| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| San-Nan Yang, Chung-Bin Huang, Chin-Hwa Yang, Ming-Chi Lai, Wu-Fu Chen, Chih-Lu Wang, Chia-Lu Wu, Li-Tung Huan. Impaired SynGAP expression and long-term spatial learning and memory in hippocampal CA1 area from rats previously exposed to perinatal hypoxia-induced insults: beneficial effects of A68930. Neuroscience letters. vol 371. issue 1. 2005-01-03. PMID:15500970. |
impaired syngap expression and long-term spatial learning and memory in hippocampal ca1 area from rats previously exposed to perinatal hypoxia-induced insults: beneficial effects of a68930. |
2005-01-03 |
2023-08-12 |
rat |
| San-Nan Yang, Chung-Bin Huang, Chin-Hwa Yang, Ming-Chi Lai, Wu-Fu Chen, Chih-Lu Wang, Chia-Lu Wu, Li-Tung Huan. Impaired SynGAP expression and long-term spatial learning and memory in hippocampal CA1 area from rats previously exposed to perinatal hypoxia-induced insults: beneficial effects of A68930. Neuroscience letters. vol 371. issue 1. 2005-01-03. PMID:15500970. |
in the hippocampal ca1 region, perinatal hypoxia insults (p10) led to a reduction in syngap expression associated with impairment in long-term spatial learning and memory performance at p45. |
2005-01-03 |
2023-08-12 |
rat |
| Gretchen N Neigh, Erica R Glasper, Julia Kofler, Richard J Traystman, Ronald F Mervis, Adam Bachstetter, A Courtney DeVrie. Cardiac arrest with cardiopulmonary resuscitation reduces dendritic spine density in CA1 pyramidal cells and selectively alters acquisition of spatial memory. The European journal of neuroscience. vol 20. issue 7. 2004-12-22. PMID:15380008. |
the current study used the morris water maze to characterize spatial learning and memory deficits elicited by 8 min of cardiac arrest with cardiopulmonary resuscitation (ca/cpr) in mice, which is associated with a 25-50% decrease in ca1 neurons. |
2004-12-22 |
2023-08-12 |
mouse |
| Lei Shi, Anne Elizabeth Argenta, Adam Kerrissey Winseck, Judy Karen Brunso-Bechtol. Stereological quantification of GAD-67-immunoreactive neurons and boutons in the hippocampus of middle-aged and old Fischer 344 x Brown Norway rats. The Journal of comparative neurology. vol 478. issue 3. 2004-12-02. PMID:15368530. |
it is possible that loss of ca1 inhibitory interneurons in the dorsal hippocampus contributes to the learning and memory impairments reported in old rats. |
2004-12-02 |
2023-08-12 |
rat |
| Alessandra Ottani, Anna Valeria Vergoni, Sabrina Saltini, Chiara Mioni, Daniela Giuliani, Marta Bartiromo, Davide Zaffe, Annibale R Botticelli, Anna Ferrari, Alfio Bertolini, Susanna Genedan. Effect of late treatment with gamma-hydroxybutyrate on the histological and behavioral consequences of transient brain ischemia in the rat. European journal of pharmacology. vol 485. issue 1-3. 2004-10-05. PMID:14757139. |
in saline-treated animals, 30 min of global ischemia followed by reperfusion caused a massive loss of neurons in the hippocampal ca1 subfield (examined 63 days after the ischemic episode), and an impairment of sensory-motor performance (tested on the 51st and 63rd days after ischemia) and of spatial learning and memory (evaluated starting 46 days after the ischemic episode). |
2004-10-05 |
2023-08-12 |
rat |
| Lidong Liu, Tak Pan Wong, Mario F Pozza, Kurt Lingenhoehl, Yushan Wang, Morgan Sheng, Yves P Auberson, Yu Tian Wan. Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science (New York, N.Y.). vol 304. issue 5673. 2004-05-21. PMID:15143284. |
activation of n-methyl-d-aspartate subtype glutamate receptors (nmdars) is required for long-term potentiation (ltp) and long-term depression (ltd) of excitatory synaptic transmission at hippocampal ca1 synapses, the proposed cellular substrates of learning and memory. |
2004-05-21 |
2023-08-12 |
Not clear |
| Janet M Choi, Russell D Romeo, Wayne G Brake, Cynthia L Bethea, Zev Rosenwaks, Bruce S McEwe. Estradiol increases pre- and post-synaptic proteins in the CA1 region of the hippocampus in female rhesus macaques (Macaca mulatta). Endocrinology. vol 144. issue 11. 2003-12-03. PMID:12960039. |
in female rats, e increases dendritic spine number, synaptogenesis, and synaptic proteins in the ca1 region of the hippocampus, an area of the brain that mediates learning and memory. |
2003-12-03 |
2023-08-12 |
rat |
| R Bartesaghi, S Severi, S Guid. Effects of early environment on pyramidal neuron morphology in field CA1 of the guinea-pig. Neuroscience. vol 116. issue 3. 2003-05-07. PMID:12573714. |
the neuroanatomical changes caused by isolation in field ca1 and in the two other elements of the trisynaptic circuit are likely to be associated with changes in the physiology of the hippocampal formation and in cognitive processes such as learning and memory in which the hippocampal formation plays a pivotal role. |
2003-05-07 |
2023-08-12 |
Not clear |
| Nasser Naghdi, Nahid Majlessi, Tahereh Bozorgmeh. The effects of anisomycin (a protein synthesis inhibitor) on spatial learning and memory in CA1 region of rats hippocampus. Behavioural brain research. vol 139. issue 1-2. 2003-05-02. PMID:12642177. |
the effects of anisomycin (a protein synthesis inhibitor) on spatial learning and memory in ca1 region of rats hippocampus. |
2003-05-02 |
2023-08-12 |
rat |
| Huangui Xiong, Jeffery Boyle, Matthew Winkelbauer, Santhi Gorantla, Jialin Zheng, Anuja Ghorpade, Yuri Persidsky, Kimberly A Carlson, Howard E Gendelma. Inhibition of long-term potentiation by interleukin-8: implications for human immunodeficiency virus-1-associated dementia. Journal of neuroscience research. vol 71. issue 4. 2003-04-01. PMID:12548717. |
to determine the role that il-8 might play in the neuronal dysfunction in had, we studied its effect on synaptic transmission and plasticity in the ca1 region of hippocampus, the seat of learning and memory. |
2003-04-01 |
2023-08-12 |
human |
| Yin Feng, Lie-Xiong Zhang, Dong-Man Cha. [Role of melatonin in spatial learning and memory in rats and its mechanism]. Sheng li xue bao : [Acta physiologica Sinica]. vol 54. issue 1. 2003-02-03. PMID:11930244. |
our results showed that application of melatonin in rats significantly inhibited not only spatial learning and memory, but also ltp in ca1 area. |
2003-02-03 |
2023-08-12 |
rat |
| Cord Brakebusch, Constanze I Seidenbecher, Fredrik Asztely, Uwe Rauch, Henry Matthies, Hannelore Meyer, Manfred Krug, Tobias M Böckers, Xiaohong Zhou, Michael R Kreutz, Dirk Montag, Eckart D Gundelfinger, Reinhard Fässle. Brevican-deficient mice display impaired hippocampal CA1 long-term potentiation but show no obvious deficits in learning and memory. Molecular and cellular biology. vol 22. issue 21. 2002-11-22. PMID:12370289. |
brevican-deficient mice display impaired hippocampal ca1 long-term potentiation but show no obvious deficits in learning and memory. |
2002-11-22 |
2023-08-12 |
mouse |
| Yoshihiko Yamazaki, Naoya Hamaue, Katumi Sumikaw. Nicotine compensates for the loss of cholinergic function to enhance long-term potentiation induction. Brain research. vol 946. issue 1. 2002-10-28. PMID:12133604. |
long-term potentiation (ltp) in the hippocampal ca1 region is widely regarded to be the cellular substrate of learning and memory, and its induction critically depends on the activation of n-methyl-d-aspartate receptors (nmdars). |
2002-10-28 |
2023-08-12 |
Not clear |
| K H Braunewell, D Manahan-Vaugha. Long-term depression: a cellular basis for learning? Reviews in the neurosciences. vol 12. issue 2. 2001-10-25. PMID:11392454. |
this review focuses on the interpretation of novel and established information with regard to ltd in the hippocampal ca1 region in terms of its possible role as a cellular basis for learning and memory. |
2001-10-25 |
2023-08-12 |
human |
| Z Galdzicki, R Siarey, R Pearce, J Stoll, S I Rapopor. On the cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models. Brain research. Brain research reviews. vol 35. issue 2. 2001-07-26. PMID:11336779. |
another animal model, the adult segmental trisomy 16 mouse (ts65dn), demonstrates reduced long-term potentiation and increased long-term depression (models for learning and memory related to synaptic plasticity) in the ca1 region of the hippocampus. |
2001-07-26 |
2023-08-12 |
mouse |
| S Fujii, K Sumikaw. Nicotine accelerates reversal of long-term potentiation and enhances long-term depression in the rat hippocampal CA1 region. Brain research. vol 894. issue 2. 2001-06-07. PMID:11251213. |
in the hippocampal ca1 region, low-frequency stimulation (lfs; 200 pulses at 1 hz) causes reversal of long-term potentiation (depotentiation, dp) and long-term depression (ltd), both of which are thought to be the cellular substrate of learning and memory. |
2001-06-07 |
2023-08-12 |
rat |
| S Fujii, K Sumikaw. Nicotine accelerates reversal of long-term potentiation and enhances long-term depression in the rat hippocampal CA1 region. Brain research. vol 894. issue 2. 2001-06-07. PMID:11251213. |
because nicotine enhances learning and memory, we examined if nicotine modulates dp and ltd in the hippocampal ca1 region. |
2001-06-07 |
2023-08-12 |
rat |
| T L Briones, B Therrie. Behavioral effects of transient cerebral ischemia. Biological research for nursing. vol 1. issue 4. 2001-03-22. PMID:11232206. |
ca1 neurons in the hippocampus, a brain structure involved in learning and memory, are selectively vulnerable to ischemic effects. |
2001-03-22 |
2023-08-12 |
rat |
| S Laroche, S Davis, T M Ja. Plasticity at hippocampal to prefrontal cortex synapses: dual roles in working memory and consolidation. Hippocampus. vol 10. issue 4. 2000-12-22. PMID:10985283. |
the existence of a direct monosynaptic pathway from the ventral ca1 region of the hippocampus and subiculum to specific areas of the prefrontal cortex provides a useful model for conceptualizing the functional operations of hippocampal-prefrontal cortex communication in learning and memory. |
2000-12-22 |
2023-08-12 |
Not clear |
| S Li, R Anwyl, M J Rowa. A persistent reduction in short-term facilitation accompanies long-term potentiation in the CA1 area in the intact hippocampus. Neuroscience. vol 100. issue 2. 2000-11-28. PMID:11008161. |
this suggests that there is considerable variation in the fidelity of temporal information storage at different synapses during learning and memory in the ca1 area. |
2000-11-28 |
2023-08-12 |
rat |