| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoli Ruan, Dongming Zhou, Rencan Nie, Ruichao Hou, Zicheng Ca. Prediction of apoptosis protein subcellular location based on position-specific scoring matrix and isometric mapping algorithm. Medical & biological engineering & computing. vol 57. issue 12. 2020-04-30. PMID:31621050. |
in this paper, a new method named ert-ect-pssm-is is proposed to predict apoptosis proteins based on the position-specific scoring matrix (pssm). |
2020-04-30 |
2023-08-13 |
Not clear |
| Eleftherios Spartalis, Michael Spartalis, Antonios Athanasiou, Stavroula A Paschou, Nikolaos Patelis, Vassilis Voudris, Dimitrios C Iliopoulo. Endothelium in Aortic Aneurysm Disease: New Insights. Current medicinal chemistry. vol 27. issue 7. 2020-04-28. PMID:31549591. |
aortic aneurysm is correlated with aortic wall deformities and injury, as a result of inflammation, matrix metalloproteinases activation, oxidative stress, and apoptosis of vascular smooth muscle cells. |
2020-04-28 |
2023-08-13 |
Not clear |
| Ilias P Doulamis, Panagiotis Konstantopoulos, Aspasia Tzani, Asier Antoranz, Angeliki Minia, Afroditi Daskalopoulou, Anestis Charalampopoulos, Leonidas Alexopoulos, Depsina N Perrea, Evangelos Menenako. Visceral white adipose tissue and serum proteomic alternations in metabolically healthy obese patients undergoing bariatric surgery. Cytokine. vol 115. 2020-04-23. PMID:30472106. |
tnf weak inducer of apoptosis (tweak) (p = 0.043), tnf related apoptosis inducing ligand (trail) (p = 0.037), growth differentiation factor-15 (gdf-15) (p = 0.04), resistin (retn) (p = 0.047), matrix metalloproteinase-9 (mmp-9) (p = 0.011) and c-terminal telopeptide (ictp) (p = 0.022) were up-regulated in the muo group in the visceral white adipose tissue. |
2020-04-23 |
2023-08-13 |
human |
| Xipeng Wang, Jianbo Fan, Xiaomin Ding, Yuyu Sun, Zhiming Cui, Wei Li. Tanshinone I Inhibits IL-1β-Induced Apoptosis, Inflammation And Extracellular Matrix Degradation In Chondrocytes CHON-001 Cells And Attenuates Murine Osteoarthritis. Drug design, development and therapy. vol 13. 2020-04-23. PMID:31686786. |
tanshinone i inhibits il-1β-induced apoptosis, inflammation and extracellular matrix degradation in chondrocytes chon-001 cells and attenuates murine osteoarthritis. |
2020-04-23 |
2023-08-13 |
Not clear |
| Gargi Gouranga Nanda, Debasmita Pankaj Alon. REVIEW: Current understanding of the pathogenesis of Fuchs' endothelial corneal dystrophy. Molecular vision. vol 25. 2020-04-22. PMID:31263352. |
this review provides a comprehensive list of known genetic players that cause fecd, and discusses the prominent pathological features that participate in disease progression, such as channel dysfunction, abnormal extracellular matrix deposition, rna toxicity, oxidative stress, and apoptosis. |
2020-04-22 |
2023-08-13 |
Not clear |
| Dong Ryeol Ryu, Mi Ra Yu, Kyoung Hye Kong, Hyoungnae Kim, Soon Hyo Kwon, Jin Seok Jeon, Dong Cheol Han, Hyunjin No. Sirt1-hypoxia-inducible factor-1α interaction is a key mediator of tubulointerstitial damage in the aged kidney. Aging cell. vol 18. issue 2. 2020-04-20. PMID:30614190. |
kidneys from aged mice showed increased infiltration of cd68-positive macrophages, higher expression of extracellular matrix (ecm) proteins, and more apoptosis than young controls. |
2020-04-20 |
2023-08-13 |
mouse |
| Chun-Ching Chiu, Jer-Min Lin, Li-Yi Wu, Tsai-Ching Hsu, Bor-Show Tzan. The Beneficial Effects of Raffinee in Permanent Occulted Stroke Mice. Journal of medicinal food. vol 22. issue 12. 2020-04-20. PMID:31545135. |
this study reveals the advantageous effects of raffinee on pc12 cells by decreasing hypoxia-induced apoptosis in mice with permanent middle cerebral artery occlusion (pmcao) by increasing the levels of neurotrophic factors such as s100β, reducing serum inflammatory factors such as matrix metalloproteinases (mmp)-9/mmp-2 ratio, tumor necrosis factor- |
2020-04-20 |
2023-08-13 |
mouse |
| Xiaoping Hu, Huagang Liu, Zhiwei Wang, Zhipeng Hu, Luocheng L. miR-200a Attenuated Doxorubicin-Induced Cardiotoxicity through Upregulation of Nrf2 in Mice. Oxidative medicine and cellular longevity. vol 2019. 2020-04-20. PMID:31781322. |
moreover, mir-200a reduced oxidative stress and cardiac apoptosis without affecting matrix metalloproteinase and inflammatory factors in mice with acute dox injection. |
2020-04-20 |
2023-08-13 |
mouse |
| Talveen S Purba, Kayumba Ng'andu, Lars Brunken, Eleanor Smart, Ellen Mitchell, Nashat Hassan, Aaron O'Brien, Charlotte Mellor, Jennifer Jackson, Asim Shahmalak, Ralf Pau. CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane-induced alopecia. EMBO molecular medicine. vol 11. issue 10. 2020-04-16. PMID:31512803. |
paclitaxel and docetaxel induced massive mitotic defects and apoptosis in transit amplifying hair matrix keratinocytes and within epithelial stem/progenitor cell-rich outer root sheath compartments, including within keratin 15+ cell populations, thus implicating direct damage to stem/progenitor cells as an explanation for the severity and permanence of taxane chemotherapy-induced alopecia. |
2020-04-16 |
2023-08-13 |
human |
| Y-X Wang, J-R Ma, S-Q Wang, Y-Q Zeng, C-Y Zhou, Y-H Ru, L Zhang, Z-G Lu, M-H Wu, H L. Utilizing integrating network pharmacological approaches to investigate the potential mechanism of Ma Xing Shi Gan Decoction in treating COVID-19. European review for medical and pharmacological sciences. vol 24. issue 6. 2020-04-15. PMID:32271454. |
gene ontology functional enrichment analysis demonstrated that the biological processes altered within the body after taking mxsgd were closely related to the regulation of such processes as the acute inflammatory response, chemokine production, vascular permeability, response to oxygen radicals, oxidative stress-induced apoptosis, t cell differentiation involved in the immune response, immunoglobulin secretion, and extracellular matrix disassembly. |
2020-04-15 |
2023-08-13 |
Not clear |
| Christian Vogeley, Charlotte Esser, Thomas Tüting, Jean Krutmann, Thomas Haarmann-Stemman. Role of the Aryl Hydrocarbon Receptor in Environmentally Induced Skin Aging and Skin Carcinogenesis. International journal of molecular sciences. vol 20. issue 23. 2020-04-14. PMID:31795255. |
in contrast, a chronic activation of cutaneous ahr signaling critically contributes to premature aging and the development of neoplasms by affecting metabolism, extracellular matrix remodeling, inflammation, pigmentation, dna repair, and apoptosis. |
2020-04-14 |
2023-08-13 |
Not clear |
| Moritz Lindquist Liljeqvist, Linnea Eriksson, Christina Villard, Mariette Lengquist, Malin Kronqvist, Rebecka Hultgren, Joy Ro. Dipeptidyl peptidase-4 is increased in the abdominal aortic aneurysm vessel wall and is associated with aneurysm disease processes. PloS one. vol 15. issue 1. 2020-04-14. PMID:31971988. |
dipeptidyl peptidase-4 (dpp4)-inhibitors, used clinically to treat type 2 diabetes, have in murine models been shown to attenuate aneurysm formation and decrease aortic wall matrix degradation, inflammation and apoptosis. |
2020-04-14 |
2023-08-13 |
human |
| Zi-Jian Yang, Jun-Yao Huang, Ye-Fei Gao, Jun-Yao Huang, Wen-Ji Huang, Jun-Yao Huang, Shi-Lei Xu, Jun-Yao Huang, Jing-Jing Jin, Jun-Yao Huang, Ye-Dong Wan, Jun-Yao Huang, Ming Yan, Jun-Yao Huang, Hong-Jiao Mao, Jun-Yao Huang, Yun Zhang, Jun-Yao Huan. [Effects of bergapten on damages of osteocytes MLO-Y4 induced by TCP wear particles and its mechanism]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 35. issue 6. 2020-04-14. PMID:32239867. |
mtt assay and calcein-am staining were used to determine the viability of mlo-y4 cells; hoechst 33342 staining and the flow cytometry were applied to detect the apoptosis of mlo-y4; real-time pcr was performed to examine the mrna levels of dentin matrix protein1 (dmp-1), sclerostin (sost) and fibroblast growth factor23 (fgf23); western blot was performed to examine protein expressions of glucose-regulated protein 78 (grp78), protein kinase r-like er kinase (perk) phospho-perk (p-perk), eukaryotic initiation factor 2α (eif2α), phospho-eif2α (p-eif2α), activating transcription factor 4 (aft4), c/ebp homologous protein (chop) and caspase-3 in mlo-y4 cells. |
2020-04-14 |
2023-08-13 |
Not clear |
| Yong-Jie Li, Yue Wang, Yi-Ying Wan. MicroRNA-99b suppresses human cervical cancer cell activity by inhibiting the PI3K/AKT/mTOR signaling pathway. Journal of cellular physiology. vol 234. issue 6. 2020-04-13. PMID:30480801. |
next, alteration of mir-99b expression in cervical cancer was conducted to evaluate levels of pi3k, akt, mtor, p70s6k matrix metallopeptidase 2, epithelial cell adhesion molecule, and intercellular adhesion molecule 1, as well as the effect of mir-99b on cell proliferation, invasion, migration, cell cycle distribution, and apoptosis. |
2020-04-13 |
2023-08-13 |
human |
| Yan Gong, Yuhan Yang, Sufang Tian, Honglei Che. Different Role of Caveolin-1 Gene in the Progression of Gynecological Tumors. Asian Pacific journal of cancer prevention : APJCP. vol 20. issue 11. 2020-04-13. PMID:31759347. |
the role of cav-1 in tumorigenesis, including dysregulation of cell cycle, apoptosis and autophagy, adhesion, invasion, and metastasis, such as the formation of invadopodia and matrix metalloproteinase degradation are presented in detail. |
2020-04-13 |
2023-08-13 |
Not clear |
| Honghai Wang, Jun Mao, Yuhong Huang, Jun Zhang, Lin Zhong, Ying Wu, He Huang, Jiayu Yang, Yuanyi Wei, Jianwu Tan. Prognostic roles of miR-124-3p and its target ANXA7 and their effects on cell migration and invasion in hepatocellular carcinoma. International journal of clinical and experimental pathology. vol 13. issue 3. 2020-04-11. PMID:32269673. |
in vitro, up-regulation of mir-124-3p promotes apoptosis and inhibits migration and invasion of hca-f. bcl-2 correlates x protein (bax) protein level was up-regulated, while anxa7, b-cell lymphoma-2 (bcl-2), matrix metalloproteinase (mmp-9) and c-x-c motif chemokine 12 (cxcl12) protein levels were suppressed relative to mir-124-3p over-expression. |
2020-04-11 |
2023-08-13 |
Not clear |
| Ziming Liu, Zhiwen Zhang, Ali Zhang, Fan Zhang, Wennan Du, Yongqiang Zhang, Rongfeng Zhang, Jiagang Xu, Xiangkun Wu, Chengmin Zhang, Ning Li, Qi Tan, Wei Huan. Osteogenic protein-1 alleviates high glucose microenvironment-caused degenerative changes in nucleus pulposus cells. Bioscience reports. vol 39. issue 4. 2020-04-09. PMID:30872412. |
np cell apoptosis ratio, caspase-3/9 activity, expression of apoptosis-related molecules (bcl-2, bax, and caspase-3), matrix macromolecules (aggrecan and collagen ii), and matrix remodeling enzymes (mmp-3, mmp-13, and adamts-4), and immuno-staining of np matrix proteins (aggrecan and collagen ii) were evaluated. |
2020-04-09 |
2023-08-13 |
rat |
| Bo-Wei Wang, Yi Jiang, Zi-Long Yao, Pei-Sheng Chen, Bin Yu, Sheng-Nan Wan. Aucubin Protects Chondrocytes Against IL-1β-Induced Apoptosis In Vitro And Inhibits Osteoarthritis In Mice Model. Drug design, development and therapy. vol 13. 2020-04-06. PMID:31631977. |
chondrocyte apoptosis has also been strongly correlated with the severity of cartilage damage and matrix depletion in an osteoarthritis (oa) joint. |
2020-04-06 |
2023-08-13 |
mouse |
| Fuding Chen, Gang Du, Meishu Shih, Hongjiang Yuan, Peng Bao, Sheng Shi, Yong Cang, Zhen Zhan. Safe and effective subcutaneous adipolysis in minipigs by a collagenase derivative. PloS one. vol 14. issue 12. 2020-04-02. PMID:31891643. |
adipocytes attached to the extracellular matrix (ecm) mainly consist of collagen in adipose tissues, while the degradation of ecm by collagenase induces the apoptosis of adipocytes, leading to a decrease in local subcutaneous adipose. |
2020-04-02 |
2023-08-13 |
Not clear |
| Kara Pham, Emma Turian, Kai Liu, Shuwang Li, John Lowengru. Nonlinear studies of tumor morphological stability using a two-fluid flow model. Journal of mathematical biology. vol 77. issue 3. 2020-03-27. PMID:29546457. |
we demonstrate that tumor evolution is regulated by a reduced set of nondimensional parameters that characterize apoptosis, cell-cell/cell-extracellular matrix adhesion, vascularization and the ratio of tumor and host viscosities. |
2020-03-27 |
2023-08-13 |
Not clear |