| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexandra Ripszky Totan, Marina Melescanu Imre, Simona Parvu, Daniela Meghea, Radu Radulescu, Dan Sebastian Alexandru Enasescu, Mihai Radu Moisa, Silviu Mirel Pitur. Autophagy Plays Multiple Roles in the Soft-Tissue Healing and Osseointegration in Dental Implant Surgery-A Narrative Review. Materials (Basel, Switzerland). vol 15. issue 17. 2022-09-09. PMID:36079421. |
autophagy downregulation in fibroblasts induces apoptosis, leading to better wound healing by improving excessive deposition of extracellular matrix and inhibiting fibrosis progression. |
2022-09-09 |
2023-08-14 |
Not clear |
| Chao Jia, Xiucui Li, Jun Pan, Haiwei Ma, Dengying Wu, Hongwei Lu, Wei Wang, Xutong Zhang, Xianhong Y. Silencing of Angiopoietin-Like Protein 4 (Angptl4) Decreases Inflammation, Extracellular Matrix Degradation, and Apoptosis in Osteoarthritis via the Sirtuin 1/NF- Oxidative medicine and cellular longevity. vol 2022. 2022-09-08. PMID:36071864. |
silencing of angiopoietin-like protein 4 (angptl4) decreases inflammation, extracellular matrix degradation, and apoptosis in osteoarthritis via the sirtuin 1/nf- osteoarthritis (oa) is a frequently observed condition in aged people. |
2022-09-08 |
2023-08-14 |
mouse |
| Chao Jia, Xiucui Li, Jun Pan, Haiwei Ma, Dengying Wu, Hongwei Lu, Wei Wang, Xutong Zhang, Xianhong Y. Silencing of Angiopoietin-Like Protein 4 (Angptl4) Decreases Inflammation, Extracellular Matrix Degradation, and Apoptosis in Osteoarthritis via the Sirtuin 1/NF- Oxidative medicine and cellular longevity. vol 2022. 2022-09-08. PMID:36071864. |
oa cartilage is characterized by chondrocyte apoptosis, chondrocyte inflammation, and hyperactive catabolism of extracellular matrix. |
2022-09-08 |
2023-08-14 |
mouse |
| Manabu Sakai, Takayoshi Saka. Establishment of a Mouse Submandibular Salivary Gland Organ Culture. Current protocols. vol 2. issue 9. 2022-09-07. PMID:36069677. |
under physiological conditions, cells constantly interact with other cells and the extracellular matrix, which controls complex biological functions such as cell migration and apoptosis, and can modulate gene expression. |
2022-09-07 |
2023-08-14 |
mouse |
| Lorena Cayetano-Salazar, Dania A Nava-Tapia, Kevin D Astudillo-Justo, Adán Arizmendi-Izazaga, César Sotelo-Leyva, Mayra Herrera-Martinez, Sócrates Villegas-Comonfort, Napoleón Navarro-Tit. Flavonoids as regulators of TIMPs expression in cancer: Consequences, opportunities, and challenges. Life sciences. 2022-09-06. PMID:36067841. |
these inhibitors regulate tissue extracellular matrix (ecm) turnover; they inhibit matrix metalloproteinases (mmps), cell migration, invasion, and angiogenesis and induce apoptosis in tumor cells. |
2022-09-06 |
2023-08-14 |
Not clear |
| ChuanCai Liang, Hengte Xing, ChenYu Wang, XiongFeng Xu, Yarong Hao, Bo Qi. Resveratrol protection against IL-1β-induced chondrocyte damage via the SIRT1/FOXO1 signaling pathway. Journal of orthopaedic surgery and research. vol 17. issue 1. 2022-09-05. PMID:36064420. |
this study investigated the effects of resveratrol (res) on extracellular matrix (ecm), autophagy, and apoptosis in oa pathogenesis via the sirt1/foxo1 pathway. |
2022-09-05 |
2023-08-14 |
Not clear |
| Rais Reskiawan A Kadir, Mansour Alwjwaj, Kamini Rakkar, Othman Ahmad Othman, Nikola Sprigg, Philip M Bath, Ulvi Bayraktuta. Outgrowth Endothelial Cell Conditioned Medium Negates TNF-α-Evoked Cerebral Barrier Damage: A Reverse Translational Research to Explore Mechanisms. Stem cell reviews and reports. 2022-09-02. PMID:36056287. |
effective suppression of anti-angiogenic factor endostatin, stress fiber formation, oxidative stress, and apoptosis along with concomitant improvements in extracellular matrix adhesive and tubulogenic properties of brain microvascular endothelial cells and oecs played an important role in oec-cm-mediated benefits. |
2022-09-02 |
2023-08-14 |
human |
| Chao Wan, Wei Liu, Limin Jiang, Shengjie Dong, Weihua Ma, Shijun Wang, Dan Li. Knockdown of MKL1 ameliorates oxidative stress-induced chondrocyte apoptosis and cartilage matrix degeneration by activating TWIST1-mediated PI3K/AKT signaling pathway in rats. Autoimmunity. 2022-09-01. PMID:36046946. |
knockdown of mkl1 ameliorates oxidative stress-induced chondrocyte apoptosis and cartilage matrix degeneration by activating twist1-mediated pi3k/akt signaling pathway in rats. |
2022-09-01 |
2023-08-14 |
rat |
| Chao Wan, Wei Liu, Limin Jiang, Shengjie Dong, Weihua Ma, Shijun Wang, Dan Li. Knockdown of MKL1 ameliorates oxidative stress-induced chondrocyte apoptosis and cartilage matrix degeneration by activating TWIST1-mediated PI3K/AKT signaling pathway in rats. Autoimmunity. 2022-09-01. PMID:36046946. |
this study aimed to investigate the regulatory role of mkl1 in oxidative stress-induced chondrocyte apoptosis and cartilage matrix degeneration. |
2022-09-01 |
2023-08-14 |
rat |
| Anna Ruiz-Mitjana, Raúl Navaridas, Maria Vidal-Sabanés, Aida Perramon-Güell, Andree Yeramian, Isidre Felip, Núria Eritja, Joaquim Egea, Mario Encinas, Xavier Matias-Guiu, Xavier Dolce. Lack of extracellular matrix switches TGF-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition. Scientific reports. vol 12. issue 1. 2022-09-01. PMID:36050359. |
lack of extracellular matrix switches tgf-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition. |
2022-09-01 |
2023-08-14 |
Not clear |
| Anna Ruiz-Mitjana, Raúl Navaridas, Maria Vidal-Sabanés, Aida Perramon-Güell, Andree Yeramian, Isidre Felip, Núria Eritja, Joaquim Egea, Mario Encinas, Xavier Matias-Guiu, Xavier Dolce. Lack of extracellular matrix switches TGF-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition. Scientific reports. vol 12. issue 1. 2022-09-01. PMID:36050359. |
here, we have demonstrated that the lack of extracellular matrix and consequent loss of cell polarity inhibits tgf-β-induced apoptosis, observed when endometrial epithelial cells are polarized in presence of extracellular matrix. |
2022-09-01 |
2023-08-14 |
Not clear |
| Chenyu Rao, Sirong Sh. Development of Nanomaterials to Target Articular Cartilage for Osteoarthritis Therapy. Frontiers in molecular biosciences. vol 9. 2022-08-29. PMID:36032667. |
after administration, the dds and targeted nano therapeutical molecules can specifically react with the components, including cartilage and synovium of a joint in oa, furthermore attenuate the chondrocyte apoptosis, matrix degradation, and macrophage recruitment. |
2022-08-29 |
2023-08-14 |
Not clear |
| Junjun Mao, Xinping Wang, Minghui Yu, Chenkun Su. Effects of Atractylon on Proliferation and Apoptosis of Intestinal Cancer Cells Through PI3K/AKT/mTOR Signaling Pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 5. 2022-08-27. PMID:36029491. |
the content of interferon-γ (inf-γ), tumor necrosis factor-α (tnf-α) and matrix metalloproteinase-9 (mmp-9) was detected via enzyme-linked immunosorbent assay (elisa), and the apoptosis of ht29 cells was detected through terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) staining. |
2022-08-27 |
2023-08-14 |
Not clear |
| Paulina Borzdziłowska, Ilona Bednare. Alpha Mangostin and Cisplatin as Modulators of Exosomal Interaction of Ovarian Cancer Cell with Fibroblasts. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012171. |
in our study, we observed altered expression of genes involved in various steps of the metastasis process (including genes related to cell adhesion, genes related to the interaction with the extracellular matrix, the cell cycle, cell growth and proliferation, and apoptosis). |
2022-08-26 |
2023-08-14 |
human |
| Taneli T Mattila, Madhura Patankar, Juha P Väyrynen, Kai Klintrup, Jyrki Mäkelä, Anne Tuomisto, Pentti Nieminen, Markus J Mäkinen, Tuomo J Karttune. Putative anoikis resistant subpopulations are enriched in lymph node metastases and indicate adverse prognosis in colorectal carcinoma. Clinical & experimental metastasis. 2022-08-26. PMID:36018456. |
anoikis refers to apoptosis induced by the loss of contact with the extracellular matrix. |
2022-08-26 |
2023-08-14 |
Not clear |
| Suhnrita Chaudhuri, Sagar Acharya, Swapna Chaudhur. Therapeutic intervention of glioma with the novel antineoplastic agent T11TS: the story so far. Immunotherapy. 2022-08-25. PMID:36004447. |
t11ts hinders endothelial cell progression and metastasis by arresting matrix degradation, inhibiting the ras-raf and akt-pten pathways and initiating inflammatory changes, causing apoptosis. |
2022-08-25 |
2023-08-14 |
Not clear |
| Argen Mamazhakypov, Meerim Sartmyrzaeva, Akpay Sh Sarybaev, Ralph Schermuly, Akylbek Sydyko. Clinical and Molecular Implications of Osteopontin in Heart Failure. Current issues in molecular biology. vol 44. issue 8. 2022-08-25. PMID:36005141. |
osteopontin influences myocardial remodeling by regulating extracellular matrix production, the activity of matrix metalloproteinases and various growth factors, inflammatory cell recruitment, myofibroblast differentiation, cardiomyocyte apoptosis, and myocardial vascularization. |
2022-08-25 |
2023-08-14 |
Not clear |
| Yiqiu Liu, Ye Liu, Junyu Deng, Xingqian Wu, Wenjie He, Xingrui Mu, Xuqiang Ni. Molecular mechanisms of Marine-Derived Natural Compounds as photoprotective strategies. International immunopharmacology. vol 111. 2022-08-23. PMID:35998505. |
excessive exposure of the skin to ultraviolet radiation (uvr) causes oxidative stress, inflammation, immunosuppression, apoptosis, and changes in the extracellular matrix, which lead to the development of photoaging and photodamage of skin. |
2022-08-23 |
2023-08-14 |
Not clear |
| Yiqiu Liu, Ye Liu, Junyu Deng, Xingqian Wu, Wenjie He, Xingrui Mu, Xuqiang Ni. Molecular mechanisms of Marine-Derived Natural Compounds as photoprotective strategies. International immunopharmacology. vol 111. 2022-08-23. PMID:35998505. |
it reviews the positive effects of mdncs in counteracting uv-induced oxidative stress, inflammation, dna damage, apoptosis, immunosuppression, and extracellular matrix degradation. |
2022-08-23 |
2023-08-14 |
Not clear |
| Cheng-Chen Zhang, Ting Wu, Li Guan, Yu-Jue Wang, Rui-Qin Yao, Dian-Shuai Gao, Feng L. Effects of STAT3 Inhibitor BP-1-102 on The Proliferation, Invasiveness, Apoptosis and Neurosphere Formation of Glioma Cells in Vitro. Cell biochemistry and biophysics. 2022-08-22. PMID:35994220. |
furthermore, bp-1-102 inhibited the invasion and migration abilities of u251 and a172 cells by decreasing the expression of matrix metallopeptidase 9, and induced glioma cell apoptosis by decreasing the expression of b-cell lymphoma-2. |
2022-08-22 |
2023-08-14 |
Not clear |