| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel C Castro, Shannon L Cole, Kent C Berridg. Lateral hypothalamus, nucleus accumbens, and ventral pallidum roles in eating and hunger: interactions between homeostatic and reward circuitry. Frontiers in systems neuroscience. vol 9. 2015-06-30. PMID:26124708. |
the nac and vp play special roles in mediating the hedonic impact ("liking") and motivational incentive salience ("wanting") of food rewards, and their interactions with lh help permit regulatory hunger/satiety modulation of food motivation and reward. |
2015-06-30 |
2023-08-13 |
Not clear |
| Sara E Berger, Alexis T Baria, Marwan N Baliki, Ali Mansour, Kristi M Herrmann, Souraya Torbey, Lejian Huang, Elle L Parks, Thomas J Schnizter, A Vania Apkaria. Risky monetary behavior in chronic back pain is associated with altered modular connectivity of the nucleus accumbens. BMC research notes. vol 7. 2015-06-25. PMID:25331931. |
the nucleus accumbens (nac) has a well established role in reward processing. |
2015-06-25 |
2023-08-13 |
human |
| Sara E Berger, Alexis T Baria, Marwan N Baliki, Ali Mansour, Kristi M Herrmann, Souraya Torbey, Lejian Huang, Elle L Parks, Thomas J Schnizter, A Vania Apkaria. Risky monetary behavior in chronic back pain is associated with altered modular connectivity of the nucleus accumbens. BMC research notes. vol 7. 2015-06-25. PMID:25331931. |
pain patients are known to perform abnormally in reward-related tasks, which suggests an intriguing link between pain, nac connectivity, and reward behavior. |
2015-06-25 |
2023-08-13 |
human |
| Sara E Berger, Alexis T Baria, Marwan N Baliki, Ali Mansour, Kristi M Herrmann, Souraya Torbey, Lejian Huang, Elle L Parks, Thomas J Schnizter, A Vania Apkaria. Risky monetary behavior in chronic back pain is associated with altered modular connectivity of the nucleus accumbens. BMC research notes. vol 7. 2015-06-25. PMID:25331931. |
we then measured modular connectivity of each participants' nac with resting state functional mri to investigate how connectivity accounts for reward behavior in the presence and absence of pain. |
2015-06-25 |
2023-08-13 |
human |
| Michelle Lee, Toby R Manders, Sarah E Eberle, Chen Su, James D'amour, Runtao Yang, Hau Yueh Lin, Karl Deisseroth, Robert C Froemke, Jing Wan. Activation of corticostriatal circuitry relieves chronic neuropathic pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 13. 2015-06-19. PMID:25834050. |
a key output target for the pfc is the nucleus accumbens (nac), an important component of the reward circuitry. |
2015-06-19 |
2023-08-13 |
human |
| Ja Wook Koo, Mary Kay Lobo, Dipesh Chaudhury, Benoit Labonté, Allyson Friedman, Elizabeth Heller, Catherine Jensen Peña, Ming-Hu Han, Eric J Nestle. Loss of BDNF signaling in D1R-expressing NAc neurons enhances morphine reward by reducing GABA inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 11. 2015-06-15. PMID:24853771. |
loss of bdnf signaling in d1r-expressing nac neurons enhances morphine reward by reducing gaba inhibition. |
2015-06-15 |
2023-08-13 |
mouse |
| Ja Wook Koo, Mary Kay Lobo, Dipesh Chaudhury, Benoit Labonté, Allyson Friedman, Elizabeth Heller, Catherine Jensen Peña, Ming-Hu Han, Eric J Nestle. Loss of BDNF signaling in D1R-expressing NAc neurons enhances morphine reward by reducing GABA inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 11. 2015-06-15. PMID:24853771. |
furthermore, we found that gabaar antagonism in the nac enhances morphine reward and that morphine exposure decreases trkb expression as well as gabaergic activity in d1-type msns. |
2015-06-15 |
2023-08-13 |
mouse |
| Jian Feng, Ningyi Shao, Keith E Szulwach, Vincent Vialou, Jimmy Huynh, Chun Zhong, Thuc Le, Deveroux Ferguson, Michael E Cahill, Yujing Li, Ja Wook Koo, Efrain Ribeiro, Benoit Labonte, Benjamin M Laitman, David Estey, Victoria Stockman, Pamela Kennedy, Thomas Couroussé, Isaac Mensah, Gustavo Turecki, Kym F Faull, Guo-li Ming, Hongjun Song, Guoping Fan, Patrizia Casaccia, Li Shen, Peng Jin, Eric J Nestle. Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nature neuroscience. vol 18. issue 4. 2015-06-08. PMID:25774451. |
we found that ten-eleven translocation protein 1 (tet1) was downregulated in mouse nucleus accumbens (nac), a key brain reward structure, by repeated cocaine administration, which enhanced behavioral responses to cocaine. |
2015-06-08 |
2023-08-13 |
mouse |
| Praneeth Namburi, Anna Beyeler, Suzuko Yorozu, Gwendolyn G Calhoon, Sarah A Halbert, Romy Wichmann, Stephanie S Holden, Kim L Mertens, Melodi Anahtar, Ada C Felix-Ortiz, Ian R Wickersham, Jesse M Gray, Kay M Ty. A circuit mechanism for differentiating positive and negative associations. Nature. vol 520. issue 7549. 2015-05-27. PMID:25925480. |
here we show that bla neurons projecting to the nucleus accumbens (nac projectors) or the centromedial amygdala (cem projectors) undergo opposing synaptic changes following fear or reward conditioning. |
2015-05-27 |
2023-08-13 |
Not clear |
| Jun-Jun Wang, Wen-Qing Yao, Yue-Jun Chen, Lan Ma, Ye-Zheng Ta. [Neurons in NAc core and BLA are activated during cocaine context-associated reward memory retrieval in mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 66. issue 5. 2015-05-16. PMID:25332000. |
[neurons in nac core and bla are activated during cocaine context-associated reward memory retrieval in mice]. |
2015-05-16 |
2023-08-13 |
mouse |
| Jun-Jun Wang, Wen-Qing Yao, Yue-Jun Chen, Lan Ma, Ye-Zheng Ta. [Neurons in NAc core and BLA are activated during cocaine context-associated reward memory retrieval in mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 66. issue 5. 2015-05-16. PMID:25332000. |
the results showed that: neuronal c-fos, zif268 protein expression levels in nucleus accumbens (nac) core both were elevated in cocaine retrieval group compared with those in saline retrieval (control) group during cocaine context-associated reward memory retrieval. |
2015-05-16 |
2023-08-13 |
mouse |
| Jun-Jun Wang, Wen-Qing Yao, Yue-Jun Chen, Lan Ma, Ye-Zheng Ta. [Neurons in NAc core and BLA are activated during cocaine context-associated reward memory retrieval in mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 66. issue 5. 2015-05-16. PMID:25332000. |
thus, nac core and bla were activated during cocaine context-associated reward memory retrieval. |
2015-05-16 |
2023-08-13 |
mouse |
| Jun-Jun Wang, Wen-Qing Yao, Yue-Jun Chen, Lan Ma, Ye-Zheng Ta. [Neurons in NAc core and BLA are activated during cocaine context-associated reward memory retrieval in mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 66. issue 5. 2015-05-16. PMID:25332000. |
the results suggest that neurons that are activated in nac core and bla are crucial basis of cocaine context-associated reward memory. |
2015-05-16 |
2023-08-13 |
mouse |
| Sharanya M Kousik, Paul M Carvey, T Celeste Napie. Methamphetamine self-administration results in persistent dopaminergic pathology: implications for Parkinson's disease risk and reward-seeking. The European journal of neuroscience. vol 40. issue 4. 2015-05-11. PMID:24890790. |
ventral tegmental area (vta) and nucleus accumbens (nac)], critical for meth-induced reward, was also evaluated. |
2015-05-11 |
2023-08-13 |
rat |
| Deveroux Ferguson, Ningyi Shao, Elizabeth Heller, Jian Feng, Rachael Neve, Hee-Dae Kim, Tanessa Call, Samantha Magazu, Li Shen, Eric J Nestle. SIRT1-FOXO3a regulate cocaine actions in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 7. 2015-04-13. PMID:25698746. |
previous studies have shown that chronic cocaine administration induces sirt1, a class iii histone deacetylase, in the nucleus accumbens (nac), a key brain reward region, and that such induction influences the gene regulation and place conditioning effects of cocaine. |
2015-04-13 |
2023-08-13 |
mouse |
| J R Gugusheff, Z Y Ong, B S Muhlhausle. Naloxone treatment alters gene expression in the mesolimbic reward system in 'junk food' exposed offspring in a sex-specific manner but does not affect food preferences in adulthood. Physiology & behavior. vol 133. 2015-02-19. PMID:24727340. |
we measured mrna expression of key components of the reward pathway (mu-opioid receptor, proenkephalin, tyrosine hydroxylase, d1 and d2 receptors and the dopamine active transporter (dat)) in the nucleus accumbens (nac) and ventral tegmental area (vta) of the offspring of control and cafeteria fed (jf) dams at weaning and after a 10-day naloxone treatment post-weaning and determined food preferences in adulthood in the remaining offspring. |
2015-02-19 |
2023-08-13 |
Not clear |
| Sevasti Gaspari, Maria M Papachatzaki, Ja Wook Koo, Fiona B Carr, Maria-Efstratia Tsimpanouli, Eugenia Stergiou, Rosemary C Bagot, Deveroux Ferguson, Ezekiell Mouzon, Sumana Chakravarty, Karl Deisseroth, Mary Kay Lobo, Venetia Zachario. Nucleus accumbens-specific interventions in RGS9-2 activity modulate responses to morphine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 8. 2015-02-12. PMID:24561386. |
consistent with earlier behavioural findings from constitutive rgs9 knockout mice, we show that rgs9-2 actions in the nac modulate morphine reward and dependence. |
2015-02-12 |
2023-08-12 |
mouse |
| Johann du Hoffmann, Saleem M Nicol. Dopamine invigorates reward seeking by promoting cue-evoked excitation in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 43. 2015-01-23. PMID:25339748. |
nucleus accumbens (nac) dopamine is required for reward-predictive cues to activate vigorous reward seeking, but the underlying neural mechanism is unknown. |
2015-01-23 |
2023-08-13 |
rat |
| Johann du Hoffmann, Saleem M Nicol. Dopamine invigorates reward seeking by promoting cue-evoked excitation in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 43. 2015-01-23. PMID:25339748. |
we demonstrate that, in the nac of rats performing a discriminative stimulus task for sucrose reward, blockade of either d1 or d2 receptors selectively attenuates excitation, but not inhibition, evoked by reward-predictive cues. |
2015-01-23 |
2023-08-13 |
rat |
| Kimberly Kirkpatrick, Andrew T Marshall, Aaron P Smith, Juraj Koci, Yoonseong Par. Individual differences in impulsive and risky choice: effects of environmental rearing conditions. Behavioural brain research. vol 269. 2015-01-15. PMID:24769268. |
furthermore, serotonin and norepinephrine concentrations in the nac significantly correlated with incentive motivation and the timing of the reward delays within the choice tasks. |
2015-01-15 |
2023-08-13 |
rat |