| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mou Peng, Zijun Wang, Zhonghua Yang, Liu Tao, Qingliang Liu, L U Yi, Xinghuan Wan. Overexpression of short TRPM8 variant α promotes cell migration and invasion, and decreases starvation-induced apoptosis in prostate cancer LNCaP cells. Oncology letters. vol 10. issue 3. 2020-09-29. PMID:26622677. |
overall, the results of the present study indicate that sm8α may be important in the regulation of prostate cancer cell migration and invasion through the activation of matrix metalloproteinase-2, as well as in the regulation of apoptosis through the activation of p-jnk in the mapk signaling pathway. |
2020-09-29 |
2023-08-13 |
Not clear |
| b' Kutay Deniz Atabay, Mehmet Taha Yildiz, Timucin Avsar, Arzu Karabay, T\\xc3\\xbcrker Kili\\xc3\\xa. Knockdown of Pin1 leads to reduced angiogenic potential and tumorigenicity in glioblastoma cells. Oncology letters. vol 10. issue 4. 2020-09-29. PMID:26622856.' |
furthermore, knockdown of pin1 decreased the levels of vascular endothelial growth factor and matrix metallopeptidase 9, and also triggered apoptosis. |
2020-09-29 |
2023-08-13 |
Not clear |
| Jiao Zhang, Ling Guo, Xia Zhou, Fengyun Dong, Liqun Li, Zuowang Cheng, Yinghua Xu, Jiyong Liang, Qi Xie, Ju Li. Dihydroartemisinin induces endothelial cell anoikis through the activation of the JNK signaling pathway. Oncology letters. vol 12. issue 3. 2020-09-29. PMID:27602117. |
during the process of angiogenesis, endothelial cells migrating from existing capillaries may undergo programmed cell death after detaching from the extracellular matrix, a process that is defined as anchorage-dependent apoptosis or anoikis. |
2020-09-29 |
2023-08-13 |
human |
| Eduardo T Santana, Regiane Dos Santos Feliciano, Andrey J Serra, Eduardo Brigidio, Ednei L Antonio, Paulo J F Tucci, Lubov Nathanson, Mariana Morris, José A Silv. Comparative mRNA and MicroRNA Profiling during Acute Myocardial Infarction Induced by Coronary Occlusion and Ablation Radio-Frequency Currents. Frontiers in physiology. vol 7. 2020-09-29. PMID:27932994. |
we analyzed 48 mrnas expressions of nine different signal transduction pathways (cell survival and metabolism signs, matrix extracellular, cell cycle, oxidative stress, apoptosis, calcium signaling, hypertrophy markers, angiogenesis, and inflammation) in rat left ventricle 1 week after mi generated by both coronary occlusion and ab-rf. |
2020-09-29 |
2023-08-13 |
rat |
| Chen Guo, Ling-Feng Xu, Hui-Min Li, Wei Wang, Ji-Hua Guo, Meng-Qi Jia, Rong Jia, Jun Ji. Transcriptomic study of the mechanism of anoikis resistance in head and neck squamous carcinoma. PeerJ. vol 7. 2020-09-29. PMID:31198634. |
normal epithelial cells rapidly undergo apoptosis as soon as they lose contact with the extracellular matrix (ecm), which is termed as anoikis. |
2020-09-29 |
2023-08-13 |
Not clear |
| Robert B Wilson, Wiebke Solass, Rami Archid, Frank-Jürgen Weinreich, Alfred Königsrainer, Marc A Reymon. Resistance to anoikis in transcoelomic shedding: the role of glycolytic enzymes. Pleura and peritoneum. vol 4. issue 1. 2020-09-29. PMID:31198853. |
detachment of cells from the extracellular matrix into the peritoneal cavity initiates a cascade of metabolic alterations, leading usually to cell death by apoptosis, so-called |
2020-09-29 |
2023-08-13 |
Not clear |
| Jialiang Lin, Jiaoxiang Chen, Zengjie Zhang, Tianzhen Xu, Zhenxuan Shao, Xiaobin Wang, Yuanzhe Ding, Naifeng Tian, Haiming Jin, Sunren Sheng, Weiyang Gao, Yan Lin, Xiaolei Zhang, Xiangyang Wan. Luteoloside Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration. Frontiers in pharmacology. vol 10. 2020-09-29. PMID:31427974. |
nuclear factor (erythroid-derived 2)-like 2 (nrf2) is involved in apoptosis, inflammation, and extracellular matrix (ecm) homeostasis. |
2020-09-29 |
2023-08-13 |
rat |
| Dharma Pally, Durjay Pramanik, Ramray Bha. An Interplay Between Reaction-Diffusion and Cell-Matrix Adhesion Regulates Multiscale Invasion in Early Breast Carcinomatosis. Frontiers in physiology. vol 10. 2020-09-29. PMID:31456688. |
the computational model, which comprises adhesion between cancer cells and the matrices, cell proliferation and apoptosis, and matrix remodeling through reaction-diffusion-based morphogen dynamics, is first trained to phenocopy controls run with the experimental model, wherein one or the other matrices have been removed. |
2020-09-29 |
2023-08-13 |
Not clear |
| Yongming Xi, Jinfeng Ma, Yan Che. PTEN promotes intervertebral disc degeneration by regulating nucleus pulposus cell behaviors. Cell biology international. vol 44. issue 2. 2020-09-29. PMID:31663655. |
intervertebral disc degeneration (idd) is induced by multiple factors including increased apoptosis, decreased survival, and reduced extracellular matrix (ecm) synthesis in the nucleus pulposus (np) cells. |
2020-09-29 |
2023-08-13 |
Not clear |
| Hanting Xia, Duanguang Cao, Fo Yang, Wenlong Yang, Wei Li, Pu Liu, Shuhao Wang, Fengyun Yan. Jiawei Yanghe decoction ameliorates cartilage degradation in vitro and vivo via Wnt/β-catenin signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 122. 2020-09-29. PMID:31918279. |
in vitro, jwyhd increased the chondrocyte viability against interleukin (il)-1β-induced chondrocytes apoptosis and preserved glycosaminoglycans in the extracellular matrix. |
2020-09-29 |
2023-08-13 |
rat |
| Hanting Xia, Duanguang Cao, Fo Yang, Wenlong Yang, Wei Li, Pu Liu, Shuhao Wang, Fengyun Yan. Jiawei Yanghe decoction ameliorates cartilage degradation in vitro and vivo via Wnt/β-catenin signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 122. 2020-09-29. PMID:31918279. |
in conclusion, jwyhd possess multiple capabilities including preventing chondrocyte apoptosis, preserving integrity of extracellular matrix and anti-inflammatory effect in the treatment of oa both in vitro and in vivo. |
2020-09-29 |
2023-08-13 |
rat |
| Nana Meng, Zhi Zhao, Chunhe Shi, Leizhou Xi. Inhibiting the Progression of Human Retinoblastoma Cell by Downregulation of MMP-2/MMP-9 Using Short Hairpin RNAs (shRNAs) In Vitro. Journal of ophthalmology. vol 2020. 2020-09-28. PMID:32509341. |
to investigate the effect of downregulated matrix metalloproteinases (mmps) gene on the proliferation, apoptosis, cell cycle, migration, and invasion of human retinoblastoma (rb) cell line in vitro. |
2020-09-28 |
2023-08-13 |
human |
| Bo Fu, Yuhui Zhang, Qingliang Chen, Zhigang Guo, Nan Jian. Antibody microarray analysis of serum inflammatory cytokines in patients with calcific aortic valve disease. Annals of translational medicine. vol 8. issue 12. 2020-09-28. PMID:32647686. |
multiple steps characterize the process: inflammation, cell apoptosis, lipid deposition, renin-angiotensin system activation, extracellular matrix remodeling, and bone formation. |
2020-09-28 |
2023-08-13 |
Not clear |
| Katarzyna Białkowska, Wojciech Marciniak, Magdalena Muszyńska, Piotr Baszuk, Satish Gupta, Katarzyna Jaworska-Bieniek, Grzegorz Sukiennicki, Katarzyna Durda, Tomasz Gromowski, Marcin Lener, Karolina Prajzendanc, Alicja Łukomska, Cezary Cybulski, Tomasz Huzarski, Jacek Gronwald, Tadeusz Dębniak, Jan Lubiński, Anna Jakubowsk. Polymorphisms in Hereditary cancer in clinical practice. vol 18. 2020-09-28. PMID:32765800. |
polymorphisms in matrix metalloproteinases (mmps) and metallothioneins (mts) are zinc-related proteins which are involved in processes crucial for carcinogenesis such as angiogenesis, proliferation and apoptosis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Krisztina Mikulás, Timea Komlódi, Anna Földes, Gergely Sváb, Gergő Horváth, Ádám Miklós Nagy, Attila Ambrus, Szabolcs Gyulai-Gaál, István Gera, Péter Hermann, Gábor Varga, László Trette. Bioenergetic Impairment of Triethylene Glycol Dimethacrylate- (TEGDMA-) Treated Dental Pulp Stem Cells (DPSCs) and Isolated Brain Mitochondria are Amended by Redox Compound Methylene Blue Materials (Basel, Switzerland). vol 13. issue 16. 2020-09-28. PMID:32781723. |
bioenergetic impairment of triethylene glycol dimethacrylate- (tegdma-) treated dental pulp stem cells (dpscs) and isolated brain mitochondria are amended by redox compound methylene blue triethylene glycol dimethacrylate (tegdma) monomers released from resin matrix are toxic to dental pulp cells, induce apoptosis, oxidative stress and decrease viability. |
2020-09-28 |
2023-08-13 |
human |
| Cong Wang, Yuelong Li, Hao Li, Yali Zhang, Zhangguo Ying, Xuye Wang, Tingting Zhang, Wenshu Zhang, Zhichao Fan, Xiaokun Li, Jisheng Ma, Xuebo Pa. Disruption of FGF Signaling Ameliorates Inflammatory Response in Hepatic Stellate Cells. Frontiers in cell and developmental biology. vol 8. 2020-09-28. PMID:32793588. |
however, disruption of fgf signaling with fgfr inhibitors prominently reduced the apoptosis, inflammatory response, nf-κb nuclear translocation, and expression of matrix metalloproteinase-9 (mmp-9) induced by tnfα in hscs. |
2020-09-28 |
2023-08-13 |
human |
| Yi Li. Hydrogen peroxide induces nucleus pulposus cell apoptosis by ATF4/CHOP signaling pathway. Experimental and therapeutic medicine. vol 20. issue 4. 2020-09-28. PMID:32855694. |
oxidative stress induces excessive apoptosis resulting in the reduction of intervertebral disc cells, the consequent reduction of extracellular matrix (ecm) synthesis, and compositional changes, which is the pathological basis for intervertebral disc degeneration (ivdd). |
2020-09-28 |
2023-08-13 |
Not clear |
| Aixin Zhao, Yunfang Qi, Kun Li. CLDN3 expression and function in pregnancy-induced hypertension. Experimental and therapeutic medicine. vol 20. issue 4. 2020-09-28. PMID:32855729. |
cell counting kit-8 (cck-8) assay, flow cytometry, transwell chamber assays, confocal laser scanning microscopy and western blot analysis were performed to detect cell proliferation, invasion, migration and apoptosis, in addition to matrix metalloproteinase (mmp) expression and erk1/2 phosphorylation. |
2020-09-28 |
2023-08-13 |
human |
| Eric Guberman, Hikmet Sherief, Erzsébet Ravasz Rega. Boolean model of anchorage dependence and contact inhibition points to coordinated inhibition but semi-independent induction of proliferation and migration. Computational and structural biotechnology journal. vol 18. 2020-09-28. PMID:32913583. |
here we propose a boolean regulatory network model that synthesizes mechanosensitive signaling that links anchorage to a matrix of varying stiffness and cell density sensing to contact inhibition, proliferation, migration, and apoptosis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Xiao-Juan Chen, Jian-Guo Zhang, Lan W. Plumbagin inhibits neuronal apoptosis, intimal hyperplasia and also suppresses TNF-α/NF-κB pathway induced inflammation and matrix metalloproteinase-2/9 expression in rat cerebral ischemia. Saudi journal of biological sciences. vol 25. issue 6. 2020-09-28. PMID:30174499. |
plumbagin inhibits neuronal apoptosis, intimal hyperplasia and also suppresses tnf-α/nf-κb pathway induced inflammation and matrix metalloproteinase-2/9 expression in rat cerebral ischemia. |
2020-09-28 |
2023-08-13 |
rat |