| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hideaki Nishie, Ryouhei Miyata, Ryu Fujikawa, Ken-ichi Kinoshita, Yoshikage Muroi, Toshiaki Ishi. Post-weaning mice fed exclusively milk have deficits in induction of long-term depression in the CA1 hippocampal region and spatial learning and memory. Neuroscience research. vol 73. issue 4. 2012-11-13. PMID:22633993. |
post-weaning mice fed exclusively milk have deficits in induction of long-term depression in the ca1 hippocampal region and spatial learning and memory. |
2012-11-13 |
2023-08-12 |
mouse |
| Hideaki Nishie, Ryouhei Miyata, Ryu Fujikawa, Ken-ichi Kinoshita, Yoshikage Muroi, Toshiaki Ishi. Post-weaning mice fed exclusively milk have deficits in induction of long-term depression in the CA1 hippocampal region and spatial learning and memory. Neuroscience research. vol 73. issue 4. 2012-11-13. PMID:22633993. |
these result suggest that an exclusively milk formula diet after weaning leads to a stimulation of hippocampal neurogenesis but causes deficits in the induction of ltd in the ca1 hippocampal region and impairment of spatial learning and memory. |
2012-11-13 |
2023-08-12 |
mouse |
| Guangyu Li, Fei Cai, Wei Yan, Cairong Li, Jianghua Wan. A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease. Toxicological sciences : an official journal of the Society of Toxicology. vol 127. issue 2. 2012-09-24. PMID:22430071. |
this was found to lead to impairment of learning and memory, accompanied by severe histological damage and neuronal apoptosis in the hippocampal ca1 regions of rats. |
2012-09-24 |
2023-08-12 |
rat |
| Do Young Kim, Junwei Hao, Ruolan Liu, Gregory Turner, Fu-Dong Shi, Jong M Rh. Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis. PloS one. vol 7. issue 5. 2012-09-17. PMID:22567104. |
the kd improved motor disability in the eae model, as well as ca1 hippocampal synaptic plasticity (long-term potentiation) and spatial learning and memory (assessed with the morris water maze). |
2012-09-17 |
2023-08-12 |
mouse |
| Jing Feng, Qi Wu, Dan Zhang, Bao-yuan Che. Hippocampal impairments are associated with intermittent hypoxia of obstructive sleep apnea. Chinese medical journal. vol 125. issue 4. 2012-08-03. PMID:22490498. |
cellular damage to the hippocampal cornuammonis 1 (ca1) region likely contributes to neuropsychological impairment among osa patients, since neural circuits in the hippocampus are important in learning and memory. |
2012-08-03 |
2023-08-12 |
Not clear |
| Jose R Casanova, Masataka Nishimura, James W Owens, John W Swan. Impact of seizures on developing dendrites: implications for intellectual developmental disabilities. Epilepsia. vol 53 Suppl 1. 2012-07-16. PMID:22612816. |
however, by preventing the normal growth of dendrites, there is a reduction in ca1 glutamatergic synapses that supports long-lasting forms of synaptic plasticity thought to be the cellular basis of learning and memory. |
2012-07-16 |
2023-08-12 |
Not clear |
| Patrick M Kanju, Kodeeswaran Parameshwaran, Catrina Sims-Robinson, Subramaniam Uthayathas, Eleanor M Josephson, Nagalingam Rajakumar, Muralikrishnan Dhanasekaran, Vishnu Suppiramania. Selective cholinergic depletion in medial septum leads to impaired long term potentiation and glutamatergic synaptic currents in the hippocampus. PloS one. vol 7. issue 2. 2012-06-18. PMID:22355337. |
our results suggest that ms cholinergic afferents modulate ltp and glutamatergic currents in the ca1 region of the hippocampus, providing a potential synaptic mechanism for the learning and memory deficits observed in the rodent model of selective ms cholinergic lesioning. |
2012-06-18 |
2023-08-12 |
rat |
| Masataka Nishimura, Xue Gu, John W Swan. Seizures in early life suppress hippocampal dendrite growth while impairing spatial learning. Neurobiology of disease. vol 44. issue 2. 2012-06-11. PMID:21777677. |
experiments reported here explore these ideas by examining the effects of seizures in infant mice on learning and memory and on the growth of ca1 hippocampal pyramidal cell dendrites. |
2012-06-11 |
2023-08-12 |
mouse |
| Munder Zagaar, Ibrahim Alhaider, An Dao, Amber Levine, Ahmed Alkarawi, Mariam Alzubaidy, Karim Alkadh. The beneficial effects of regular exercise on cognition in REM sleep deprivation: behavioral, electrophysiological and molecular evidence. Neurobiology of disease. vol 45. issue 3. 2012-06-07. PMID:22227452. |
we examined the impact of 4 weeks of regular treadmill exercise on sleep deprivation induced spatial learning and memory, synaptic plasticity and related signaling molecules in area ca1 of the rat hippocampus. |
2012-06-07 |
2023-08-12 |
rat |
| Theodore C Duma. Postnatal alterations in induction threshold and expression magnitude of long-term potentiation and long-term depression at hippocampal synapses. Hippocampus. vol 22. issue 2. 2012-05-14. PMID:21069779. |
to assess possible relationships between modifications in synaptic plasticity and maturation of cognitive ability, we examined excitatory synaptic function in area ca1 of the mouse hippocampus ∼3 weeks of age, when hippocampal-dependent learning and memory abilities first emerge. |
2012-05-14 |
2023-08-12 |
mouse |
| Maria J Diógenes, Ana R Costenla, Luísa V Lopes, André Jerónimo-Santos, Vasco C Sousa, Bruno M Fontinha, Joaquim A Ribeiro, Ana M Sebastiã. Enhancement of LTP in aged rats is dependent on endogenous BDNF. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 9. 2012-05-08. PMID:21525862. |
the magnitude of ca1 ltp induced by a weak θ-burst stimuli delivered to the schaffer collaterals was significantly higher in hippocampal slices taken from 36 to 38 and from 70 to 80-week-old rats, when compared with ltp magnitude in slices from 4 or 10 to 15-week-old rats; this enhancement does not impact in cognitive improvement as aged rats revealed an impairment on hippocampal-dependent learning and memory performance, as assessed by the morris water maze tests. |
2012-05-08 |
2023-08-12 |
rat |
| Wei-Zu Li, Wei-Ping Li, Da-Ke Huang, Hong-Wei Kan, Xin Wang, Wang-Yang Wu, Yan-Yan Yin, Yu-You Ya. Dexamethasone and Aβ₂₅-₃₅ accelerate learning and memory impairments due to elevate amyloid precursor protein expression and neuronal apoptosis in 12-month male rats. Behavioural brain research. vol 227. issue 1. 2012-04-23. PMID:22061800. |
in this study, 12-month-old male rats were chronically treated with aβ(25-35) (10 μg/rat, hippocampal ca1 injection) and dexamethasone (dex, 1.5mg/kg) for 14 days to investigate the effects of dex and aβ(25-35) treatment on learning and memory impairments, pathological changes, neuronal ultrastructure, amyloid precursor protein (app) processing and neuronal cell apoptosis. |
2012-04-23 |
2023-08-12 |
rat |
| Amir S Bahar, Matthew L Shapir. Remembering to learn: independent place and journey coding mechanisms contribute to memory transfer. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 6. 2012-03-27. PMID:22323731. |
to investigate how these signals inform learning and memory for new and familiar episodes, we recorded ca1 and ca3 activity in rats trained to perform a "standard" spatial memory task in a plus maze and in two new task variants. |
2012-03-27 |
2023-08-12 |
rat |
| Wu-Fu Chen, Jong-Hau Hsu, Chien-Seng Lin, Yuh-Jyh Jong, Chun-Hwa Yang, Lih-Tung Huang, San-Nan Yan. Granulocyte-colony stimulating factor alleviates perinatal hypoxia-induced decreases in hippocampal synaptic efficacy and neurogenesis in the neonatal rat brain. Pediatric research. vol 70. issue 6. 2012-03-19. PMID:21857381. |
we investigated whether the damaged synaptic efficacy and neurogenesis within hippocampal ca1 region (an essential integration area for mammalian learning and memory) of the neonatal rat brain after perinatal hypoxia were restored by granulocyte-colony stimulating factor (g-csf) therapy. |
2012-03-19 |
2023-08-12 |
rat |
| A M Aleisa, G Helal, I A Alhaider, K H Alzoubi, M Srivareerat, T T Tran, S S Al-Rejaie, K A Alkadh. Acute nicotine treatment prevents REM sleep deprivation-induced learning and memory impairment in rat. Hippocampus. vol 21. issue 8. 2012-03-16. PMID:20865738. |
treatment of normal rats with nicotine for 24 or 48 h did not enhance spatial learning and memory or affect magnitude of ltp in the ca1 and dg regions. |
2012-03-16 |
2023-08-12 |
rat |
| Kebreten F Manaye, Joanne S Allard, Sara Kalifa, Amy C Drew, Guang Xu, Donald K Ingram, Rafael de Cabo, Peter R Mouto. 17α-estradiol attenuates neuron loss in ovariectomized Dtg AβPP/PS1 mice. Journal of Alzheimer's disease : JAD. vol 23. issue 4. 2012-03-06. PMID:21157032. |
here we report that by 13 months of age these dtg aβpp(swe)/ps1(Δe9) mice also show significant loss of pyramidal neuron in a critical region for learning and memory, the ca1 subregion of hippocampus, as a direct function of amyloid-β (aβ) aggregation. |
2012-03-06 |
2023-08-12 |
mouse |
| Sun Seek Min, Jihua An, Ji-Hye Lee, Geun Hee Seol, Jae Hyeung Im, Hye-Sun Kim, Tai-Kyoung Baik, Ran-Sook Wo. Neuregulin-1 prevents amyloid β-induced impairment of long-term potentiation in hippocampal slices via ErbB4. Neuroscience letters. vol 505. issue 1. 2012-02-28. PMID:21787838. |
the present study examined the effect of synthetic aβ₁₋₄₂ peptides on long-term potentiation (ltp) in the ca1 region of mice hippocampal slices, a cellular model of learning and memory. |
2012-02-28 |
2023-08-12 |
mouse |
| Qingsong Li, Shan Bian, Janet Hong, Yoko Kawase-Koga, Edwin Zhu, Yongri Zheng, Lizhuang Yang, Tao Su. Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. PloS one. vol 6. issue 10. 2012-02-06. PMID:21991391. |
the adult hippocampus consists of the dentate gyrus (dg) and the ca1, ca2 and ca3 regions and is essential for learning and memory functions. |
2012-02-06 |
2023-08-12 |
mouse |
| Leonie Welber. Learning and memory: CA1 triggers the trace. Nature reviews. Neuroscience. vol 12. issue 12. 2012-01-27. PMID:22068694. |
learning and memory: ca1 triggers the trace. |
2012-01-27 |
2023-08-12 |
Not clear |
| S Seo, P Liu, B Leitc. Spatial learning-induced accumulation of agmatine and glutamate at hippocampal CA1 synaptic terminals. Neuroscience. vol 192. 2012-01-18. PMID:21777660. |
these findings provide the first evidence that agmatine and glutamate are colocalized in synaptic terminals in the hippocampal ca1 region, and may co-participate in spatial learning and memory processing. |
2012-01-18 |
2023-08-12 |
rat |