| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhaoping Che, Jie Xueqin, Zongyu Zhan. LncRNA OIP5-AS1 accelerates intervertebral disc degeneration by targeting miR-25-3p. Bioengineered. vol 12. issue 2. 2021-12-07. PMID:34872452. |
after oip5-as1 was silenced, cell proliferation was boosted whereas both apoptosis and extracellular matrix (ecm) degradation were restrained. |
2021-12-07 |
2023-08-13 |
Not clear |
| Greg J Beite. Organ remodeling: The molecular choreography of a dance of destruction. Current biology : CB. vol 31. issue 23. 2021-12-07. PMID:34875239. |
a new study reveals that the drosophila tracheal system is disassembled during pupation via ecdysone-dependent remodeling of the extracellular matrix, which then signals through the hippo-yorkie/yap network to induce apoptosis. |
2021-12-07 |
2023-08-13 |
drosophila_melanogaster |
| Viktor Zaykov, Brahim Chaqou. The CCN2/CTGF interactome: an approach to understanding the versatility of CCN2/CTGF molecular activities. Journal of cell communication and signaling. vol 15. issue 4. 2021-12-06. PMID:34613590. |
cellular communication network 2 (ccn2), also known as connective tissue growth factor (ctgf) regulates diverse cellular processes, some at odds with others, including adhesion, proliferation, apoptosis, and extracellular matrix (ecm) protein synthesis. |
2021-12-06 |
2023-08-13 |
Not clear |
| Chun-Min Su, Song-Shei Lin, Hsiao-Chia Wang, Fei-Ting Hsu, Jing Gung Chung, Li-Cho Hs. The inhibitory effect and mechanism of quetiapine on tumor progression in hepatocellular carcinoma in vivo. Environmental toxicology. vol 37. issue 1. 2021-12-06. PMID:34626444. |
extracellular signal-regulated kinases (erks) and nuclear factor-κb (nf-κb) mediated downstream proteins, such as myeloid leukemia cell differentiation protein (mcl-1), cellular flice-inhibitory protein (c-flip), x-linked inhibitor of apoptosis protein (xiap), cyclin-d1, matrix metallopeptidase 9 (mmp-9), vascular endothelial growth factor-a (vegf-a) and indoleamine 2,3-dioxygenase (ido) which involved in proliferation, survival, angiogenesis, invasion and anti-tumor immunity were all decreased by quetiapine. |
2021-12-06 |
2023-08-13 |
Not clear |
| b' Aleksandra Augu\\xc5\\x9bciak-Duma, Marta Lesiak, Karolina St\\xc4\\x99pie\\xc5\\x84, Ewa Gutmajster, Aleksander L Siero\\xc5\\x8. mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report. Acta biochimica Polonica. vol 68. issue 4. 2021-12-06. PMID:34669362.' |
abdominal aortic aneurysm is a process involving the disruption and reconstruction of the extracellular matrix and the apoptosis of smooth muscle cells under the strong influence of the immune system. |
2021-12-06 |
2023-08-13 |
human |
| Ellen E Quillen, Jaydee Foster, Anne Sheldrake, Maggie Stainback, Jeremy Glenn, Laura A Cox, Todd L Bredbenne. Circulating miRNAs associated with bone mineral density in healthy adult baboons. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2021-12-04. PMID:34799865. |
we suggest that these mirnas are involved in the regulation of cellular proliferation, apoptosis, and protein composition in the extracellular matrix throughout life; and age-related dysregulation of these systems may lead to disease. |
2021-12-04 |
2023-08-13 |
human |
| Hua Guan, Xiaofeng Yang, Tao Shi, Yongjian Zhang, Aoqi Xiang, Yongxin L. CTRP9 Mitigates the Progression of Arteriovenous Shunt-Induced Pulmonary Artery Hypertension in Rats. Cardiovascular therapeutics. vol 2021. 2021-12-04. PMID:34858521. |
ctrp9 attenuated the pulmonary vascular remodeling in the shunt group by decreasing the mpap and rvsp, which was associated with suppressed inflammation, apoptosis, and extracellular matrix injury. |
2021-12-04 |
2023-08-13 |
rat |
| Lingli Fang, Yusi Ye, Xi Tan, Lan Huang, Yao H. Overloading stress-induced progressive degeneration and self-repair in condylar cartilage. Annals of the New York Academy of Sciences. vol 1503. issue 1. 2021-12-03. PMID:33962484. |
subsequently, widespread chondrocyte apoptosis was found, followed by new chondrocyte proliferation in aggregates with matrix degradation and subchondral bone catabolism. |
2021-12-03 |
2023-08-13 |
mouse |
| Wen-Yen Huang, Jin-Bon Hong, Michael Chang, Shih-Yi Wang, Shih-Fan Lai, Hsiung-Fei Chien, Sung-Jan Li. Lower proximal cup and outer root sheath cells regenerate hair bulbs during anagen hair follicle repair after chemotherapeutic injury. Experimental dermatology. vol 30. issue 4. 2021-12-01. PMID:32781495. |
hair bulbs first shrunk due to matrix cell apoptosis associated with dna double-strand breaks. |
2021-12-01 |
2023-08-13 |
mouse |
| Ayako Yumine, Gaku Tsuj. Hydroxychloroquine induces matrix metalloproteinase 1 expression and apoptosis in neurofibromatosis type 1 Schwann cells. Journal of dermatological science. vol 104. issue 2. 2021-12-01. PMID:34763989. |
hydroxychloroquine induces matrix metalloproteinase 1 expression and apoptosis in neurofibromatosis type 1 schwann cells. |
2021-12-01 |
2023-08-13 |
Not clear |
| Jia-Hao Ni, Wan-Xi Yan. Extracellular and Intracellular Skeletons: How Do They Involve in Apoptosis. DNA and cell biology. 2021-12-01. PMID:34847739. |
in addition, the regulatory role of extracellular matrix (ecm) fibrous proteins, which can be considered as the extracellular skeleton, in the process of apoptosis is rarely summarized. |
2021-12-01 |
2023-08-13 |
Not clear |
| Benjamin Thoreau, Benjamin Chaigne, Arthur Renaud, Luc Moutho. Pathophysiology of systemic sclerosis. Presse medicale (Paris, France : 1983). vol 50. issue 1. 2021-11-30. PMID:34718115. |
the whole lead to the overactivity of the fibroblast with genetic dysregulation, apoptosis defect, hyperproduction of elements of extracellular matrix, and finally the phenomena of vasculopathy and fibrosis. |
2021-11-30 |
2023-08-13 |
human |
| Cheng-Tien Wu, Man-Chih Chen, Shing-Hwa Liu, Ting-Hua Yang, Lin-Hwa Long, Siao-Syun Guan, Chang-Mu Che. Bioactive Flavonoids Icaritin and Icariin Protect against Cerebral Ischemia-Reperfusion-Associated Apoptosis and Extracellular Matrix Accumulation in an Ischemic Stroke Mouse Model. Biomedicines. vol 9. issue 11. 2021-11-30. PMID:34829948. |
bioactive flavonoids icaritin and icariin protect against cerebral ischemia-reperfusion-associated apoptosis and extracellular matrix accumulation in an ischemic stroke mouse model. |
2021-11-30 |
2023-08-13 |
mouse |
| Ola Habanjar, Mona Diab-Assaf, Florence Caldefie-Chezet, Laetitia Delor. 3D Cell Culture Systems: Tumor Application, Advantages, and Disadvantages. International journal of molecular sciences. vol 22. issue 22. 2021-11-30. PMID:34830082. |
the 3d matrix presents a highly dynamic framework where its components are deposited, degraded, or modified to delineate functions and provide a platform where cells attach to perform their specific functions, including adhesion, proliferation, communication, and apoptosis. |
2021-11-30 |
2023-08-13 |
Not clear |
| Kaei Nasu, Yoko Aoyagi, Ruofei Zhu, Mamiko Okamoto, Kentaro Kai, Yasushi Kawan. Promising therapeutic targets of endometriosis obtained from microRNA studies. Medical molecular morphology. 2021-11-30. PMID:34846581. |
most of the overexpressed mirnas induced endometriosis-specific characteristics including inhibition of apoptosis and decidualization, upregulation of fibrogenesis, invasion, migration, cell proliferation, attachment to extracellular matrix, inflammation, and angiogenesis in the endometriotic cells. |
2021-11-30 |
2023-08-13 |
Not clear |
| Dylan O'Toole, Ali Abdullah I Zaeri, Stuart A Nicklin, Anne T French, Christopher M Loughrey, Tamara P Marti. Signalling pathways linking cysteine cathepsins to adverse cardiac remodelling. Cellular signalling. vol 76. 2021-11-29. PMID:32891693. |
cysteine cathepsins contribute to key signalling pathways involved in adverse cardiac remodelling including synthesis and degradation of the cardiac extracellular matrix (ecm), cardiomyocyte hypertrophy, impaired cardiomyocyte contractility and apoptosis. |
2021-11-29 |
2023-08-13 |
Not clear |
| Yanhong Liu, Hongguang Nie, Yan Ding, Yapeng Hou, Kejun Mao, Yong Cu. MiRNA, a New Treatment Strategy for Pulmonary Fibrosis. Current drug targets. vol 22. issue 7. 2021-11-29. PMID:32988351. |
micrornas (mirnas) are a class of small non-coding rnas that are involved in many essential cellular processes, including extracellular matrix remodeling, alveolar epithelial cell apoptosis, epithelial-mesenchymal transition, etc. |
2021-11-29 |
2023-08-13 |
Not clear |
| Alper Yalçın, Ali Güre. Effects of N-acetylcysteine on kidney tissue, matrix metalloproteinase-2, irisin and oxidative stress in a diabetes mellitus model. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 96. issue 8. 2021-11-29. PMID:33596748. |
we investigated the possible effects of the antioxidant, n-acetylcysteine (nac), on kidney morphology, apoptosis, matrix metalloproteinase-2 (mmp2) activity, irisin levels and oxidative stress in an experimental dm model. |
2021-11-29 |
2023-08-13 |
rat |
| Jinjiang Yang, Ai Guo, Qiang Li, Jie W. Platelet-rich plasma attenuates interleukin-1β-induced apoptosis and inflammation in chondrocytes through targeting hypoxia-inducible factor-2α. Tissue & cell. vol 73. 2021-11-29. PMID:34536814. |
in addition, cell apoptosis markers, matrix metalloproteinase (mmp)-1, 3, -9 and -13, and extracellular matrix-related genes were evaluated. |
2021-11-29 |
2023-08-13 |
rat |
| Jinjiang Yang, Ai Guo, Qiang Li, Jie W. Platelet-rich plasma attenuates interleukin-1β-induced apoptosis and inflammation in chondrocytes through targeting hypoxia-inducible factor-2α. Tissue & cell. vol 73. 2021-11-29. PMID:34536814. |
interestingly, 10% prp protected chondrocytes against il-1β-induced apoptosis and matrix degradation, and meanwhile suppressed the hif-2α activation. |
2021-11-29 |
2023-08-13 |
rat |