08-12 |
mouse |
| Michael Paolini, Mariella De Bias. Mechanistic insights into nicotine withdrawal. Biochemical pharmacology. vol 82. issue 8. 2011-10-21. PMID:21782803. |
besides examining how nicotine usurps the endogenous reward system, we will discuss how the habenula is part of a circuit that plays a critical role in the aversive effects of high nicotine doses and nicotine withdrawal. |
2011-10-21 |
2023-08-12 |
Not clear |
| Megan A McVay, Amy L Copelan. Smoking cessation in peri- and postmenopausal women: a review. Experimental and clinical psychopharmacology. vol 19. issue 3. 2011-10-07. PMID:21480728. |
recent evidence suggests that estrogen level may be positively associated with nicotine reward, which may aid in the smoking cessation efforts of postmenopausal women while possibly contributing to worse outcomes in perimenopausal women. |
2011-10-07 |
2023-08-12 |
Not clear |
| Tresa M McGranahan, Natalie E Patzlaff, Sharon R Grady, Stephen F Heinemann, T K Booke. α4β2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 30. 2011-10-07. PMID:21795541. |
α4β2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief. |
2011-10-07 |
2023-08-12 |
mouse |
| Tresa M McGranahan, Natalie E Patzlaff, Sharon R Grady, Stephen F Heinemann, T K Booke. α4β2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 30. 2011-10-07. PMID:21795541. |
two behaviors central to nicotine dependence, reward and anxiety relief, were examined. |
2011-10-07 |
2023-08-12 |
mouse |