| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ken-Ichi Miyazono, Tomoko Ito, Yui Fukatsu, Hikaru Wada, Akira Kurisaki, Masaru Tanokur. Structural basis for transcriptional coactivator recognition by SMAD2 in TGF-β signaling. Science signaling. vol 13. issue 662. 2021-11-08. PMID:33323411. |
transforming growth factor-β (tgf-β) proteins regulate multiple cellular functions, including cell proliferation, apoptosis, and extracellular matrix formation. |
2021-11-08 |
2023-08-13 |
Not clear |
| Peng Xi, Cai-Lin Zhang, Shi-Yan Wu, Lei Liu, Wen-Ju Li, Yi-Mei L. CircRNA circ-IQGAP1 Knockdown Alleviates Interleukin-1β-Induced Osteoarthritis Progression via Targeting miR-671-5p/TCF4. Orthopaedic surgery. vol 13. issue 3. 2021-11-08. PMID:33675175. |
to explore the function of circular rna iq motif-containing gtpase-activating protein 1 (circ-iqgap1) in interleukin (il)-1β-induced osteoarthritis (oa) model and to explore whether circ-iqgap1 can modulate microrna-671-5p (mir-671-5p) and transcription factor 4 (tcf4) to regulate chondrocyte apoptosis, inflammatory injury, and extracellular matrix degradation. |
2021-11-08 |
2023-08-13 |
Not clear |
| Ying-Ying Zhang, Rui-Zhi Tan, Ying Yu, Yang-Yang Niu, Chen Y. LncRNA GAS5 protects against TGF-β-induced renal fibrosis via the Smad3/miRNA-142-5p axis. American journal of physiology. Renal physiology. vol 321. issue 4. 2021-11-08. PMID:34486400. |
taken together, our results uncovered a lncrna/mirna competing endogenous rna network-based mechanism that modulates extracellular matrix formation and cell apoptosis via the smad3 pathway. |
2021-11-08 |
2023-08-13 |
mouse |
| Gaofeng Zhang, Yuanmei Liao, Hanshi Yang, Jian Tao, Lin Ma, Xiaohua Zu. Irigenin reduces the expression of caspase-3 and matrix metalloproteinases, thus suppressing apoptosis and extracellular matrix degradation in TNF-α-stimulated nucleus pulposus cells. Chemico-biological interactions. vol 349. 2021-11-08. PMID:34600870. |
irigenin reduces the expression of caspase-3 and matrix metalloproteinases, thus suppressing apoptosis and extracellular matrix degradation in tnf-α-stimulated nucleus pulposus cells. |
2021-11-08 |
2023-08-13 |
Not clear |
| Caining Wen, Limei Xu, Xiao Xu, Daping Wang, Yujie Liang, Li Dua. Insulin-like growth factor-1 in articular cartilage repair for osteoarthritis treatment. Arthritis research & therapy. vol 23. issue 1. 2021-11-08. PMID:34717735. |
igf-1 is a member of a family of growth factors that are structurally closely related to pro-insulin and can promote chondrocyte proliferation, enhance matrix production, and inhibit chondrocyte apoptosis. |
2021-11-08 |
2023-08-13 |
Not clear |
| Yoon Young Kim, Jun-Won Yun, Sung Woo Kim, Hoon Kim, Byeong-Cheol Kang, Seung-Yup K. Synergistic Promoting Effects of X-Linked Inhibitor of Apoptosis Protein and Matrix on the In Vitro Follicular Maturation of Marmoset Follicles. Tissue engineering and regenerative medicine. 2021-11-06. PMID:34741748. |
synergistic promoting effects of x-linked inhibitor of apoptosis protein and matrix on the in vitro follicular maturation of marmoset follicles. |
2021-11-06 |
2023-08-13 |
mouse |
| Yoon Young Kim, Jun-Won Yun, Sung Woo Kim, Hoon Kim, Byeong-Cheol Kang, Seung-Yup K. Synergistic Promoting Effects of X-Linked Inhibitor of Apoptosis Protein and Matrix on the In Vitro Follicular Maturation of Marmoset Follicles. Tissue engineering and regenerative medicine. 2021-11-06. PMID:34741748. |
in this study, we attempted to establish a 3d matrix (matrtigel)-based ivfm condition for marmoset ovarian follicles in combination with anti-apoptotic factor, x-linked inhibitor of apoptosis protein (xiap). |
2021-11-06 |
2023-08-13 |
mouse |
| Yuan Li, Zhiming Wang, Xiuwen Wu, Gefei Wang, Guosheng Gu, Huajian Ren, Zhiwu Hong, Jianan Re. Intestinal mucosa-derived DNA methylation signatures in the penetrating intestinal mucosal lesions of Crohn's disease. Scientific reports. vol 11. issue 1. 2021-11-02. PMID:33963246. |
differential dna methylation sites were participated in the positive regulation of apoptosis and the positive regulation of il-8 production and were enriched in signaling pathways related to inflammatory bowel disease and extracellular matrix receptor interaction signaling pathways. |
2021-11-02 |
2023-08-13 |
Not clear |
| Yuan Li, Zhiming Wang, Xiuwen Wu, Gefei Wang, Guosheng Gu, Huajian Ren, Zhiwu Hong, Jianan Re. Intestinal mucosa-derived DNA methylation signatures in the penetrating intestinal mucosal lesions of Crohn's disease. Scientific reports. vol 11. issue 1. 2021-11-02. PMID:33963246. |
apoptosis, interleukin-8 production and abnormal extracellular matrix might be involved in the mechanism of penetrating intestinal mucosal lesions in crohn's disease. |
2021-11-02 |
2023-08-13 |
Not clear |
| Yi-Li Zheng, Ge Song, Jia-Bao Guo, Xuan Su, Yu-Meng Chen, Zheng Yang, Pei-Jie Chen, Xue-Qiang Wan. Interactions Among lncRNA/circRNA, miRNA, and mRNA in Musculoskeletal Degenerative Diseases. Frontiers in cell and developmental biology. vol 9. 2021-10-30. PMID:34708047. |
long non-coding rnas (lncrnas) and circular rnas (circrnas) are novel regulators of gene expression that play an important role in biological regulation, involving in chondrocyte proliferation and apoptosis, extracellular matrix degradation and peripheral blood mononuclear cell inflammation. |
2021-10-30 |
2023-08-13 |
Not clear |
| Huajie Mao, Bin Han, Hao Li, Yiqing Tao, Weigang W. FABP4 knockdown suppresses inflammation, apoptosis and extracellular matrix degradation in IL-1β-induced chondrocytes by activating PPARγ to regulate the NF-κB signaling pathway. Molecular medicine reports. vol 24. issue 6. 2021-10-26. PMID:34651666. |
fabp4 knockdown suppresses inflammation, apoptosis and extracellular matrix degradation in il-1β-induced chondrocytes by activating pparγ to regulate the nf-κb signaling pathway. |
2021-10-26 |
2023-08-13 |
Not clear |
| Huajie Mao, Bin Han, Hao Li, Yiqing Tao, Weigang W. FABP4 knockdown suppresses inflammation, apoptosis and extracellular matrix degradation in IL-1β-induced chondrocytes by activating PPARγ to regulate the NF-κB signaling pathway. Molecular medicine reports. vol 24. issue 6. 2021-10-26. PMID:34651666. |
in conclusion, fabp4 knockdown suppressed the inflammation, oxidative stress, apoptosis and extracellular matrix degradation of il‑1β‑induced chondrocytes by activating pparγ to inhibit the nf‑κb signaling pathway. |
2021-10-26 |
2023-08-13 |
Not clear |
| Mostafa Jarahian, Faroogh Marofi, Marwah Suliman Maashi, Mahnaz Ghaebi, Abdolrahman Khezri, Martin R Berge. Re-Expression of Poly/Oligo-Sialylated Adhesion Molecules on the Surface of Tumor Cells Disrupts Their Interaction with Immune-Effector Cells and Contributes to Pathophysiological Immune Escape. Cancers. vol 13. issue 20. 2021-10-26. PMID:34680351. |
this characteristic property correlates with an aggressive clinical phenotype and endows them with multiple roles in biological processes that underlie all steps of cancer progression, including regulation of cell-cell and/or cell-extracellular matrix interactions, as well as increased proliferation, migration, reduced apoptosis rate of tumor cells, angiogenesis, and metastasis. |
2021-10-26 |
2023-08-13 |
Not clear |
| Cheryl M J Tan, Adam J Lewandowski, Wilby Williamson, Odaro J Huckstep, Grace Z Yu, Roman Fischer, Jillian N Simon, Maryam Alsharqi, Afifah Mohamed, Paul Leeson, Mariane Bertagnoll. Proteomic Signature of Dysfunctional Circulating Endothelial Colony-Forming Cells of Young Adults. Journal of the American Heart Association. vol 10. issue 15. 2021-10-22. PMID:34275329. |
hierarchical functional clustering revealed distinct ecfc proteomic signatures between functional and dysfunctional ecfcs with changes in cellular mechanisms involved in exocytosis, vesicle transport, extracellular matrix organization, cell metabolism, and apoptosis. |
2021-10-22 |
2023-08-13 |
human |
| b' Ricardo D Moreno, Paulina Urriola-Mu\\xc3\\xb1oz, Ra\\xc3\\xbal Lagos-Cabr\\xc3\\xa. The emerging role of matrix metalloproteases of the ADAM family in male germ cell apoptosis. Spermatogenesis. vol 1. issue 3. 2021-10-21. PMID:22319668.' |
the emerging role of matrix metalloproteases of the adam family in male germ cell apoptosis. |
2021-10-21 |
2023-08-12 |
Not clear |
| Sugure Maruta, Yasuyoshi Miyata, Yuji Sagara, Shigeru Kanda, Takahisa Iwata, Shin-Ichi Watanabe, Hideki Sakai, Tomayoshi Hayashi, Hiroshi Kanetak. Expression of matrix metalloproteinase-10 in non-metastatic prostate cancer: Correlation with an imbalance in cell proliferation and apoptosis. Oncology letters. vol 1. issue 3. 2021-10-21. PMID:22966318. |
expression of matrix metalloproteinase-10 in non-metastatic prostate cancer: correlation with an imbalance in cell proliferation and apoptosis. |
2021-10-21 |
2023-08-12 |
human |
| Uzma Minhas, Tracey A Martin, Fiona Ruge, Keith G Harding, Wen G Jian. Pattern of expression of CCN family members Cyr61, CTGF and NOV in human acute and chronic wounds. Experimental and therapeutic medicine. vol 2. issue 4. 2021-10-21. PMID:22977554. |
collectively, these proteins stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest and migration, and regulate angiogenesis, tumour growth, placentation, implantation, embryogenesis and endochondral ossification. |
2021-10-21 |
2023-08-12 |
human |
| Ping Zhang, Jiao Tan, DA-Bing Yang, Zi-Chao Luo, Shan Luo, Ping Chen, Ping Sun, Yi Zhou, Xian-Cheng Chen, Yu-Quan Wei, Yan-Jun We. Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma. Experimental and therapeutic medicine. vol 4. issue 5. 2021-10-21. PMID:23226739. |
vesicular stomatitis virus (vsv) matrix protein (mp) induces the apoptosis of tumor cells in the absence of other viral components. |
2021-10-21 |
2023-08-12 |
mouse |
| Danika M Hayman, Yangming Xiao, Qingping Yao, Zonglai Jiang, Merry L Lindsey, Hai-Chao Ha. Alterations in Pulse Pressure Affect Artery Function. Cellular and molecular bioengineering. vol 5. issue 4. 2021-10-21. PMID:23243477. |
vasomotor response, wall permeability, cell proliferation, apoptosis, extracellular matrix remodeling, and proteins involved in atherogenesis were examined. |
2021-10-21 |
2023-08-12 |
Not clear |
| Guo-Jun Xu, Tian-Yi Gan, Bao-Peng Tang, Zu-Heng Chen, Ailiman Mahemuti, Tao Jiang, Jian-Guo Song, Xia Guo, Yao-Dong Li, Hai-Jun Miao, Xian-Hui Zhou, Yu Zhang, Jin-Xin L. Accelerated fibrosis and apoptosis with ageing and in atrial fibrillation: Adaptive responses with maladaptive consequences. Experimental and therapeutic medicine. vol 5. issue 3. 2021-10-21. PMID:23403858. |
the aim of this study was to investigate whether abnormal expression of matrix metalloproteinase (mmp)-9/tissue inhibitors of mmps (timp)-1 and b cell lymphoma 2 (bcl-2)/bcl-2-associated x protein (bax) are correlated with the characteristic accelerated fibrosis and apoptosis during ageing and in atrial fibrillation (af). |
2021-10-21 |
2023-08-12 |
Not clear |