| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maximillian A Rogers, Elena Aikaw. Cardiovascular calcification: artificial intelligence and big data accelerate mechanistic discovery. Nature reviews. Cardiology. vol 16. issue 5. 2020-01-13. PMID:30531869. |
numerous biological processes are involved in calcific disease, including matrix remodelling, transcriptional regulation, mitochondrial dysfunction, oxidative stress, calcium and phosphate signalling, endoplasmic reticulum stress, lipid and mineral metabolism, autophagy, inflammation, apoptosis, loss of mineralization inhibition, impaired mineral resorption, cellular senescence and extracellular vesicles that act as precursors of microcalcification. |
2020-01-13 |
2023-08-13 |
human |
| Claudio Napoli, Giuditta Benincasa, Joseph Loscalz. Epigenetic Inheritance Underlying Pulmonary Arterial Hypertension. Arteriosclerosis, thrombosis, and vascular biology. vol 39. issue 4. 2020-01-13. PMID:30727752. |
in pulmonary arterial hypertension (pah), the warburg effect (glycolytic shift) and mitochondrial fission are determinants of phenotype alterations characteristic of the disease, such as proliferation, apoptosis resistance, migration, endothelial-mesenchymal transition, and extracellular matrix stiffness. |
2020-01-13 |
2023-08-13 |
Not clear |
| Zhengjie Liu, Shunguang Chen, Yezi Yang, Shengjun Lu, Xunming Zhao, Biao Hu, Hong Pe. MicroRNA‑671‑3p regulates the development of knee osteoarthritis by targeting TRAF3 in chondrocytes. Molecular medicine reports. vol 20. issue 3. 2020-01-13. PMID:31322228. |
through gain‑of‑function and loss‑of‑function experiments, mir‑671‑3p was shown to significantly affect matrix synthesis gene expression, cell proliferation, apoptosis and inflammation in chondrocytes from patients with oa. |
2020-01-13 |
2023-08-13 |
Not clear |
| Zhenghang Ge, Yi Yang, Xun Zhou, Jun Zhang, Bo Li, Xinxing Wang, Xian Lu. Overexpression of the hyperplasia suppressor gene inactivates airway fibroblasts obtained from a rat model of chronic obstructive pulmonary disease by inhibiting the Wnt signaling pathway. Molecular medicine reports. vol 20. issue 3. 2020-01-13. PMID:31322244. |
cell viability, apoptosis and the levels of matrix metallopeptidase‑9 (mmp‑9), platelet‑derived growth factor (pdgf), and transforming growth factor‑β1 (tgf‑β1) were measured via cell counting kit‑8, flow cytometry and elisa analyses, respectively, and potential mechanisms were detected by reverse transcription‑quantitative polymerase chain reaction and western blotting. |
2020-01-13 |
2023-08-13 |
rat |
| Lingling Liang, Xiaomei Wang, Yajuan Zheng, Yang Li. All‑trans‑retinoic acid modulates TGF‑β‑induced apoptosis, proliferation, migration and extracellular matrix synthesis of conjunctival fibroblasts by inhibiting PI3K/AKT signaling. Molecular medicine reports. vol 20. issue 3. 2020-01-13. PMID:31322252. |
all‑trans‑retinoic acid modulates tgf‑β‑induced apoptosis, proliferation, migration and extracellular matrix synthesis of conjunctival fibroblasts by inhibiting pi3k/akt signaling. |
2020-01-13 |
2023-08-13 |
human |
| Zahra Gray, Alijan Tabarraei, Abdolvahab Moradi, Mohamad R Kalan. M51R and Delta-M51 matrix protein of the vesicular stomatitis virus induce apoptosis in colorectal cancer cells. Molecular biology reports. vol 46. issue 3. 2020-01-07. PMID:31006094. |
m51r and delta-m51 matrix protein of the vesicular stomatitis virus induce apoptosis in colorectal cancer cells. |
2020-01-07 |
2023-08-13 |
Not clear |
| Sang-Nee Tan, Sai-Peng Si. Matrix association region/scaffold attachment region: the crucial player in defining the positions of chromosome breaks mediated by bile acid-induced apoptosis in nasopharyngeal epithelial cells. BMC medical genomics. vol 12. issue 1. 2020-01-06. PMID:30646906. |
matrix association region/scaffold attachment region: the crucial player in defining the positions of chromosome breaks mediated by bile acid-induced apoptosis in nasopharyngeal epithelial cells. |
2020-01-06 |
2023-08-13 |
Not clear |
| Renate Gehwolf, Bettina Schwemberger, Malik Jessen, Stefanie Korntner, Andrea Wagner, Christine Lehner, Nadja Weissenbacher, Herbert Tempfer, Andreas Trawege. Global Responses of Il-1β-Primed 3D Tendon Constructs to Treatment with Pulsed Electromagnetic Fields. Cells. vol 8. issue 5. 2019-12-30. PMID:31052237. |
rnaseq analysis and gene ontology assignment revealed various biological processes to be affected by pemf, including extracellular matrix remodeling and negative regulation of apoptosis. |
2019-12-30 |
2023-08-13 |
rat |
| Mohammad Bagher Mahmoudi, Ehsan Farashahi Yazd, Farhad Gharibdoost, Mohammad Hasan Sheikhha, Elham Karimizadeh, Ahmadreza Jamshidi, Mahdi Mahmoud. Overexpression of apoptosis-related protein, survivin, in fibroblasts from patients with systemic sclerosis. Irish journal of medical science. vol 188. issue 4. 2019-12-23. PMID:30761457. |
recent studies suggest that, in addition to activation and hypersecretion of matrix components, fibroblasts from patients with systemic sclerosis (ssc) are resistant to apoptosis. |
2019-12-23 |
2023-08-13 |
Not clear |
| Xue Zhang, Dong Lan, Shuhua Ning, Hongxia Jia, Sisi Y. Botulinum toxin type A prevents the phenotypic transformation of fibroblasts induced by TGF‑β1 via the PTEN/PI3K/Akt signaling pathway. International journal of molecular medicine. vol 44. issue 2. 2019-12-23. PMID:31173164. |
btxa in combination with tgf‑β1 suppressed the expression of molecules related to the extracellular matrix (ecm), epithelial‑mesenchymal transition (emt) and apoptosis. |
2019-12-23 |
2023-08-13 |
Not clear |
| Zheng Li, Xin Chen, Derong Xu, Shugang Li, Matthew T V Chan, William K K W. Circular RNAs in nucleus pulposus cell function and intervertebral disc degeneration. Cell proliferation. vol 52. issue 6. 2019-12-20. PMID:31621141. |
in this review, we summarize the current knowledge regarding the deregulation of circrnas in idd in relation to their actions on nucleus pulposus cell functions, including cell proliferation, apoptosis and extracellular matrix synthesis/degradation. |
2019-12-20 |
2023-08-13 |
Not clear |
| Jin Yong Kim, Jungyoon Ohn, Ji-Seon Yoon, Bo Mi Kang, Minji Park, Sookyung Kim, Woochan Lee, Sungjoo Hwang, Jong-Il Kim, Kyu Han Kim, Ohsang Kwo. Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy. Nature communications. vol 10. issue 1. 2019-12-16. PMID:31455775. |
in contrast to immediate destructive changes in rapidly proliferating hair matrix cells, quiescent hfscs show unexpected massive proliferation after busulfan and then undergo large-scale apoptosis following cyclophosphamide. |
2019-12-16 |
2023-08-13 |
human |
| Adina Elena Stanci. Cytokines in heart failure. Advances in clinical chemistry. vol 93. 2019-12-13. PMID:31655733. |
because the levels of circulating cytokines correlate with the development and severity of hf, these mediators may have both pathophysiological importance, through their ability to modulate inflammation, myocyte stress/stretch, myocyte injury and apoptosis, fibroblast activation and extracellular matrix remodeling, and utility as clinical predictive biomarkers. |
2019-12-13 |
2023-08-13 |
Not clear |
| Yaxin Liu, Xiaowen Wang, Liam P Coyne, Yuan Yang, Yue Qi, Frank A Middleton, Xin Jie Che. Mitochondrial carrier protein overloading and misfolding induce aggresomes and proteostatic adaptations in the cytosol. Molecular biology of the cell. vol 30. issue 11. 2019-12-09. PMID:30893019. |
we show that overloading of mitochondrial membrane carrier, but not matrix proteins, is sufficient to induce cytosolic aggresomes and apoptosis. |
2019-12-09 |
2023-08-13 |
human |
| J Sokołowska, K Urbańsk. Immunohistochemical assessment of metalloproteinases MMP2 and MMP9 expression in canine various subtypes of lymphomas in relation with proliferative and apoptotic markers. Polish journal of veterinary sciences. vol 22. issue 2. 2019-12-09. PMID:31269334. |
because of their ability to degrade signaling molecules presented in extracellular matrix, mmps contribute to tumor proliferation and apoptosis. |
2019-12-09 |
2023-08-13 |
Not clear |
| Marei Sammar, Tijana Drobnjak, Maurizio Mandala, Sveinbjörn Gizurarson, Berthold Huppertz, Hamutal Meir. Galectin 13 (PP13) Facilitates Remodeling and Structural Stabilization of Maternal Vessels during Pregnancy. International journal of molecular sciences. vol 20. issue 13. 2019-12-03. PMID:31261864. |
galectins regulate cell growth, proliferation, differentiation, apoptosis, signal transduction, mrna splicing, and interactions with the extracellular matrix. |
2019-12-03 |
2023-08-13 |
Not clear |
| Haolin Fang, Xianzhou Li, Haiming Shen, Buwei Sun, Haijun Teng, Pei L. Osteogenic protein-1 attenuates apoptosis and enhances matrix synthesis of nucleus pulposus cells under high-magnitude compression though inhibiting the p38 MAPK pathway. Bioscience reports. 2019-11-20. PMID:29440560. |
osteogenic protein-1 attenuates apoptosis and enhances matrix synthesis of nucleus pulposus cells under high-magnitude compression though inhibiting the p38 mapk pathway. |
2019-11-20 |
2023-08-13 |
Not clear |
| Charles J Malemu. MicroRNAs and Osteoarthritis. Cells. vol 7. issue 8. 2019-11-20. PMID:30071609. |
although much of the fundamental oa studies over the past 20 years identified and characterized many genes relevant to pro-inflammatory cytokines, apoptosis, and matrix metalloproteinases (mmps)/a disintegrin and metalloproteinase with thrombospondin motif (adamts), more recent studies focused on epigenetic mechanisms and the associated role of micrornas (mirs) in regulating gene expression in oa cartilage. |
2019-11-20 |
2023-08-13 |
Not clear |
| Forouzan Amerizadeh, Afsane Bahrami, Majid Khazaei, AmirReza Hesari, Majid Rezayi, Sahar Talebian, Mona Maftouh, Mehrdad Moetamani-Ahmadi, Sima Seifi, Soodabeh Shahidsales, Mona Joudi-Mashhad, Gordon A Ferns, Faezeh Ghasemi, Amir Ava. Current status and future prospects of transforming growth factor-β as a potential prognostic and therapeutic target in the treatment of breast cancer. Journal of cellular biochemistry. 2019-11-20. PMID:30672016. |
the transforming growth factor-β (tgf-β) signaling pathway is one of the important pathways involved in the cancer cell proliferation, invasion, migration, angiogenesis, apoptosis, as well as in metastasis by agitation or invasion of metastasis-related factors, including matrix metalloproteinase (mmp), epithelial-to-mesenchymal transition (emt), tumor microenvironment (tme), cancer stem cells (cscs), and cell adhesion molecules (cams). |
2019-11-20 |
2023-08-13 |
Not clear |
| Di Yang, Danjie Zhu, Shaoyu Zhu, Fabo Feng, Chen Gong, Chunmao Chen, Liang Che. Corrigendum to "17β-Estradiol/extrogen receptor β alleviates apoptosis and enhances matrix biosynthesis of nucleus pulposus cells through regulating oxidative damage under a high glucose condition" [Biomed. Pharmacother. 207 (2018) 1004-1009]. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 112. 2019-11-20. PMID:30852062. |
corrigendum to "17β-estradiol/extrogen receptor β alleviates apoptosis and enhances matrix biosynthesis of nucleus pulposus cells through regulating oxidative damage under a high glucose condition" [biomed. |
2019-11-20 |
2023-08-13 |
Not clear |