| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guangming Ren, Liming Xu, Jingzhuang Zhao, Yizhi Shao, Tongyan Lu, Qiya Zhan. Comparative transcriptome analysis of long non coding RNA (lncRNA) in RTG-2 cells infected by infectious hematopoietic necrosis virus. Fish & shellfish immunology. vol 120. 2021-12-11. PMID:34890776. |
further analysis found that some de-lncrnas might participate in the regulation of extracellular matrix metabolism, apoptosis, lipid synthesis, autophagy, and immune responses referring to the functions of their target genes. |
2021-12-11 |
2023-08-13 |
Not clear |
| Paloma Ruiz-Blázquez, Valeria Pistorio, María Fernández-Fernández, Anna Mole. The multifaceted role of cathepsins in liver disease. Journal of hepatology. vol 75. issue 5. 2021-12-10. PMID:34242696. |
they can operate alone or as part of signalling cascades and regulatory circuits, playing important roles in apoptosis, extracellular matrix remodelling, hepatic stellate cell activation, autophagy and metastasis, contributing to the initiation, development and progression of liver disease. |
2021-12-10 |
2023-08-13 |
Not clear |
| Sarah J Richardson, Alberto Puglies. 100 YEARS OF INSULIN: Pancreas pathology in type 1 diabetes: an evolving story. The Journal of endocrinology. vol 252. issue 2. 2021-12-10. PMID:34755679. |
additionally, there are changes affecting extracellular matrix components, evidence of viral infections, inflammation, and er stress, which could contribute to beta-cell dysfunction and the stimulation of apoptosis and autoimmunity. |
2021-12-10 |
2023-08-13 |
Not clear |
| Sadia Perveen, Daniela Rossin, Emanuela Vitale, Rachele Rosso, Roberto Vanni, Caterina Cristallini, Raffaella Rastaldo, Claudia Giachin. Therapeutic Acellular Scaffolds for Limiting Left Ventricular Remodelling-Current Status and Future Directions. International journal of molecular sciences. vol 22. issue 23. 2021-12-10. PMID:34884856. |
following mi, the hypoxic microenvironment triggers apoptosis, disrupts the extracellular matrix and forms a non-functional scar that leads towards adverse left ventricular (lv) remodelling. |
2021-12-10 |
2023-08-13 |
Not clear |
| Xiaohe Li, Hailong Li, Shanshan Zhang, Ruotong Zhang, Jinhe Li, Yiying Wei, Cheng Yang, Fubo Zhang, Honggang Zho. Protective effect of Idelalisib on carbon tetrachloride-induced liver fibrosis via microRNA-124-3P/phosphatidylinositol-3-hydroxykinase signalling pathway. Journal of cellular and molecular medicine. vol 25. issue 24. 2021-12-07. PMID:34747105. |
inhibition of pi3k/akt signalling pathway can reduce the deposition of extracellular matrix, inhibit the proliferation of hepatic stellate cells (hscs), and promote its apoptosis to achieve the purpose of therapy. |
2021-12-07 |
2023-08-13 |
Not clear |
| Shuai Huang, Kai Luo, Li Jiang, Xu-Dong Zhang, Ying-Hao Lv, Ren-Feng L. PCBP1 regulates the transcription and alternative splicing of metastasis‑related genes and pathways in hepatocellular carcinoma. Scientific reports. vol 11. issue 1. 2021-12-07. PMID:34857818. |
we obtained and analysed pcbp1-knockdown rna-seq data and eclip-seq data of pcbp1 in hepg2 cells and found that pcbp1 widely regulates the alternative splicing and expression of genes enriched in cancer-related pathways, including extracellular matrix, cell adhesion, small molecule metabolic process and apoptosis. |
2021-12-07 |
2023-08-13 |
human |
| Manipa Saha, Neha Deshpande, Abhinav Dubey, Debnath Pal, Hanudatta S Atreya, Annapoorni Rangaraja. Sustained AMPK Activation and Proline Metabolism Play Critical Roles in the Survival of Matrix-Deprived Transformed Cells. Frontiers in cell and developmental biology. vol 9. 2021-12-07. PMID:34869367. |
attachment to the matrix is critical for the survival of adherent cells, whereas detachment triggers death by apoptosis. |
2021-12-07 |
2023-08-13 |
Not clear |
| Qian Wang, Zhaoyang Chen, Xiaoping Peng, Zeqi Zheng, Aiping Le, Junjie Guo, Leilei Ma, Hongtao Shi, Kang Yao, Shuning Zhang, Zhenzhong Zheng, Jianbing Zh. Neuraminidase 1 Exacerbating Aortic Dissection by Governing a Pro-Inflammatory Program in Macrophages. Frontiers in cardiovascular medicine. vol 8. 2021-12-07. PMID:34869700. |
improved outcomes in neu1 cko mice subjected to bapn treatment were associated with the ameliorated vascular inflammation, lowered apoptosis, decreased reactive oxygen species production, mitigated extracellular matrix degradation, and improved m2 macrophage polarization. |
2021-12-07 |
2023-08-13 |
mouse |
| Zhaoping Che, Jie Xueqin, Zongyu Zhan. LncRNA OIP5-AS1 accelerates intervertebral disc degeneration by targeting miR-25-3p. Bioengineered. vol 12. issue 2. 2021-12-07. PMID:34872452. |
after oip5-as1 was silenced, cell proliferation was boosted whereas both apoptosis and extracellular matrix (ecm) degradation were restrained. |
2021-12-07 |
2023-08-13 |
Not clear |
| Greg J Beite. Organ remodeling: The molecular choreography of a dance of destruction. Current biology : CB. vol 31. issue 23. 2021-12-07. PMID:34875239. |
a new study reveals that the drosophila tracheal system is disassembled during pupation via ecdysone-dependent remodeling of the extracellular matrix, which then signals through the hippo-yorkie/yap network to induce apoptosis. |
2021-12-07 |
2023-08-13 |
drosophila_melanogaster |
| Viktor Zaykov, Brahim Chaqou. The CCN2/CTGF interactome: an approach to understanding the versatility of CCN2/CTGF molecular activities. Journal of cell communication and signaling. vol 15. issue 4. 2021-12-06. PMID:34613590. |
cellular communication network 2 (ccn2), also known as connective tissue growth factor (ctgf) regulates diverse cellular processes, some at odds with others, including adhesion, proliferation, apoptosis, and extracellular matrix (ecm) protein synthesis. |
2021-12-06 |
2023-08-13 |
Not clear |
| Chun-Min Su, Song-Shei Lin, Hsiao-Chia Wang, Fei-Ting Hsu, Jing Gung Chung, Li-Cho Hs. The inhibitory effect and mechanism of quetiapine on tumor progression in hepatocellular carcinoma in vivo. Environmental toxicology. vol 37. issue 1. 2021-12-06. PMID:34626444. |
extracellular signal-regulated kinases (erks) and nuclear factor-κb (nf-κb) mediated downstream proteins, such as myeloid leukemia cell differentiation protein (mcl-1), cellular flice-inhibitory protein (c-flip), x-linked inhibitor of apoptosis protein (xiap), cyclin-d1, matrix metallopeptidase 9 (mmp-9), vascular endothelial growth factor-a (vegf-a) and indoleamine 2,3-dioxygenase (ido) which involved in proliferation, survival, angiogenesis, invasion and anti-tumor immunity were all decreased by quetiapine. |
2021-12-06 |
2023-08-13 |
Not clear |
| b' Aleksandra Augu\\xc5\\x9bciak-Duma, Marta Lesiak, Karolina St\\xc4\\x99pie\\xc5\\x84, Ewa Gutmajster, Aleksander L Siero\\xc5\\x8. mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report. Acta biochimica Polonica. vol 68. issue 4. 2021-12-06. PMID:34669362.' |
abdominal aortic aneurysm is a process involving the disruption and reconstruction of the extracellular matrix and the apoptosis of smooth muscle cells under the strong influence of the immune system. |
2021-12-06 |
2023-08-13 |
human |
| Ellen E Quillen, Jaydee Foster, Anne Sheldrake, Maggie Stainback, Jeremy Glenn, Laura A Cox, Todd L Bredbenne. Circulating miRNAs associated with bone mineral density in healthy adult baboons. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2021-12-04. PMID:34799865. |
we suggest that these mirnas are involved in the regulation of cellular proliferation, apoptosis, and protein composition in the extracellular matrix throughout life; and age-related dysregulation of these systems may lead to disease. |
2021-12-04 |
2023-08-13 |
human |
| Hua Guan, Xiaofeng Yang, Tao Shi, Yongjian Zhang, Aoqi Xiang, Yongxin L. CTRP9 Mitigates the Progression of Arteriovenous Shunt-Induced Pulmonary Artery Hypertension in Rats. Cardiovascular therapeutics. vol 2021. 2021-12-04. PMID:34858521. |
ctrp9 attenuated the pulmonary vascular remodeling in the shunt group by decreasing the mpap and rvsp, which was associated with suppressed inflammation, apoptosis, and extracellular matrix injury. |
2021-12-04 |
2023-08-13 |
rat |
| Lingli Fang, Yusi Ye, Xi Tan, Lan Huang, Yao H. Overloading stress-induced progressive degeneration and self-repair in condylar cartilage. Annals of the New York Academy of Sciences. vol 1503. issue 1. 2021-12-03. PMID:33962484. |
subsequently, widespread chondrocyte apoptosis was found, followed by new chondrocyte proliferation in aggregates with matrix degradation and subchondral bone catabolism. |
2021-12-03 |
2023-08-13 |
mouse |
| Wen-Yen Huang, Jin-Bon Hong, Michael Chang, Shih-Yi Wang, Shih-Fan Lai, Hsiung-Fei Chien, Sung-Jan Li. Lower proximal cup and outer root sheath cells regenerate hair bulbs during anagen hair follicle repair after chemotherapeutic injury. Experimental dermatology. vol 30. issue 4. 2021-12-01. PMID:32781495. |
hair bulbs first shrunk due to matrix cell apoptosis associated with dna double-strand breaks. |
2021-12-01 |
2023-08-13 |
mouse |
| Ayako Yumine, Gaku Tsuj. Hydroxychloroquine induces matrix metalloproteinase 1 expression and apoptosis in neurofibromatosis type 1 Schwann cells. Journal of dermatological science. vol 104. issue 2. 2021-12-01. PMID:34763989. |
hydroxychloroquine induces matrix metalloproteinase 1 expression and apoptosis in neurofibromatosis type 1 schwann cells. |
2021-12-01 |
2023-08-13 |
Not clear |
| Jia-Hao Ni, Wan-Xi Yan. Extracellular and Intracellular Skeletons: How Do They Involve in Apoptosis. DNA and cell biology. 2021-12-01. PMID:34847739. |
in addition, the regulatory role of extracellular matrix (ecm) fibrous proteins, which can be considered as the extracellular skeleton, in the process of apoptosis is rarely summarized. |
2021-12-01 |
2023-08-13 |
Not clear |
| Benjamin Thoreau, Benjamin Chaigne, Arthur Renaud, Luc Moutho. Pathophysiology of systemic sclerosis. Presse medicale (Paris, France : 1983). vol 50. issue 1. 2021-11-30. PMID:34718115. |
the whole lead to the overactivity of the fibroblast with genetic dysregulation, apoptosis defect, hyperproduction of elements of extracellular matrix, and finally the phenomena of vasculopathy and fibrosis. |
2021-11-30 |
2023-08-13 |
human |