| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pingping Hu, Dong Fang, Liping Shen, Huangao Zhou, Rui Shao, Miao Chen, Chenghu Yao, Yang Shi, Qian Che. Fibrin matrix containing high-dose calcitriol promotes the apoptosis of gastric cancer cells by sustainably releasing calcitrol and D-dimer. Journal of biomaterials applications. vol 34. issue 4. 2020-09-09. PMID:31195918. |
fibrin matrix containing high-dose calcitriol promotes the apoptosis of gastric cancer cells by sustainably releasing calcitrol and d-dimer. |
2020-09-09 |
2023-08-13 |
Not clear |
| Joon Seok Lee, Jong Seong Kim, Jeong Woo Lee, Kang Young Choi, Jung Dug Yang, Byung Chae Cho, Eun Jung Oh, Tae Jung Kim, Ung Hyun Ko, Jennifer H Shin, Sewha Jeon, Yong Jig Lee, Ho Yun Chun. Effect of Keratinocytes on Myofibroblasts in Hypertrophic Scars. Aesthetic plastic surgery. vol 43. issue 5. 2020-09-04. PMID:31346713. |
myofibroblasts play a central role in matrix formation and wound contraction during wound healing and undergo apoptosis at the end of the healing. |
2020-09-04 |
2023-08-13 |
Not clear |
| Yue Hu, Zhipeng Gui, Yuning Zhou, Lunguo Xia, Kaili Lin, Yuanjin X. Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages. Free radical biology & medicine. vol 145. 2020-09-02. PMID:31550528. |
cartilage matrix degradation, production of proinflammatory mediators, chondrocyte apoptosis and activation of macrophages in the synovial are involved in oa pathogenesis. |
2020-09-02 |
2023-08-13 |
rat |
| Li Wenzhao, Ni Jiangdong, Song Deye, Ding Muliang, Wang Junjie, Huang Xianzhe, Yan Mingming, Huang Ju. Dual regulatory roles of HMGB1 in inflammatory reaction of chondrocyte cells and mice. Cell cycle (Georgetown, Tex.). vol 18. issue 18. 2020-09-01. PMID:31313630. |
in the current study, we used quantitative real-time pcr(q-pcr) to detect them rna levels of collagen type ii alpha 1(col2a1), aggrecan, mmp3(matrix metallopeptidase 3), mmp13, adamts4 and adamts5; enzyme-linked immunosorbent assay(elisa) was used to detect the content of il-1β and calpain protein; cell apoptosis was evaluated by terminal deoxynucleotidyl transferase-mediated dutp-biotin nick end labeling(tunel) assay and flow cytometryanalysis; western blot and immunofluorescence assays were applied to assess the expression of hmgb1; lastly autophagic activity was mainly verified by monodansylcadaverine (mdc) staining. |
2020-09-01 |
2023-08-13 |
mouse |
| Y Kakiuchi, T Yurube, K Kakutani, T Takada, M Ito, Y Takeoka, Y Kanda, S Miyazaki, R Kuroda, K Nishid. Pharmacological inhibition of mTORC1 but not mTORC2 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism through Akt and autophagy induction. Osteoarthritis and cartilage. vol 27. issue 6. 2020-08-31. PMID:30716534. |
pharmacological inhibition of mtorc1 but not mtorc2 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism through akt and autophagy induction. |
2020-08-31 |
2023-08-13 |
human |
| Chia-Ter Chao, Hsiang-Yuan Yeh, Tzu-Hang Yuan, Chih-Kang Chiang, Huei-Wen Che. MicroRNA-125b in vascular diseases: An updated systematic review of pathogenetic implications and clinical applications. Journal of cellular and molecular medicine. vol 23. issue 9. 2020-08-28. PMID:31301111. |
specific mirnas are involved in the differentiation, phenotypic switch, proliferation, apoptosis, cytokine production and matrix deposition of endothelial cells and/or vascular smooth muscle cells. |
2020-08-28 |
2023-08-13 |
Not clear |
| Surinder M Soond, Maria V Kozhevnikova, Andrey A Zamyatni. 'Patchiness' and basic cancer research: unravelling the proteases. Cell cycle (Georgetown, Tex.). vol 18. issue 15. 2020-08-27. PMID:31213124. |
while extracellular cathepsins are generally believed to be of central importance in tumour progression, through their ability to modulate the architecture of the extracellular matrix, intracellular cathepsins have been established as being of extreme significance in mediating cell death through apoptosis. |
2020-08-27 |
2023-08-13 |
Not clear |
| Jun Long, Xiaobo Wang, Xianfa Du, Hehai Pan, Jianru Wang, Zemin Li, Hui Liu, Xudong Li, Zhaomin Zhen. JAG2/Notch2 inhibits intervertebral disc degeneration by modulating cell proliferation, apoptosis, and extracellular matrix. Arthritis research & therapy. vol 21. issue 1. 2020-08-27. PMID:31619270. |
jag2/notch2 inhibits intervertebral disc degeneration by modulating cell proliferation, apoptosis, and extracellular matrix. |
2020-08-27 |
2023-08-13 |
Not clear |
| Lei Li, Guohua Lv, Bing Wang, Lei Kuan. XIST/miR-376c-5p/OPN axis modulates the influence of proinflammatory M1 macrophages on osteoarthritis chondrocyte apoptosis. Journal of cellular physiology. vol 235. issue 1. 2020-08-25. PMID:31215024. |
in the present study, we reveal that the overexpression of osteopontin (opn), a cytokine, and a matrix protein involved in arthritis and chondrocyte apoptosis in oa, could exacerbate the inflammatory microenvironment in oa via promoting the production of proinflammation cytokines and the levels of degradative enzymes in m1 macrophages, therefore, enhancing the cytotoxicity of m1 macrophage on chondrocytes. |
2020-08-25 |
2023-08-13 |
Not clear |
| Suravi Majumder, Lu Ren, Sathnur Pushpakumar, Utpal Se. Hydrogen sulphide mitigates homocysteine-induced apoptosis and matrix remodelling in mesangial cells through Akt/FOXO1 signalling cascade. Cellular signalling. vol 61. 2020-08-21. PMID:31085234. |
hydrogen sulphide mitigates homocysteine-induced apoptosis and matrix remodelling in mesangial cells through akt/foxo1 signalling cascade. |
2020-08-21 |
2023-08-13 |
Not clear |
| Changli Zhang, Madeline P Smith, George K Zhou, Alon Lai, Robert C Hoy, Victoria Mroz, Olivia M Torre, Damien M Laudier, Elizabeth W Bradley, Jennifer J Westendorf, James C Iatridis, Svenja Illien-Jünge. Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice. Cell death & disease. vol 10. issue 10. 2020-08-20. PMID:31582730. |
the akt signaling pathway regulates cellularity and matrix production in ivds and its inactivation is known to contribute to a catabolic shift and increased cell loss via apoptosis. |
2020-08-20 |
2023-08-13 |
mouse |
| Svetlana Farberov, Raghavendra Basavaraja, Rina Meida. Thrombospondin-1 at the crossroads of corpus luteum fate decisions. Reproduction (Cambridge, England). vol 157. issue 3. 2020-08-19. PMID:30566900. |
thbs1 interacts both synergistically and antagonistically with other essential luteal factors, such as fibroblast growth factor 2, transforming growth factor beta1 and serpin family e member 1, to promote vascular instability, apoptosis and matrix remodeling during luteal regression. |
2020-08-19 |
2023-08-13 |
Not clear |
| V K Khavinson, N S Linkova, A S Diatlova, E O Gutop, O A Orlov. [Short peptides: regulation of skin function during aging.] Advances in gerontology = Uspekhi gerontologii. vol 33. issue 1. 2020-08-18. PMID:32362083. |
polyfunctional peptides (acsdkp, ked, aedg, aed) have geroprotective properties, slow apoptosis and stimulate skin cell proliferation, also increase functional activity of skin fibroblasts, normalize intracellular matrix hemostasis. |
2020-08-18 |
2023-08-13 |
Not clear |
| Weifang Liu, Minglian Luo, Li Zou, Xiaoxia Liu, Rongli Wang, Hui Tao, Di Wu, Wen Zhang, Qingqing Luo, Yin Zha. uNK cell-derived TGF-β1 regulates the long noncoding RNA MEG3 to control vascular smooth muscle cell migration and apoptosis in spiral artery remodeling. Journal of cellular biochemistry. vol 120. issue 9. 2020-08-17. PMID:31099432. |
the results of these analyses showed that treating the vsmc with unk cell-derived supernatant or recombinant human tgf-β1 promoted meg3 and matrix metalloprotease 2 expression and vsmc apoptosis and migration, and suppressed vsmc proliferation. |
2020-08-17 |
2023-08-13 |
human |
| Lior Ofer, Maitena Dumont, Alexander Rack, Paul Zaslansky, Ron Shaha. New insights into the process of osteogenesis of anosteocytic bone. Bone. vol 125. 2020-08-03. PMID:31085351. |
in this process osteoblasts become entrapped in the bone matrix (as occurs in osteogenesis of osteocytic bone), but then undergo apoptosis, become mineralized and end up as part of the mineralized bone matrix. |
2020-08-03 |
2023-08-13 |
zebrafish |
| Juliana Falero-Perez, Nader Sheibani, Christine M Sorenso. Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells. PloS one. vol 15. issue 5. 2020-07-31. PMID:32365083. |
bim is a pro-apoptotic protein that modulates not only apoptosis but also various cellular functions such as migration and extracellular matrix protein expression. |
2020-07-31 |
2023-08-13 |
mouse |
| Vladimir Mashanov, Jennifer Akiona, Maleana Khoury, Jacob Ferrier, Robert Reid, Denis Jacob Machado, Olga Zueva, Daniel Janie. Active Notch signaling is required for arm regeneration in a brittle star. PloS one. vol 15. issue 5. 2020-07-31. PMID:32396580. |
in the regrowing arm, notch regulates the composition of the extracellular matrix, cell migration, proliferation, and apoptosis, as well as components of the innate immune response. |
2020-07-31 |
2023-08-13 |
Not clear |
| Ana Corachán, Hortensia Ferrero, Julia Escrig, Javier Monleon, Amparo Faus, Irene Cervelló, Antonio Pellice. Long-term vitamin D treatment decreases human uterine leiomyoma size in a xenograft animal model. Fertility and sterility. vol 113. issue 1. 2020-07-22. PMID:31739978. |
to study the effects of short- and long-term vitamin d treatment on uterine leiomyomas in vivo through cell proliferation, extracellular matrix (ecm) degradation, and apoptosis. |
2020-07-22 |
2023-08-13 |
human |
| Nuria Perretta-Tejedor, José M Muñoz-Félix, Annette Düwel, Yaremi Quiros-Luis, José L Fernández-Martín, Ana I Morales, Francisco J López-Hernández, José M López-Novoa, Carlos Martínez-Salgad. Cardiotrophin-1 opposes renal fibrosis in mice: Potential prevention of chronic kidney disease. Acta physiologica (Oxford, England). vol 226. issue 2. 2020-07-21. PMID:30589223. |
chronic kidney disease is characterized by tubulointerstitial fibrosis involving inflammation, tubular apoptosis, fibroblast proliferation and extracellular matrix accumulation. |
2020-07-21 |
2023-08-13 |
mouse |
| B Stojanović, C Bauer, C Stotter, T Klestil, S Nehrer, F Franek, M Rodríguez Ripol. Tribocorrosion of a CoCrMo alloy sliding against articular cartilage and the impact of metal ion release on chondrocytes. Acta biomaterialia. vol 94. 2020-07-21. PMID:31226479. |
since the presence of metal ions in the cartilage matrix can potentially lead to cell apoptosis, the metabolic activity of human osteoarthritic chondrocytes (2d-cultures) was investigated in the presence of phosphate buffered saline containing metal ions using xtt-assay. |
2020-07-21 |
2023-08-13 |
human |