| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Steven E Wilson, Andre A M Torricelli, Gustavo K Marin. Corneal epithelial basement membrane: Structure, function and regeneration. Experimental eye research. vol 194. 2020-12-15. PMID:32179076. |
transparency is subsequently restored if the ebm is fully regenerated, myofibroblasts are deprived of tgf-β and undergo apoptosis, and keratocytes reoccupy the anterior stroma and reabsorb the disordered extracellular matrix. |
2020-12-15 |
2023-08-13 |
Not clear |
| Laura M Marquardt, Vanessa M Doulames, Alice T Wang, Karen Dubbin, Riley A Suhar, Michael J Kratochvil, Zachary A Medress, Giles W Plant, Sarah C Heilshor. Designer, injectable gels to prevent transplanted Schwann cell loss during spinal cord injury therapy. Science advances. vol 6. issue 14. 2020-12-15. PMID:32270042. |
we present a materials-based strategy that addresses three common causes of transplanted cell death: (i) membrane damage during injection, (ii) cell leakage from the injection site, and (iii) apoptosis due to loss of endogenous matrix. |
2020-12-15 |
2023-08-13 |
Not clear |
| Manisha Agarwal, Mitchell Goheen, Shijing Jia, Song Ling, Eric S White, Kevin K Ki. Type I Collagen Signaling Regulates Opposing Fibrotic Pathways through α American journal of respiratory cell and molecular biology. vol 63. issue 5. 2020-12-09. PMID:32692932. |
fibroblasts cultured on type i collagen or fibrotic decellularized lung matrix had augmented activation in response to tgf-β, whereas aecs on cultured on type i collagen or fibrotic lung matrix were more resistant to tgf-β-induced apoptosis. |
2020-12-09 |
2023-08-13 |
Not clear |
| Chanchal Garg, Hitender Sharma, Munish Gar. Skin photo-protection with phytochemicals against photo-oxidative stress, photo-carcinogenesis, signal transduction pathways and extracellular matrix remodeling-An overview. Ageing research reviews. vol 62. 2020-12-04. PMID:32721499. |
the contribution of phytochemicals to the downregulation of expression of oxidative-stress sensitive transcription factors (nrf2, nf-kb, ap-1 and p53) and protein kinases (msk, erk, jnk, p38 mapk, p90rsk2 and camks) involved in inflammation, apoptosis, immune suppression, extracellular matrix remodelling, senescence, photo ageing and photo-carcinogenesis, is also discussed. |
2020-12-04 |
2023-08-13 |
Not clear |
| Zhiyong Shu, Xiaogang Miao, Tainhua Tang, Peng Zhan, Langqing Zeng, Yuwen Jian. The GSK‑3β/β‑catenin signaling pathway is involved in HMGB1‑induced chondrocyte apoptosis and cartilage matrix degradation. International journal of molecular medicine. vol 45. issue 3. 2020-11-30. PMID:31922219. |
the gsk‑3β/β‑catenin signaling pathway is involved in hmgb1‑induced chondrocyte apoptosis and cartilage matrix degradation. |
2020-11-30 |
2023-08-13 |
Not clear |
| JinYoung Park, Ji-Hyun Lee, Youngbin Lee, Donghoon Lee, Moon Jong Kim, Kwang-Min Cho. Necrotic cell death induces melanotic mass formation in Drosophila. Biochemical and biophysical research communications. vol 526. issue 4. 2020-11-25. PMID:32312516. |
upon the loss of cell matrix attachment, endocycling polyploid tissues of the drosophila larva undergo autophagy instead of apoptosis; we employed this system as a model to examine cell death modalities and immunity. |
2020-11-25 |
2023-08-13 |
drosophila_melanogaster |
| Jing Zhao, Yiran Hou, Chun Yin, Jing Hu, Tian Gao, Xiaojun Huang, Xiaohong Zhang, Jinliang Xing, Jiaze An, Shaogui Wan, Jibin L. Upregulation of histamine receptor H1 promotes tumor progression and contributes to poor prognosis in hepatocellular carcinoma. Oncogene. vol 39. issue 8. 2020-11-24. PMID:31740780. |
functional experiments revealed that h1hr promoted both the growth and metastasis of hcc cells by inducing cell cycle progression, formation of lamellipodia, production of matrix metalloproteinase 2, and suppression of cell apoptosis. |
2020-11-24 |
2023-08-13 |
mouse |
| Yunfang Cai, Wen Zhang, Runze Zhang, Xiaoying Cui, Jun Fan. Combined Use of Three Machine Learning Modeling Methods to Develop a Ten-Gene Signature for the Diagnosis of Ventilator-Associated Pneumonia. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-11-24. PMID:32031163. |
upregulated genes included matrix metallopeptidase 8 (mmp8), arginase 1 (arg1), haptoglobin (hp), interleukin 18 receptor 1 (il18r1), and nlr family apoptosis inhibitory protein (naip). |
2020-11-24 |
2023-08-13 |
Not clear |
| Weitian Li, Qiyu Tang, Na Dai, Weikuan Feng, Changqing Xie, Guofu Cheng, Xiaoli Liu, Wanpo Zhang, Xueying Hu, Changqin G. Receptor-interacting serine/threonine kinase 1- and 3-dependent inflammation induced in lungs of chicken infected with Pasteurella multocida. Scientific reports. vol 10. issue 1. 2020-11-24. PMID:32286320. |
the inflammatory factors hmgb1 and il-6, intercellular matrix mmp, the cell apoptosis-associated caspase-3 and necrotic apoptosis signal molecules ripk1 and ripk3 were widely expressed in the lungs of group q and were significantly different compared with those of 1g1 group and uninfected group (p < 0.05). |
2020-11-24 |
2023-08-13 |
chicken |
| Jing Chen, Ye Yang, Jingjing Wu, Xue Rui, Wei Wang, Rongrong Ren, Qingqing Zhang, Qingqing Chen, Dengke Yi. Spatiotemporal variations of contact stress between liquid-crystal films and fibroblasts Guide cell fate and skin regeneration. Colloids and surfaces. B, Biointerfaces. vol 188. 2020-11-23. PMID:31881410. |
but the gradually weakening cellular contact stress, induced by the decreasing of liquid crystal domains of matrix polymer during degradation, triggers the apoptosis of fibroblasts and myofibroblasts, resulting in non-excessive collagen accumulation. |
2020-11-23 |
2023-08-13 |
Not clear |
| Jun Shirakawa, Yasuo Terauch. Newer perspective on the coupling between glucose-mediated signaling and β-cell functionality. Endocrine journal. vol 67. issue 1. 2020-11-19. PMID:31694991. |
glucokinase-mediated glucose metabolism (1) suppresses endoplasmic reticulum (er) stress-induced β-cell apoptosis via inducing insulin receptor substrate-2 (irs-2) expression and expression of er stress-related molecules, (2) promotes adaptive β-cell proliferation through activation of the forkhead box m1 (foxm1)/polo-like kinase-1 (plk1)/centromere protein-a (cenp-a) pathway, (3) induces islet inflammation by promoting interaction of islet-derived s100 calcium-binding protein a8 (s100a8) with macrophages, (4) induces the expression of fibulin-5 (fbln5), an extracellular matrix protein to regulate β-cell functions, and (5) activates other unknown pathways. |
2020-11-19 |
2023-08-13 |
mouse |
| Feng Liu, Xiangyang Liu, Yue Yang, Zhibo Sun, Shuang Deng, Zhongping Jiang, Wen Li, Fei W. NEAT1/miR-193a-3p/SOX5 axis regulates cartilage matrix degradation in human osteoarthritis. Cell biology international. vol 44. issue 4. 2020-11-19. PMID:31868949. |
silencing of mir-193a-3p reversed the neat1 knockdown-mediated effect on the inflammation, apoptosis, and production of the extracellular matrix. |
2020-11-19 |
2023-08-13 |
human |
| Feng Liu, Xiangyang Liu, Yue Yang, Zhibo Sun, Shuang Deng, Zhongping Jiang, Wen Li, Fei W. NEAT1/miR-193a-3p/SOX5 axis regulates cartilage matrix degradation in human osteoarthritis. Cell biology international. vol 44. issue 4. 2020-11-19. PMID:31868949. |
the introduction of sox5 abolished the impact of the upregulation of mir-193a-3p on inflammation, apoptosis, and production of extracellular matrix in chondrocytes. |
2020-11-19 |
2023-08-13 |
human |
| Tianyu Xia, Zhentong Shen, Jiarui Cai, Miao Pan, Chao Su. ColXV Aggravates Adipocyte Apoptosis by Facilitating Abnormal Extracellular Matrix Remodeling in Mice. International journal of molecular sciences. vol 21. issue 3. 2020-11-17. PMID:32024006. |
colxv aggravates adipocyte apoptosis by facilitating abnormal extracellular matrix remodeling in mice. |
2020-11-17 |
2023-08-13 |
mouse |
| Wenchong Sun, Jian Wang, Dasheng Cai, Ling Pe. Neuroprotection of the Developing Brain by Dexmedetomidine Is Mediated by Attenuating Single Propofol-induced Hippocampal Apoptosis and Synaptic Plasticity Deficits. Experimental neurobiology. vol 29. issue 5. 2020-11-14. PMID:33154198. |
after a single propofol exposure to p7 rats, dex pretreatment effectively rescued the profound apoptosis seen in hippocampal neurocytes, and strongly reversed the aberrant expression levels of bcl2-like 1 (bcl2l1), matrix metallopeptidase 9 (mmp-9) and cleaved caspase 3 (cc3), and sharply enhanced synaptic plasticity. |
2020-11-14 |
2023-08-13 |
rat |
| Guillermo A Herrera, Jiamin Teng, Elba A Turbat-Herrera, Chun Zeng, Luis Del Pozo-Yaune. Understanding Mesangial Pathobiology in AL-Amyloidosis and Monoclonal Ig Light Chain Deposition Disease. Kidney international reports. vol 5. issue 11. 2020-11-12. PMID:33163710. |
the interaction with the pathogenic light chain elicits specific cellular processes, which include apoptosis, phenotype transformation, and secretion of extracellular matrix components and metalloproteinases. |
2020-11-12 |
2023-08-13 |
Not clear |
| Maria Paola Belfiore, Alfonso Reginelli, Nicola Maggialetti, Mattia Carbone, Sabrina Giovine, Antonella Laporta, Fabrizio Urraro, Valerio Nardone, Roberta Grassi, Salvatore Cappabianca, Luca Brunes. Preliminary results in unresectable cholangiocarcinoma treated by CT percutaneous irreversible electroporation: feasibility, safety and efficacy. Medical oncology (Northwood, London, England). vol 37. issue 5. 2020-11-12. PMID:32270353. |
ire is a non-thermal ablation technique that determines cellular apoptosis by electrical impulses without involving extracellular matrix like mw or rf ablation (mwa and rfa). |
2020-11-12 |
2023-08-13 |
Not clear |
| Sudhir Morla, Ajay Kumar, Sachin Kuma. Newcastle disease virus mediated apoptosis and migration inhibition of human oral cancer cells: A probable role of β-catenin and matrix metalloproteinase-7. Scientific reports. vol 9. issue 1. 2020-11-09. PMID:31350432. |
newcastle disease virus mediated apoptosis and migration inhibition of human oral cancer cells: a probable role of β-catenin and matrix metalloproteinase-7. |
2020-11-09 |
2023-08-13 |
human |
| Richard C Becker, A Phillip Owens, Sakthivel Sadayappa. Tissue-level inflammation and ventricular remodeling in hypertrophic cardiomyopathy. Journal of thrombosis and thrombolysis. vol 49. issue 2. 2020-11-06. PMID:31898271. |
the phenotypic variability observed in hcm is the end-result of many factors, including pre-load, after-load, wall stress and myocardial ischemia stemming from microvascular dysfunction and thrombosis; however, tissue level inflammation to include leukocyte-derived extracellular traps consisting of chromatin and histones, apoptosis, proliferation of matrix proteins and impaired or dysfunctional regulatory pathways contribute as well. |
2020-11-06 |
2023-08-13 |
Not clear |
| Wei Liu, Shuwen Jin, Mi Huang, Yanli Li, ZhiWei Wang, Peng Wang, Xiaolong Zhao, Ping Xia, Jing Fen. Duhuo jisheng decoction suppresses matrix degradation and apoptosis in human nucleus pulposus cells and ameliorates disc degeneration in a rat model. Journal of ethnopharmacology. vol 250. 2020-11-04. PMID:31874213. |
duhuo jisheng decoction suppresses matrix degradation and apoptosis in human nucleus pulposus cells and ameliorates disc degeneration in a rat model. |
2020-11-04 |
2023-08-13 |
human |