| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xianwen Hu, Ye Zhang, Weiyan Li, Jian Liu, Yun L. Preconditioning with sevoflurane ameliorates spatial learning and memory deficit after focal cerebral ischemia-reperfusion in rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 31. issue 5. 2014-01-08. PMID:23628555. |
all results suggested that preconditioning with 2.4% sevoflurane could ameliorate the ability of spatial learning and memory after focal cerebral ischemia-reperfusion in rats via protecting the cholinergic neurons in hippocampal ca1 region. |
2014-01-08 |
2023-08-12 |
rat |
| Anis Talebi, Naser Naghdi, Hori Sepehri, Amaneh Rezayo. The Role of Estrogen Receptors on Spatial Learning and Memory in CA1 Region of Adult Male Rat Hippocampus. Iranian journal of pharmaceutical research : IJPR. vol 9. issue 2. 2013-12-23. PMID:24363726. |
the role of estrogen receptors on spatial learning and memory in ca1 region of adult male rat hippocampus. |
2013-12-23 |
2023-08-12 |
rat |
| Yukitoshi Izumi, Kazuko A O'Dell, Charles F Zorumsk. Metaplastic LTP inhibition after LTD induction in CA1 hippocampal slices involves NMDA Receptor-mediated Neurosteroidogenesis. Physiological reports. vol 1. issue 5. 2013-12-04. PMID:24303196. |
long-term depression (ltd) induced by low-frequency electrical stimulation (lfs) in the ca1 region of the hippocampus is a form of synaptic plasticity thought to contribute to learning and memory and to the pathophysiology of neuropsychiatric disorders. |
2013-12-04 |
2023-08-12 |
rat |
| Soheila Babanejad, Nasser Naghdi, Seyyed Ali Haeri Rohan. Microinjection of Dihydrotestosterone as a 5α-Reduced Metabolite of Testosterone into CA1 Region of Hippocampus Could Improve Spatial Learning in the Adult Male Rats. Iranian journal of pharmaceutical research : IJPR. vol 11. issue 2. 2013-11-19. PMID:24250491. |
ca1 region of hippocampus has an important role in learning and memory. |
2013-11-19 |
2023-08-12 |
rat |
| Soheila Babanejad, Nasser Naghdi, Seyyed Ali Haeri Rohan. Microinjection of Dihydrotestosterone as a 5α-Reduced Metabolite of Testosterone into CA1 Region of Hippocampus Could Improve Spatial Learning in the Adult Male Rats. Iranian journal of pharmaceutical research : IJPR. vol 11. issue 2. 2013-11-19. PMID:24250491. |
therefore, it is suggested that neurohormones in ca1 have an important role in learning and memory. |
2013-11-19 |
2023-08-12 |
rat |
| Somayeh Assadiannarenji, Nasser Naghdi, Shahrbanoo Oryan, Kayhan Azadmanes. Intrahippocampal Injection of 3α Diol (a Testosterone Metabolite ) and Indomethacin (3α-HSD Blocker), Impair Acquisition of Spatial Learning and Memory in Adult Male Rats. Iranian journal of pharmaceutical research : IJPR. vol 12. issue 3. 2013-11-19. PMID:24250652. |
it is concluded that intra ca1 administration of 3α diol and indomethacin could impair spatial learning and memory in acquisition stage. |
2013-11-19 |
2023-08-12 |
rat |
| Mahnaz Taherianfard, Maryam Sharifi, Mina Tadjali, Mahboubeh Kohkiloezade. Modulation of NR1 subunit of N-methyl-D-aspartate receptor by ovariectomy and passive avoidance learning. Iranian journal of neurology. vol 11. issue 4. 2013-11-19. PMID:24250883. |
two sites of mammalian brain which are important in learning and memory are ca1 region of hippocampus and purkinje cell layer of cerebellum. |
2013-11-19 |
2023-08-12 |
human |
| Anahita Torkaman-Boutorabi, Sara Soltani, Shahrbanoo Oryan, Mohaddeseh Ebrahimi-Ghiri, Mohammad Torabi-Nami, Mohammad-Reza Zarrindas. Involvement of the dorsal hippocampal GABA-A receptors in histamine-induced facilitation of memory in the Morris water maze. Pharmacology, biochemistry, and behavior. vol 105. 2013-10-23. PMID:23438692. |
previous investigations have shown that different receptor systems in the ca1 region of hippocampus are involved in learning and memory functions. |
2013-10-23 |
2023-08-12 |
rat |
| Yi Wang, Wei Wei, Yuan Wang, Jing Dong, Binbin Song, Hui Min, Weiping Teng, Jie Che. Neurotoxicity of developmental hypothyroxinemia and hypothyroidism in rats: Impairments of long-term potentiation are mediated by phosphatidylinositol 3-kinase signaling pathway. Toxicology and applied pharmacology. vol 271. issue 2. 2013-10-21. PMID:23707767. |
thus, in the present study, we investigated the effects of developmental hypothyroxinemia and hypothyroidism on long-term potentiation (ltp), a widely accepted cellular model of learning and memory, in the hippocampal ca1 region. |
2013-10-21 |
2023-08-12 |
rat |
| Heather D VanGuilder Starkey, Georgina V Bixler, William E Sonntag, Willard M Freema. Expression of NgR1-antagonizing proteins decreases with aging and cognitive decline in rat hippocampus. Cellular and molecular neurobiology. vol 33. issue 4. 2013-10-17. PMID:23525710. |
to determine whether these endogenous ngr1-inhibiting proteins may play a compensatory role in age-related cognitive impairment by counteracting overexpression of ngr1 agonists and co-receptors, we quantified the expression of lotus, lgi1, and adam22 in hippocampal ca1, ca3 and dg subregions dissected from mature adult and aged rats cognitively phenotyped for spatial learning and memory by morris water maze testing. |
2013-10-17 |
2023-08-12 |
rat |
| Xue-Jun Zhang, Qiang W. [Effects of electroacupuncture at different acupoints on learning and memory ability and PSD-95 protein expression on hippocampus CA1 in rats with autism]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 33. issue 7. 2013-10-17. PMID:24032199. |
[effects of electroacupuncture at different acupoints on learning and memory ability and psd-95 protein expression on hippocampus ca1 in rats with autism]. |
2013-10-17 |
2023-08-12 |
rat |
| Kim Nuytens, Ilse Gantois, Pieter Stijnen, Emilia Iscru, Annelies Laeremans, Lutgarde Serneels, Lien Van Eylen, Stephen A Liebhaber, Koen Devriendt, Detlef Balschun, Lutgarde Arckens, John W M Creemers, Rudi D'Hoog. Haploinsufficiency of the autism candidate gene Neurobeachin induces autism-like behaviors and affects cellular and molecular processes of synaptic plasticity in mice. Neurobiology of disease. vol 51. 2013-07-24. PMID:23153818. |
nbea(+/-) mice exhibit several asd-like features, including changes in self-grooming behavior, social behaviors, conditioned fear responses, and spatial learning and memory, which coincided with enhanced long-term potentiation (ltp) in their ca1 region. |
2013-07-24 |
2023-08-12 |
mouse |
| Kim Nuytens, Ilse Gantois, Pieter Stijnen, Emilia Iscru, Annelies Laeremans, Lutgarde Serneels, Lien Van Eylen, Stephen A Liebhaber, Koen Devriendt, Detlef Balschun, Lutgarde Arckens, John W M Creemers, Rudi D'Hoog. Haploinsufficiency of the autism candidate gene Neurobeachin induces autism-like behaviors and affects cellular and molecular processes of synaptic plasticity in mice. Neurobiology of disease. vol 51. 2013-07-24. PMID:23153818. |
the observed alterations in learning and memory and hippocampal ltp are concomitant with decreased expression of the immediate early gene zif268 in dorsomedial striatum and hippocampal ca1 region, increased creb phosphorylation, and increased hippocampal bdnf expression. |
2013-07-24 |
2023-08-12 |
mouse |
| Rameshwar Singh, Monika Mishra, Sangeeta Singh, Deepak Sharm. Effect of L-deprenyl treatment on electrical activity, Na+, K+ ATPase, and protein kinase C activities in hippocampal subfields (CA1 and CA3) of aged rat brain. Indian journal of experimental biology. vol 50. issue 2. 2013-06-10. PMID:22670472. |
the ca1 and ca3 hippocampal areas are the sites at which initial learning and memory processes occur. |
2013-06-10 |
2023-08-12 |
rat |
| Hamid Kalalian-Moghaddam, Tourandokht Baluchnejadmojarad, Mehrdad Roghani, Fatemeh Goshadrou, Abdolaziz Ronagh. Hippocampal synaptic plasticity restoration and anti-apoptotic effect underlie berberine improvement of learning and memory in streptozotocin-diabetic rats. European journal of pharmacology. vol 698. issue 1-3. 2013-06-10. PMID:23099256. |
this study was conducted to evaluate the effect of berberine on hippocampal ca1 neuronal apoptosis, synaptic plasticity and learning and memory of streptozotocin (stz)-diabetic rats. |
2013-06-10 |
2023-08-12 |
rat |
| Hamid Kalalian-Moghaddam, Tourandokht Baluchnejadmojarad, Mehrdad Roghani, Fatemeh Goshadrou, Abdolaziz Ronagh. Hippocampal synaptic plasticity restoration and anti-apoptotic effect underlie berberine improvement of learning and memory in streptozotocin-diabetic rats. European journal of pharmacology. vol 698. issue 1-3. 2013-06-10. PMID:23099256. |
restored ps amplitude and fepsp and ameliorated learning and memory impairment and attenuated apoptosis of pyramidal neurons in the ca1 area, as determined by the terminal deoxynucleotidyl transferase (tdt)-mediated dutp nick end-labeling method. |
2013-06-10 |
2023-08-12 |
rat |
| Wei-Na Han, Christian Hölscher, Li Yuan, Wei Yang, Xiao-Hui Wang, Mei-Na Wu, Jin-Shun Q. Liraglutide protects against amyloid-β protein-induced impairment of spatial learning and memory in rats. Neurobiology of aging. vol 34. issue 2. 2013-04-29. PMID:22592020. |
we found that (1) bilateral intrahippocampal injection of aβ(25-35) resulted in a significant decline of spatial learning and memory of rats in water maze tests, together with a serious depression of in vivo hippocampal late-phase long-term potentiation (l-ltp) in ca1 region of rats; (2) pretreatment with liraglutide effectively and dose-dependently protected against the aβ(25-35)-induced impairment of spatial memory and deficit of l-ltp; (3) liraglutide injection also activated camp signal pathway in the brain, with a nearly doubled increase in the camp contents compared with control. |
2013-04-29 |
2023-08-12 |
rat |
| Rui-Feng Liang, Wei-Qing Li, Xiao-Hui Wang, Hui-Fang Zhang, Hong Wang, Jun-Xia Wang, Yu Zhang, Ming-Tao Wan, Bao-Long Pan, Qiao Ni. Aluminium-maltolate-induced impairment of learning, memory and hippocampal long-term potentiation in rats. Industrial health. vol 50. issue 5. 2013-04-05. PMID:22878356. |
our studies indicate that subchronic al (mal)(3) exposure significantly impaired spatial learning and memory abilities, suppressed the ltp in the ca1 hippocampal area, and elevated al levels in cerebral cortex in a dose-dependent fashion. |
2013-04-05 |
2023-08-12 |
rat |
| Hiroki Fujiwara, Kotaro Ikarashi, Yoshihiko Yamazaki, Jun-Ichi Goto, Kenya Kaneko, Makoto Sugita, Hiroshi Kato, Hiroshi Sasaki, Jin-Ichi Inokuchi, Koichi Furukawa, Satoshi Fuji. Impairment of hippocampal long-term potentiation and failure of learning in mice treated with d-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol. Biomedical research (Tokyo, Japan). vol 33. issue 5. 2013-03-25. PMID:23124246. |
these results indicate that de novo synthesis of gangliosides in the brain is involved in synaptic plasticity of ltp in mouse hippocampal ca1 neurons and plays important roles in learning and memory. |
2013-03-25 |
2023-08-12 |
mouse |
| Na Liu, Hua Xing, Shan-Xiang Jian. [Involvement of stress-induced hippocampal synaptic potentiation in the novelty acquisition]. Sheng li xue bao : [Acta physiologica Sinica]. vol 63. issue 2. 2013-01-31. PMID:21505728. |
to study the influence of behavioral stress on hippocampal spatial learning and memory, we used the freely moving rats that had undergone chronic implantation of a recording electrode in the hippocampus ca1 region and a bipolar stimulating electrode in the ipsilateral schaffer collateral-commissural pathway. |
2013-01-31 |
2023-08-12 |
rat |