| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takahiro Yaguchi, Tetsu Nagata, Tomoyuki Nishizak. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine improves cognitive decline by enhancing long-term depression. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19482045. |
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (pophtcho) (1 microm) enhanced long-term depression (ltd), a synaptic plasticity relevant to learning and memory, in the ca1 region of rat hippocampal slices, where expression of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (ampa) receptor subunit glur1 on the plasma membrane was decreased. |
2009-12-01 |
2023-08-12 |
rat |
| Evelin L Schaeffer, Barbara A Novaes, Emanuelle R da Silva, Heni D Skaf, Alvaro G Mendes-Net. Strategies to promote differentiation of newborn neurons into mature functional cells in Alzheimer brain. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 7. 2009-11-17. PMID:19596396. |
alzheimer disease (ad) is characterized by neuron loss in the hippocampus (dg and ca1 field), entorhinal cortex, and association neocortex, which underlies the learning and memory deficits. |
2009-11-17 |
2023-08-12 |
Not clear |
| Margarita Ivanova, Alexandar Ternianov, Roman Tashev, Stiliana Belcheva, Iren Belchev. Lateralized learning and memory effects of vasoactive intestinal peptide infused into the rat hippocampal CA1 area. Regulatory peptides. vol 156. issue 1-3. 2009-09-18. PMID:19465061. |
lateralized learning and memory effects of vasoactive intestinal peptide infused into the rat hippocampal ca1 area. |
2009-09-18 |
2023-08-12 |
rat |
| Margarita Ivanova, Alexandar Ternianov, Roman Tashev, Stiliana Belcheva, Iren Belchev. Lateralized learning and memory effects of vasoactive intestinal peptide infused into the rat hippocampal CA1 area. Regulatory peptides. vol 156. issue 1-3. 2009-09-18. PMID:19465061. |
the effects of vip microinjected unilaterally (left or right) and bilaterally (left and right) at a dose of 50 ng into hippocampal ca1 area of male wistar rats on learning and memory (shuttle-box) were studied. |
2009-09-18 |
2023-08-12 |
rat |
| Wei-wei Ma, Li Xiang, Huan-Ling Yu, Lin-Hong Yuan, Ai-Min Guo, Yi-Xiu Xiao, Li Li, Rong Xia. Neuroprotection of soyabean isoflavone co-administration with folic acid against beta-amyloid 1-40-induced neurotoxicity in rats. The British journal of nutrition. vol 102. issue 4. 2009-09-11. PMID:19534845. |
in the present study, the learning and memory ability of rats and the amount of amyloid-positive neurons in the cerebral cortex and hippocampal ca1 area were measured. |
2009-09-11 |
2023-08-12 |
rat |
| X Guan, R Zhang, Y Xu, S L. Cocaine withdrawal enhances long-term potentiation in rat hippocampus via changing the activity of corticotropin-releasing factor receptor subtype 2. Neuroscience. vol 161. issue 3. 2009-08-24. PMID:19376201. |
in the present study, the effects of chronic cocaine treatment (a 14-day cocaine administration, 20 mg/kg i.p., daily) and short-term cocaine withdrawal (a 3-day cocaine extinction following a 14-day cocaine administration) on long-term potentiation (ltp), one prominent cellular mechanism for learning and memory, were assessed in the ca1 region of the rat hippocampal slices. |
2009-08-24 |
2023-08-12 |
rat |
| Yan Zhou, Hui Song, Zong Ning, Lei Tian, Lin Xu, Ning M. [Effects of Panax notoginseng saponins on long-term potentiation in the CA1 region of the rat hippocampus]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 42. issue 11. 2009-08-06. PMID:18300467. |
in this study, we used blind whole-cell voltage-clamp recordings to detect the effects of pns on long-term potentiation (ltp) in the ca1 region of the hippocampus, and investigated the electrophysiological mechanisms underlying potentiating effects of pns on learning and memory. |
2009-08-06 |
2023-08-12 |
rat |
| Yan Zhou, Hui Song, Zong Ning, Lei Tian, Lin Xu, Ning M. [Effects of Panax notoginseng saponins on long-term potentiation in the CA1 region of the rat hippocampus]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 42. issue 11. 2009-08-06. PMID:18300467. |
in conclusion, 0.04 - 0.05 g x l(-1) pns could facilitate ltp in the ca1 region of the rat hippocampus and it is reasonable to suggest that this action may contribute to its potentiating effects on learning and memory. |
2009-08-06 |
2023-08-12 |
rat |
| Omar Bennani, Gilbert Chauvet, Pierre Chauvet, Jean-Marc Dupont, Francois Joue. A hierarchical modeling approach of hippocampus local circuit. Journal of integrative neuroscience. vol 8. issue 1. 2009-07-29. PMID:19412980. |
the specific case of the hippocampus is presented, as well as how a drug allows learning and memory improvement in the local circuit of the ca1 area of the hippocampus. |
2009-07-29 |
2023-08-12 |
Not clear |
| A Oh-Nishi, M Saji, S-Z Satoh, M Ogata, N Suzuk. Late phase of long-term potentiation induced by co-application of N-methyl-d-aspartic acid and the antagonist of NR2B-containing N-methyl-d-aspartic acid receptors in rat hippocampus. Neuroscience. vol 159. issue 1. 2009-06-25. PMID:19010396. |
activation of n-methyl-d-aspartic acid (nmda) glutamate receptors (nmdars) is required for long-term potentiation (ltp) of excitatory synaptic transmission at hippocampal ca1 synapses, the proposed cellular mechanisms of learning and memory. |
2009-06-25 |
2023-08-12 |
rat |
| C S Lin, P L Tao, Y J Jong, W F Chen, C H Yang, L T Huang, C F Chao, S N Yan. Prenatal morphine alters the synaptic complex of postsynaptic density 95 with N-methyl-D-aspartate receptor subunit in hippocampal CA1 subregion of rat offspring leading to long-term cognitive deficits. Neuroscience. vol 158. issue 4. 2009-05-20. PMID:19041927. |
in this study, we determined whether prenatal morphine exposure altered the synaptic complex association between psd-95 and three major nmdar subunits (nr1, nr2a, and nr2b), at the mrna and protein levels, within the hippocampal ca1 subregion (an important integration area for mammalian learning and memory) of rat offspring along with the performance of long-term cognitive functions. |
2009-05-20 |
2023-08-12 |
rat |
| Liang Cai Gao, Yu Ting Wang, Xun Lao, Cong Wang, Feng Yi Wang, Chong Gang Yua. [The change of learning and memory ability in the rat model of depression]. Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology. vol 42. issue 1. 2009-04-21. PMID:19306685. |
the method of morris water maze was used to measure learning and memory ability and the results of ltp and ltd in hippocampus ca1 were recorded to observe the synaptic plasticity of hippocampus neurons. |
2009-04-21 |
2023-08-12 |
rat |
| Farzaneh Ghiafeh Davoodi, Fereshteh Motamedi, Nasser Naghdi, Esmaeil Akbar. Effect of reversible inactivation of the reuniens nucleus on spatial learning and memory in rats using Morris water maze task. Behavioural brain research. vol 198. issue 1. 2009-03-30. PMID:19038291. |
re is major source of thalamic afferents to the hippocampus and has been shown to exert powerful excitatory action on ca1 of hippocampus, which is supposed to be involved in learning and memory processes. |
2009-03-30 |
2023-08-12 |
rat |
| Karem H Alzoubi, Nashaat Z Gerges, Abdulaziz M Aleisa, Karim A Alkadh. Levothyroxin restores hypothyroidism-induced impairment of hippocampus-dependent learning and memory: Behavioral, electrophysiological, and molecular studies. Hippocampus. vol 19. issue 1. 2009-02-27. PMID:18680156. |
immunoblot analysis of signaling molecules, including cyclic-amp response element binding protein (creb), mitogen-activated protein kinases (mapkp44/42; erk1/2), in area ca1 revealed that thyroxin treatment reversed hypothyroidism-induced reduction of signaling molecules essential for learning and memory, and l-ltp. |
2009-02-27 |
2023-08-12 |
rat |
| Feng Gu, Jianting Shi, Ying Wen, Hui Fan, Jinfeng Hu, Yinghe Hu, Zheng Zha. Translational responses of NR2B overexpression in the cerebral cortex of transgenic mice: a liquid chromatography-based proteomic approach. Brain research. vol 1250. 2009-02-27. PMID:19007751. |
the nr2b transgenic mice exhibited larger ltp in the hippocampal ca1 region and enhanced behavioral performance in several learning and memory tasks. |
2009-02-27 |
2023-08-12 |
mouse |
| Anastasia P Arvanitidis, Dale Corbett, Frederick Colbourn. A high fat diet does not exacerbate CA1 injury and cognitive deficits following global ischemia in rats. Brain research. vol 1252. 2009-02-27. PMID:19071094. |
second, we evaluated the influence of a 60-day wd regimen on hippocampal ca1 injury and learning and memory impairments following global ischemia in rats (experiment 2). |
2009-02-27 |
2023-08-12 |
rat |
| Anastasia P Arvanitidis, Dale Corbett, Frederick Colbourn. A high fat diet does not exacerbate CA1 injury and cognitive deficits following global ischemia in rats. Brain research. vol 1252. 2009-02-27. PMID:19071094. |
eight minutes of ischemia in experiment 2 induced severe hippocampal ca1 cell loss (approximately 90%) and learning and memory impairments relative to non-ischemic controls. |
2009-02-27 |
2023-08-12 |
rat |
| Michael Stramiello, John J Wagne. D1/5 receptor-mediated enhancement of LTP requires PKA, Src family kinases, and NR2B-containing NMDARs. Neuropharmacology. vol 55. issue 5. 2009-01-15. PMID:18644393. |
the results identify a crucial role for nr2b-containing nmda receptors in the modulation of ltp by d1/5-receptors in the ca1, suggesting that endogenously released dopamine may act through this mechanism as a modulator of hippocampal-dependent learning and memory tasks. |
2009-01-15 |
2023-08-12 |
rat |
| Gregory M Dillon, Xianlu Qu, Jacob N Marcus, Jean-Cosme Dodar. Excitotoxic lesions restricted to the dorsal CA1 field of the hippocampus impair spatial memory and extinction learning in C57BL/6 mice. Neurobiology of learning and memory. vol 90. issue 2. 2008-11-18. PMID:18602845. |
in the present study, we investigated the effects of excitotoxic (nmda) lesions of dorsal ca1 on several aspects of learning and memory performance in mice. |
2008-11-18 |
2023-08-12 |
mouse |
| Gregory M Dillon, Xianlu Qu, Jacob N Marcus, Jean-Cosme Dodar. Excitotoxic lesions restricted to the dorsal CA1 field of the hippocampus impair spatial memory and extinction learning in C57BL/6 mice. Neurobiology of learning and memory. vol 90. issue 2. 2008-11-18. PMID:18602845. |
taken together, our results indicate that lesions to dorsal ca1 in mice induce selective learning and memory performance deficits similar to those observed in other species, and extend previous findings indicating that this region of the hippocampus is critically involved in the processing of spatial information and/or the processing of inhibitory responses. |
2008-11-18 |
2023-08-12 |
mouse |