| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xi Sun, Lijun Gan, Nan Li, Shuyi Sun, Na L. Tabersonine ameliorates osteoblast apoptosis in rats with dexamethasone-induced osteoporosis by regulating the Nrf2/ROS/Bax signalling pathway. AMB Express. vol 10. issue 1. 2020-10-01. PMID:32915329. |
tab increased cell viability and alp activity, and reduced the mitochondrial superoxide, reactive oxygen species and matrix metalloproteinase levels and osteoblast apoptosis. |
2020-10-01 |
2023-08-13 |
rat |
| Yasuyoshi Miyata, Kensuke Mitsunari, Asai Akihiro, Shin-Ichi Watanabe, Yasushi Mochizuki, Hideki Saka. Smoking-induced changes in cancer-related factors in patients with upper tract urothelial cancer. Molecular and clinical oncology. vol 3. issue 2. 2020-10-01. PMID:25798255. |
we investigated the associations between smoking status and cancer-related factors, including cancer cell proliferation, apoptosis, angiogenesis, lymphangiogenesis and expression of vascular endothelial growth factor-a and -c, matrix metalloproteinase (mmp)-2 and -9, cyclooxygenase (cox)-2 and urokinase-type plasminogen activator, in patients with utuc. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yunhua Tang, Xiangyang Zhang, Fan Qi, Mingfeng Chen, Yuan Li, Longfei Liu, Wei He, Zhuo Li, Xiongbing Z. Afatinib inhibits proliferation and invasion and promotes apoptosis of the T24 bladder cancer cell line. Experimental and therapeutic medicine. vol 9. issue 5. 2020-10-01. PMID:26136904. |
mtt assay was used to estimate the proliferation of the t24 cells; flow cytometric analysis was used to estimate the effect of afatinib on t24 cell apoptosis; cell invasion ability was assessed by a transwell invasion assay; and western blot analysis was used to detect the expression of bcl-2, bax, akt, extracellular-signal-regulated kinase (erk)1/2, matrix metalloproteinase (mmp)-2 and mmp-9. |
2020-10-01 |
2023-08-13 |
human |
| Antonietta Restuccia, Ye F Tian, Joel H Collier, Gregory A Hudall. Self-assembled glycopeptide nanofibers as modulators of galectin-1 bioactivity. Cellular and molecular bioengineering. vol 8. issue 3. 2020-10-01. PMID:26495044. |
galectin bioactivity is mediated by specific non-covalent interactions with cell-surface and extracellular matrix (ecm) glycoproteins, which can enhance or inhibit signaling events that influence various cellular behaviors, including adhesion, proliferation, differentiation, and apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Shao-Qing Chen, Jian-Ping Lin, Qi-Kai Zheng, Shui-Jin Chen, Ming Li, Xian-Zhao Lin, Shi-Zhong Wan. Protective effects of paeoniflorin against FasL-induced apoptosis of intervertebral disc annulus fibrosus cells via Fas-FasL signalling pathway. Experimental and therapeutic medicine. vol 10. issue 6. 2020-10-01. PMID:26668640. |
in the present study, we demonstrate that the degeneration of intervertebral discs is caused by ageing and apoptosis of matrix cells. |
2020-10-01 |
2023-08-13 |
rat |
| Zhirong Wang, Genlin Wang, Xuesong Zhu, Dechun Geng, Huilin Yan. Interleukin-2 is upregulated in patients with a prolapsed lumbar intervertebral disc and modulates cell proliferation, apoptosis and extracellular matrix metabolism of human nucleus pulposus cells. Experimental and therapeutic medicine. vol 10. issue 6. 2020-10-01. PMID:26668654. |
interleukin-2 is upregulated in patients with a prolapsed lumbar intervertebral disc and modulates cell proliferation, apoptosis and extracellular matrix metabolism of human nucleus pulposus cells. |
2020-10-01 |
2023-08-13 |
human |
| Zhirong Wang, Genlin Wang, Xuesong Zhu, Dechun Geng, Huilin Yan. Interleukin-2 is upregulated in patients with a prolapsed lumbar intervertebral disc and modulates cell proliferation, apoptosis and extracellular matrix metabolism of human nucleus pulposus cells. Experimental and therapeutic medicine. vol 10. issue 6. 2020-10-01. PMID:26668654. |
the present study aimed to determine the expression levels of il-2 in the nucleus pulposus (np) tissues of patients with a prolapsed lumbar intervertebral disc; and to observe the changes in cell proliferation, apoptosis, extracellular matrix (ecm) metabolism and p38 mitogen-activated protein kinase (mapk) signaling in human np cells (hnpcs) following treatment with il-2. |
2020-10-01 |
2023-08-13 |
human |
| Tingting Ye, Jiadong Su, Chaohao Huang, Dinglai Yu, Shengjie Dai, Xince Huang, Bicheng Chen, Mengtao Zho. Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells. OncoTargets and therapy. vol 9. 2020-10-01. PMID:28003763. |
in pc, isoorientin strongly inhibited the survival of the cells, induced cell apoptosis, and decreased its malignancy by reversing the expression of epithelial-mesenchymal transition and matrix metalloproteinase and decreased vascular endothelial growth factor expression. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xinghuo Wu, Yu Song, Wei Liu, Kun Wang, Yong Gao, Shuai Li, Zhenfeng Duan, Zengwu Shao, Shuhua Yang, Cao Yan. IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells. Cell death discovery. vol 3. 2020-10-01. PMID:28149534. |
iapp modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells. |
2020-10-01 |
2023-08-13 |
human |
| Jing Shi, Xu Zhang, Taoping Shi, Hongzhao L. Antitumor effects of curcumin in human bladder cancer Oncology letters. vol 14. issue 1. 2020-10-01. PMID:28693289. |
the present study confirmed that curcumin is able to inhibit cell migration and promote apoptosis of bladder cancer through suppression of matrix metalloproteinase signaling pathways |
2020-10-01 |
2023-08-13 |
human |
| Qing-Yang Feng, Zi-Xuan Hu, Xi-Ling Song, Hong-Wei Pa. Aberrant expression of genes and proteins in pterygium and their implications in the pathogenesis. International journal of ophthalmology. vol 10. issue 6. 2020-10-01. PMID:28730091. |
in this review, we summarize the aberrant expression of a range of genes and proteins in pterygium compared with normal conjunctiva or cornea, including growth factors, matrix metalloproteinases and tissue inhibitors of metalloproteinases, interleukins, tumor suppressor genes, proliferation related proteins, apoptosis related proteins, cell adhesion molecules, extracellular matrix proteins, heat shock proteins and tight junction proteins. |
2020-10-01 |
2023-08-13 |
human |
| Xinyu Yang, Yang Li, Yanda Li, Xiaomeng Ren, Xiaoyu Zhang, Dan Hu, Yonghong Gao, Yanwei Xing, Hongcai Shan. Oxidative Stress-Mediated Atherosclerosis: Mechanisms and Therapies. Frontiers in physiology. vol 8. 2020-10-01. PMID:28878685. |
atherogenesis, the formation of atherosclerotic plaques, is a complex process that involves several mechanisms, including endothelial dysfunction, neovascularization, vascular proliferation, apoptosis, matrix degradation, inflammation, and thrombosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| N Woolf, B E Pearson, P A Bondzie, R D Meyer, M Lavaei, A C Belkina, V Chitalia, N Rahim. Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy. Oncogenesis. vol 6. issue 9. 2020-10-01. PMID:28920928. |
adhesion to extracellular matrix (ecm) is crucially important for survival of normal epithelial cells as detachment from ecm triggers specific apoptosis known as anoikis. |
2020-10-01 |
2023-08-13 |
mouse |
| Qin Tian, Yifei Wang, Qiong Zhang, Jun Luo, He Jiang, Boyue Zhang, Mingzhu Mei, Fan Wu, Yuting Wu, Jiaojiao Peng, Teng Long, Yongwen Luo, Xiaofeng Gu. Phosphoprotein Gene Contributes to the Enhanced Apoptosis Induced by Wild-Type Rabies Virus GD-SH-01 Frontiers in microbiology. vol 8. 2020-10-01. PMID:28928726. |
phosphoprotein gene contributes to the enhanced apoptosis induced by wild-type rabies virus gd-sh-01 previous research demonstrated that the matrix protein (m) and glycoprotein (g) of attenuated rabies virus (rabv) strains are involved in the induction of host cell apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| A G D Vianna, C P Sanches, F C Barret. Review article: effects of type 2 diabetes therapies on bone metabolism. Diabetology & metabolic syndrome. vol 9. 2020-10-01. PMID:29021829. |
type 2 diabetes mellitus (t2dm) compromises bone microarchitecture by inducing abnormal bone cell function and matrix structure with increased osteoblast apoptosis, diminished osteoblast differentiation, and enhanced osteoclast-mediated bone resorption. |
2020-10-01 |
2023-08-13 |
Not clear |
| Shuan Liu, Hongping Yang, Bing Hu, Mingyong Zhan. Sirt1 regulates apoptosis and extracellular matrix degradation in resveratrol-treated osteoarthritis chondrocytes via the Wnt/β-catenin signaling pathways. Experimental and therapeutic medicine. vol 14. issue 5. 2020-10-01. PMID:29201214. |
sirt1 regulates apoptosis and extracellular matrix degradation in resveratrol-treated osteoarthritis chondrocytes via the wnt/β-catenin signaling pathways. |
2020-10-01 |
2023-08-13 |
Not clear |
| Shuan Liu, Hongping Yang, Bing Hu, Mingyong Zhan. Sirt1 regulates apoptosis and extracellular matrix degradation in resveratrol-treated osteoarthritis chondrocytes via the Wnt/β-catenin signaling pathways. Experimental and therapeutic medicine. vol 14. issue 5. 2020-10-01. PMID:29201214. |
therefore, the present study used 30 clinical oa chondrocyte to examine chondrocyte viability, apoptosis rate and the mrna and protein expression levels of sirt1 and relevant genes implicated in apoptosis, extracellular matrix (ecm) degradation and wnt/β-catenin signaling pathway. |
2020-10-01 |
2023-08-13 |
Not clear |
| Atsunori Tsuchiya, Yuichi Kojima, Shunzo Ikarashi, Satoshi Seino, Yusuke Watanabe, Yuzo Kawata, Shuji Tera. Clinical trials using mesenchymal stem cells in liver diseases and inflammatory bowel diseases. Inflammation and regeneration. vol 37. 2020-10-01. PMID:29259715. |
mscs also produce a large amount of cytokines, chemokines, and growth factors, including exosomes that stimulate angiogenesis, prevent apoptosis, block oxidation reactions, promote remodeling of the extracellular matrix, and induce differentiation of tissue stem cells. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kun Lu, Gang Rui, Fan Liu, Ling Yang, Xiaoling Deng, Songlin Shi, Qifu L. 14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells. Oncology letters. vol 15. issue 1. 2020-10-01. PMID:29285195. |
14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of mg-63 cells. |
2020-10-01 |
2023-08-13 |
human |
| Wencai Sun, Yintai Li, Suizhuan We. miR-4262 regulates chondrocyte viability, apoptosis, autophagy by targeting SIRT1 and activating PI3K/AKT/mTOR signaling pathway in rats with osteoarthritis. Experimental and therapeutic medicine. vol 15. issue 1. 2020-10-01. PMID:29434702. |
furthermore, cell viability, cell apoptosis, cell autophagy and matrix synthesis, as well as the expressions of proteins associated with the phosphoinositide 3-kinase (pi3k)/protein kinase b (akt)/mammalian target of rapamycin (mtor) signaling pathway were detected. |
2020-10-01 |
2023-08-13 |
rat |