| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Manoranjan S D'Souza, Athina Marko. The "stop" and "go" of nicotine dependence: role of GABA and glutamate. Cold Spring Harbor perspectives in medicine. vol 3. issue 6. 2014-01-24. PMID:23732855. |
importantly, chronic nicotine exposure alters the function of brain reward systems, resulting in the development of a nicotine-dependent state. |
2014-01-24 |
2023-08-12 |
Not clear |
| Pedro Lorenzo Fernánde. [Treatment and prevention of tobacco addiction. Antinicotinic vaccine]. Anales de la Real Academia Nacional de Medicina. vol 129. issue 1. 2014-01-09. PMID:24294730. |
the addictive mechanism of nicotine is the stimulus of nicotinic cholinergic receptors at the mesolimbic areas of the brain, which in turn stimulate dopamine release in the brain centres of reward (mainly n. accumbens). |
2014-01-09 |
2023-08-12 |
Not clear |
| F Saint-Preux, L R Bores, I Tulloch, B Ladenheim, R Kim, P K Thanos, N D Volkow, J L Cade. Chronic co-administration of nicotine and methamphetamine causes differential expression of immediate early genes in the dorsal striatum and nucleus accumbens of rats. Neuroscience. vol 243. 2013-12-17. PMID:23562942. |
nicotine and methamphetamine (meth) cause addiction by triggering neuroplastic changes in brain reward pathways though they each engage distinct molecular targets (nicotine receptors and dopamine transporters respectively). |
2013-12-17 |
2023-08-12 |
rat |
| Jie Wu, Ming Gao, Jian-Xin Shen, Wei-Xing Shi, Andrew M Oster, Boris S Gutki. Cortical control of VTA function and influence on nicotine reward. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23933294. |
cortical control of vta function and influence on nicotine reward. |
2013-12-17 |
2023-08-12 |
Not clear |
| Jie Wu, Ming Gao, Jian-Xin Shen, Wei-Xing Shi, Andrew M Oster, Boris S Gutki. Cortical control of VTA function and influence on nicotine reward. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23933294. |
the elicited increase of da neuronal activity is thought to be an important mechanism for nicotine reward and subsequently the transition to addiction. |
2013-12-17 |
2023-08-12 |
Not clear |
| Jie Wu, Ming Gao, Jian-Xin Shen, Wei-Xing Shi, Andrew M Oster, Boris S Gutki. Cortical control of VTA function and influence on nicotine reward. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23933294. |
however, the current understanding of nicotine reward is based predominantly on the data accumulated from in vitro studies, often from vta slices. |
2013-12-17 |
2023-08-12 |
Not clear |
| Jie Wu, Ming Gao, Jian-Xin Shen, Wei-Xing Shi, Andrew M Oster, Boris S Gutki. Cortical control of VTA function and influence on nicotine reward. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23933294. |
building upon the existing knowledge acquired in vitro, it is now time to elucidate the integrated mechanisms of nicotinic reward on intact systems that are more relevant to understanding the action of nicotine or other addictive drugs. |
2013-12-17 |
2023-08-12 |
Not clear |
| Jie Wu, Ming Gao, Jian-Xin Shen, Wei-Xing Shi, Andrew M Oster, Boris S Gutki. Cortical control of VTA function and influence on nicotine reward. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23933294. |
in this review, we summarize recent studies that demonstrate the impact of prefrontal cortex (pfc) on the modulation of vta da neuronal function and nicotine reward. |
2013-12-17 |
2023-08-12 |
Not clear |
| Jie Wu, Ming Gao, Jian-Xin Shen, Wei-Xing Shi, Andrew M Oster, Boris S Gutki. Cortical control of VTA function and influence on nicotine reward. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23933294. |
based on existing evidence, we propose a new hypothesis that pfc-vta functional coupling serves as an integration mechanism for nicotine reward. |
2013-12-17 |
2023-08-12 |
Not clear |
| John E Kelsey, Anzela Niraul. Effects of acute and sub-chronic nicotine on impulsive choice in rats in a probabilistic delay-discounting task. Psychopharmacology. vol 227. issue 3. 2013-12-13. PMID:23340981. |
suggesting causality, nicotine injections in rats increase the choice for an immediate reward over a larger, delayed reward. |
2013-12-13 |
2023-08-12 |
rat |
| Michael J McCluskie, David C Pryde, David P Gervais, David R Stead, Ningli Zhang, Michelle Benoit, Karen Robertson, In-Jeong Kim, Tharsika Tharmanathan, James R Merson, Heather L Davi. Enhancing immunogenicity of a 3'aminomethylnicotine-DT-conjugate anti-nicotine vaccine with CpG adjuvant in mice and non-human primates. International immunopharmacology. vol 16. issue 1. 2013-12-03. PMID:23562759. |
anti-nicotine vaccines offer a novel mechanism of action whereby anti-nicotine antibodies (ab) in circulation prevent nicotine from entering the brain, thus avoiding the reward mechanisms that underpin nicotine addiction. |
2013-12-03 |
2023-08-12 |
mouse |
| Kia J Jackson, Sarah S Sanjakdar, Pretal P Muldoon, J Michael McIntosh, M Imad Dama. The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse. Neuropharmacology. vol 70. 2013-11-26. PMID:23416040. |
the α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse. |
2013-11-26 |
2023-08-12 |
mouse |
| Kia J Jackson, Sarah S Sanjakdar, Pretal P Muldoon, J Michael McIntosh, M Imad Dama. The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse. Neuropharmacology. vol 70. 2013-11-26. PMID:23416040. |
using the selective α3β4* nachr antagonist, α-conotoxin auib, we assessed the role of α3β4* nachrs in acute nicotine, nicotine reward, and physical and affective nicotine withdrawal. |
2013-11-26 |
2023-08-12 |
mouse |
| Kia J Jackson, Sarah S Sanjakdar, Pretal P Muldoon, J Michael McIntosh, M Imad Dama. The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse. Neuropharmacology. vol 70. 2013-11-26. PMID:23416040. |
because α5 has also been implicated in nicotine dependence behaviors in mice and can form functional receptors with α3β4*, we also evaluated the role of the α3β4α5* nachr subtype in nicotine reward and somatic nicotine withdrawal signs by blocking the α3β4* nachr subtype in α5 nachr knockout mice with auib. |
2013-11-26 |
2023-08-12 |
mouse |
| Kia J Jackson, Sarah S Sanjakdar, Pretal P Muldoon, J Michael McIntosh, M Imad Dama. The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse. Neuropharmacology. vol 70. 2013-11-26. PMID:23416040. |
auib had no significant effect on acute nicotine behaviors, but dose-dependently attenuated nicotine reward and physical withdrawal signs, with no significant effect in affective withdrawal measures. |
2013-11-26 |
2023-08-12 |
mouse |
| Kia J Jackson, Sarah S Sanjakdar, Pretal P Muldoon, J Michael McIntosh, M Imad Dama. The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse. Neuropharmacology. vol 70. 2013-11-26. PMID:23416040. |
interestingly, auib also attenuated nicotine reward and somatic signs in α5 nachr knockout mice. |
2013-11-26 |
2023-08-12 |
mouse |
| Kia J Jackson, Sarah S Sanjakdar, Pretal P Muldoon, J Michael McIntosh, M Imad Dama. The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse. Neuropharmacology. vol 70. 2013-11-26. PMID:23416040. |
this study shows that α3β4* nachrs mediate nicotine reward and physical nicotine withdrawal, but not acute nicotine behaviors or affective nicotine withdrawal signs in mice. |
2013-11-26 |
2023-08-12 |
mouse |
| Kia J Jackson, Sarah S Sanjakdar, Pretal P Muldoon, J Michael McIntosh, M Imad Dama. The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse. Neuropharmacology. vol 70. 2013-11-26. PMID:23416040. |
our findings suggest an important role for the α3β4* nachr subtype in nicotine reward and physical aspects of the nicotine withdrawal syndrome. |
2013-11-26 |
2023-08-12 |
mouse |
| Kathrin U Müller, Eva Mennigen, Stephan Ripke, Tobias Banaschewski, Gareth J Barker, Christian Büchel, Patricia Conrod, Mira Fauth-Bühler, Herta Flor, Hugh Garavan, Andreas Heinz, Claire Lawrence, Eva Loth, Karl Mann, Jean-Luc Martinot, Zdenka Pausova, Marcella Rietschel, Andreas Ströhle, Maren Struve, Bernadeta Walaszek, Gunter Schumann, Tomáš Paus, Michael N Smolk. Altered reward processing in adolescents with prenatal exposure to maternal cigarette smoking. JAMA psychiatry. vol 70. issue 8. 2013-11-14. PMID:23784668. |
animal studies indicate that prenatal exposure to nicotine alters the development of brain areas related to reward processing, which might be a risk factor for substance use and addiction later in life. |
2013-11-14 |
2023-08-12 |
Not clear |
| Matthew W Buczynski, Ilham Y Polis, Loren H Parson. The volitional nature of nicotine exposure alters anandamide and oleoylethanolamide levels in the ventral tegmental area. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 4. 2013-10-29. PMID:23169348. |
cannabinoid-1 receptors (cb(1)) have an important role in nicotine reward and their function is disrupted by chronic nicotine exposure, suggesting nicotine-induced alterations in endocannabinoid (ecb) signaling. |
2013-10-29 |
2023-08-12 |
Not clear |