| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elena V Tchetina, Kseniya E Glemba, Galina A Markova, Evgeniy A Naryshkin, Elena A Taskina, Maksim A Makarov, Aleksandr M Lil. Development of Postoperative Pain in Patients with End-Stage Knee Osteoarthritis Is Associated with Upregulation of Genes Related to Extracellular Matrix Degradation, Inflammation, and Apoptosis Measured in the Peripheral Blood before Knee Surgery. Life (Basel, Switzerland). vol 10. issue 10. 2020-11-03. PMID:33007930. |
development of postoperative pain in patients with end-stage knee osteoarthritis is associated with upregulation of genes related to extracellular matrix degradation, inflammation, and apoptosis measured in the peripheral blood before knee surgery. |
2020-11-03 |
2023-08-13 |
human |
| Elena V Tchetina, Kseniya E Glemba, Galina A Markova, Evgeniy A Naryshkin, Elena A Taskina, Maksim A Makarov, Aleksandr M Lil. Development of Postoperative Pain in Patients with End-Stage Knee Osteoarthritis Is Associated with Upregulation of Genes Related to Extracellular Matrix Degradation, Inflammation, and Apoptosis Measured in the Peripheral Blood before Knee Surgery. Life (Basel, Switzerland). vol 10. issue 10. 2020-11-03. PMID:33007930. |
high baseline expression of genes associated with extracellular matrix destruction (cathepsins s and k, timp1), inflammation (il-1β, tnfα), and apoptosis (caspase-3) measured in the peripheral blood of patients with end-stage oa before knee arthroplasty might serve as an important biomarker of postoperative pain development. |
2020-11-03 |
2023-08-13 |
human |
| Ava Faridi, Yunxiang Sun, Monika Mortimer, Ritchlynn R Aranha, Aparna Nandakumar, Yuhuan Li, Ibrahim Javed, Aleksandr Kakinen, Qingqing Fan, Anthony W Purcell, Thomas P Davis, Feng Ding, Pouya Faridi, Pu Chun K. Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide. Nano research. vol 12. issue 11. 2020-11-01. PMID:31695851. |
while iapp can activate the nlrp3 inflammasome and modulate cellular autophagy, apoptosis and extracellular matrix metabolism, no data is available concerning intracellular protein expression upon exposure to the polypeptide. |
2020-11-01 |
2023-08-13 |
human |
| Ji-Hua Shi, Pål-Dag Lin. Hallmarks of postoperative liver regeneration: An updated insight on the regulatory mechanisms. Journal of gastroenterology and hepatology. vol 35. issue 6. 2020-10-27. PMID:31782974. |
this review briefly represents a systemic outline of eight hallmarks, including hepatocyte proliferation, contribution of hepatic progenitor cells, inducing angiogenesis, reprogramming of the extracellular matrix, apoptosis and termination of proliferation, inflammation, immune and metabolic regulation, which are set as organizing characteristics of postoperative liver regeneration and future directions of refining treatment targets. |
2020-10-27 |
2023-08-13 |
Not clear |
| Shivam H Patel, Feng Yue, Shannon K Saw, Rachel Foguth, Jason R Cannon, Jonathan H Shannahan, Shihuan Kuang, Arman Sabbaghi, Chad C Carrol. Advanced Glycation End-Products Suppress Mitochondrial Function and Proliferative Capacity of Achilles Tendon-Derived Fibroblasts. Scientific reports. vol 9. issue 1. 2020-10-26. PMID:31471548. |
these impairments were coupled with alterations in mitochondrial dna content and expression of genes associated with extracellular matrix remodeling, mitochondrial energy metabolism, and apoptosis. |
2020-10-26 |
2023-08-13 |
rat |
| Y-J Zhu, D-M Jian. LncRNA PART1 modulates chondrocyte proliferation, apoptosis, and extracellular matrix degradation in osteoarthritis via regulating miR-373-3p/SOX4 axis. European review for medical and pharmacological sciences. vol 23. issue 19. 2020-10-26. PMID:31646607. |
lncrna part1 modulates chondrocyte proliferation, apoptosis, and extracellular matrix degradation in osteoarthritis via regulating mir-373-3p/sox4 axis. |
2020-10-26 |
2023-08-13 |
Not clear |
| Kelsie E Oatmen, Elizabeth Cull, Francis G Spinal. Heart failure as interstitial cancer: emergence of a malignant fibroblast phenotype. Nature reviews. Cardiology. vol 17. issue 8. 2020-10-26. PMID:31686012. |
in animal models, a major factor driving progression from pressure-overload hypertrophy (poh) to hfpef is the activation and proliferation of an abnormal fibroblast phenotype that is resistant to apoptosis, degrades normal stromal matrix and is replaced with a fibrotic matrix structure. |
2020-10-26 |
2023-08-13 |
Not clear |
| Yuan Hu, Xianzhe Dong, Tianyi Zhang, Hongming Ma, Wenshan Yang, Yichen Wang, Ping Liu, Yibang Che. Kai‑Xin‑San suppresses matrix metalloproteinases and myocardial apoptosis in rats with myocardial infarction and depression. Molecular medicine reports. vol 21. issue 1. 2020-10-26. PMID:31746394. |
kai‑xin‑san suppresses matrix metalloproteinases and myocardial apoptosis in rats with myocardial infarction and depression. |
2020-10-26 |
2023-08-13 |
rat |
| Zhongyi Wang, Jinxin Tang, Ying Li, Yu Wang, Yanyang Guo, Qisheng Tu, Jake Chen, Chen Wan. AdipoRon promotes diabetic fracture repair through endochondral ossification-based bone repair by enhancing survival and differentiation of chondrocytes. Experimental cell research. vol 387. issue 2. 2020-10-26. PMID:31838062. |
we found that adiporon could ameliorate cell viability, apoptosis, and reactive oxygen species (ros) production and promote mrna expression of chondrogenic markers and cartilaginous matrix production of atdc5 cells in high glucose medium via activating erk1/2 pathway. |
2020-10-26 |
2023-08-13 |
mouse |
| Akihiro Tsutsumi, Mari Ozaki, Shotaro Chubachi, Hidehiro Irie, Minako Sato, Naofumi Kameyama, Mamoru Sasaki, Makoto Ishii, Ahmed E Hegab, Tomoko Betsuyaku, Koichi Fukunag. Exposure to Cigarette Smoke Enhances the Stemness of Alveolar Type 2 Cells. American journal of respiratory cell and molecular biology. vol 63. issue 3. 2020-10-16. PMID:32338993. |
chronic exposure to cigarette smoke (cs) causes chronic inflammation, oxidative stress, and apoptosis of epithelial cells, which results in destruction of the lung matrix. |
2020-10-16 |
2023-08-13 |
mouse |
| Yanqiu Wang, Yi Yang, Rui Zuo, Junlong Wu, Chao Zhang, Changqing Li, Minghan Liu, Yue Zho. FOXO3 protects nucleus pulposus cells against apoptosis under nutrient deficiency via autophagy. Biochemical and biophysical research communications. vol 524. issue 3. 2020-10-14. PMID:32035615. |
firstly, we found that foxo3 knockdown aggravated nutrient deficiency-induced mitochondrial dysfunction, apoptosis and matrix degradation in npcs. |
2020-10-14 |
2023-08-13 |
human |
| Xiao-Hui Yuan, Ping Zhang, Ting-Ting Yu, Hua-Kun Huang, Lu-Lu Zhang, Chun-Mei Yang, Tao Tan, Sheng-Dong Yang, Xiao-Ji Luo, Jin-Yong Lu. Lycorine inhibits tumor growth of human osteosarcoma cells by blocking Wnt/β-catenin, ERK1/2/MAPK and PI3K/AKT signaling pathway. American journal of translational research. vol 12. issue 9. 2020-10-13. PMID:33042426. |
moreover, we validated that lycorine promoted apoptosis via death receptor pathway and mitochondrial pathway, suppressed migration and invasion by reversing epithelial mesenchymal transition (emt) and suppressing the degradation of extracellular matrix (ecm) |
2020-10-13 |
2023-08-13 |
human |
| Lei Wu, Kan Zhang, Liping Sun, Jie Bai, Mazhong Zhang, Jijian Zhen. Laminin degradation by matrix metalloproteinase 9 promotes ketamine-induced neuronal apoptosis in the early developing rat retina. CNS neuroscience & therapeutics. 2020-10-10. PMID:32562453. |
laminin degradation by matrix metalloproteinase 9 promotes ketamine-induced neuronal apoptosis in the early developing rat retina. |
2020-10-10 |
2023-08-13 |
rat |
| ShaoWen Cheng, Lei Peng, BaiChao Xu, WenSheng Chen, YangPing Chen, YunTao G. Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-10-07. PMID:31927559. |
protective effects of hydrogen-rich water against cartilage damage in a rat model of osteoarthritis by inhibiting oxidative stress, matrix catabolism, and apoptosis. |
2020-10-07 |
2023-08-13 |
rat |
| Xi Sun, Lijun Gan, Nan Li, Shuyi Sun, Na L. Tabersonine ameliorates osteoblast apoptosis in rats with dexamethasone-induced osteoporosis by regulating the Nrf2/ROS/Bax signalling pathway. AMB Express. vol 10. issue 1. 2020-10-01. PMID:32915329. |
tab increased cell viability and alp activity, and reduced the mitochondrial superoxide, reactive oxygen species and matrix metalloproteinase levels and osteoblast apoptosis. |
2020-10-01 |
2023-08-13 |
rat |
| Yasuyoshi Miyata, Kensuke Mitsunari, Asai Akihiro, Shin-Ichi Watanabe, Yasushi Mochizuki, Hideki Saka. Smoking-induced changes in cancer-related factors in patients with upper tract urothelial cancer. Molecular and clinical oncology. vol 3. issue 2. 2020-10-01. PMID:25798255. |
we investigated the associations between smoking status and cancer-related factors, including cancer cell proliferation, apoptosis, angiogenesis, lymphangiogenesis and expression of vascular endothelial growth factor-a and -c, matrix metalloproteinase (mmp)-2 and -9, cyclooxygenase (cox)-2 and urokinase-type plasminogen activator, in patients with utuc. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yunhua Tang, Xiangyang Zhang, Fan Qi, Mingfeng Chen, Yuan Li, Longfei Liu, Wei He, Zhuo Li, Xiongbing Z. Afatinib inhibits proliferation and invasion and promotes apoptosis of the T24 bladder cancer cell line. Experimental and therapeutic medicine. vol 9. issue 5. 2020-10-01. PMID:26136904. |
mtt assay was used to estimate the proliferation of the t24 cells; flow cytometric analysis was used to estimate the effect of afatinib on t24 cell apoptosis; cell invasion ability was assessed by a transwell invasion assay; and western blot analysis was used to detect the expression of bcl-2, bax, akt, extracellular-signal-regulated kinase (erk)1/2, matrix metalloproteinase (mmp)-2 and mmp-9. |
2020-10-01 |
2023-08-13 |
human |
| Antonietta Restuccia, Ye F Tian, Joel H Collier, Gregory A Hudall. Self-assembled glycopeptide nanofibers as modulators of galectin-1 bioactivity. Cellular and molecular bioengineering. vol 8. issue 3. 2020-10-01. PMID:26495044. |
galectin bioactivity is mediated by specific non-covalent interactions with cell-surface and extracellular matrix (ecm) glycoproteins, which can enhance or inhibit signaling events that influence various cellular behaviors, including adhesion, proliferation, differentiation, and apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Shao-Qing Chen, Jian-Ping Lin, Qi-Kai Zheng, Shui-Jin Chen, Ming Li, Xian-Zhao Lin, Shi-Zhong Wan. Protective effects of paeoniflorin against FasL-induced apoptosis of intervertebral disc annulus fibrosus cells via Fas-FasL signalling pathway. Experimental and therapeutic medicine. vol 10. issue 6. 2020-10-01. PMID:26668640. |
in the present study, we demonstrate that the degeneration of intervertebral discs is caused by ageing and apoptosis of matrix cells. |
2020-10-01 |
2023-08-13 |
rat |
| Zhirong Wang, Genlin Wang, Xuesong Zhu, Dechun Geng, Huilin Yan. Interleukin-2 is upregulated in patients with a prolapsed lumbar intervertebral disc and modulates cell proliferation, apoptosis and extracellular matrix metabolism of human nucleus pulposus cells. Experimental and therapeutic medicine. vol 10. issue 6. 2020-10-01. PMID:26668654. |
interleukin-2 is upregulated in patients with a prolapsed lumbar intervertebral disc and modulates cell proliferation, apoptosis and extracellular matrix metabolism of human nucleus pulposus cells. |
2020-10-01 |
2023-08-13 |
human |