| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Baolan Sun, Zhengting Xia, Fuying Cai, Pengbo Wang, Meiyu Xu, Youjia W. APRIL is Involved in the Proliferation and Metastasis of Acute Lymphoblastic Leukemia Cells. Journal of pediatric hematology/oncology. vol 40. issue 8. 2019-05-13. PMID:29697578. |
april knockdown increased apoptosis (p<0.01) but suppressed cell migration along with matrix metalloproteinase-2 protein level. |
2019-05-13 |
2023-08-13 |
human |
| Amaris A Genemaras, Hayley Ennis, Brad Bradshaw, Lee Kaplan, C-Y Charles Huan. Effects of Anti-Inflammatory Agents on Expression of Early Responsive Inflammatory and Catabolic Genes in Ex Vivo Porcine Model of Acute Knee Cartilage Injury. Cartilage. vol 9. issue 3. 2019-05-13. PMID:29986604. |
the objective of this study was to investigate the effects of interleukin receptor antagonist protein (irap), hyaluronan (ha), dexamethasone (dex), and mesenchymal stem cell (msc) treatment on the expression of established genetic markers for matrix degradation, apoptosis, and inflammation in articular cartilage during the acute phase of injury. |
2019-05-13 |
2023-08-13 |
Not clear |
| Yao Jing, Lin Zhang, Zhiming Xu, Hao Chen, Shiming Ju, Jun Ding, Yan Guo, Hengli Tia. Phosphatase Actin Regulator-1 (PHACTR-1) Knockdown Suppresses Cell Proliferation and Migration and Promotes Cell Apoptosis in the bEnd.3 Mouse Brain Capillary Endothelial Cell Line. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-05-10. PMID:30772888. |
results phactr-1 knockdown suppressed bend.3 cell proliferation and migration, promoted cell apoptosis, and downregulated the expressions of migration-associated proteins, including matrix metalloproteinase (mmp)-2 and mmp-9 and upregulated apoptosis-associated proteins, including bax, bcl-2, cleaved caspase-3, and caspase-3. |
2019-05-10 |
2023-08-13 |
mouse |
| Yao Jing, Lin Zhang, Zhiming Xu, Hao Chen, Shiming Ju, Jun Ding, Yan Guo, Hengli Tia. Phosphatase Actin Regulator-1 (PHACTR-1) Knockdown Suppresses Cell Proliferation and Migration and Promotes Cell Apoptosis in the bEnd.3 Mouse Brain Capillary Endothelial Cell Line. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-05-10. PMID:30772888. |
conclusions phactr-1 was shown to have a role in the inhibition of endothelial cell proliferation and migration, promoted cell apoptosis, and regulated matrix metalloproteinases and apoptosis-associated proteins. |
2019-05-10 |
2023-08-13 |
mouse |
| Joon-Il Jun, Lester F La. Resolution of organ fibrosis. The Journal of clinical investigation. vol 128. issue 1. 2019-05-07. PMID:29293097. |
the mechanism of fibrosis resolution encompasses degradation of the fibrotic extracellular matrix as well as elimination of fibrogenic myofibroblasts through their adaptation of various cell fates, including apoptosis, senescence, dedifferentiation, and reprogramming. |
2019-05-07 |
2023-08-13 |
Not clear |
| Taís S Assmann, Mariana Recamonde-Mendoza, Bianca M de Souza, Andrea C Bauer, Daisy Crispi. MicroRNAs and diabetic kidney disease: Systematic review and bioinformatic analysis. Molecular and cellular endocrinology. vol 477. 2019-05-06. PMID:29902497. |
bioinformatic analysis indicated that these 6 mirnas are involved in pathways related to dkd pathogenesis, such as apoptosis, fibrosis, and extracellular matrix accumulation. |
2019-05-06 |
2023-08-13 |
human |
| Zhehao Shi, Wen Ye, Jiecheng Zhang, Fan Zhang, Dinglai Yu, Huajun Yu, Bicheng Chen, Mengtao Zhou, Hongwei Su. LipoxinA4 attenuates acute pancreatitis-associated acute lung injury by regulating AQP-5 and MMP-9 expression, anti-apoptosis and PKC/SSeCKS-mediated F-actin activation. Molecular immunology. vol 103. 2019-05-01. PMID:30219663. |
due to the above studies, we investigated the aquaporin, matrix metalloprotein, apoptosis and pkc/ssecks signal pathway in cellular and animal models of ap-associated lung injury following lxa4 intervention. |
2019-05-01 |
2023-08-13 |
mouse |
| Martine Perrot-Applanat, Martine Kolf-Clauw, Cécile Michel, Claire Beausolei. Alteration of mammary gland development by bisphenol a and evidence of a mode of action mediated through endocrine disruption. Molecular and cellular endocrinology. vol 475. 2019-04-29. PMID:30048677. |
several signalling pathways are consistent with the observed phenotype: proliferation and apoptosis, a focal adhesion pathway indicating changes in biomechanical properties of the extracellular matrix, and immune function. |
2019-04-29 |
2023-08-13 |
Not clear |
| Razvan Opris, Vlad Toma, Diana Olteanu, Ioana Baldea, Alina Mihaela Baciu, Florica Imre Lucaci, Alexandra Berghian-Sevastre, Corina Tatomir, Bianca Moldovan, Simona Clichici, Luminita David, Adrian Florea, Gabriela Adriana Fili. Effects of silver nanoparticles functionalized with Cornus mas L. extract on architecture and apoptosis in rat testicle. Nanomedicine (London, England). vol 14. issue 3. 2019-04-29. PMID:30657418. |
to assess ultrastructural changes, alterations in matrix metalloproteinase activity and apoptosis induced by silver nanoparticles (agnps) in the rat testicle. |
2019-04-29 |
2023-08-13 |
rat |
| Sang-Nee Tan, Sai-Peng Sim, Alan S B Kho. Matrix association region/scaffold attachment region (MAR/SAR) sequence: its vital role in mediating chromosome breakages in nasopharyngeal epithelial cells via oxidative stress-induced apoptosis. BMC molecular biology. vol 19. issue 1. 2019-04-25. PMID:30514321. |
matrix association region/scaffold attachment region (mar/sar) sequence: its vital role in mediating chromosome breakages in nasopharyngeal epithelial cells via oxidative stress-induced apoptosis. |
2019-04-25 |
2023-08-13 |
Not clear |
| Thiago H Napoleão, Lidiane P Albuquerque, Nataly Dl Santos, Isabella Cv Nova, Thâmarah A Lima, Patrícia Mg Paiva, Emmanuel V Pontua. Insect midgut structures and molecules as targets of plant-derived protease inhibitors and lectins. Pest management science. vol 75. issue 5. 2019-04-18. PMID:30306668. |
their effects on the midgut include disruption of the peritrophic matrix, brush border and secretory cell layer; induction of apoptosis and oxidative stress; interference with nutrient absorption and transport proteins; and damaging effects on symbionts. |
2019-04-18 |
2023-08-13 |
Not clear |
| Seon Goo Kim, Ji Hea Yooun, Dong Eun Kim, Eung-Seok Lee, Taeg Kyu Kwon, Shin Kim, Jong Wook Par. A novel anti-cancer agent, FPDHP, induces anoikis in various human cancer cells through activation of calpain, and downregulation of anoikis-related molecules. Journal of cellular biochemistry. vol 119. issue 7. 2019-04-12. PMID:29388704. |
anoikis is a type of apoptosis induced by inadequate cell/extracellular matrix (ecm) attachment and an attractive anti-cancer therapeutic strategy in cancer chemotherapeutic field. |
2019-04-12 |
2023-08-13 |
human |
| Ying Huang, Gui-Quan Cai, Jian-Ping Peng, Chao She. Glucocorticoids induce apoptosis and matrix metalloproteinase-13 expression in chondrocytes through the NOX4/ROS/p38 MAPK pathway. The Journal of steroid biochemistry and molecular biology. vol 181. 2019-04-12. PMID:29526705. |
glucocorticoids induce apoptosis and matrix metalloproteinase-13 expression in chondrocytes through the nox4/ros/p38 mapk pathway. |
2019-04-12 |
2023-08-13 |
Not clear |
| Jeffrey C Horowitz, Victor J Thannicka. Mechanisms for the Resolution of Organ Fibrosis. Physiology (Bethesda, Md.). vol 34. issue 1. 2019-04-10. PMID:30540232. |
herein, we review mechanisms for resolution of organ fibrosis, in particular that involving the lung, with an emphasis on the critical roles of myofibroblast apoptosis and clearance of deposited matrix. |
2019-04-10 |
2023-08-13 |
Not clear |
| M D Pinazo-Durán, K Shoaie-Nia, S M Sanz-González, J Raga-Cervera, J J García-Medina, M I López-Gálvez, D Galarreta-Mira, L Duarte, C Campos-Borges, V Zanón-Moren. Identification of new candidate genes for retinopathy in type 2 diabetics. Valencia Study on Diabetic Retinopathy (VSDR). Report number 3. Archivos de la Sociedad Espanola de Oftalmologia. vol 93. issue 5. 2019-04-03. PMID:29398232. |
to identify genes involved in the pathogenic mechanisms of non-proliferative diabetic retinopathy (npdr), among which include oxidative stress, extracellular matrix changes, and/or apoptosis, in order to evaluate the risk of developing this retinal disease in a type2 diabetic (dm2) population. |
2019-04-03 |
2023-08-13 |
Not clear |
| Yu Shi, Weihong Yan, Qiaoyan Lin, Weimin Wan. Icariin influences cardiac remodeling following myocardial infarction by regulating the CD147/MMP-9 pathway. The Journal of international medical research. vol 46. issue 6. 2019-04-03. PMID:29734850. |
the ventricular systolic function, myocardial apoptosis rate, and expression of collagen type i (col i), col iii, cd147, matrix metalloproteinase 9 (mmp-9), and tissue inhibitor of metalloproteinase 1 (timp-1) were detected by hematoxylin-eosin staining, tunel assay, and western blot. |
2019-04-03 |
2023-08-13 |
rat |
| Jie Zhou, Jianchao Sun, Dessislava Z Markova, Shuangxing Li, Christopher K Kepler, Junmin Hong, Yingjie Huang, Weijian Chen, Kang Xu, Fuxin Wei, Wei Y. MicroRNA-145 overexpression attenuates apoptosis and increases matrix synthesis in nucleus pulposus cells. Life sciences. vol 221. 2019-04-03. PMID:30797016. |
microrna-145 overexpression attenuates apoptosis and increases matrix synthesis in nucleus pulposus cells. |
2019-04-03 |
2023-08-13 |
Not clear |
| Jie Zhou, Jianchao Sun, Dessislava Z Markova, Shuangxing Li, Christopher K Kepler, Junmin Hong, Yingjie Huang, Weijian Chen, Kang Xu, Fuxin Wei, Wei Y. MicroRNA-145 overexpression attenuates apoptosis and increases matrix synthesis in nucleus pulposus cells. Life sciences. vol 221. 2019-04-03. PMID:30797016. |
multiple micrornas play crucial roles in the modulation of np cell apoptosis and matrix degradation. |
2019-04-03 |
2023-08-13 |
Not clear |
| Jie Zhou, Jianchao Sun, Dessislava Z Markova, Shuangxing Li, Christopher K Kepler, Junmin Hong, Yingjie Huang, Weijian Chen, Kang Xu, Fuxin Wei, Wei Y. MicroRNA-145 overexpression attenuates apoptosis and increases matrix synthesis in nucleus pulposus cells. Life sciences. vol 221. 2019-04-03. PMID:30797016. |
the aim of this study was to explore the role and mechanism of mir-145 in the apoptosis of np cells and in matrix metabolism in np cells. |
2019-04-03 |
2023-08-13 |
Not clear |
| Panagiotis Lepetsos, Athanasios G Papavassilio. ROS/oxidative stress signaling in osteoarthritis. Biochimica et biophysica acta. vol 1862. issue 4. 2019-03-28. PMID:26769361. |
its multi-factorial etiology includes oxidative stress and the overproduction of reactive oxygen species, which regulate intracellular signaling processes, chondrocyte senescence and apoptosis, extracellular matrix synthesis and degradation along with synovial inflammation and dysfunction of the subchondral bone. |
2019-03-28 |
2023-08-13 |
Not clear |