| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Xu, Yingjie Lin, Ming Yu, Kuikui Zho. The nucleus accumbens in reward and aversion processing: insights and implications. Frontiers in behavioral neuroscience. vol 18. 2024-08-26. PMID:39184934. |
the nucleus accumbens (nac), a central component of the brain's reward circuitry, has been implicated in a wide range of behaviors and emotional states. |
2024-08-26 |
2024-08-28 |
Not clear |
| Ying Xu, Yingjie Lin, Ming Yu, Kuikui Zho. The nucleus accumbens in reward and aversion processing: insights and implications. Frontiers in behavioral neuroscience. vol 18. 2024-08-26. PMID:39184934. |
emerging evidence, primarily drawing from recent rodent studies, suggests that the function of the nac in reward and aversion processing is multifaceted. |
2024-08-26 |
2024-08-28 |
Not clear |
| Seulgi Lee, Haemi Choi, Min-Hyeon Park, Bumhee Par. Differential role of negative and positive parenting styles on resting-state brain networks in middle-aged adolescents. Journal of affective disorders. 2024-08-22. PMID:39173921. |
the negative parenting style displayed connections with fc within the reward system, particularly in the left nucleus accumbens (nac), showcasing links to multiple frontal regions. |
2024-08-22 |
2024-08-25 |
Not clear |
| Yurong Zou, Tong Yu, Liwen Zhu, Qing Xu, Yuhong Li, Juran Chen, Qianyi Luo, Hongjun Pen. Altered dynamic functional connectivity of nucleus accumbens subregions in major depressive disorder: The interactive of childhood trauma and diagnosis. Social cognitive and affective neuroscience. 2024-08-21. PMID:39167467. |
previous research has observed alterations in the reward circuitry centered around the nucleus accumbens (nac) in mdd patients. |
2024-08-21 |
2024-08-24 |
human |
| Paolo S D'Aquil. Licking microstructure in response to novel rewards, reward devaluation and dopamine antagonists: possible role of D1 and D2 medium spiny neurons in the nucleus accumbens. Neuroscience and biobehavioral reviews. 2024-08-19. PMID:39159734. |
evidence on the effect of dopamine d1 and d2-like antagonists and of manipulations of reward value on licking microstructure is reanalysed considering recent findings on the role of nucleus accumbens (nac) medium spiny neurons (msns) in the control of sugar intake. |
2024-08-19 |
2024-08-22 |
Not clear |
| Chenfeng Zhang, Redas Dulinskas, Christian Ineichen, Alexandra Greter, Hannes Sigrist, Yulong Li, Gregorio Alanis-Lobato, Bastian Hengerer, Christopher R Pryc. Chronic stress deficits in reward behaviour co-occur with low nucleus accumbens dopamine activity during reward anticipation specifically. Communications biology. vol 7. issue 1. 2024-08-09. PMID:39123076. |
imaging studies in human reward pathology indicate attenuated bold activity in nucleus accumbens (nac) coincident with reward anticipation but not reinforcement; potentially, this is dopamine (da) related. |
2024-08-09 |
2024-08-13 |
mouse |
| Chenfeng Zhang, Redas Dulinskas, Christian Ineichen, Alexandra Greter, Hannes Sigrist, Yulong Li, Gregorio Alanis-Lobato, Bastian Hengerer, Christopher R Pryc. Chronic stress deficits in reward behaviour co-occur with low nucleus accumbens dopamine activity during reward anticipation specifically. Communications biology. vol 7. issue 1. 2024-08-09. PMID:39123076. |
therefore, in css mice, low nac da activity co-occurs with low reward anticipation and could account for deficits in learning and motivation, with important implications for understanding human reward pathology. |
2024-08-09 |
2024-08-13 |
mouse |
| María C Gutiérrez, María C Perondi, Gisella L Tortoni, Andrea B Cragnolini, Gabriel R Cuadra, Analía Valdomer. Early protein restriction in rats induces anhedonia in adult offspring: a key role of BDNF-TrkB signaling in the nucleus accumbens shell. Neuropharmacology. 2024-08-04. PMID:39098656. |
furthermore, perinatal protein-restriction-induced anhedonia correlated with increased bdnf and p-trkb protein levels in the nac, a core structure in the reward circuit linked with anhedonia. |
2024-08-04 |
2024-08-07 |
rat |
| Stuart J McDougall, Zhi Yi Ong, Rosa Heller, Anna Horton, Kimberly K Thek, Eun A Choi, Gavan P McNally, Andrew J Lawrenc. Viscerosensory signalling to the nucleus accumbens via the solitary tract nucleus. Journal of neurochemistry. 2024-07-20. PMID:39032068. |
as nts th neurons are the primary source for nac noradrenaline, we measured noradrenaline release in the nac and showed that nac noradrenaline levels declined in response to cue-induced reward retrieval but not foot shock. |
2024-07-20 |
2024-07-24 |
mouse |
| Freddyson J Martínez-Rivera, Yun Young Yim, Arthur Godino, Angélica Minier-Toribio, Solange Tofani, Leanne M Holt, Angélica Torres-Berrío, Rita Futamura, Caleb J Browne, Tamara Markovic, Peter J Hamilton, Rachael L Neve, Eric J Nestle. Cell-Type-Specific Regulation of Cocaine Reward by the E2F3a Transcription Factor in Nucleus Accumbens. bioRxiv : the preprint server for biology. 2024-07-19. PMID:39026727. |
these neurobiological processes in brain reward regions, such as the nucleus accumbens (nac), are orchestrated in large part by transcriptional regulation. |
2024-07-19 |
2024-07-21 |
mouse |
| Heather C Aziz, Regina A Mangier. Sex differences in membrane properties and cellular excitability of dopamine D1 receptor-expressing neurons within the shell of the nucleus accumbens of pre- and mid-adolescent mice. Biology of sex differences. vol 15. issue 1. 2024-07-13. PMID:39003495. |
the nucleus accumbens (nac), a striatal brain region composed of the core (nacc) and shell (nacsh), has been linked to risk-taking behavior and implicated in reward seeking and evaluation. |
2024-07-13 |
2024-07-16 |
mouse |
| Kimberly L P Long, Nerissa E G Hoglen, Alex J Keip, Robert M Klinkel, DéJenaé L See, Joseph Maa, Jenna C Wong, Michael Sherman, Devanand S Manol. Oxytocin receptor function regulates neural signatures of pair bonding and fidelity in the nucleus accumbens. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979148. |
signaling via the oxytocin receptor (oxtr) in the nucleus accumbens (nac) facilitates social reward as well as pair bond formation between mates in socially monogamous prairie voles |
2024-07-09 |
2024-07-12 |
Not clear |
| Nur Abdel-Hay, Marina Kabirova, Rami Yak. A discrete subpopulation of PFC-LHb neurons govern cocaine place preference. Translational psychiatry. vol 14. issue 1. 2024-07-02. PMID:38956048. |
the pfc interacts with the brain's reward system, including the ventral tegmental area (vta) and nucleus accumbens (nac). |
2024-07-02 |
2024-07-06 |
Not clear |
| Kasey L Brida, Emily T Jorgensen, Robert A Phillips, Catherine E Newman, Jennifer J Tuscher, Emily K Morring, Morgan E Zipperly, Lara Ianov, Kelsey D Montgomery, Madhavi Tippani, Thomas M Hyde, Kristen R Maynard, Keri Martinowich, Jeremy J Da. Reelin marks cocaine-activated striatal ensembles, promotes neuronal excitability, and regulates cocaine reward. bioRxiv : the preprint server for biology. 2024-07-01. PMID:38948801. |
drugs of abuse activate defined neuronal ensembles in brain reward structures such as the nucleus accumbens (nac), which are thought to promote the enduring synaptic, circuit, and behavioral consequences of drug exposure. |
2024-07-01 |
2024-07-03 |
Not clear |
| Sydney E Ashton, Paul Sharalla, Naru Kang, Adam T Brockett, Margaret M McCarthy, Matthew R Roesc. Distinct action signals by subregions in nucleus accumbens during STOP-change performance. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-06-19. PMID:38897724. |
nucleus accumbens (nac) is thought to contribute to motivated behavior by signaling the value of reward-predicting cues and the delivery of anticipated reward. |
2024-06-19 |
2024-06-22 |
rat |
| Sydney E Ashton, Paul Sharalla, Naru Kang, Adam T Brockett, Margaret M McCarthy, Matthew R Roesc. Distinct action signals by subregions in nucleus accumbens during STOP-change performance. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-06-19. PMID:38897724. |
while there are various and numerous theories of functions pertaining to these subregions and cell types, most are in the context of reward processing, with fewer considering that nac might serve functions related to action selection more generally. |
2024-06-19 |
2024-06-22 |
rat |
| Brandon Taraku, Joana R Loureiro, Ashish K Sahib, Artemis Zavaliangos-Petropulu, Noor Al-Sharif, Amber M Leaver, Benjamin Wade, Shantanu Joshi, Roger P Woods, Randall Espinoza, Katherine L Nar. Modulation of habenular and nucleus accumbens functional connectivity by ketamine in major depression. Brain and behavior. vol 14. issue 6. 2024-06-19. PMID:38894648. |
major depressive disorder (mdd) is associated with dysfunctional reward processing, which involves functional circuitry of the habenula (hb) and nucleus accumbens (nac). |
2024-06-19 |
2024-06-21 |
Not clear |
| Young-Jung Kim, Su Jeong Choi, Sa-Ik Hong, Jung-Cheol Park, Youyoung Lee, Shi-Xun Ma, Kwang-Hyun Hur, Young Lee, Kyeong-Man Kim, Hyung Kyu Kim, Hee Young Kim, Seok-Yong Lee, Se-Young Choi, Choon-Gon Jan. The ion channel TRPA1 is a modulator of the cocaine reward circuit in the nucleus accumbens. Molecular psychiatry. 2024-05-31. PMID:38822069. |
because the connection between pleasure and drug use becomes hard-wired in the nucleus accumbens (nac), which interfaces motivation, effective therapies need to modulate this mesolimbic reward system. |
2024-05-31 |
2024-06-02 |
mouse |
| Devin P Hagarty, Adam Dawoud, Alfonso Brea Guerrero, Kaynas Phillips, Caroline E Strong, Sarah Dollie Jennings, Michelle Crawford, Katherine Martinez, Olivia Csernecky, Samantha K Saland, Mohamed Kabba. Exploring Ketamine's Reinforcement, Cue-Induced Reinstatement, and Nucleus Accumbens cFos Activation in Male and Female Long Evans Rats. Neuropharmacology. 2024-05-26. PMID:38797243. |
neuronal activation was assessed using the protein expression of the immediate early gene cfos in the nucleus accumbens (nac), an important brain area implicated in reward, reinforcement and reinstatement to most drug-related cues. |
2024-05-28 |
2024-05-31 |
rat |
| Devin P Hagarty, Adam Dawoud, Alfonso Brea Guerrero, Kaynas Phillips, Caroline E Strong, Sarah Dollie Jennings, Michelle Crawford, Katherine Martinez, Olivia Csernecky, Samantha K Saland, Mohamed Kabba. Exploring Ketamine's Reinforcement, Cue-Induced Reinstatement, and Nucleus Accumbens cFos Activation in Male and Female Long Evans Rats. Neuropharmacology. 2024-05-26. PMID:38797243. |
neuronal activation was assessed using the protein expression of the immediate early gene cfos in the nucleus accumbens (nac), an important brain area implicated in reward, reinforcement and reinstatement to most drug-related cues. |
2024-05-26 |
2024-05-31 |
rat |