| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sigal Meilin, Fausto Machicao, Martin Elmlinge. Treatment with Actovegin improves spatial learning and memory in rats following transient forebrain ischaemia. Journal of cellular and molecular medicine. vol 18. issue 8. 2015-10-15. PMID:24797227. |
in rats, actovegin treatment improves spatial learning and memory following cerebral ischaemia, which may be related to hippocampal ca1 neuroprotection. |
2015-10-15 |
2023-08-13 |
rat |
| Roman Tashev, Margarita Stefanov. Hippocampal asymmetry in angiotensin II modulatory effects on learning and memory in rats. Acta neurobiologiae experimentalis. vol 75. issue 1. 2015-09-16. PMID:25856522. |
learning and memory effects of angiotensin ii (ang ii) microinjected unilaterally (left or right) and bilaterally into hippocampal ca1 area on the background of the inhibited hippocampal angiotensin 1 receptors type (at1) of male wistar rats were studied. |
2015-09-16 |
2023-08-13 |
rat |
| Roman Tashev, Margarita Stefanov. Hippocampal asymmetry in angiotensin II modulatory effects on learning and memory in rats. Acta neurobiologiae experimentalis. vol 75. issue 1. 2015-09-16. PMID:25856522. |
it was found that the combination (losartan 100 micrograms + ang ii 0.5 micrograms) microinjected bilaterally or into the left ca1 area improved learning and memory in shuttle-box and step through behavioral tests as compared to the respective controls. |
2015-09-16 |
2023-08-13 |
rat |
| Roman Tashev, Margarita Stefanov. Hippocampal asymmetry in angiotensin II modulatory effects on learning and memory in rats. Acta neurobiologiae experimentalis. vol 75. issue 1. 2015-09-16. PMID:25856522. |
the results point to a differential distribution of angiotensin ii receptors modulating the learning and memory processes in the left and right hippocampal ca1 area. |
2015-09-16 |
2023-08-13 |
rat |
| Hui-Yun Yang, Yang Liu, Jia-Cun Xie, Nan-Nan Liu, Xin Tia. Effects of repetitive transcranial magnetic stimulation on synaptic plasticity and apoptosis in vascular dementia rats. Behavioural brain research. vol 281. 2015-08-31. PMID:25541037. |
following establishment of a vad rat model using two-vessel occlusion (2vo), learning and memory were evaluated via the morris water maze (mwm), hippocampal ca1 neuron ultrastructure was examined via electron microscopy, and hippocampal synaptic plasticity was assessed by long-term potentiation (ltp). |
2015-08-31 |
2023-08-13 |
rat |
| Mei Zhou, Pan Luo, Yun Lu, Chang-jun Li, Dian-shi Wang, Qing Lu, Xu-lin Xu, Zhi He, Lian-jun Gu. Imbalance of HCN1 and HCN2 expression in hippocampal CA1 area impairs spatial learning and memory in rats with chronic morphine exposure. Progress in neuro-psychopharmacology & biological psychiatry. vol 56. 2015-07-31. PMID:25301101. |
imbalance of hcn1 and hcn2 expression in hippocampal ca1 area impairs spatial learning and memory in rats with chronic morphine exposure. |
2015-07-31 |
2023-08-13 |
rat |
| Mei Zhou, Pan Luo, Yun Lu, Chang-jun Li, Dian-shi Wang, Qing Lu, Xu-lin Xu, Zhi He, Lian-jun Gu. Imbalance of HCN1 and HCN2 expression in hippocampal CA1 area impairs spatial learning and memory in rats with chronic morphine exposure. Progress in neuro-psychopharmacology & biological psychiatry. vol 56. 2015-07-31. PMID:25301101. |
we found that chronic morphine exposure (5 mg/kg, sc, for 7 days) caused an inhibition of long-term potentiation (ltp) and impairment of spatial learning and memory, which is associated with a decrease in hcn1, and an increase in hcn2 on cell membrane of hippocampal ca1 area. |
2015-07-31 |
2023-08-13 |
rat |
| Carlos Santos-Filho, Camila M de Lima, César A R Fôro, Marcus A de Oliveira, Nara G M Magalhães, Cristovam Guerreiro-Diniz, Daniel G Diniz, Pedro F da C Vasconcelos, Cristovam W P Dini. Visuospatial learning and memory in the Cebus apella and microglial morphology in the molecular layer of the dentate gyrus and CA1 lacunosum molecular layer. Journal of chemical neuroanatomy. vol 61-62. 2015-07-31. PMID:25462387. |
visuospatial learning and memory in the cebus apella and microglial morphology in the molecular layer of the dentate gyrus and ca1 lacunosum molecular layer. |
2015-07-31 |
2023-08-13 |
monkey |
| Carlos Santos-Filho, Camila M de Lima, César A R Fôro, Marcus A de Oliveira, Nara G M Magalhães, Cristovam Guerreiro-Diniz, Daniel G Diniz, Pedro F da C Vasconcelos, Cristovam W P Dini. Visuospatial learning and memory in the Cebus apella and microglial morphology in the molecular layer of the dentate gyrus and CA1 lacunosum molecular layer. Journal of chemical neuroanatomy. vol 61-62. 2015-07-31. PMID:25462387. |
we investigated whether the morphology of microglia in the molecular layer of the dentate gyrus (dg-mol) or in the lacunosum molecular layer of ca1 (ca1-lmol) was correlated with spatial learning and memory in the capuchin monkey (cebus apella). |
2015-07-31 |
2023-08-13 |
monkey |
| Hong-Feng Gu, Ya-Xiong Nie, Qiao-Zhen Tong, Ya-Ling Tang, Yang Zeng, Kai-Quan Jing, Xi-Long Zheng, Duan-Fang Lia. Epigallocatechin-3-gallate attenuates impairment of learning and memory in chronic unpredictable mild stress-treated rats by restoring hippocampal autophagic flux. PloS one. vol 9. issue 11. 2015-07-06. PMID:25393306. |
taken together, these findings suggest that the impaired autophagy in ca1 regions of cums rats may contribute to learning and memory impairment. |
2015-07-06 |
2023-08-13 |
rat |
| Wei Jin, Yanqiu Jia, Lining Huang, Tianjun Wang, Hebo Wang, Yanhong Dong, Hezhen Zhang, Mingyue Fan, Peiyuan L. Lipoxin A4 methyl ester ameliorates cognitive deficits induced by chronic cerebral hypoperfusion through activating ERK/Nrf2 signaling pathway in rats. Pharmacology, biochemistry, and behavior. vol 124. 2015-05-19. PMID:24909072. |
lxa4 me significantly alleviated spatial learning and memory impairments, as assessed by morris water maze and inhibited the loss of neurons in the ca1 region of the hippocampus. |
2015-05-19 |
2023-08-13 |
rat |
| Taryn G Aubrecht, Richelle Jenkins, Ulysses J Magalang, Randy J Nelso. Influence of gonadal hormones on the behavioral effects of intermittent hypoxia in mice. American journal of physiology. Regulatory, integrative and comparative physiology. vol 308. issue 6. 2015-05-14. PMID:25552660. |
learning and memory changes were mirrored by changes in basilar dendritic length of the ca1 region of the hippocampus. |
2015-05-14 |
2023-08-13 |
mouse |
| Bruce C Harland, David A Collings, Neil McNaughton, Wickliffe C Abraham, John C Dalrymple-Alfor. Anterior thalamic lesions reduce spine density in both hippocampal CA1 and retrosplenial cortex, but enrichment rescues CA1 spines only. Hippocampus. vol 24. issue 10. 2015-05-12. PMID:24862603. |
comparison with enriched rats that received pseudo-training, which provided comparable task-related experience, but no explicit spatial memory training, suggested that basal ca1 spine density in particular was associated with spatial learning and memory performance. |
2015-05-12 |
2023-08-13 |
rat |
| Sònia Abad, Alberto Fole, Nuria del Olmo, David Pubill, Mercè Pallàs, Fèlix Junyent, Jorge Camarasa, Antonio Camins, Elena Escubed. MDMA enhances hippocampal-dependent learning and memory under restrictive conditions, and modifies hippocampal spine density. Psychopharmacology. vol 231. issue 5. 2015-02-19. PMID:24158501. |
the aim of this study was to investigate the impact of chronic mdma exposure on pyramidal neurons in the ca1 region of hippocampus and drug-related spatial learning and memory changes. |
2015-02-19 |
2023-08-12 |
Not clear |
| Su-Su Tang, Miao-jin Ji, Lan Chen, Mei Hu, Yan Long, Yong-qi Li, Ming-xing Miao, Jia-chang Li, Ning Li, Hui Ji, Xi-jing Chen, Hao Hon. Protective effect of pranlukast on Aβ₁₋₄₂-induced cognitive deficits associated with downregulation of cysteinyl leukotriene receptor 1. The international journal of neuropsychopharmacology. vol 17. issue 4. 2015-02-12. PMID:24229499. |
we found that bilateral intrahippocampal injection of aβ₁₋₄₂ resulted in a significant decline of spatial learning and memory of mice in the morris water maze (mwm) and y-maze tests, together with a serious depression of in vivo hippocampal long-term potentiation (ltp) in the ca1 region of the mice. |
2015-02-12 |
2023-08-12 |
mouse |
| Marina Mikhaylova, Anna Karpova, Julia Bär, Philipp Bethge, PingAn YuanXiang, Ying Chen, Werner Zuschratter, Thomas Behnisch, Michael R Kreut. Cellular distribution of the NMDA-receptor activated synapto-nuclear messenger Jacob in the rat brain. Brain structure & function. vol 219. issue 3. 2015-02-04. PMID:23539133. |
however, the protein also translocates to the nucleus in ca1 neurons after schaffer collateral long-term potentiation (ltp) but not long-term depression (ltd), suggesting that jacob might be involved in hippocampal and ltp-dependent learning and memory processes. |
2015-02-04 |
2023-08-12 |
rat |
| Ji Wang, Min Zhou, Xiaobin Wang, Xiaoling Yang, Maohua Wang, Chunxiang Zhang, Shuzhi Zhou, Ni Tan. Impact of ketamine on learning and memory function, neuronal apoptosis and its potential association with miR-214 and PTEN in adolescent rats. PloS one. vol 9. issue 6. 2015-01-29. PMID:24914689. |
ketamine administered to the adolescent rats at a dose of 80 mg/kg rather than the lower dose of 30 mg/kg caused learning and memory impairment, increased the number of apoptotic cells in the hippocampal ca1 region, cerebral cortex and subcortical region, decreased the mir-214 levels and increased pten protein expression in hippocampus. |
2015-01-29 |
2023-08-13 |
rat |
| Anne L Lardne. Neurobiological effects of the green tea constituent theanine and its potential role in the treatment of psychiatric and neurodegenerative disorders. Nutritional neuroscience. vol 17. issue 4. 2015-01-22. PMID:23883567. |
theanine also elicits improvements in cognitive function including learning and memory, in human and animal studies, possibly via a decrease in nmda-dependent ca1 long-term potentiation (ltp) and increase in nmda-independent ca1-ltp. |
2015-01-22 |
2023-08-12 |
human |
| Yifan He, Jihong Zhu, Fang Huang, Liu Qin, Wenguo Fan, Hongwen H. Age-dependent loss of cholinergic neurons in learning and memory-related brain regions and impaired learning in SAMP8 mice with trigeminal nerve damage. Neural regeneration research. vol 9. issue 22. 2015-01-19. PMID:25598781. |
in the elderly group, animals that underwent nerve transection had fewer pyramidal neurons in the hippocampal ca1 and ca3 regions, fewer cholinergic fibers in the ca1 and dentate gyrus, and fewer cholinergic neurons in the medial septal nucleus and vertical limb of the diagonal band, compared with sham-operated animals, as well as showing impairments in learning and memory. |
2015-01-19 |
2023-08-13 |
mouse |
| Bin Lu, Zhao Ma, Fei Cheng, Yan Zhao, Xin Zhang, Huijuan Mao, Xueyong Shen, Sheng Li. Effects of electroacupuncture on ethanol-induced impairments of spatial learning and memory and Fos expression in the hippocampus in rats. Neuroscience letters. vol 576. 2015-01-05. PMID:24923763. |
altogether, these results suggest that ea protects against ethanol-induced impairments of spatial learning and memory, which may be involved in the hippocampal ca1 area. |
2015-01-05 |
2023-08-13 |
rat |