| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Justin T Rogers, Ian Rusiana, Justin Trotter, Lisa Zhao, Erika Donaldson, Daniel T S Pak, Lenard W Babus, Melinda Peters, Jessica L Banko, Pascale Chavis, G William Rebeck, Hyang-Sook Hoe, Edwin J Weebe. Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density. Learning & memory (Cold Spring Harbor, N.Y.). vol 18. issue 9. 2011-12-15. PMID:21852430. |
these changes correlated with increased dendritic spine density, increased hippocampal ca1 long-term potentiation (ltp), and enhanced performance in associative and spatial learning and memory. |
2011-12-15 |
2023-08-12 |
mouse |
| Amir S Bahar, Prasad R Shirvalkar, Matthew L Shapir. Memory-guided learning: CA1 and CA3 neuronal ensembles differentially encode the commonalities and differences between situations. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 34. 2011-11-07. PMID:21865470. |
ca1 and ca3 place fields thus revealed different coding dynamics that correlated with both learning and memory performance. |
2011-11-07 |
2023-08-12 |
rat |
| Wei-Zu Li, Wei-Ping Li, Wen Zhang, Yan-Yan Yin, Xiang-Xiang Sun, Su-Su Zhou, Xiao-Qiong Xu, Chun-Rong Ta. Protective effect of extract of Astragalus on learning and memory impairments and neurons' apoptosis induced by glucocorticoids in 12-month-old male mice. Anatomical record (Hoboken, N.J. : 2007). vol 294. issue 6. 2011-10-25. PMID:21538932. |
treatment groups with ea (20 and 40 mg/kg) or rg1 (6.5 mg/kg) significantly improve learning and memory, downregulate the mrna level of caspase-3, decrease expression of caspase-3 and cytochrome c in hippocampus (ca1, ca3) and neocortex, and inhibit activity of caspase-9 and caspase-3. |
2011-10-25 |
2023-08-12 |
mouse |
| Enrico Faldini, Stijn Stroobants, Renate Lüllmann-Rauch, Matthias Eckhardt, Volkmar Gieselmann, Detlef Balschun, Rudi D'Hoog. Telencephalic histopathology and changes in behavioural and neural plasticity in a murine model for metachromatic leukodystrophy. Behavioural brain research. vol 222. issue 2. 2011-09-20. PMID:21459117. |
in addition, long term potentiation (ltp) in the ca1 region of the hippocampus, a cellular correlate of learning and memory, was also impaired in asa(-/-) mice. |
2011-09-20 |
2023-08-12 |
mouse |
| Ilhuicamina Daniel Limón, Eleazar Ramírez, Alfonso Díaz, Liliana Mendieta, Miguel Ángel Mayoral, Blanca Espinosa, Jorge Guevara, Edgar Zenten. Alteration of the sialylation pattern and memory deficits by injection of Aβ(25-35) into the hippocampus of rats. Neuroscience letters. vol 495. issue 1. 2011-09-13. PMID:21419829. |
the eight-arm maze spatial-learning and memory test indicated that the injection of aβ((25-35)) into subfield ca1 of the hp impaired both learning and memory. |
2011-09-13 |
2023-08-12 |
rat |
| Laura Mòdol, Sònia Darbra, Marc Pallarè. Neurosteroids infusion into the CA1 hippocampal region on exploration, anxiety-like behaviour and aversive learning. Behavioural brain research. vol 222. issue 1. 2011-09-02. PMID:21463656. |
these results point out the important role of the dorsal (ca1) hippocampus in several ns behavioural effects, such as exploration, anxiety, learning and memory. |
2011-09-02 |
2023-08-12 |
rat |
| Li Zhang, Yan-Hai Li, Kai Meng, Tai-Zhen Ha. Increased expression of phospho-cofilin in CA1 and subiculum areas after theta-burst stimulation of Schaffer collateral-commissural fibers in rat hippocampal slices. The Chinese journal of physiology. vol 53. issue 5. 2011-08-18. PMID:21793344. |
moreover, the ca1 and subiculum areas of the hippocampal formation possibly cooperate with each other in important physiological functions, such as learning and memory, or in pathological diseases, such as epilepsy. |
2011-08-18 |
2023-08-12 |
rat |
| Robbert G E Notenboom, Geert M J Ramakers, Amer Kamal, Berry M Spruijt, Pierre N E de Graa. Long-lasting modulation of synaptic plasticity in rat hippocampus after early-life complex febrile seizures. The European journal of neuroscience. vol 32. issue 5. 2011-03-01. PMID:20646062. |
we examined three specific measures of hippocampal plasticity in adult rats with a prior history of experimental febrile seizures: (i) activity-dependent synaptic plasticity (long-term potentiation and depression) by electrophysiological recordings of schaffer collateral/commissural-evoked field excitatory synaptic potentials in ca1 of acute hippocampal slices; (ii) morris water maze spatial learning and memory; and (iii) hippocampal mossy fiber plasticity by timm histochemistry and quantification of terminal sprouting in ca3 and the dentate gyrus. |
2011-03-01 |
2023-08-12 |
human |
| Robbert G E Notenboom, Geert M J Ramakers, Amer Kamal, Berry M Spruijt, Pierre N E de Graa. Long-lasting modulation of synaptic plasticity in rat hippocampus after early-life complex febrile seizures. The European journal of neuroscience. vol 32. issue 5. 2011-03-01. PMID:20646062. |
we found enhanced hippocampal ca1 long-term potentiation and reduced long-term depression but normal spatial learning and memory in adult rats that were subjected to experimental febrile seizures on postnatal day 10. |
2011-03-01 |
2023-08-12 |
human |
| Robbert G E Notenboom, Geert M J Ramakers, Amer Kamal, Berry M Spruijt, Pierre N E de Graa. Long-lasting modulation of synaptic plasticity in rat hippocampus after early-life complex febrile seizures. The European journal of neuroscience. vol 32. issue 5. 2011-03-01. PMID:20646062. |
we conclude that enhanced ca1 long-term potentiation and mild mossy fiber sprouting occur after experimental febrile seizures, without affecting spatial learning and memory in the morris water maze. |
2011-03-01 |
2023-08-12 |
human |
| Michael Stramiello, John J Wagne. Cocaine enhancement of long-term potentiation in the CA1 region of rat hippocampus: lamina-specific mechanisms of action. Synapse (New York, N.Y.). vol 64. issue 8. 2011-01-26. PMID:20340165. |
there is an expanding body of work characterizing dopaminergic modulation of synaptic plasticity in the hippocampus ca1 region, an area known to be involved in learning and memory. |
2011-01-26 |
2023-08-12 |
rat |
| Shufang Feng, Qiang Wang, Huaning Wang, Ye Peng, Lei Wang, Yan Lu, Tianyao Shi, Lize Xion. Electroacupuncture pretreatment ameliorates hypergravity-induced impairment of learning and memory and apoptosis of hippocampal neurons in rats. Neuroscience letters. vol 478. issue 3. 2010-10-08. PMID:20457216. |
our results showed that +gz exposure significantly caused pyramidal neuronal damage, increased neuronal apoptosis and caspase-3 activity in hippocampal ca1 region, as well as resulted in an impairment of spatial learning and memory, as compared to the sham group animals. |
2010-10-08 |
2023-08-12 |
rat |
| Ibrahim A Alhaider, Abdulaziz M Aleisa, Trinh T Tran, Karim A Alkadh. Caffeine prevents sleep loss-induced deficits in long-term potentiation and related signaling molecules in the dentate gyrus. The European journal of neuroscience. vol 31. issue 8. 2010-09-27. PMID:20384774. |
we have previously reported that caffeine prevented sleep deprivation-induced impairment of long-term potentiation (ltp) of area ca1 as well as hippocampus-dependent learning and memory performance in the radial arm water maze. |
2010-09-27 |
2023-08-12 |
rat |
| Akiko Kawashima, Tsuyoshi Harada, Hideaki Kami, Takashi Yano, Kazunori Imada, Kiyoshi Mizuguch. Effects of eicosapentaenoic acid on synaptic plasticity, fatty acid profile and phosphoinositide 3-kinase signaling in rat hippocampus and differentiated PC12 cells. The Journal of nutritional biochemistry. vol 21. issue 4. 2010-06-14. PMID:19369057. |
to evaluate the impact of eicosapentaenoic acid (epa), we orally administered highly purified ethyl epa (epa-e) to rats at a dose of 1.0 mg/g per day and measured long-term potentiation of the ca1 hippocampal region, a physiological correlate of synaptic plasticity that is thought to underlie learning and memory. |
2010-06-14 |
2023-08-12 |
rat |
| Shahla Emamian, Nasser Naghdi, Houri Sepehri, Mehrdad Jahanshahi, Yousef Sadeghi, Samira Choopan. Learning impairment caused by intra-CA1 microinjection of testosterone increases the number of astrocytes. Behavioural brain research. vol 208. issue 1. 2010-05-03. PMID:19900488. |
it is concluded that, testosterone-induced impairment in learning and memory, causes an increase in the number of astrocytes in the ca1 region of rat hippocampus. |
2010-05-03 |
2023-08-12 |
rat |
| Jian Feng, Yu Zhou, Susan L Campbell, Thuc Le, En Li, J David Sweatt, Alcino J Silva, Guoping Fa. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nature neuroscience. vol 13. issue 4. 2010-04-22. PMID:20228804. |
we generated conditional mutant mice that lack dnmt1, dnmt3a or both exclusively in forebrain excitatory neurons and found that only double knockout (dko) mice showed abnormal long-term plasticity in the hippocampal ca1 region together with deficits in learning and memory. |
2010-04-22 |
2023-08-12 |
mouse |
| Yinguo Zhang, Ning Li, Zhuo Yan. Perinatal food restriction impaired spatial learning and memory behavior and decreased the density of nitric oxide synthase neurons in the hippocampus of adult male rat offspring. Toxicology letters. vol 193. issue 2. 2010-04-08. PMID:20079408. |
the results showed fr50 reduced body weight of offspring on postnatal day (pd)1, pd7, pd10, pd14 and pd21, and this type of food restriction impaired learning and memory of adult male offspring rats (postnatal day 70) and decreased the density of nnos-positive cells in the ca1, ca3 and dg region of the hippocampus. |
2010-04-08 |
2023-08-12 |
rat |
| Parichehreh Yaghmaei, Kazem Parivar, Amirhadi Masoudi, Mehraneh Darab, Elham Amin. The effect of silybin on passive avoidance learning and pathological changes in hippocampal CA1 and DG regions in male Wistar rats offspring. Journal of Asian natural products research. vol 11. issue 6. 2010-03-23. PMID:20183284. |
given that estrogen effects on memory have been reported, silybin may cause structural changes in the hippocampal ca1 and dentate gyrus (dg) neurons and as a result it may enhance learning and memory. |
2010-03-23 |
2023-08-12 |
rat |
| Ping He, Ai-guo Wang, Tao Xia, Ping Gao, Qiang Niu, Li-juan Guo, Xue-min Che. Mechanisms underlying the developmental neurotoxic effect of PBDE-47 and the enhanced toxicity associated with its combination with PCB153 in rats. Neurotoxicology. vol 30. issue 6. 2010-03-09. PMID:19576244. |
meanwhile, the ultrastructures of neurons in the hippocampal ca1 region were observed and the learning and memory capacities were measured in these rats. |
2010-03-09 |
2023-08-12 |
rat |
| Jason A Bartos, Jason D Ulrich, Hongbin Li, Michael A Beazely, Yucui Chen, John F Macdonald, Johannes W Hel. Postsynaptic clustering and activation of Pyk2 by PSD-95. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 2. 2010-02-01. PMID:20071509. |
we show that this mechanism of pyk2 activation is critical for long-term potentiation in the hippocampus ca1 region, which is thought to underlie learning and memory. |
2010-02-01 |
2023-08-12 |
Not clear |