| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yingtao Yao, Jianyi Xu, Tingting Yu, Zhilong Chen, Zhiyong Xiao, Jiedong Wang, Yiqiang Hu, Yongchao Wu, Dan Zh. Flufenamic acid inhibits secondary hemorrhage and BSCB disruption after spinal cord injury. Theranostics. vol 8. issue 15. 2019-09-04. PMID:30128046. |
the matrix metalloprotease (mmp)-mediated disruption of the bscb leads to an inflammatory response, neurotoxin production and neuronal cell apoptosis. |
2019-09-04 |
2023-08-13 |
Not clear |
| Yang Yang, Huiwen Zheng, Chunhua Wang, Wanyue Xiao, Taigang Li. Predicting Apoptosis Protein Subcellular Locations based on the Protein Overlapping Property Matrix and Tri-Gram Encoding. International journal of molecular sciences. vol 20. issue 9. 2019-09-03. PMID:31083553. |
predicting apoptosis protein subcellular locations based on the protein overlapping property matrix and tri-gram encoding. |
2019-09-03 |
2023-08-13 |
Not clear |
| Yang Yang, Huiwen Zheng, Chunhua Wang, Wanyue Xiao, Taigang Li. Predicting Apoptosis Protein Subcellular Locations based on the Protein Overlapping Property Matrix and Tri-Gram Encoding. International journal of molecular sciences. vol 20. issue 9. 2019-09-03. PMID:31083553. |
in this study, a novel tri-gram encoding model is proposed, which is based on using the protein overlapping property matrix (popm) for predicting apoptosis protein subcellular location. |
2019-09-03 |
2023-08-13 |
Not clear |
| Mohammed A El-Magd, Yasser Mohamed, Eman S El-Shetry, Shafika A Elsayed, Maha Abo Gazia, Ghada A Abdel-Aleem, Noha M Shafik, Walied S Abdo, Nabila I El-Desouki, Mohamed A Basyon. Melatonin maximizes the therapeutic potential of non-preconditioned MSCs in a DEN-induced rat model of HCC. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 114. 2019-08-29. PMID:30925457. |
the obtained data revealed that administration of mel before mscs treatment without preconditioning yielded a better ameliorative effect against den-induced hepatocellular carcinoma (hcc) as evidenced by: 1) reduced serum levels of alpha fetoprotein and gamma-glutamyl transferase; 2) decreased number and area of glutathione s-transferase placental positive foci; 3) induced apoptosis (as indicated by increased cleaved caspase-3 activity, upregulated expression of proapoptotic genes bax and caspase 3 and downregulated expression of anti-apoptotic genes bcl2, survivin); 4) decreased malondialdehyde level and increased activities of superoxide dismutase, catalase, and glutathione peroxidase enzymes; and 5) reduced inflammation, angiogenesis and metastasis as indicated by downregulated expression of interleukin 1 beta, nuclear factor kappa b, vascular endothelial growth factor, and matrix metallopeptidase 9 genes and upregulated expression of metalloproteinase inhibitor 1 gene. |
2019-08-29 |
2023-08-13 |
rat |
| Atte S A Eskelinen, Mika E Mononen, Mikko S Venäläinen, Rami K Korhonen, Petri Tansk. Maximum shear strain-based algorithm can predict proteoglycan loss in damaged articular cartilage. Biomechanics and modeling in mechanobiology. vol 18. issue 3. 2019-08-28. PMID:30631999. |
by choosing the degeneration threshold suggested for inducing chondrocyte apoptosis and cartilage matrix damage, the algorithm driven by the maximum shear strain showed the most substantial fcd losses around the lesion. |
2019-08-28 |
2023-08-13 |
Not clear |
| Jun-Cheng Wu, Sheng-Zheng Luo, Ting Liu, Lun-Gen Lu, Ming-Yi X. linc-SCRG1 accelerates liver fibrosis by decreasing RNA-binding protein tristetraprolin. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 33. issue 2. 2019-08-26. PMID:30226813. |
knockdown of linc-scrg1 significantly reversed the effects of tgf-β1 on lx2, including inhibiting activation, promoting apoptosis, reducing proliferation, lessening invasion, and down-regulating genes [fibrosis-related mrna: α-smooth muscle actin ( α-sma), type i collagen, and b-cell lymphoma-2; invasion-related mrna: matrix metallopeptidase-2 ( mmp-2), mmp-9, and mmp-13; inflammation-related mrna: tnf-α, il-6, and il-10]. |
2019-08-26 |
2023-08-13 |
human |
| Indusmita Routray, Shakir Al. Boron inhibits apoptosis in hyperapoptosis condition: Acts by stabilizing the mitochondrial membrane and inhibiting matrix remodeling. Biochimica et biophysica acta. General subjects. vol 1863. issue 1. 2019-08-16. PMID:30312768. |
boron inhibits apoptosis in hyperapoptosis condition: acts by stabilizing the mitochondrial membrane and inhibiting matrix remodeling. |
2019-08-16 |
2023-08-13 |
Not clear |
| Indusmita Routray, Shakir Al. Boron inhibits apoptosis in hyperapoptosis condition: Acts by stabilizing the mitochondrial membrane and inhibiting matrix remodeling. Biochimica et biophysica acta. General subjects. vol 1863. issue 1. 2019-08-16. PMID:30312768. |
boron is a metalloid which is present in food in small amounts and is suggested here to inhibit apoptosis by stabilizing the mitochondrial membrane structure, thus preventing matrix remodeling and the release of cytochrome c, an apoptosis-inducer protein from the mitochondrion. |
2019-08-16 |
2023-08-13 |
Not clear |
| Xiaochuan Li, Shi Cheng, Yaohong Wu, Jingwei Ying, Chaofeng Wang, Tianyong Wen, Xuedong Bai, Wei Ji, Deli Wang, Dike Rua. Functional self-assembled peptide scaffold inhibits tumor necrosis factor-alpha-induced inflammation and apoptosis in nucleus pulposus cells by suppressing nuclear factor-κB signaling. Journal of biomedical materials research. Part A. vol 106. issue 4. 2019-08-15. PMID:29164771. |
the cell apoptosis rate, inflammatory mediator secretion, expression of matrix-degrading enzymes, and extracellular matrix (ecm) protein levels were evaluated. |
2019-08-15 |
2023-08-13 |
Not clear |
| Srinivasa Raju Datla, Lula L Hilenski, Bonnie Seidel-Rogol, Anna E Dikalova, Mark Harousseau, Lili Punkova, Giji Joseph, W Robert Taylor, Bernard Lassègue, Kathy K Griendlin. Poldip2 knockdown inhibits vascular smooth muscle proliferation and neointima formation by regulating the expression of PCNA and p21. Laboratory investigation; a journal of technical methods and pathology. vol 99. issue 3. 2019-08-13. PMID:30237457. |
polymerase delta-interacting protein 2 (poldip2) is a multi-functional protein with numerous roles in the vasculature, including the regulation of cell apoptosis and migration, as well as extracellular matrix deposition; however, its role in vsmc proliferation and neointimal formation is unknown. |
2019-08-13 |
2023-08-13 |
human |
| Yun-Fei Jiang, Ling-Ling Guo, Li-Wei Zhang, Yong-Xin Chu, Guang-Lang Zhu, Ye Lu, Lei Zhang, Qing-Sheng Lu, Zai-Ping Jin. Local upregulation of interleukin-1 beta in aortic dissecting aneurysm: correlation with matrix metalloproteinase-2, 9 expression and biomechanical decrease. Interactive cardiovascular and thoracic surgery. vol 28. issue 3. 2019-08-12. PMID:30169834. |
our goal was to examine whether interleukin-1 beta (il-1β) originates locally and its possible relationship with matrix metalloproteinases (mmps), apoptosis, elastin fibres and biomechanics in aortic dissecting aneurysms (das). |
2019-08-12 |
2023-08-13 |
Not clear |
| Shuaibo Huang, Nikolaos G Frangogianni. Anti-inflammatory therapies in myocardial infarction: failures, hopes and challenges. British journal of pharmacology. vol 175. issue 9. 2019-08-08. PMID:29394499. |
inflammatory cells clear the infarct of dead cells and matrix debris and activate repair by myofibroblasts and vascular cells, but may also contribute to adverse fibrotic remodelling of viable segments, accentuate cardiomyocyte apoptosis and exert arrhythmogenic actions. |
2019-08-08 |
2023-08-13 |
Not clear |
| Long Xiao, Yaohui Luo, Rongfen Tai, Ningnan Zhan. Estrogen receptor β suppresses inflammation and the progression of prostate cancer. Molecular medicine reports. vol 19. issue 5. 2019-08-01. PMID:30864712. |
in addition, the results indicated that erβ suppressed viability and migration, and induced apoptosis in prostate cancer cells, which was further demonstrated by altered expression of proliferating cell nuclear antigen, b‑cell lymphoma 2‑associated x protein, caspase‑3, e‑cadherin and matrix metalloproteinase‑2. |
2019-08-01 |
2023-08-13 |
Not clear |
| Manoj Kumar Jena, Shalini Jaswal, Sudarshan Kumar, Ashok Kumar Mohant. Molecular mechanism of mammary gland involution: An update. Developmental biology. vol 445. issue 2. 2019-07-30. PMID:30448440. |
the involution stage includes interesting physiological processes such as mec apoptosis, matrix remodeling, and the generation of cells regaining the shape of a virgin mg. signal transducer and activator of transcription 3 (stat3) is the established master regulator of this process and aberrant expression of stat3 leads to subnormal involution and may induce neoplasia. |
2019-07-30 |
2023-08-13 |
Not clear |
| Lin Lu, Jialang Hu, Qipeng Wu, Ying An, Wei Cui, Junwen Wang, Zhewei Y. Berberine prevents human nucleus pulposus cells from IL‑1β‑induced extracellular matrix degradation and apoptosis by inhibiting the NF‑κB pathway. International journal of molecular medicine. vol 43. issue 4. 2019-07-30. PMID:30816449. |
berberine prevents human nucleus pulposus cells from il‑1β‑induced extracellular matrix degradation and apoptosis by inhibiting the nf‑κb pathway. |
2019-07-30 |
2023-08-13 |
human |
| Lin Lu, Jialang Hu, Qipeng Wu, Ying An, Wei Cui, Junwen Wang, Zhewei Y. Berberine prevents human nucleus pulposus cells from IL‑1β‑induced extracellular matrix degradation and apoptosis by inhibiting the NF‑κB pathway. International journal of molecular medicine. vol 43. issue 4. 2019-07-30. PMID:30816449. |
intervertebral disc degeneration (idd) is widely considered to be one of the main causes of lower back pain, which is a chronic progressive disease closely related to inflammation, nucleus pulposus (np) cell apoptosis and extracellular matrix (ecm) degradation. |
2019-07-30 |
2023-08-13 |
human |
| R Kong, N Wang, H Luo, J L. Hesperetin Mitigates Bile Duct Ligation-Induced Liver Fibrosis by Inhibiting Extracellular Matrix and Cell Apoptosis via the TGF-β1/Smad Pathway. Current molecular medicine. vol 18. issue 1. 2019-07-25. PMID:29879887. |
hesperetin mitigates bile duct ligation-induced liver fibrosis by inhibiting extracellular matrix and cell apoptosis via the tgf-β1/smad pathway. |
2019-07-25 |
2023-08-13 |
Not clear |
| Xia Lu, Sheng Luan, Ping Dai, Kun Luo, Baolong Chen, Baoxiang Cao, Li Sun, Yunjun Yan, Jie Kon. Insights into the molecular basis of immunosuppression and increasing pathogen infection severity of ammonia toxicity by transcriptome analysis in pacific white shrimp Litopenaeus vannamei. Fish & shellfish immunology. vol 88. 2019-07-25. PMID:30885745. |
a total of 13 pathways were obtained mainly involving in this process, which mainly led to the following changes: (1) increasing the immunosuppression, anemia, endocrine dysfunction, neurotoxic effect and neuroinvasion, atherosclerosis and thrombogenesis, blood-brain barrier penetration, thyroid disorder, necrosis, inflammation, and circadian disturbance; (2) reducing the ability of vascular remodeling, angiogenesis, cell survival, migration, apoptosis, and lymph transferred to blood stream; (3) leading to cell hypertrophy, cellular shape changes, and mesangial matrix expansion. |
2019-07-25 |
2023-08-13 |
Not clear |
| Pamela K Kreeger, Laura E Strong, Kristyn S Master. Engineering Approaches to Study Cellular Decision Making. Annual review of biomedical engineering. vol 20. 2019-07-23. PMID:29328778. |
these cues may include growth factors, the extracellular matrix, cell-cell contacts, stiffness, and topography, and they are responsible for regulating cellular behaviors such as adhesion, proliferation, migration, apoptosis, and differentiation. |
2019-07-23 |
2023-08-13 |
Not clear |
| Jing-Chuan Sun, Bing Zheng, Rong-Xin Sun, Ya-Ke Meng, Shun-Min Wang, Hai-Song Yang, Yu Chen, Jian-Gang Shi, Yong-Fei Gu. MiR-499a-5p suppresses apoptosis of human nucleus pulposus cells and degradation of their extracellular matrix by targeting SOX4. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 113. 2019-07-22. PMID:30856535. |
mir-499a-5p suppresses apoptosis of human nucleus pulposus cells and degradation of their extracellular matrix by targeting sox4. |
2019-07-22 |
2023-08-13 |
human |