| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jamal J Shahri, Shirin Saberianpour, Saeed N Bayeg. Comparison of tissue biomarkers in arterial and vein (arteriovenous fistula) aneurysms. Phlebology. 2022-03-08. PMID:35255762. |
aneurysms are distinguished by inflammation, matrix degradation, and apoptosis of smooth muscle cells. |
2022-03-08 |
2023-08-13 |
Not clear |
| Cong-Qiu Ch. Highlights of Strategies Targeting Fibroblasts for Novel Therapies for Rheumatoid Arthritis. Frontiers in medicine. vol 9. 2022-03-07. PMID:35252279. |
exploring fibroblast targeted therapies have been focused on inducing cell death via fibroblast associated proteins; interrupting fibroblast binding to matrix protein; blocking intercellular signaling between fibroblasts and endothelial cells; inhibiting fibroblast proliferation and invasion; promoting cell apoptosis and inducing cellular senescence, and modulating fibroblast glucose metabolism. |
2022-03-07 |
2023-08-13 |
Not clear |
| Tao-Cheng Wu, Wei-Hung Chang, Hsin-Ying Lu, Chun-Che Shi. Tolvaptan reduces angiotensin II-induced experimental abdominal aortic aneurysm and dissection. Vascular pharmacology. 2022-03-01. PMID:35227907. |
in vitro study showed that tolvaptan suppressed matrix metalloproteinase (mmp) expressions (mmp-2 and mmp-9) and apoptosis in ang ii-stimulated hasmcs. |
2022-03-01 |
2023-08-13 |
mouse |
| Dong Chen, Xin Jian. Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1. Experimental cell research. 2022-03-01. PMID:35231441. |
the study aimed to explore the effects of normal cesc-derived exosomes (n-cesc-exo) on autophagy, apoptosis and extracellular matrix (ecm) metabolism of nucleus pulposus cells (npcs) and their underlying molecular mechanisms in vivo and in vitro. |
2022-03-01 |
2023-08-13 |
Not clear |
| Zirui Yu, Fei Cong, Wentao Zhang, Tao Song, Shihui Zhang, Renqi Jian. Circular RNA circ_0020014 contributes to osteoarthritis progression via miR-613/ADAMTS5 axis. Bosnian journal of basic medical sciences. 2022-02-28. PMID:35225755. |
il-1β treatment induced cell injury by promoting inflammation and apoptosis, and inhibiting cell viability and extracellular matrix (ecm) accumulation in chondrocytes. |
2022-02-28 |
2023-08-13 |
Not clear |
| Yawei Zhang, Hengheng Zheng, Baitong L. Circ_0110251 overexpression alleviates IL-1β-induced chondrocyte apoptosis and extracellular matrix degradation by regulating miR-3189-3p/SPRY1 axis in osteoarthritis. Autoimmunity. 2022-02-24. PMID:35196925. |
circ_0110251 overexpression alleviates il-1β-induced chondrocyte apoptosis and extracellular matrix degradation by regulating mir-3189-3p/spry1 axis in osteoarthritis. |
2022-02-24 |
2023-08-13 |
human |
| Chukwuebuka ThankGod Eze, Obianuju Oluchukwu Eze, Tochukwu Ernest Ugochukwu, Nnamdi Henry Amaeze, Emeka Bright Ogbuene, Adebayo Akeem Otitoloj. In vitro cytotoxic assessment of e-waste-related chemical pollution in impacted soil matrix. Environmental monitoring and assessment. vol 194. issue 3. 2022-02-23. PMID:35194689. |
in addition, toxicity mechanisms such as apoptosis, necrosis and necroptosis were analysed in order to determine the effect of the actual chemical mixture present in the e-waste soil matrix. |
2022-02-23 |
2023-08-13 |
Not clear |
| Haoxi Li, Wenhao Li, Li Zhang, Jicheng He, Lin Tang, Zhuhai Li, Feng Chen, Qie Fan, Jianxun We. Comprehensive Network Analysis Identified SIRT7, NTRK2, and CHI3L1 as New Potential Markers for Intervertebral Disc Degeneration. Journal of oncology. vol 2022. 2022-02-22. PMID:35190738. |
functional enrichment analysis showed that the red module was mainly related to neutrophil activation and regulation of cytokine-mediated signaling pathway and apoptosis, whereas the midnightblue module was mainly related to extracellular matrix organization, bone development, extracellular matrix, extracellular matrix component, and other extracellular matrices. |
2022-02-22 |
2023-08-13 |
Not clear |
| Jin Yang, Qi Li, Tingting Wang, Ke L. Circular RNA triple functional domain promotes osteoarthritis' development by modulating the microRNA-136-5p/Nicotinamide phosphoribosyltransferase axis. Bioengineered. vol 13. issue 3. 2022-02-22. PMID:35191807. |
knockdown circtrio facilitates chondrocyte viability, but suppresses the inflammation, the apoptosis, and matrix metalloproteinases (mmp)-3 and mmp-13 expression, whereas up-regulation aggravates oa. |
2022-02-22 |
2023-08-13 |
rat |
| Hao Li, Lijun Tian, Jianhua Li, Yongjin Li, Lilong Du, Zhenxin Huo, Baoshan X. The Roles of circRNAs in Intervertebral Disc Degeneration: Inflammation, Extracellular Matrix Metabolism, and Apoptosis. Analytical cellular pathology (Amsterdam). vol 2022. 2022-02-21. PMID:35186669. |
the roles of circrnas in intervertebral disc degeneration: inflammation, extracellular matrix metabolism, and apoptosis. |
2022-02-21 |
2023-08-13 |
human |
| Hao Li, Lijun Tian, Jianhua Li, Yongjin Li, Lilong Du, Zhenxin Huo, Baoshan X. The Roles of circRNAs in Intervertebral Disc Degeneration: Inflammation, Extracellular Matrix Metabolism, and Apoptosis. Analytical cellular pathology (Amsterdam). vol 2022. 2022-02-21. PMID:35186669. |
circular rnas (circrnas), as a kind of noncoding rna (ncrna), participate in the regulation of genetic transcription and translation and further affect the expression of inflammatory cytokine, metabolism of extracellular matrix (ecm), the proliferation and apoptosis of cells, etc. |
2022-02-21 |
2023-08-13 |
human |
| Mohammed Razeeth Shait Mohammed, Mazin Zamzami, Hani Choudhry, Firoz Ahmed, Bushra Ateeq, Mohammad Imran Kha. The Histone H3K27me3 Demethylases KDM6A/B Resist Anoikis and Transcriptionally Regulate Stemness-Related Genes. Frontiers in cell and developmental biology. vol 10. 2022-02-21. PMID:35186918. |
epithelial cancer cells that lose attachment from the extracellular matrix (ecm) to seed in a distant organ often undergo anoikis's specialized form of apoptosis. |
2022-02-21 |
2023-08-13 |
Not clear |
| Viktoria Heine, Carina Dey, Pavla Bojarová, Vladimír Křen, Lothar Ellin. Methods of in vitro study of galectin-glycomaterial interaction. Biotechnology advances. 2022-02-21. PMID:35189272. |
galectins are a family of carbohydrate-binding lectins modulating cell events such as cell proliferation, apoptosis, adhesion, or migration by cross-linking the glycan structures of cell membranes and/or extracellular matrix components. |
2022-02-21 |
2023-08-13 |
Not clear |
| Yueyang Tian, Jiaqi Duan, Yang Cao, Huichao Zhou, Ashish D Diwan, Ji T. Bardoxolone Methyl Ameliorates Compression-Induced Oxidative Stress Damage of Nucleus Pulposus Cells and Intervertebral Disc Degeneration Frontiers in bioengineering and biotechnology. vol 9. 2022-02-18. PMID:35178384. |
according to reports, excessive compression is a high-risk factor for idd; compressive stress can induce oxidative stress in nucleus pulposus (np) cells during idd progression that, in turn, promotes cell apoptosis and extracellular matrix (ecm) degradation. |
2022-02-18 |
2023-08-13 |
Not clear |
| Hui Lin, Shuo Tian, Yizhong Peng, Ling Wu, Yan Xiao, Xiangcheng Qing, Zengwu Sha. IGF Signaling in Intervertebral Disc Health and Disease. Frontiers in cell and developmental biology. vol 9. 2022-02-18. PMID:35178405. |
the activation of igf signaling retards ivdd by increasing cell proliferation, promoting extracellular matrix (ecm) synthesis, inhibiting ecm decomposition, and preventing apoptosis and senescence of disc cells. |
2022-02-18 |
2023-08-13 |
Not clear |
| Zilong Zhang, Teng Zhao, Haiwei Xu, Xing W. Circ_0008365 Suppresses Apoptosis, Inflammation and Extracellular Matrix Degradation of IL-1β-treated Chondrocytes in Osteoarthritis by Regulating miR-324-5p/BMPR2/NF-κB Signaling Axis. Immunological investigations. 2022-02-17. PMID:35172669. |
circ_0008365 suppresses apoptosis, inflammation and extracellular matrix degradation of il-1β-treated chondrocytes in osteoarthritis by regulating mir-324-5p/bmpr2/nf-κb signaling axis. |
2022-02-17 |
2023-08-13 |
Not clear |
| Xiao-Chuan Li, Shao-Jian Luo, Wu Fan, Tian-Li Zhou, Chun-Ming Huang, Mao-Sheng Wan. M2 macrophage-conditioned medium inhibits intervertebral disc degeneration in a tumor necrosis factor-α-rich environment. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2022-02-16. PMID:35170802. |
after 2-14 days, cell proliferation, extracellular matrix synthesis, apoptosis, and npc senescence were assessed. |
2022-02-16 |
2023-08-13 |
mouse |
| Xiao-Chuan Li, Shao-Jian Luo, Wu Fan, Tian-Li Zhou, Chun-Ming Huang, Mao-Sheng Wan. M2 macrophage-conditioned medium inhibits intervertebral disc degeneration in a tumor necrosis factor-α-rich environment. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2022-02-16. PMID:35170802. |
therefore, co-culture with m2cm promotes cell proliferation and extracellular matrix synthesis and inhibits inflammation, apoptosis, and npc senescence. |
2022-02-16 |
2023-08-13 |
mouse |
| Verónica A García-García, Josefa P Alameda, Angustias Page, Antonio Mérida-García, Manuel Navarro, Adrián Tejero, Jesús M Paramio, Rosa A García-Fernández, M Llanos Casanov. IKKα Induces Epithelial-Mesenchymal Changes in Mouse Skin Carcinoma Cells That Can Be Partially Reversed by Apigenin. International journal of molecular sciences. vol 23. issue 3. 2022-02-15. PMID:35163299. |
these emt-related changes include a shift toward a migratory phenotype and induction of the expression of proteins involved in cell matrix degradation, cell survival and resistance to apoptosis. |
2022-02-15 |
2023-08-13 |
mouse |
| Gilda Aiello, Francesca Rescigno, Marisa Meloni, Giovanna Baron, Giancarlo Aldini, Marina Carini, Alfonsina D'Amat. Oxidative Stress Modulation by Carnosine in Scaffold Free Human Dermis Spheroids Model: A Proteomic Study. International journal of molecular sciences. vol 23. issue 3. 2022-02-15. PMID:35163388. |
of the several modulated pathways, most are involved in mitochondrial functionality, such as oxidative phosphorylation, tca cycle, extracellular matrix reorganization and apoptosis. |
2022-02-15 |
2023-08-13 |
human |