| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Junjun Mao, Xinping Wang, Minghui Yu, Chenkun Su. Effects of Atractylon on Proliferation and Apoptosis of Intestinal Cancer Cells Through PI3K/AKT/mTOR Signaling Pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 5. 2022-08-27. PMID:36029491. |
the content of interferon-γ (inf-γ), tumor necrosis factor-α (tnf-α) and matrix metalloproteinase-9 (mmp-9) was detected via enzyme-linked immunosorbent assay (elisa), and the apoptosis of ht29 cells was detected through terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) staining. |
2022-08-27 |
2023-08-14 |
Not clear |
| Paulina Borzdziłowska, Ilona Bednare. Alpha Mangostin and Cisplatin as Modulators of Exosomal Interaction of Ovarian Cancer Cell with Fibroblasts. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012171. |
in our study, we observed altered expression of genes involved in various steps of the metastasis process (including genes related to cell adhesion, genes related to the interaction with the extracellular matrix, the cell cycle, cell growth and proliferation, and apoptosis). |
2022-08-26 |
2023-08-14 |
human |
| Taneli T Mattila, Madhura Patankar, Juha P Väyrynen, Kai Klintrup, Jyrki Mäkelä, Anne Tuomisto, Pentti Nieminen, Markus J Mäkinen, Tuomo J Karttune. Putative anoikis resistant subpopulations are enriched in lymph node metastases and indicate adverse prognosis in colorectal carcinoma. Clinical & experimental metastasis. 2022-08-26. PMID:36018456. |
anoikis refers to apoptosis induced by the loss of contact with the extracellular matrix. |
2022-08-26 |
2023-08-14 |
Not clear |
| Suhnrita Chaudhuri, Sagar Acharya, Swapna Chaudhur. Therapeutic intervention of glioma with the novel antineoplastic agent T11TS: the story so far. Immunotherapy. 2022-08-25. PMID:36004447. |
t11ts hinders endothelial cell progression and metastasis by arresting matrix degradation, inhibiting the ras-raf and akt-pten pathways and initiating inflammatory changes, causing apoptosis. |
2022-08-25 |
2023-08-14 |
Not clear |
| Argen Mamazhakypov, Meerim Sartmyrzaeva, Akpay Sh Sarybaev, Ralph Schermuly, Akylbek Sydyko. Clinical and Molecular Implications of Osteopontin in Heart Failure. Current issues in molecular biology. vol 44. issue 8. 2022-08-25. PMID:36005141. |
osteopontin influences myocardial remodeling by regulating extracellular matrix production, the activity of matrix metalloproteinases and various growth factors, inflammatory cell recruitment, myofibroblast differentiation, cardiomyocyte apoptosis, and myocardial vascularization. |
2022-08-25 |
2023-08-14 |
Not clear |
| Yiqiu Liu, Ye Liu, Junyu Deng, Xingqian Wu, Wenjie He, Xingrui Mu, Xuqiang Ni. Molecular mechanisms of Marine-Derived Natural Compounds as photoprotective strategies. International immunopharmacology. vol 111. 2022-08-23. PMID:35998505. |
excessive exposure of the skin to ultraviolet radiation (uvr) causes oxidative stress, inflammation, immunosuppression, apoptosis, and changes in the extracellular matrix, which lead to the development of photoaging and photodamage of skin. |
2022-08-23 |
2023-08-14 |
Not clear |
| Yiqiu Liu, Ye Liu, Junyu Deng, Xingqian Wu, Wenjie He, Xingrui Mu, Xuqiang Ni. Molecular mechanisms of Marine-Derived Natural Compounds as photoprotective strategies. International immunopharmacology. vol 111. 2022-08-23. PMID:35998505. |
it reviews the positive effects of mdncs in counteracting uv-induced oxidative stress, inflammation, dna damage, apoptosis, immunosuppression, and extracellular matrix degradation. |
2022-08-23 |
2023-08-14 |
Not clear |
| Cheng-Chen Zhang, Ting Wu, Li Guan, Yu-Jue Wang, Rui-Qin Yao, Dian-Shuai Gao, Feng L. Effects of STAT3 Inhibitor BP-1-102 on The Proliferation, Invasiveness, Apoptosis and Neurosphere Formation of Glioma Cells in Vitro. Cell biochemistry and biophysics. 2022-08-22. PMID:35994220. |
furthermore, bp-1-102 inhibited the invasion and migration abilities of u251 and a172 cells by decreasing the expression of matrix metallopeptidase 9, and induced glioma cell apoptosis by decreasing the expression of b-cell lymphoma-2. |
2022-08-22 |
2023-08-14 |
Not clear |
| Yusheng Li, Wenqing Xie, Yizi Zheng, Hengzhen Li, Zeqin Wen, Chen Wang, Siyu Chen, Zhenhan Den. The miR-548d-5p/SP1 signaling axis regulates chondrocyte proliferation and inflammatory responses in osteoarthritis. International immunopharmacology. vol 110. 2022-08-18. PMID:35978504. |
mir-548d-5p overexpression partially reversed il-1β-induced chondrocyte damage in vitro, evidenced by the promotion of cell growth, the inhibition of apoptosis and inflammatory cytokine release, and the improvement in extracellular matrix (ecm) deposition. |
2022-08-18 |
2023-08-14 |
rat |
| Qian Xiang, Yongzhao Zhao, Jialiang Lin, Shuai Jiang, Weishi L. The Nrf2 antioxidant defense system in intervertebral disc degeneration: Molecular insights. Experimental & molecular medicine. 2022-08-17. PMID:35978054. |
the nrf2 antioxidant defense system regulates cell apoptosis, senescence, extracellular matrix (ecm) metabolism, the inflammatory response of the nucleus pulposus (np), and calcification of the cartilaginous endplates (ep) in idd. |
2022-08-17 |
2023-08-14 |
cat |
| Marjan Aghajani, Alireza Imani, Gholamali Kardar, Mahdieh Faghihi, Mozhgan Aghajan. Unfavorable Left Ventricular Remodeling due to Experience of Chronic Sleep Restriction after Myocardial Infarction: The role of Matrix Metalloproteinases & Oxidative stress. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 2022-08-02. PMID:35917906. |
herein, we proposed that experience of sleep disruption and/or restriction after myocardial infarction (mi) may aggrevate cardiac extracellular matrix remodeling and induce apoptosis in the cardiomyocytes. |
2022-08-02 |
2023-08-14 |
rat |
| Hossam El-Sheikh Ali, Kirsten Scoggin, Harutaka Murase, Jamie Norris, Bruno Menarim, Pouya Dini, Barry Bal. Transcriptomic and histochemical analysis reveal the complex regulatory networks in equine Chorioallantois during spontaneous term labor. Biology of reproduction. 2022-08-01. PMID:35913756. |
also, tl was associated with the upregulation of matrix metalloproteinase (mmp1, mmp2, mmp3, and mmp9) with subsequent extracellular matrix degradation and apoptosis, as reflected by upregulation of several apoptosis-related genes (atf3, atf4, fas, fos, and birc3). |
2022-08-01 |
2023-08-14 |
Not clear |
| David S Dang, Chaoyu Zhai, Mahesh N Nair, Kara J Thornton, Mohammed N Sawalhah, Sulaiman K Matarne. Tandem mass tag labeling to assess proteome differences between intermediate and very tender beef steaks. Journal of animal science. vol 100. issue 8. 2022-07-31. PMID:35908783. |
the differentially identified proteins encompassed a wide array of biological processes related to muscle contraction, calcium signaling, metabolism, extracellular matrix organization, chaperone, and apoptosis. |
2022-07-31 |
2023-08-14 |
Not clear |
| Zheming Bao, Mengli Chen, Chen Li, Qing Shan, Yichen Wang, Wenshan Yan. Monosodium iodoacetate-induced subchondral bone microstructure and inflammatory changes in an animal model of osteoarthritis. Open life sciences. vol 17. issue 1. 2022-07-29. PMID:35903181. |
we found that intra-articular injection of mia increased chondrocyte apoptosis and promoted cartilage matrix degradation, such as cartilage surface defects and shallow or disappearing staining. |
2022-07-29 |
2023-08-14 |
rat |
| Zhao Zhang, Jingtao Wu, Cheng Teng, Jinquan Wang, Libo Wang, Long Wu, Wenhao Chen, Zhen Lin, Zhongke Li. Safranal Treatment Induces Sirt1 Expression and Inhibits Endoplasmic Reticulum Stress in Mouse Chondrocytes and Alleviates Osteoarthritis Progression in a Mouse Model. Journal of agricultural and food chemistry. 2022-07-28. PMID:35899925. |
oxidative stress (os) modulates oa pathogenesis by enhancing chondrocyte apoptosis and extracellular matrix (ecm) degeneration via activation of the endoplasmic reticulum (er) stress. |
2022-07-28 |
2023-08-14 |
mouse |
| Mamdouh Eldesoqui, Zienab Helmy Eldken, Sally Abdallah Mostafa, Rasha Hamed Al-Serwi, Mohamed El-Sherbiny, Nehal Elsherbiny, Zuhair M Mohammedsaleh, Noha Hammad Sak. Exercise Augments the Effect of SGLT2 Inhibitor Dapagliflozin on Experimentally Induced Diabetic Cardiomyopathy, Possible Underlying Mechanisms. Metabolites. vol 12. issue 7. 2022-07-27. PMID:35888760. |
dcm is associated with myocardial oxidative stress, inflammation, apoptosis, suppressed autophagy, extracellular matrix remodeling, and fibrosis. |
2022-07-27 |
2023-08-14 |
rat |
| Wei Tan, Yunyan Wang, Hongmei Dai, Junhui Deng, Zhifen Wu, Lirong Lin, Jurong Yan. Potential Therapeutic Strategies for Renal Fibrosis: Cordyceps and Related Products. Frontiers in pharmacology. vol 13. 2022-07-25. PMID:35873549. |
in this paper, we review the potential mechanisms of cordyceps against renal fibrosis, focusing on the effects of cordyceps on inflammation, oxidative stress, apoptosis, regulation of autophagy, reduction of extracellular matrix deposition, and fibroblast activation. |
2022-07-25 |
2023-08-14 |
Not clear |
| Daokuan Gao, Bo Hu, Baiyang Ding, Quanlai Zhao, Yu Zhang, Liang Xia. N6-Methyladenosine-induced miR-143-3p promotes intervertebral disc degeneration by regulating SOX5. Bone. 2022-07-25. PMID:35878746. |
mir-143-3p in nucleus pulposus cells was involved in the regulation of extracellular matrix metabolism and apoptosis after tnf-α stimulation, and intervertebral disc degeneration was relieved by effectively regulating mir-143-3p expression. |
2022-07-25 |
2023-08-14 |
human |
| Chu-Yang Zeng, Xi-Feng Wang, Fu-Zhou Hu. HIF-1α in Osteoarthritis: From Pathogenesis to Therapeutic Implications. Frontiers in pharmacology. vol 13. 2022-07-22. PMID:35865944. |
the activation of hif-1α could regulate autophagy and apoptosis of chondrocytes, decrease inflammatory cytokine synthesis, and regulate the chondrocyte extracellular matrix environment. |
2022-07-22 |
2023-08-14 |
Not clear |
| Yonggan Ying, Zhaopeng Tang, Feng Niu, Taotao Xu, Chenjie Xia, Shuijun Zhan. Network pharmacology-based pharmacological mechanism prediction on Eucommia ulmoides against rheumatoid arthritis. Medicine. vol 101. issue 29. 2022-07-22. PMID:35866805. |
go enrichment analysis indicated that eu exerted antira effects depending on regulating multiple biological processes including inflammatory response, oxidative stress, cell apoptosis and matrix catabolism. |
2022-07-22 |
2023-08-14 |
Not clear |