| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dan Li, Dongdong Luo, Hu Su, Hailin Zhao, Biao Pen. Syringic acid suppressed proliferation, invasion, and migration via inhibition of matrix metalloproteinases expression on glioblastoma cells by promoting apoptosis. Current pharmaceutical biotechnology. 2022-05-16. PMID:35570553. |
syringic acid suppressed proliferation, invasion, and migration via inhibition of matrix metalloproteinases expression on glioblastoma cells by promoting apoptosis. |
2022-05-16 |
2023-08-13 |
human |
| Massimiliano Marvasi, Monica Monici, Desirée Pantalone, Duccio Cavalier. Exploitation of Skin Microbiota in Wound Healing: Perspectives During Space Missions. Frontiers in bioengineering and biotechnology. vol 10. 2022-05-16. PMID:35573226. |
microgravity and possible physical factors associated with space affect alterations in fibroblast, matrix formation, dysregulation in apoptosis and inflammation. |
2022-05-16 |
2023-08-13 |
human |
| Chao-Peng He, Cheng Chen, Xin-Chen Jiang, Hui Li, Li-Xin Zhu, Ping-Xiao Wang, Tao Xia. The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis. Bone & joint research. vol 11. issue 5. 2022-05-13. PMID:35549515. |
in recent years, it has been found that ages are involved in a variety of pathological processes of oa, including extracellular matrix degradation, chondrocyte apoptosis, and autophagy. |
2022-05-13 |
2023-08-13 |
Not clear |
| Lixia Gao, Xiaoyun Wang, Jian Xiong, Yan M. Circular RNA from phosphodiesterase 4D can attenuate chondrocyte apoptosis and matrix degradation under OA milieu induced by IL-1β via circPDE4D/miR-4306/SOX9 cascade. Immunopharmacology and immunotoxicology. 2022-05-13. PMID:35549803. |
circular rna from phosphodiesterase 4d can attenuate chondrocyte apoptosis and matrix degradation under oa milieu induced by il-1β via circpde4d/mir-4306/sox9 cascade. |
2022-05-13 |
2023-08-13 |
human |
| Edward Hurley, Junyan Tao, Silvia S Liu, Yekaterina Krutsenko, Satdarshan P Mong. HSF1 Signaling Inhibits Apoptosis in Hepatoblastoma. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554956. |
recent work has shown that hsf1 controls a suite of genes in cancer related to apoptosis, cell cycle signaling, dna repair, energy metabolism and extracellular matrix formation. |
2022-05-13 |
2023-08-13 |
mouse |
| Faihaa Ahmed, Shaymaa Abousaad, Ayman Abouzeid, Elimelda Onger. Meprin β mediates Osteopontin-Signaling in IR-Induced Acute Kidney Injury. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555103. |
opn mediates cell signaling pathways involved in apoptosis and extracellular matrix metabolism. |
2022-05-13 |
2023-08-13 |
mouse |
| Vasileios Kapralos, Jannis Böcker, Kirstin Vach, Markus Altenburger, Susanne Proksch, Lamprini Karygiann. On the biocompatibility of endodontic sealers. Swiss dental journal. vol 132. issue 9. 2022-05-10. PMID:35536041. |
while all sealers influenced the cell morphology and the expression of genes associated with apoptosis (casp3), proliferation (histone h3), and inflammation (interleukin-6 and matrix metalloproteinases 1 and 3), mainly ah plus® and apexit® yielded a regular actin cytoskeleton and beneficial gene expression patterns. |
2022-05-10 |
2023-08-13 |
human |
| Minglei Qian, Yuanxin Shi, Wei L. LINC00707 knockdown inhibits IL-1β-induced apoptosis and extracellular matrix degradation of osteoarthritis chondrocytes by the miR-330-5p/FSHR axis. Immunopharmacology and immunotoxicology. 2022-05-10. PMID:35536095. |
linc00707 knockdown inhibits il-1β-induced apoptosis and extracellular matrix degradation of osteoarthritis chondrocytes by the mir-330-5p/fshr axis. |
2022-05-10 |
2023-08-13 |
Not clear |
| Jialing Xiao, Yali Li, Gang Cheng, Guochao X. Zoledronate promotes ECM degradation and apoptosis via Wnt/β-catenin. Open medicine (Warsaw, Poland). vol 17. issue 1. 2022-05-09. PMID:35529473. |
cell viability, apoptosis, mrna, and protein expression of relevant genes involved in extracellular matrix (ecm) degradation, apoptosis, and wnt/β-catenin signaling were examined. |
2022-05-09 |
2023-08-13 |
rabbit |
| Kai Sun, Li-Guo Zhu, Xu Wei, He Yin, Jia-Wen Zhan, Xun-Lu Yin, Tao Ha. [Research progress in mechanism of Chinese herbal compounds and monomers in delaying lumbar intervertebral disc degeneration]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 9. 2022-05-09. PMID:35531687. |
the main molecular mechanisms by which herbal compound and monomeric components delay of lumbar intervertebral disc degeneration include improving the intervertebral disc microenvironment, promoting the synthesis of aggregated proteoglycans and type Ⅱ collagen in the intervertebral disc, reducing the degradation of the extracellular matrix, and inhibiting apoptosis in the nucleus pulposus cells, etc. |
2022-05-09 |
2023-08-13 |
Not clear |
| Chaofan Zhang, Yunzhi Lin, Chun Hoi Yan, Wenming Zhan. Adipokine Signaling Pathways in Osteoarthritis. Frontiers in bioengineering and biotechnology. vol 10. 2022-05-06. PMID:35519618. |
increasing evidence show that various adipokines may significantly affect the development or clinical course of oa by regulating the pro/anti-inflammatory and anabolic/catabolic balance, matrix remodeling, chondrocyte apoptosis and autophagy, and subchondral bone sclerosis. |
2022-05-06 |
2023-08-13 |
Not clear |
| I Yilmaz, N Karaarsla. Examining the effects of HMG-CoA reductase inhibitors on anabolic and catabolic signaling pathway proteins associated with degenerative disc disease. European review for medical and pharmacological sciences. vol 26. issue 8. 2022-05-03. PMID:35503599. |
additionally, nuclear factor kappa b (nf-κb) is reported to be suppressed in statin-administered nucleus pulposus (np) cells for the prevention of interleukin (il) -1 beta (il-1β)-induced apoptosis and extracellular matrix (ecm) degradation. |
2022-05-03 |
2023-08-13 |
human |
| G-M Cao, X-Z Xuan, H-L Don. Low expression of integrin signaling pathway genes is associated with abdominal aortic aneurysm: a bioinformatic analysis by WGCNA. European review for medical and pharmacological sciences. vol 26. issue 8. 2022-05-03. PMID:35503629. |
aaa is pathologically distinguished by atherosclerotic thrombosis, immune cell infiltration, smooth muscle cell apoptosis, and extracellular matrix degradation. |
2022-05-03 |
2023-08-13 |
Not clear |
| Olesya A Puchenkova, Vladislav O Soldatov, Andrei E Belykh, OlgaYu Bushueva, Gennadii A Piavchenko, Artem A Venediktov, Nikolay K Shakhpazyan, Alexey V Deykin, Mikhail V Korokin, Mikhail V Pokrovski. Cytokines in Abdominal Aortic Aneurysm: Master Regulators With Clinical Application. Biomarker insights. vol 17. 2022-05-02. PMID:35492378. |
all the inflammatory cascades, extracellular matrix degradation and vascular smooth muscle cell apoptosis are driven by cytokines. |
2022-05-02 |
2023-08-13 |
Not clear |
| Jingguo Xin, Yongjie Wang, Zhi Zheng, Shuo Wang, Shibo Na, Shaokun Zhan. Treatment of Intervertebral Disc Degeneration. Orthopaedic surgery. 2022-04-29. PMID:35486489. |
the pathological changes of idd are mainly composed of the senescence and apoptosis of nucleus pulposus cells (npcs), the progressive degeneration of extracellular matrix (ecm), the fibrosis of annulus fibrosus (af), and the inflammatory response. |
2022-04-29 |
2023-08-13 |
Not clear |
| Yijian Zhang, Tao Liu, Huilin Yang, Fan He, Xuesong Zh. Melatonin: A Novel Candidate for the Treatment of Osteoarthritis. Ageing research reviews. 2022-04-28. PMID:35483626. |
with regards to oa, melatonin reportedly promotes synthesis of cartilage matrix, inhibition of chondrocyte apoptosis, attenuation of inflammatory response, and suppression of matrix degradation by regulating the tgf-β, mapk, or nf-κb signaling pathways. |
2022-04-28 |
2023-08-13 |
Not clear |
| Guowen Li, Heyuan Luo, Zhiyong Ding, Haofeng Liang, Zhoupeng Lai, Shuzhen Chen, Yuliang Huan. Silencing of circ_0000205 mitigates interleukin-1β-induced apoptosis and extracellular matrix degradation in chondrocytes via targeting miR-766-3p/ADAMTS5 axis. Innate immunity. vol 28. issue 2. 2022-04-28. PMID:35484121. |
silencing of circ_0000205 mitigates interleukin-1β-induced apoptosis and extracellular matrix degradation in chondrocytes via targeting mir-766-3p/adamts5 axis. |
2022-04-28 |
2023-08-13 |
Not clear |
| Guowen Li, Heyuan Luo, Zhiyong Ding, Haofeng Liang, Zhoupeng Lai, Shuzhen Chen, Yuliang Huan. Silencing of circ_0000205 mitigates interleukin-1β-induced apoptosis and extracellular matrix degradation in chondrocytes via targeting miR-766-3p/ADAMTS5 axis. Innate immunity. vol 28. issue 2. 2022-04-28. PMID:35484121. |
cell proliferation, apoptosis, and extracellular matrix (ecm) synthesis were examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and 5-ethynyl-2-deoxyuridine assays, flow cytometry, and qrt-pcr and western blot assays. |
2022-04-28 |
2023-08-13 |
Not clear |
| Guowen Li, Heyuan Luo, Zhiyong Ding, Haofeng Liang, Zhoupeng Lai, Shuzhen Chen, Yuliang Huan. Silencing of circ_0000205 mitigates interleukin-1β-induced apoptosis and extracellular matrix degradation in chondrocytes via targeting miR-766-3p/ADAMTS5 axis. Innate immunity. vol 28. issue 2. 2022-04-28. PMID:35484121. |
il-1β treatment could attenuate cell viability of primary chondrocytes and proliferating cell nuclear antigen (pcna) and collagen ii type alpha-1 (col2a1) levels, and elevate apoptosis rate and cleaved caspase-3, adamts5 and matrix metalloproteinase-13 (mmp13) levels, suggesting that il-1β induced chondrocyte apoptosis and ecm degradation. |
2022-04-28 |
2023-08-13 |
Not clear |
| Shunlun Chen, Linchuan Lei, Zemin Li, Fan Chen, Yuming Huang, Guowei Jiang, Xingyu Guo, Zhuoyang Zhao, Hui Liu, Hua Wang, Caijun Liu, Zhaomin Zheng, Jianru Wan. Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation. Experimental & molecular medicine. 2022-04-20. PMID:35440754. |
these results indicated that the expression of grem1 was positively correlated with the severity of intervertebral disc degeneration, and grem1 sirna could inhibit grem1-induced apoptosis and extracellular matrix alterations by mediating the tgf-β/smad signaling pathway. |
2022-04-20 |
2023-08-13 |
human |