| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Feng Liu, Xiangyang Liu, Yue Yang, Zhibo Sun, Shuang Deng, Zhongping Jiang, Wen Li, Fei W. NEAT1/miR-193a-3p/SOX5 axis regulates cartilage matrix degradation in human osteoarthritis. Cell biology international. vol 44. issue 4. 2020-11-19. PMID:31868949. |
the introduction of sox5 abolished the impact of the upregulation of mir-193a-3p on inflammation, apoptosis, and production of extracellular matrix in chondrocytes. |
2020-11-19 |
2023-08-13 |
human |
| Tianyu Xia, Zhentong Shen, Jiarui Cai, Miao Pan, Chao Su. ColXV Aggravates Adipocyte Apoptosis by Facilitating Abnormal Extracellular Matrix Remodeling in Mice. International journal of molecular sciences. vol 21. issue 3. 2020-11-17. PMID:32024006. |
colxv aggravates adipocyte apoptosis by facilitating abnormal extracellular matrix remodeling in mice. |
2020-11-17 |
2023-08-13 |
mouse |
| Wenchong Sun, Jian Wang, Dasheng Cai, Ling Pe. Neuroprotection of the Developing Brain by Dexmedetomidine Is Mediated by Attenuating Single Propofol-induced Hippocampal Apoptosis and Synaptic Plasticity Deficits. Experimental neurobiology. vol 29. issue 5. 2020-11-14. PMID:33154198. |
after a single propofol exposure to p7 rats, dex pretreatment effectively rescued the profound apoptosis seen in hippocampal neurocytes, and strongly reversed the aberrant expression levels of bcl2-like 1 (bcl2l1), matrix metallopeptidase 9 (mmp-9) and cleaved caspase 3 (cc3), and sharply enhanced synaptic plasticity. |
2020-11-14 |
2023-08-13 |
rat |
| Maria Paola Belfiore, Alfonso Reginelli, Nicola Maggialetti, Mattia Carbone, Sabrina Giovine, Antonella Laporta, Fabrizio Urraro, Valerio Nardone, Roberta Grassi, Salvatore Cappabianca, Luca Brunes. Preliminary results in unresectable cholangiocarcinoma treated by CT percutaneous irreversible electroporation: feasibility, safety and efficacy. Medical oncology (Northwood, London, England). vol 37. issue 5. 2020-11-12. PMID:32270353. |
ire is a non-thermal ablation technique that determines cellular apoptosis by electrical impulses without involving extracellular matrix like mw or rf ablation (mwa and rfa). |
2020-11-12 |
2023-08-13 |
Not clear |
| Guillermo A Herrera, Jiamin Teng, Elba A Turbat-Herrera, Chun Zeng, Luis Del Pozo-Yaune. Understanding Mesangial Pathobiology in AL-Amyloidosis and Monoclonal Ig Light Chain Deposition Disease. Kidney international reports. vol 5. issue 11. 2020-11-12. PMID:33163710. |
the interaction with the pathogenic light chain elicits specific cellular processes, which include apoptosis, phenotype transformation, and secretion of extracellular matrix components and metalloproteinases. |
2020-11-12 |
2023-08-13 |
Not clear |
| Sudhir Morla, Ajay Kumar, Sachin Kuma. Newcastle disease virus mediated apoptosis and migration inhibition of human oral cancer cells: A probable role of β-catenin and matrix metalloproteinase-7. Scientific reports. vol 9. issue 1. 2020-11-09. PMID:31350432. |
newcastle disease virus mediated apoptosis and migration inhibition of human oral cancer cells: a probable role of β-catenin and matrix metalloproteinase-7. |
2020-11-09 |
2023-08-13 |
human |
| Richard C Becker, A Phillip Owens, Sakthivel Sadayappa. Tissue-level inflammation and ventricular remodeling in hypertrophic cardiomyopathy. Journal of thrombosis and thrombolysis. vol 49. issue 2. 2020-11-06. PMID:31898271. |
the phenotypic variability observed in hcm is the end-result of many factors, including pre-load, after-load, wall stress and myocardial ischemia stemming from microvascular dysfunction and thrombosis; however, tissue level inflammation to include leukocyte-derived extracellular traps consisting of chromatin and histones, apoptosis, proliferation of matrix proteins and impaired or dysfunctional regulatory pathways contribute as well. |
2020-11-06 |
2023-08-13 |
Not clear |
| Wei Liu, Shuwen Jin, Mi Huang, Yanli Li, ZhiWei Wang, Peng Wang, Xiaolong Zhao, Ping Xia, Jing Fen. Duhuo jisheng decoction suppresses matrix degradation and apoptosis in human nucleus pulposus cells and ameliorates disc degeneration in a rat model. Journal of ethnopharmacology. vol 250. 2020-11-04. PMID:31874213. |
duhuo jisheng decoction suppresses matrix degradation and apoptosis in human nucleus pulposus cells and ameliorates disc degeneration in a rat model. |
2020-11-04 |
2023-08-13 |
human |
| Elena V Tchetina, Kseniya E Glemba, Galina A Markova, Evgeniy A Naryshkin, Elena A Taskina, Maksim A Makarov, Aleksandr M Lil. Development of Postoperative Pain in Patients with End-Stage Knee Osteoarthritis Is Associated with Upregulation of Genes Related to Extracellular Matrix Degradation, Inflammation, and Apoptosis Measured in the Peripheral Blood before Knee Surgery. Life (Basel, Switzerland). vol 10. issue 10. 2020-11-03. PMID:33007930. |
development of postoperative pain in patients with end-stage knee osteoarthritis is associated with upregulation of genes related to extracellular matrix degradation, inflammation, and apoptosis measured in the peripheral blood before knee surgery. |
2020-11-03 |
2023-08-13 |
human |
| Elena V Tchetina, Kseniya E Glemba, Galina A Markova, Evgeniy A Naryshkin, Elena A Taskina, Maksim A Makarov, Aleksandr M Lil. Development of Postoperative Pain in Patients with End-Stage Knee Osteoarthritis Is Associated with Upregulation of Genes Related to Extracellular Matrix Degradation, Inflammation, and Apoptosis Measured in the Peripheral Blood before Knee Surgery. Life (Basel, Switzerland). vol 10. issue 10. 2020-11-03. PMID:33007930. |
high baseline expression of genes associated with extracellular matrix destruction (cathepsins s and k, timp1), inflammation (il-1β, tnfα), and apoptosis (caspase-3) measured in the peripheral blood of patients with end-stage oa before knee arthroplasty might serve as an important biomarker of postoperative pain development. |
2020-11-03 |
2023-08-13 |
human |
| Ava Faridi, Yunxiang Sun, Monika Mortimer, Ritchlynn R Aranha, Aparna Nandakumar, Yuhuan Li, Ibrahim Javed, Aleksandr Kakinen, Qingqing Fan, Anthony W Purcell, Thomas P Davis, Feng Ding, Pouya Faridi, Pu Chun K. Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide. Nano research. vol 12. issue 11. 2020-11-01. PMID:31695851. |
while iapp can activate the nlrp3 inflammasome and modulate cellular autophagy, apoptosis and extracellular matrix metabolism, no data is available concerning intracellular protein expression upon exposure to the polypeptide. |
2020-11-01 |
2023-08-13 |
human |
| Ji-Hua Shi, Pål-Dag Lin. Hallmarks of postoperative liver regeneration: An updated insight on the regulatory mechanisms. Journal of gastroenterology and hepatology. vol 35. issue 6. 2020-10-27. PMID:31782974. |
this review briefly represents a systemic outline of eight hallmarks, including hepatocyte proliferation, contribution of hepatic progenitor cells, inducing angiogenesis, reprogramming of the extracellular matrix, apoptosis and termination of proliferation, inflammation, immune and metabolic regulation, which are set as organizing characteristics of postoperative liver regeneration and future directions of refining treatment targets. |
2020-10-27 |
2023-08-13 |
Not clear |
| Shivam H Patel, Feng Yue, Shannon K Saw, Rachel Foguth, Jason R Cannon, Jonathan H Shannahan, Shihuan Kuang, Arman Sabbaghi, Chad C Carrol. Advanced Glycation End-Products Suppress Mitochondrial Function and Proliferative Capacity of Achilles Tendon-Derived Fibroblasts. Scientific reports. vol 9. issue 1. 2020-10-26. PMID:31471548. |
these impairments were coupled with alterations in mitochondrial dna content and expression of genes associated with extracellular matrix remodeling, mitochondrial energy metabolism, and apoptosis. |
2020-10-26 |
2023-08-13 |
rat |
| Y-J Zhu, D-M Jian. LncRNA PART1 modulates chondrocyte proliferation, apoptosis, and extracellular matrix degradation in osteoarthritis via regulating miR-373-3p/SOX4 axis. European review for medical and pharmacological sciences. vol 23. issue 19. 2020-10-26. PMID:31646607. |
lncrna part1 modulates chondrocyte proliferation, apoptosis, and extracellular matrix degradation in osteoarthritis via regulating mir-373-3p/sox4 axis. |
2020-10-26 |
2023-08-13 |
Not clear |
| Kelsie E Oatmen, Elizabeth Cull, Francis G Spinal. Heart failure as interstitial cancer: emergence of a malignant fibroblast phenotype. Nature reviews. Cardiology. vol 17. issue 8. 2020-10-26. PMID:31686012. |
in animal models, a major factor driving progression from pressure-overload hypertrophy (poh) to hfpef is the activation and proliferation of an abnormal fibroblast phenotype that is resistant to apoptosis, degrades normal stromal matrix and is replaced with a fibrotic matrix structure. |
2020-10-26 |
2023-08-13 |
Not clear |
| Yuan Hu, Xianzhe Dong, Tianyi Zhang, Hongming Ma, Wenshan Yang, Yichen Wang, Ping Liu, Yibang Che. Kai‑Xin‑San suppresses matrix metalloproteinases and myocardial apoptosis in rats with myocardial infarction and depression. Molecular medicine reports. vol 21. issue 1. 2020-10-26. PMID:31746394. |
kai‑xin‑san suppresses matrix metalloproteinases and myocardial apoptosis in rats with myocardial infarction and depression. |
2020-10-26 |
2023-08-13 |
rat |
| Zhongyi Wang, Jinxin Tang, Ying Li, Yu Wang, Yanyang Guo, Qisheng Tu, Jake Chen, Chen Wan. AdipoRon promotes diabetic fracture repair through endochondral ossification-based bone repair by enhancing survival and differentiation of chondrocytes. Experimental cell research. vol 387. issue 2. 2020-10-26. PMID:31838062. |
we found that adiporon could ameliorate cell viability, apoptosis, and reactive oxygen species (ros) production and promote mrna expression of chondrogenic markers and cartilaginous matrix production of atdc5 cells in high glucose medium via activating erk1/2 pathway. |
2020-10-26 |
2023-08-13 |
mouse |
| Akihiro Tsutsumi, Mari Ozaki, Shotaro Chubachi, Hidehiro Irie, Minako Sato, Naofumi Kameyama, Mamoru Sasaki, Makoto Ishii, Ahmed E Hegab, Tomoko Betsuyaku, Koichi Fukunag. Exposure to Cigarette Smoke Enhances the Stemness of Alveolar Type 2 Cells. American journal of respiratory cell and molecular biology. vol 63. issue 3. 2020-10-16. PMID:32338993. |
chronic exposure to cigarette smoke (cs) causes chronic inflammation, oxidative stress, and apoptosis of epithelial cells, which results in destruction of the lung matrix. |
2020-10-16 |
2023-08-13 |
mouse |
| Yanqiu Wang, Yi Yang, Rui Zuo, Junlong Wu, Chao Zhang, Changqing Li, Minghan Liu, Yue Zho. FOXO3 protects nucleus pulposus cells against apoptosis under nutrient deficiency via autophagy. Biochemical and biophysical research communications. vol 524. issue 3. 2020-10-14. PMID:32035615. |
firstly, we found that foxo3 knockdown aggravated nutrient deficiency-induced mitochondrial dysfunction, apoptosis and matrix degradation in npcs. |
2020-10-14 |
2023-08-13 |
human |
| Xiao-Hui Yuan, Ping Zhang, Ting-Ting Yu, Hua-Kun Huang, Lu-Lu Zhang, Chun-Mei Yang, Tao Tan, Sheng-Dong Yang, Xiao-Ji Luo, Jin-Yong Lu. Lycorine inhibits tumor growth of human osteosarcoma cells by blocking Wnt/β-catenin, ERK1/2/MAPK and PI3K/AKT signaling pathway. American journal of translational research. vol 12. issue 9. 2020-10-13. PMID:33042426. |
moreover, we validated that lycorine promoted apoptosis via death receptor pathway and mitochondrial pathway, suppressed migration and invasion by reversing epithelial mesenchymal transition (emt) and suppressing the degradation of extracellular matrix (ecm) |
2020-10-13 |
2023-08-13 |
human |