| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Claudio Napoli, Giuditta Benincasa, Joseph Loscalz. Epigenetic Inheritance Underlying Pulmonary Arterial Hypertension. Arteriosclerosis, thrombosis, and vascular biology. vol 39. issue 4. 2020-01-13. PMID:30727752. |
in pulmonary arterial hypertension (pah), the warburg effect (glycolytic shift) and mitochondrial fission are determinants of phenotype alterations characteristic of the disease, such as proliferation, apoptosis resistance, migration, endothelial-mesenchymal transition, and extracellular matrix stiffness. |
2020-01-13 |
2023-08-13 |
Not clear |
| Zhengjie Liu, Shunguang Chen, Yezi Yang, Shengjun Lu, Xunming Zhao, Biao Hu, Hong Pe. MicroRNA‑671‑3p regulates the development of knee osteoarthritis by targeting TRAF3 in chondrocytes. Molecular medicine reports. vol 20. issue 3. 2020-01-13. PMID:31322228. |
through gain‑of‑function and loss‑of‑function experiments, mir‑671‑3p was shown to significantly affect matrix synthesis gene expression, cell proliferation, apoptosis and inflammation in chondrocytes from patients with oa. |
2020-01-13 |
2023-08-13 |
Not clear |
| Zhenghang Ge, Yi Yang, Xun Zhou, Jun Zhang, Bo Li, Xinxing Wang, Xian Lu. Overexpression of the hyperplasia suppressor gene inactivates airway fibroblasts obtained from a rat model of chronic obstructive pulmonary disease by inhibiting the Wnt signaling pathway. Molecular medicine reports. vol 20. issue 3. 2020-01-13. PMID:31322244. |
cell viability, apoptosis and the levels of matrix metallopeptidase‑9 (mmp‑9), platelet‑derived growth factor (pdgf), and transforming growth factor‑β1 (tgf‑β1) were measured via cell counting kit‑8, flow cytometry and elisa analyses, respectively, and potential mechanisms were detected by reverse transcription‑quantitative polymerase chain reaction and western blotting. |
2020-01-13 |
2023-08-13 |
rat |
| Lingling Liang, Xiaomei Wang, Yajuan Zheng, Yang Li. All‑trans‑retinoic acid modulates TGF‑β‑induced apoptosis, proliferation, migration and extracellular matrix synthesis of conjunctival fibroblasts by inhibiting PI3K/AKT signaling. Molecular medicine reports. vol 20. issue 3. 2020-01-13. PMID:31322252. |
all‑trans‑retinoic acid modulates tgf‑β‑induced apoptosis, proliferation, migration and extracellular matrix synthesis of conjunctival fibroblasts by inhibiting pi3k/akt signaling. |
2020-01-13 |
2023-08-13 |
human |
| Zahra Gray, Alijan Tabarraei, Abdolvahab Moradi, Mohamad R Kalan. M51R and Delta-M51 matrix protein of the vesicular stomatitis virus induce apoptosis in colorectal cancer cells. Molecular biology reports. vol 46. issue 3. 2020-01-07. PMID:31006094. |
m51r and delta-m51 matrix protein of the vesicular stomatitis virus induce apoptosis in colorectal cancer cells. |
2020-01-07 |
2023-08-13 |
Not clear |
| Sang-Nee Tan, Sai-Peng Si. Matrix association region/scaffold attachment region: the crucial player in defining the positions of chromosome breaks mediated by bile acid-induced apoptosis in nasopharyngeal epithelial cells. BMC medical genomics. vol 12. issue 1. 2020-01-06. PMID:30646906. |
matrix association region/scaffold attachment region: the crucial player in defining the positions of chromosome breaks mediated by bile acid-induced apoptosis in nasopharyngeal epithelial cells. |
2020-01-06 |
2023-08-13 |
Not clear |
| Renate Gehwolf, Bettina Schwemberger, Malik Jessen, Stefanie Korntner, Andrea Wagner, Christine Lehner, Nadja Weissenbacher, Herbert Tempfer, Andreas Trawege. Global Responses of Il-1β-Primed 3D Tendon Constructs to Treatment with Pulsed Electromagnetic Fields. Cells. vol 8. issue 5. 2019-12-30. PMID:31052237. |
rnaseq analysis and gene ontology assignment revealed various biological processes to be affected by pemf, including extracellular matrix remodeling and negative regulation of apoptosis. |
2019-12-30 |
2023-08-13 |
rat |
| Mohammad Bagher Mahmoudi, Ehsan Farashahi Yazd, Farhad Gharibdoost, Mohammad Hasan Sheikhha, Elham Karimizadeh, Ahmadreza Jamshidi, Mahdi Mahmoud. Overexpression of apoptosis-related protein, survivin, in fibroblasts from patients with systemic sclerosis. Irish journal of medical science. vol 188. issue 4. 2019-12-23. PMID:30761457. |
recent studies suggest that, in addition to activation and hypersecretion of matrix components, fibroblasts from patients with systemic sclerosis (ssc) are resistant to apoptosis. |
2019-12-23 |
2023-08-13 |
Not clear |
| Xue Zhang, Dong Lan, Shuhua Ning, Hongxia Jia, Sisi Y. Botulinum toxin type A prevents the phenotypic transformation of fibroblasts induced by TGF‑β1 via the PTEN/PI3K/Akt signaling pathway. International journal of molecular medicine. vol 44. issue 2. 2019-12-23. PMID:31173164. |
btxa in combination with tgf‑β1 suppressed the expression of molecules related to the extracellular matrix (ecm), epithelial‑mesenchymal transition (emt) and apoptosis. |
2019-12-23 |
2023-08-13 |
Not clear |
| Zheng Li, Xin Chen, Derong Xu, Shugang Li, Matthew T V Chan, William K K W. Circular RNAs in nucleus pulposus cell function and intervertebral disc degeneration. Cell proliferation. vol 52. issue 6. 2019-12-20. PMID:31621141. |
in this review, we summarize the current knowledge regarding the deregulation of circrnas in idd in relation to their actions on nucleus pulposus cell functions, including cell proliferation, apoptosis and extracellular matrix synthesis/degradation. |
2019-12-20 |
2023-08-13 |
Not clear |
| Jin Yong Kim, Jungyoon Ohn, Ji-Seon Yoon, Bo Mi Kang, Minji Park, Sookyung Kim, Woochan Lee, Sungjoo Hwang, Jong-Il Kim, Kyu Han Kim, Ohsang Kwo. Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy. Nature communications. vol 10. issue 1. 2019-12-16. PMID:31455775. |
in contrast to immediate destructive changes in rapidly proliferating hair matrix cells, quiescent hfscs show unexpected massive proliferation after busulfan and then undergo large-scale apoptosis following cyclophosphamide. |
2019-12-16 |
2023-08-13 |
human |
| Adina Elena Stanci. Cytokines in heart failure. Advances in clinical chemistry. vol 93. 2019-12-13. PMID:31655733. |
because the levels of circulating cytokines correlate with the development and severity of hf, these mediators may have both pathophysiological importance, through their ability to modulate inflammation, myocyte stress/stretch, myocyte injury and apoptosis, fibroblast activation and extracellular matrix remodeling, and utility as clinical predictive biomarkers. |
2019-12-13 |
2023-08-13 |
Not clear |
| Yaxin Liu, Xiaowen Wang, Liam P Coyne, Yuan Yang, Yue Qi, Frank A Middleton, Xin Jie Che. Mitochondrial carrier protein overloading and misfolding induce aggresomes and proteostatic adaptations in the cytosol. Molecular biology of the cell. vol 30. issue 11. 2019-12-09. PMID:30893019. |
we show that overloading of mitochondrial membrane carrier, but not matrix proteins, is sufficient to induce cytosolic aggresomes and apoptosis. |
2019-12-09 |
2023-08-13 |
human |
| J Sokołowska, K Urbańsk. Immunohistochemical assessment of metalloproteinases MMP2 and MMP9 expression in canine various subtypes of lymphomas in relation with proliferative and apoptotic markers. Polish journal of veterinary sciences. vol 22. issue 2. 2019-12-09. PMID:31269334. |
because of their ability to degrade signaling molecules presented in extracellular matrix, mmps contribute to tumor proliferation and apoptosis. |
2019-12-09 |
2023-08-13 |
Not clear |
| Marei Sammar, Tijana Drobnjak, Maurizio Mandala, Sveinbjörn Gizurarson, Berthold Huppertz, Hamutal Meir. Galectin 13 (PP13) Facilitates Remodeling and Structural Stabilization of Maternal Vessels during Pregnancy. International journal of molecular sciences. vol 20. issue 13. 2019-12-03. PMID:31261864. |
galectins regulate cell growth, proliferation, differentiation, apoptosis, signal transduction, mrna splicing, and interactions with the extracellular matrix. |
2019-12-03 |
2023-08-13 |
Not clear |
| Amsterdam, Gold, Hosokawa, Yoshida, Sasson, Jung, Kotsuj. Crosstalk Among Multiple Signaling Pathways Controlling Ovarian Cell Death. Trends in endocrinology and metabolism: TEM. vol 10. issue 7. 2019-11-20. PMID:10461171. |
moreover, crosstalk between p53 and extracellular matrix components such as laminin, fibronectin and basic fibroblast growth factor, between camp- and p53-generated signals and between steroid hormones and bcl-2, can explain some of the fine tuning that controls ovarian steroidogenesis and apoptosis. |
2019-11-20 |
2023-08-12 |
human |
| Morgan, Saba, Gowe. Fibronectin influences cellular proliferation and apoptosis similarly in LNCaP and PC-3 prostate cancer cell lines. Urologic oncology. vol 5. issue 4. 2019-11-20. PMID:10869957. |
in contrast, cell proliferation, apoptosis, and bcl-2 expression showed insignificant changes in both cell lines following uncoated coverslip and collagen type 4 matrix propagation. |
2019-11-20 |
2023-08-12 |
human |
| Dean G Tang, Arthur T Porte. Apoptosis: A Current Molecular Analysis. Pathology oncology research : POR. vol 2. issue 3. 2019-11-20. PMID:11173595. |
this review provides a concise summary of the recent data on the role of oncogenes/tumor suppressor genes, cytokines and growth factors/growth factor receptors, intracellular signal transducers, cell cycle regulators, reactive oxygen species or other free radicals, extracellular matrix regulators/cell adhesion molecules, and specific endonucleases and cytoplasmic proteases (the ice family proteins) in regulating cell survival and apoptosis. |
2019-11-20 |
2023-08-12 |
human |
| William S. Dalto. The tumor microenvironment as a determinant of drug response and resistance. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy. vol 2. issue 5. 2019-11-20. PMID:11504502. |
in this case, binding extracellular matrix ligands in the tumor microenvironment may activate cell adhesion molecules, such as the integrins, and these interactions result in the activation of signal transduction pathways that block drug-induced apoptosis. |
2019-11-20 |
2023-08-12 |
Not clear |
| Michiko Nishimura, Y. Abiko, Jiro Mitamura, Tohru Kak. Effect of cell plating density and extracellular matrix protein on cell growth of epithelial rests of Malassez in vitro. Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan. vol 32. issue 2. 2019-11-20. PMID:11810436. |
these results suggest that both extracellular matrix proteins and cell-cell interactions may contribute to prevent apoptosis of erm in vitro. |
2019-11-20 |
2023-08-12 |
Not clear |