Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
E Miyamoto, K Fukunag. A role of Ca2+/calmodulin-dependent protein kinase II in the induction of long-term potentiation in hippocampal CA1 area. Neuroscience research. vol 24. issue 2. 1997-03-19. PMID:8929917. |
long-term potentiation (ltp) in the ca1 area of the hippocampus is considered to be a synaptic model for learning and memory. |
1997-03-19 |
2023-08-12 |
Not clear |
J J Kim, M R Foy, R F Thompso. Behavioral stress modifies hippocampal plasticity through N-methyl-D-aspartate receptor activation. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 10. 1996-07-18. PMID:8643474. |
we now report that in adult male rats, stress (i.e., restraint plus tailshock) impairs long-term potentiation (ltp) but enhances long-term depression (ltd) in the ca1 area of the hippocampus, a structure implicated in learning and memory processes. |
1996-07-18 |
2023-08-12 |
rat |
M Amano, M Hasegawa, T Hasegawa, T Nabeshim. Characteristics of transient cerebral ischemia-induced deficits on various learning and memory tasks in male Mongolian gerbils. Japanese journal of pharmacology. vol 63. issue 4. 1994-04-05. PMID:8121080. |
these findings suggest that the impairment of performance in the hab and pa within 2 days after occlusion may be related to an early phase of ca1 neuronal death and to hyperlocomotion, although the impairment of spatial learning and memory was clearly associated with ca1 injury 10 days after ischemia. |
1994-04-05 |
2023-08-12 |
Not clear |
V Tancredi, G D'Arcangelo, D Mercanti, P Calissan. Nerve growth factor inhibits the expression of long-term potentiation in hippocampal slices. Neuroreport. vol 4. issue 2. 1993-04-22. PMID:8384022. |
nerve growth factor and its receptor(s) are present in several parts of the hippocampus (ca1, ca3, dentate gyrus) but nothing is known about their function in this area which plays a fundamental role in learning and memory processes. |
1993-04-22 |
2023-08-12 |
Not clear |
L A Mudrick, K G Baimbridg. Hippocampal neurons transplanted into ischemically lesioned hippocampus: anatomical assessment of survival, maturation and integration. Experimental brain research. vol 86. issue 2. 1992-02-03. PMID:1721874. |
the ca1 region of the hippocampal formation is the region of the brain that is most often lesioned following transient forebrain ischemia and is associated with impairments of learning and memory. |
1992-02-03 |
2023-08-11 |
rat |
I Shinoda, Y Furukawa, S Furukaw. Stimulation of nerve growth factor synthesis/secretion by propentofylline in cultured mouse astroglial cells. Biochemical pharmacology. vol 39. issue 11. 1990-06-28. PMID:2344376. |
the xanthine derivative propentofylline has been reported to exhibit protective effects on neuronal cells in the brain, which include improvement of impaired learning and memory and protection against delayed ischemically-induced neuronal cell death in the hippocampal ca1 subfield. |
1990-06-28 |
2023-08-11 |
mouse |
B C Rogers, M I Barnes, C L Mitchell, H A Tilso. Functional deficits after sustained stimulation of the perforant path. Brain research. vol 493. issue 1. 1989-10-25. PMID:2776009. |
the learning and memory deficits were associated with a loss of ca1 and ca3 pyramidal cells and pretreatment with the n-methyl-d-aspartate antagonist mk-801 reduced this cell loss, particularly in the ca1 region of the hippocampus. |
1989-10-25 |
2023-08-11 |
Not clear |