| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shaojiong Zhou, Shuo Liu, Xiaoqiang Liu, Weiduan Zhuan. Bioinformatics Gene Analysis of Potential Biomarkers and Therapeutic Targets for Unstable Atherosclerotic Plaque-Related Stroke. Journal of molecular neuroscience : MN. vol 71. issue 5. 2021-11-19. PMID:33155176. |
inflammation, immunity, extracellular matrix degradation, blood coagulation, apoptosis and nerve degeneration were the primary physiopathological processes in uap-related stroke. |
2021-11-19 |
2023-08-13 |
Not clear |
| Fabrizio Luppi, Meena Kalluri, Paola Faverio, Michael Kreuter, Giovanni Ferrar. Idiopathic pulmonary fibrosis beyond the lung: understanding disease mechanisms to improve diagnosis and management. Respiratory research. vol 22. issue 1. 2021-11-19. PMID:33865386. |
ageing and senescence, through interactions with environmental factors, may contribute to the pathogenesis of ipf by various mechanisms, causing lung epithelium damage and increasing the resistance of myofibroblasts to apoptosis, eventually resulting in extracellular matrix accumulation and pulmonary fibrosis. |
2021-11-19 |
2023-08-13 |
human |
| Zhou Cai, Jianhua Huang, Junxiao Yang, Baihong Pan, Wei Wang, Yangyang Ou, Xianwei Wang, Pu Yan. LncRNA SENCR suppresses abdominal aortic aneurysm formation by inhibiting smooth muscle cells apoptosis and extracellular matrix degradation. Bosnian journal of basic medical sciences. vol 21. issue 3. 2021-11-18. PMID:32903173. |
lncrna sencr suppresses abdominal aortic aneurysm formation by inhibiting smooth muscle cells apoptosis and extracellular matrix degradation. |
2021-11-18 |
2023-08-13 |
Not clear |
| Zhou Cai, Jianhua Huang, Junxiao Yang, Baihong Pan, Wei Wang, Yangyang Ou, Xianwei Wang, Pu Yan. LncRNA SENCR suppresses abdominal aortic aneurysm formation by inhibiting smooth muscle cells apoptosis and extracellular matrix degradation. Bosnian journal of basic medical sciences. vol 21. issue 3. 2021-11-18. PMID:32903173. |
in vivo, overexpression of sencr improved the pathological change in aortic tissues and the damage in arterial wall elastic fibers induced by ang-ii, as well as suppressed ang-ii-induced cell apoptosis and extracellular matrix degradation. |
2021-11-18 |
2023-08-13 |
Not clear |
| Zhou Cai, Jianhua Huang, Junxiao Yang, Baihong Pan, Wei Wang, Yangyang Ou, Xianwei Wang, Pu Yan. LncRNA SENCR suppresses abdominal aortic aneurysm formation by inhibiting smooth muscle cells apoptosis and extracellular matrix degradation. Bosnian journal of basic medical sciences. vol 21. issue 3. 2021-11-18. PMID:32903173. |
overexpression of sencr inhibited aaa formation via inhibition of vsmc apoptosis and extracellular matrix degradation. |
2021-11-18 |
2023-08-13 |
Not clear |
| Qing Wang, Lujing Ying, Bing Wei, Yikui Ji, Yi X. Effects of quercetin on apoptosis and extracellular matrix degradation of chondrocytes induced by oxidative stress-mediated pyroptosis. Journal of biochemical and molecular toxicology. 2021-11-18. PMID:34791735. |
effects of quercetin on apoptosis and extracellular matrix degradation of chondrocytes induced by oxidative stress-mediated pyroptosis. |
2021-11-18 |
2023-08-13 |
rat |
| Qing Wang, Lujing Ying, Bing Wei, Yikui Ji, Yi X. Effects of quercetin on apoptosis and extracellular matrix degradation of chondrocytes induced by oxidative stress-mediated pyroptosis. Journal of biochemical and molecular toxicology. 2021-11-18. PMID:34791735. |
results showed that quercetin could reduce lps-induced c28/i2 cell apoptosis, extracellular matrix (ecm) degradation, and cell pyroptosis, and overexpression of nucleotide-binding domain and leucine-rich-repeat-containing (nlr) family, pyrin domain-containing 3 (nlrp3) revealed that quercetin reduced chondrocyte apoptosis and ecm degradation by inhibiting nlrp3-mediated pyroptosis. |
2021-11-18 |
2023-08-13 |
rat |
| Zheng Zheng, Yan Chen, Yinzhou Wang, Yongkun Li, Qiong Chen. MicroRNA-513b-5p targets COL1A1 and COL1A2 associated with the formation and rupture of intracranial aneurysm. Scientific reports. vol 11. issue 1. 2021-11-17. PMID:34290266. |
the effects of the mir-513b-5p mimic and inhibitor on the proliferation, apoptosis, and death of hasmc and the rip1-rip3-mlkl and matrix metalloproteinase pathways were also explored. |
2021-11-17 |
2023-08-13 |
human |
| Kai Sun, Xingzhi Jing, Jiachao Guo, Xudong Yao, Fengjing Gu. Mitophagy in degenerative joint diseases. Autophagy. vol 17. issue 9. 2021-11-16. PMID:32967533. |
ivdd and oa are similar joint diseases involving the degradation of cartilaginous tissues that are mainly caused by oxidative stress, cell apoptosis and extracellular matrix (ecm) degradation. |
2021-11-16 |
2023-08-13 |
Not clear |
| Suman Dalal, Paige L Shook, Mahipal Singh, Krishna Sing. Cardioprotective Potential of Exogenous Ubiquitin. Cardiovascular drugs and therapy. vol 35. issue 6. 2021-11-15. PMID:32910339. |
recent studies provide evidence for cardioprotective potential of exogenous ub in the remodeling process of the heart in ihd, including effects on cardiac myocyte apoptosis, inflammatory response, and reorganization of the vasculature and extracellular matrix. |
2021-11-15 |
2023-08-13 |
Not clear |
| Kaiqiang Sun, Jian Zhu, Jingchuan Sun, Xiaofei Sun, Le Huan, Bin Zhang, Feng Lin, Bing Zheng, Jialin Jiang, Xi Luo, Ximing Xu, Jiangang Sh. Neuropeptide Y prevents nucleus pulposus cells from cell apoptosis and IL‑1β‑induced extracellular matrix degradation. Cell cycle (Georgetown, Tex.). vol 20. issue 10. 2021-11-15. PMID:33966606. |
neuropeptide y prevents nucleus pulposus cells from cell apoptosis and il‑1β‑induced extracellular matrix degradation. |
2021-11-15 |
2023-08-13 |
human |
| Kaiqiang Sun, Jian Zhu, Jingchuan Sun, Xiaofei Sun, Le Huan, Bin Zhang, Feng Lin, Bing Zheng, Jialin Jiang, Xi Luo, Ximing Xu, Jiangang Sh. Neuropeptide Y prevents nucleus pulposus cells from cell apoptosis and IL‑1β‑induced extracellular matrix degradation. Cell cycle (Georgetown, Tex.). vol 20. issue 10. 2021-11-15. PMID:33966606. |
rat nucleus pulposus (np) cells were used to investigate the effect of npy on the proliferation, apoptosis, and extracellular matrix (ecm) in np cell induced by il-1βin vitro. |
2021-11-15 |
2023-08-13 |
human |
| Ruihua Jing, Conghui Hu, Tiantian Qi, Jiaqi Yue, Guangyan Wang, Ming Zhang, Chan Wen, Cheng Pei, Bo M. FILIP1L-mediated cell apoptosis, epithelial-mesenchymal transition and extracellular matrix synthesis aggravate posterior capsular opacification. Life sciences. vol 286. 2021-11-15. PMID:34666037. |
filip1l-mediated cell apoptosis, epithelial-mesenchymal transition and extracellular matrix synthesis aggravate posterior capsular opacification. |
2021-11-15 |
2023-08-13 |
rabbit |
| Kyueng-Whan Min, Dong-Hoon Kim, Yung-Kyun Noh, Byoung Kwan Son, Mi Jung Kwon, Ji-Yong Moo. Cancer-associated fibroblasts are associated with poor prognosis in solid type of lung adenocarcinoma in a machine learning analysis. Scientific reports. vol 11. issue 1. 2021-11-11. PMID:34408230. |
in the pathway analyses, cafs were related to blood vessel remodeling, matrix organization, negative regulation of apoptosis and transforming growth factor-β signaling. |
2021-11-11 |
2023-08-13 |
Not clear |
| Hyo-Jun Kim, Jin-Haeng Lee, Sung-Yup Cho, Ju-Hong Jeon, In-Gyu Ki. Transglutaminase 2 mediates transcriptional regulation through BAF250a polyamination. Genes & genomics. vol 43. issue 4. 2021-11-10. PMID:33555506. |
transglutaminase 2 (tg2) mediates protein modifications by crosslinking or by incorporating polyamine in response to oxidative or dna-damaging stress, thereby regulating apoptosis, extracellular matrix formation, and inflammation. |
2021-11-10 |
2023-08-13 |
Not clear |
| Weiyi Qu, Tengfei Ma, Jingjing Cai, Xiaojing Zhang, Peng Zhang, Zhigang She, Feng Wan, Hongliang L. Liver Fibrosis and MAFLD: From Molecular Aspects to Novel Pharmacological Strategies. Frontiers in medicine. vol 8. 2021-11-10. PMID:34746195. |
in this review, we cover recent discoveries in new targets and molecules for antifibrotic treatment, which target pathways intertwined with the fibrogenesis process, including lipid metabolism, inflammation, cell apoptosis, oxidative stress, and extracellular matrix formation. |
2021-11-10 |
2023-08-13 |
Not clear |
| Jian Dong, Kai-Jia Zhang, Gao-Cai Li, Xing-Ren Chen, Jia-Jia Lin, Jia-Wei Li, Zhong-Yang Lv, Zhao-Zhi Deng, Jin Dai, Wangsen Cao, Qing Jian. CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dependent autophagy. Acta pharmacologica Sinica. 2021-11-10. PMID:34754093. |
we showed that cddo-im (20 nm) significantly alleviated tnf-α-induced apoptosis of primary human chondrocytes and extracellular matrix degradation. |
2021-11-10 |
2023-08-13 |
mouse |
| Zuo-Long Wu, Qi-Qi Xie, Tai-Cong Liu, Xing Yang, Guang-Zhi Zhang, Hai-Hong Zhan. Role of the Wnt pathway in the formation, development, and degeneration of intervertebral discs. Pathology, research and practice. vol 220. 2021-11-09. PMID:33647863. |
however, the activation of the wnt pathway after birth promotes ivd cell senescence, apoptosis, and degradation of the extracellular matrix and induces the production of inflammatory factors, thereby accelerating the ivdd process. |
2021-11-09 |
2023-08-13 |
Not clear |
| Hongwei Lu, Chao Jia, Dengying Wu, Haidong Jin, Zeng Lin, Jun Pan, Xiucui Li, Wei Wan. Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway. Cell death & disease. vol 12. issue 10. 2021-11-09. PMID:34556628. |
fibroblast growth factor 21 (fgf21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the sirt1-mtor signaling pathway. |
2021-11-09 |
2023-08-13 |
Not clear |
| Hongwei Lu, Chao Jia, Dengying Wu, Haidong Jin, Zeng Lin, Jun Pan, Xiucui Li, Wei Wan. Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway. Cell death & disease. vol 12. issue 10. 2021-11-09. PMID:34556628. |
in vitro, the results revealed that fgf21 administration alleviated apoptosis, senescence, and extracellular matrix (ecm) catabolism of the chondrocytes induced by tert-butyl hydroperoxide (tbhp) by mediating autophagy flux. |
2021-11-09 |
2023-08-13 |
Not clear |